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Patent # Description
2016/0324947 PROLINE-RICH PEPTIDES PROTECTIVE AGAINST S. PNEUMONIAE
The invention relates to lipopeptides consisting of a peptide chain comprising a parallel coiled-coil domain, a proline-rich peptide antigen, and a lipid...
2016/0324946 COMPOSITION AND THERAPEUTIC ANTI-TUMOUR VACCINE
The invention relates to a composition which induces, in a host, a cytotoxic cell response directed against cells expressing an antigen, in particular tumour...
2016/0324945 Immunogenic Fusion Proteins For The Treatment Of Cancer
Provided herein are compositions and methods for eliciting an immune response in a subject. In particular, the present disclosure is directed to immunogenic...
2016/0324944 Methods and compositions relating to p62/SQSTM1 for the treatment and prevention of inflammation-associated...
Provided herein are novel p62 compositions for the modulation of expression of a proinflammatory cytokines, osteogenic transcription factors, a bone resorptive...
2016/0324943 PROCESS FOR PRODUCTION OF BIVALIRUDIN
The invention relates to methods for the preparation of high purity Bivalirudin. The polypeptide is prepared in a high purity of at least 98.5% (by HPLC),...
2016/0324942 TPP-1 FORMULATIONS AND METHODS FOR TREATING CLN2 DISEASE
Formulations comprising recombinant human tripeptidyl peptidase-1 (rhTPP1) for intrathecal, intracerebroventricular, or intraocular administration, and kits...
2016/0324941 Microparticle Formulations for Delivery to the Lower and Central Respiratory Tract and Methods of Manufacture
Microparticle formulations of a sialidase fusion protein are produced by contacting an aqueous solution of a protein or other active agent with an organic...
2016/0324940 MRNA THERAPY FOR POMPE DISEASE
The present invention provides, among other things, methods of treating Pompe disease, including administering to a subject in need of treatment a composition...
2016/0324939 ANTI-MICROBIAL AGENTS AND USES THEREFOR
The invention relates generally to methods and materials (for example animal feeds) which use dextranases for treating or controlling Campylobacter infection...
2016/0324938 SEQUENCE SPECIFIC ANTIMICROBIALS
Provided are compositions and methods for selectively reducing the amount of antibiotic resistant and/or virulent bacteria in a mixed bacteria population, or...
2016/0324937 FRAGMENTS OF P97 AND USES THEREOF
Provided are fragments of human p97 (melanotransferrin) polypeptides having blood-brain barrier (BBB) transport activity, including variants and combinations...
2016/0324936 COMPOSITIONS AND METHOD FOR MANIPULATING PIM-1 ACTIVITY IN CIRCULATORY SYSTEM CELLS
The invention provides compositions (e.g., pharmaceutical compositions) comprising nucleic acids encoding the serine/threonine kinase PIM-1, and methods for...
2016/0324935 NITRIC OXIDE SYNTHASE NANOPARTICLES FOR TREATMENT OF VASCULAR DISEASE
A sustained-release composition for stimulating endothelial cell growth including a nitric oxide synthase within a nanoparticle comprising a biocompatible...
2016/0324934 METHODS AND PRODUCTS FOR NUCLEIC ACID PRODUCTION AND DELIVERY
The present invention relates in part to nucleic acids, including nucleic acids encoding proteins, therapeutics and cosmetics comprising nucleic acids, methods...
2016/0324933 ALBUMIN-BASED NON-COVALENT COMPLEXES AND METHODS OF USE THEREOF
A non-covalent complex of an albumin molecule and a hydrophobic ligand, compositions containing the same, and methods of use thereof are provided. The present...
2016/0324932 FUSION PROTEINS
The present invention relates to fusion proteins comprising an insulin receptor agonist fused to a human IgG Fc region through the use of a peptide linker, and...
2016/0324931 Use of Natriuretic Peptide for Treating Heart Failure
The present invention relates to the use of a natriurectic peptide, such as urodilatin, for treating a patient suffering from heart failure, such as acute...
2016/0324930 SYSTEMS AND METHODS FOR THERAPY OF KIDNEY DISEASE AND/OR HEART FAILURE USING CHIMERIC NATRIURETIC PEPTIDES
Medical systems and methods for treating kidney disease alone, heart failure alone, kidney disease with concomitant heart failure, or cardiorenal syndrome are...
2016/0324929 METHODS OF TREATING DISEASES ASSOCIATED WITH PPARy
The invention relates to methods for modulating PPAR-.gamma. activity using relaxin or agonists thereof. The result is wide range of new therapeutic regimens...
2016/0324928 Methods for treating blepharitis
The invention is directed to methods for treating blepharitis. The invention is further directed to reducing inflammation associated with blepharitis. The...
2016/0324927 COMPOSITIONS AND METHODS FOR IDENTIFYING, MODULATING AND MONITORING DRUG TARGETS IN MUSCULAR DISEASE
The present disclosure relates to customized therapy for disease. The present disclosure also relates to aptamer-based compositions and methods for...
2016/0324926 Use of CD83 in Combination Therapies
The present invention relates to improved methods of suppressing and/or preventing an undesired immune response comprising the use of CD83. In some...
2016/0324925 METHODS AND APPARATUS FOR CREATING PARTICLE DERIVATIVES OF HDL WITH REDUCED LIPID CONTENT
The present invention is directed to systems, apparatus and methods for creating derivatives of at least one form of HDL without substantially affecting LDL....
2016/0324924 COMPOSITIONS AND METHODS FOR TREATMENT OF EXERCISE-INDUCED PULMONARY HEMORRHAGE OR NASOPHARYNGEAL CICATRIX
Methods, compositions, and medical device systems relating to treating exercise-induced pulmonary hemorrhage (EIPH) and nasopharyngeal cicatrix (NC) in a...
2016/0324923 APOLIPOPROTEIN A-I MIMICS
Provided are peptides, compositions thereof, and methods for treating or preventing dyslipidemia, a cardiovascular disease, endothelial dysfunction, a...
2016/0324922 BETA-CASEIN A2 AND BLOOD GLUCOSE LEVELS
Regulating the level of glucose in the blood of an animal comprising the consumption by the animal of a composition containing beta-casein, or providing the...
2016/0324921 TREATMENT OF EYE DISEASE
A method of treating an eye disease comprising administering an adeno-associated virus (AAV) vector to a mammalian subject by subretinal injection, wherein the...
2016/0324920 Cellular Specific Therapeutic Prion
A method of inducing cell death or apoptosis in certain (undesirable) cells, such as cancerous cells or pathogenic microorganisms. The method to be described...
2016/0324919 COMPOSITIONS FOR USE IN THE TREATMENT OF ULCERATIVE COLITIS
An oral modified release composition comprising cyclosporin, wherein the composition is for use in the treatment of ulcerative colitis in a patient, wherein...
2016/0324918 TREATMENT OF LEAKY OR DAMAGED TIGHT JUNCTIONS AND ENHANCING EXTRACELLULAR MATRIX
Self assembling peptides and peptidomimetics can be utilized for the treatment and support of disorders associated with leaky or damaged tight junction and...
2016/0324917 COMPOSITIONS AND METHODS FOR PREVENTING AND REDUCING INFLAMMATION AND TREATING DISORDERS ASSOCIATED WITH...
The present invention relates to compositions and methods for preventing and reducing inflammation and preventing and treating diseases and disorders...
2016/0324916 PROCESS FOR THE SYNCHRONIZATION OF OVULATION FOR TIMED BREEDING WITHOUT HEAT DETECTION
A method for synchronizing ovulation in sows and gilts by a single injection of hormones is disclosed. A hormone, gonadotropin releasing hormone (GnRH),...
2016/0324915 Casein Peptide for Use in the Treatment of Uterine Infections
The present disclosure relates to a casein peptide for use in the treatment of an uterine infection in a female mammalian animal, to methods of treatment of...
2016/0324914 USE OF RICE BRAN OIL DISTILLATE EXTRACT FOR PREVENTION AND MITIGATION OF THE EFFECTS OF RADIATION
Provided herein is a tocol rich fraction of rice bran oil deodorized distillate that is shown to be both radioprotective and able to protect against oxidative...
2016/0324913 Enteric Coated Multiparticulate Controlled Release Peppermint Oil Composition and Related Methods
A multiparticulate composition is formed from a plurality of individual cores including a hydrophobic phase containing peppermint oil dispersed in a...
2016/0324912 METHODS TO ISOLATE ANTI-MICROBIALS FROM FRUIT OR SEED EXTRACTS
The invention provides a method of isolating one or more compounds present in fruit juice or seed extracts that have anti-microbial activity.
2016/0324911 COMPOSITIONS AND METHODS USEFUL IN TREATMENT OF LOWER URINARY TRACT SYMPTOMS, BENIGN PROSTATIC HYPERPLASIA,...
The invention relates to therapeutic compositions, solid oral dosage forms, and methods for treating, preventing, or alleviating lower urinary tract symptoms...
2016/0324910 HOMEOPATHIC THERAPEUTIC METHOD AND COMPOSITIONS
Methods of producing a Hydrophilic Homeopathic Aqueous Substance Active (HASA)-gel matrix, include the steps of: (a) combining a homeopathic compound and an...
2016/0324909 HYDROGENATION OF CANNABIS OIL
The present invention relates to the extraction and hydrogenation of essential oil of a cannabis plant. The invention includes hydrogenated cannabis compounds...
2016/0324908 Oil Exraction From Processed Hemp
Oil is extracted from processed hemp which is better suited for transportation than whole hemp stalks particularly when oil extraction and initial processing...
2016/0324907 POMEGRANATE SKIN EXTRACT FOR TREATING FATTY LIVER
Use of a pomegranate skin extract for use in the treatment of metabolic syndrome, more particularly, fatty liver disease. More particularly, the pomegranate...
2016/0324906 PHARMACEUTICAL COMPOSITION INCLUDING DEAD CELLS OF LACTOBACILLUS ACIDOPHILUS LB TO TREAT OR PREVENT ALLERGIC...
Disclosed is a pharmaceutical composition including dead cells of Lactobacillus acidophilus LB strain as an active ingredient for treating or preventing an...
2016/0324905 RECOMBINANT LACTOBACILLUS WITH DECREASED LIPOTEICHOIC ACID TO REDUCE INFLAMMATORY RESPONSES
Methods and compositions for treating or preventing inflammatory disorders are provided. The compositions of the invention comprise a recombinant bacterium...
2016/0324904 SUPPLEMENT FOR IMPROVING IMMUNOTOLERANCE, INTESTINAL ENVIRONMENT AND INTESTINAL TRACT BARRIER
A supplement for improving immunotolerance, intestinal environment and intestinal tract barrier for the purpose of improving intestinal vulnerability, food...
2016/0324903 LISTERIA-BASED ADJUVANTS
This invention provides methods and compositions for using Listeria monocytogenes as an adjuvant for enhancing immune responses in a subject.
2016/0324902 UMBILICAL CORD AMNIOTIC MEMBRANE PRODUCTS
Disclosed herein, in certain instances, are tissue grafts derived from UCAM. Further disclosed herein, in certain instances, are use for tissue grafts derived...
2016/0324901 Stem Cells Derived from Basal Portion of Chorionic Trophoblast Layer and Cell Therapy Comprising Same
The present disclosure relates to stem cells derived from the basal portion of the chorionic trophoblast layer (bCT), which is a part of the issues of the...
2016/0324900 LIVER STROMAL CELLS FOR PREVENTION AND TREATMENT OF IMMUNE RESPONSES IN TRANSPLANTATION
The present invention encompasses methods and compositions for reducing an immune response to a transplant in a recipient by treating said recipient with an...
2016/0324899 MULTIPOTENT AND IMMUNOCOMPATIBLE STEM CELL CONCENTRATE
The present invention generally relates to a stem cell concentrate isolated from a mammalian vascularized adipose tissue, biopharmaceuticals containing such...
2016/0324898 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
Compositions of mesenchymal stem cells and mesenchymal stem cell factors are provided. Methods of using the inventive compositions in the treatment of...
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