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Patent # Description
2016/0324997 DECONTAMINATION METHOD AND APPARATUS
Provided is an apparatus for disinfecting objects of various shapes and sizes. The apparatus includes a housing enclosing a disinfecting chamber, and an...
2016/0324996 Medical Device Treatment
An ultraviolet illuminator for providing a cleaning treatment to a medical device is disclosed. The ultraviolet illuminator can include an ultraviolet cleaning...
2016/0324995 DEVICE AND METHOD FOR TRANSFERRING A STERILE PRODUCT BETWEEN TWO CONTAINERS
A device for transferring a sterile product from one container to another under aseptic conditions. The first container to initially contain the sterile...
2016/0324994 ULTRASONIC THERMAL DISINFECTOR
Provided is a thermal disinfector including a cover, a basin, at least an inlet for water, an outlet to drain the water into the sewer, an outlet for...
2016/0324993 NON-INVASIVE DIAGNOSTIC AGENTS OF CANCER AND METHODS OF DIAGNOSING CANCER, ESPECIALLY LEUKEMIA AND LYMPHOMA
The present invention is directed to novel non-invasive diagnostic tools to image cancers, especially, leukemia and non-Hodgkin's lymphomas (NHL) with minimal...
2016/0324992 IDENTIFICATION AND TREATMENT OF VULNERABLE PLAQUES
A method of detecting an atherosclerotic plaque vulnerable to rupture in a subject comprises providing to the subject a labelled necrostatin or a derivative...
2016/0324991 Multiplexed In Vivo Screening Of Biological Samples
Microfabricated platforms can be used to study a heterogeneous panel of biosamples in a realistic in vivo setting. The platform can be formed of a polymer...
2016/0324990 Method For Using Nanodiamonds To Detect Nearby Magnetic Nanoparticles
An imaging agent for detecting analytes in an environment includes functionalized nanodiamonds and functionalized magnetic particles that can selectively...
2016/0324989 METHODS FOR ENHANCING THE DELIVERY OF ACTIVE AGENTS
A method of increasing blood-brain barrier permeability of selected brain tissue in a subject in need thereof is carried out by: (a) parenterally administering...
2016/0324988 Hydrodynamic Methods for Delivering Fluids to Kidney Tissues and Related Materials and Methods
The present invention provides methods and materials useful delivering liquids, including liquids comprising nucleic acid molecules into cells. In particular,...
2016/0324987 USE OF CRISPR/CAS9 AS IN VIVO GENE THERAPY TO GENERATE TARGETED GENOMIC DISRUPTIONS IN GENES BEARING DOMINANT...
Described herein are methods and compositions for genomic editing. Clustered regularly interspaced short palindromic (CRISPR) allows for highly selective...
2016/0324986 COMPOSITIONS AND METHODS FOR PROVIDING ACTIVE TELOMERASE TO CELLS IN VIVO
This invention provides liposomes for delivering to target cells in a subject, nucleic acids for expressing telomerase reverse transcriptase and/or telomerase...
2016/0324985 HYDROGELS CONTAINING EMBEDDED SUBSTRATES FOR TARGETED BINDING OF MOLECULES
Open three-dimensional network, microporous hydrogels containing substrates attached to binding molecules is disclosed. The hydrogel is comprised of a hydrated...
2016/0324984 BIOSPECIFIC ANTI-HAPTEN/ANTI-BLOOD BRAIN BARRIER RECEPTOR ANTIBODIES, COMPLEXES THEREOF AND THEIR USE AS BLOOD...
Herein is reported a bispecific antibody comprising a first binding specificity that specifically binds to a haptenylated payload and a second binding...
2016/0324983 Compounds and Compositions for Immunotherapy
Provided are compounds for targeted immunotherapy. The compounds are useful in the treatment of diseases such as cancer. Also provided are compositions...
2016/0324982 COMPOSITIONS AND METHODS FOR NON-MYELOABLATIVE CONDITIONING
Disclosed herein are non-myeloablative antibody-toxin conjugates and compositions that target cell surface markers, such as the CD34, CD45 or CD117 receptors,...
2016/0324981 LIVER X RECEPTOR AGONISTS AND USES THEREOF
Disclosed herein are antibody drug conjugates having an antibody or antibody fragment that binds a cell surface molecule on a target cell, wherein the target...
2016/0324980 METHODS OF PREPARATION OF CONJUGATES
The present invention is directed to methods of preparing a conjugate of a cell-binding agent and a drug (such as a cytotoxic compound). The methods comprise...
2016/0324979 METHOD FOR PURIFYING CYS-LINKED ANTIBODY-DRUG CONJUGATES
The present invention relates to a method for purifying a mixture of cysteine-linked antibody-drug conjugates, wherein the amount of non-conjugated antibody is...
2016/0324978 HYPERICIN ALBUMIN NANOPARTICLE-ESCHERICHIA COLI SERUM ANTIBODY COMPLEX AND PREPARATION METHOD AND APPLICATION...
The present invention discloses a hypericin albumin nanoparticle-Escherichia coli serum antibody complex, which is obtained through adding mixed hypericin...
2016/0324977 PEPTIDE DENDRIMERS COMPRISING FIBRINOGEN-BINDING PEPTIDES
Peptide dendrimers and agents are described, which can be used for polymerising fibrinogen and as haemostatic agents. The peptide dendrimers comprise a...
2016/0324976 PEPTIDE HAVING CELL MEMBRANE PENETRATING ACTIVITY
Provided are transmembrane complexes that contain a protein transduction domain (PTD) from the N-terminus of IgE-dependent histamine-releasing factor (HRF) and...
2016/0324975 REVERSIBLE PEGYLATED DRUGS
Reversible pegylated drugs are provided by derivatization of free functional groups of the drug selected from amino, hydroxyl, mercapto, phosphate and/or...
2016/0324974 METHOD FOR PREPARING A POLYMERIC REAGENT
Pharmaceutical compositions of conjugates are provided. The conjugates can be prepared by (among other ways) conjugating a pharmacologically active agent with...
2016/0324973 COMPOSITION COMPRISING A POLYMERIC REAGENT
The present invention provides among other things a composition of a polymeric reagent and an antioxidant, such as butylated hydroxyl toluene.
2016/0324972 TREATMENT OF MENINGEAL AND NEURAL DISEASES
The present invention provides conjugates and methods of using the same for the treatment of cerebral, meningeal, and neural diseases, disorders, and...
2016/0324971 FORMULATION FOR TOPICAL WOUND TREATMENT
The present invention relates to new formulations, particularly useful in the topical treatment of skin and oromucosal wounds. Formulations can be either a...
2016/0324970 PROTEIN TRANSDUCTION DOMAINS MIMICS
The invention generally relates to synthetic mimics of cell penetrating peptides. More particularly, the invention relates to certain novel monomers, oligomers...
2016/0324969 HYDROGEL FORMULATION WITH MILD ADHESION
The present disclosure relates to methods, compositions, and devices for treatments related to mammary tissue in subjects, including reducing the incidence of...
2016/0324968 LINACLOTIDE COMPOSITIONS
The present invention is directed to stable linaclotide compositions and methods of treating gastrointestinal disorders in patients in need thereof by...
2016/0324967 AQUEOUS PHARMACEUTICAL COMPOSITIONS CONTAINING BORATE-POLYOL COMPLEXES
The present invention is directed to the provision of multi-dose, ophthalmic compositions. The compositions possess sufficient antimicrobial activity to...
2016/0324966 POLYMERIC NANOCARRIERS WITH LIGHT-TRIGGERED RELEASE MECHANISM
Near infrared radiation at a wavelength that induces resonance in water is used to remotely activate thermal plasticization of polymeric particles to trigger...
2016/0324965 MONOCLONAL ANTIBODY COCKTAILS FOR TREATMENT OF EBOLA INFECTIONS
Antibody variants originating from the monoclonal antibody 13C6, and wherein the N-glycosylation site within the constant region of the heavy chain contains a...
2016/0324964 CANCER TREATMENTS
This document provides methods and materials related to treating cancer (e.g., skin cancer). For example, methods and materials relating to the use of a...
2016/0324963 COMBINATION THERAPIES EMPLOYING GITR BINDING MOLECULES
The present invention provides combination therapies that employ a GITR binding molecule in combination with one or more additional agents.
2016/0324962 COMPOSITIONS AND METHODS FOR TREATING SARCOMA
The present invention provides compositions and methods for the treatment of sarcoma. The compositions comprise an antibody that binds at least one of IGF-1...
2016/0324961 Methods for Treating Cancer with DLL4 Antagonists
The present invention provides methods for treating cancer. More particularly, the invention provides methods for treating cancer comprising administrating...
2016/0324960 ADJUVANT FOR MUCOSAL VACCINE
An object of the present invention is to provide an adjuvant for a mucosal vaccine with high safety that induces a sufficient immune response on the mucosa....
2016/0324959 ALUMINUM COMPOUNDS FOR USE IN THERAPEUTICS AND VACCINES
The invention relates to means and methods for preparing aqueous composition comprising aluminium and a protein said composition comprising less than 700 ppm...
2016/0324958 FLAGELLIN-CONTAINING PROTEIN NANOPARTICLES AS A VACCINE PLATFORM
The present invention relates to self-assembling protein nanoparticles constructed from suitable oligomerization domains and further incorporating the TLR5...
2016/0324957 TEMPERATURE STABLE VACCINE FORMULATIONS
Vaccine antigen formulations that are stable after undergoing freeze and thaw conditions and methods of preparing the formulations are provided. Methods of...
2016/0324956 PEPTIDE PARTICLE FORMULATION
A composition as disclosed is comprised of a plurality of groups of particles. The particles are comprised of a biocompatible polymer which may be a co-polymer...
2016/0324955 METHOD OF PREVENTING ALLERGIES
The present invention relates to compositions and methods for preventing allergy in a subject. Particularly, the present invention relates to epicutaneous...
2016/0324954 IMMUNOGENIC COMPOSITIONS FOR INHIBITING HEPATITIS D VIRUS
Disclosed herein are isolated nucleic acids, compositions of isolated nucleic acids, and compositions of polypeptides that are useful for the generation,...
2016/0324953 DNA VACCINE AGAINST VIRUS OF YELLOW FEVER
The present invention relates to vaccines of DNA that code for specific viral sequences. The DNA vaccines against yellow fever according to the invention are...
2016/0324952 IMMUNITY ENHANCING THERAPEUTIC VACCINE FOR HPV AND RELATED DISEASES
An immunity enhancing therapeutic vaccine includes a gene vector based on recombinant adenovirus and three elements: 1) an HPV antigen including the E6 and E7...
2016/0324951 Compositions and Methods for Treatment of Bacterial Infections
A cell, isolated nucleic acid, vector, isolated polypeptide, and method of treating a bacterial infection are provided. The cell includes a modified...
2016/0324950 GROUP B STREPTOCOCCUS POLYSACCHARIDE-PROTEIN CONJUGATES, METHODS FOR PRODUCING CONJUGATES, IMMUNOGENIC...
The invention relates to immunogenic polysaccharide-protein conjugates comprising a capsular polysaccharide (CP) from Streptococcus agalactiae, commonly...
2016/0324949 Streptococcus pneumoniae capsular polysaccharides and conjugates thereof
The invention relates to isolated Streptococcus pneumoniae serotype 15B capsular polysaccharide and processes for their preparation. The invention also relates...
2016/0324948 Streptococcus pneumoniae capsular polysaccharides and conjugates thereof
The invention relates to activated Streptococcus pneumoniae serotype 10A, 22F or 33F polysaccharides and processes for their preparation. The invention also...
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