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Patent # Description
2016/0326597 DETERMINANTS OF CANCER RESPONSE TO IMMUNOTHERAPY
Molecular determinants of cancer response to immunotherapy are described, as are systems and tools for identifying and/or characterizing cancers likely to...
2016/0326596 COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF OVARIAN CANCERS THAT ARE ASSOCIATED WITH REDUCED...
Provided are compositions and methods for the identification and treatment of ovarian cancers, such as small cell ovarian cancers, in particular small cell...
2016/0326595 GENOMIC REARRANGEMENTS ASSOCIATED WITH PROSTATE CANCER AND METHODS OF USING THE SAME
The present disclosure provides genomic arrangements of the chromosome 3q13 region that are associated with prostate cancer, such as rearrangements between the...
2016/0326594 PROSTATE CANCER GENE PROFILES AND METHODS OF USING THE SAME
The present disclosure provides gene expression profiles that are associated with prostate cancer, including certain gene expression profiles that...
2016/0326593 COMPOSITIONS AND METHODS FOR DIAGNOSING, EVALUATING AND TREATING CANCER
The present invention relates to methods of determining a cancer treatment prognosis for a subject in need thereof by evaluating epigenetic and genetic changes...
2016/0326592 ALTERNATIVE SPLICE VARIANT PATTERNS OF HUMAN TELOMERASE REVERSE TRANSCRIPTASE (hTERT) IN THYROID TUMORS TO...
This invention relates, e.g., to a method for determining if a thyroid tumor in a subject is malignant, comprising determining in a sample from the subject the...
2016/0326591 COMPOSITIONS, KITS, AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION AND THERAPY OF BREAST AND OVARIAN CANCER
The invention relates to newly discovered nucleic acid molecules and proteins associated with breast or ovarian cancer. Compositions, kits, and methods for...
2016/0326590 TH17 DIFFERENTIATION MARKERS FOR ACNE AND USES THEREOF
A method is described for using IL-12R.beta.1/IL-23R, CCR6, BATF, AHR, STAT3, IRF4 crucial actors in Th17 cells differentiation as markers for acne. Also...
2016/0326589 METHOD OF DIAGNOSING PATIENTS WITH CONDITIONS CAUSED BY MENDELIAN MUTATION
The method of diagnosing patients with conditions caused by Mendelian mutations is a genetic panel-based diagnostic method for determining if a patient has a...
2016/0326588 MIRNAS AS NON-INVASIVE BIOMARKERS FOR PARKINSON'S DISEASE
The present invention relates to methods, kits and means for diagnosing Parkinson's disease in a blood sample from a subject. Further, the present invention...
2016/0326587 OVOL1 AS A NEW MARKER FOR MODERATE TO SEVERE ACNE
The invention relates to the identification of the ovo-like zinc finger 1 (OVOL1) as a new biomarker of moderate to severe acne. The invention also relates to...
2016/0326586 METHOD OF DETERMINING DISEASE CAUSALITY OF GENOME MUTATIONS
A method of identifying a gene or genomic mutation that is linked to causality of a neuropsychiatric disorder is provided. The method comprises identifying...
2016/0326585 INFLAMMATION-ENABLING POLYPEPTIDES AND USES THEREOF
This present technology relates to the use of inflammation-enabling polypeptides (or their coding sequences) to screen for agents useful for the prevention,...
2016/0326584 DIGITAL COUNTING OF INDIVIDUAL MOLECULES BY STOCHASTIC ATTACHMENT OF DIVERSE LABELS
Compositions, methods and kits are disclosed for high-sensitivity single molecule digital counting by the stochastic labeling of a collection of identical...
2016/0326583 System and Methods for Massively Parallel Analysis of Nucleic Acids in Single Cells
Methods and systems are provided for massively parallel genetic analysis of single cells in emulsion droplets or reaction containers. Genetic loci of interest...
2016/0326582 METHOD AND KIT FOR TARGET MOLECULE CHARACTERIZATION
Methods and kits for characterizing molecules, such as nucleic acids, large oligonucleotides, or portions thereof and/or to methods and kits for preparing...
2016/0326581 SINGLE MOLECULE ANALYSIS WITH HIGH ACCURACY
The invention relates to a process for analysing single molecules, in particular for sequencing of single nucleic acid molecules.
2016/0326580 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS
Methods and apparatus relating to very large scale FET arrays for analyte measurements. ChemFET (e.g., ISFET) arrays may be fabricated using conventional CMOS...
2016/0326579 Hydroxymethyl Linkers For Labeling Nucleotides
The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems...
2016/0326578 COMPOSITIONS AND METHODS FOR ACCURATELY IDENTIFYING MUTATIONS
The present disclosure provides compositions and methods for accurately detecting mutations by uniquely tagging double stranded nucleic acid molecules with...
2016/0326577 METHOD FOR TESTING A MUTANT GENE THROUGH REAL TIME POLYMERASE CHAIN REACTION USING INHIBITION OF 5'-FLAP...
The present invention relates to a method for detecting single nucleotide polymorphism (SNP) using a feature that the 5'-flap endonuclease (FEN) activity of...
2016/0326576 DUAL QUENCHER PROBES
The present invention provides nucleic acid probes comprising two quenchers of excited state energy, and methods of their use.
2016/0326575 METHOD FOR PRODUCING RNA
The present invention relates to a method for producing RNA. In particular, the present invention relates to a method for producing RNA, which is scalable and...
2016/0326574 METHODS TO ESTABLISH AND RESTORE NORMAL GUT MICROBIOTA FUNCTION OF SUBJECT IN NEED THEREOF
The present invention provides a method to define normal maturation of the gut microbiota using a limited number of bacterial taxa found in the gut microbiota....
2016/0326573 PROCESSING CONTAINERS
Processing containers include a first member having a substantially rigid body with a plurality of regions defining spaced apart workstations and a flexible...
2016/0326572 SYSTEMS AND METHODS FOR UNIVERSAL TAIL-BASED INDEXING STRATEGIES FOR AMPLICON SEQUENCING
Some embodiments of the invention include a method of preparing a sample for sequencing that includes receiving a sample and amplifying at least one marker...
2016/0326571 METHODS FOR NUCLEIC ACID AMPLIFICATION
The present disclosure provides novel methods for direct sample nucleic acid amplification with optional detection. The methods of the present disclosure...
2016/0326570 STABILIZED FORMULATION FOR LUMINESCENT DETECTION OF LUCIFERASE AND NUCLEOSIDE PHOSPHATES
Methods, kits and compositions containing a mixture of D-luciferin and L-luciferin for light generation with luciferase are disclosed that have improved...
2016/0326569 METHOD FOR ASSAYING A PROTEASE
A method of determining generation of an activated protease in a biological sample is provided. The method comprises the steps of exposing a biological sample...
2016/0326568 MEANS AND METHODS FOR UNIVERSAL CALIBRATION OF ANTI-FACTOR Xa TESTS
The present invention concerns diagnostic methods for coagulation testing involving determining anticoagulant activity elicited by a first anticoagulant in a...
2016/0326567 STABLE NAD/NADH DERIVATIVES
The present invention provides for stable nicotinamide adenine dinucleotide (NAD/NADH) and nicotinamide adenine dinucleotide phosphate (NADP/NADPH) derivatives...
2016/0326566 5-ALA FOR DETECTION OF BRAIN TUMORS
The present disclosure relates to methods for detecting brain tumors and assessing the recurrence of such tumors by administering a pharmaceutical composition...
2016/0326565 METHODS OF DETECTING AND QUANTIFIYING BACTERIA CONTAINED ON OR WITHIN CHEWING GUM
The invention provides for methods of extracting and quantitating the number of microorganisms contained on or within in chewing gum.
2016/0326564 METHOD FOR DETECTING, IDENTIFYING AND ENUMERATING MICRO-ORGANISMS IN A POROUS SUPPORT DRY-IMPREGNATED WITH A...
A method for the detection, identification and enumeration of microorganisms in a porous support including reaction medium powder throughout its thickness, the...
2016/0326563 RECOMBINANT N-GLYCOSYLATED PROTEINS FROM PROCARYOTIC CELLS
The present invention relates to recombinant N-glycosylated proteins, comprising one or more introduced N-glycosylated optimized amino acid sequence(s),...
2016/0326562 IMPROVED RECOMBINANT POLYPEPTIDE PRODUCTION METHODS
Herein is reported a method for producing a fusion-polypeptide comprising the steps of a) cultivating a mammalian cell comprising a nucleic acid encoding a...
2016/0326561 SEMI-CONTINUOUS PROCESS FOR THE PRODUCTION OF RHAMNOLIPIDS AT HIGH YIELD AND TITER
Provided is a semi-continuous fermentation method of a rhamnolipid producing microorganism to produce rhamnolipids. The fermentation may be run as a batch...
2016/0326560 HETEROLOGOUS EXPRESSION OF FUNGAL CELLOBIOHYDROLASES IN YEAST
The present invention provides for heterologous expression of polypeptides encoded by wild-type and condon-optimized variants of cbh1 and/or cbh2 from the...
2016/0326559 METHOD OF PRODUCING SUGAR LIQUID
A method of producing a sugar liquid from cellulose-containing biomass includes step (1) of hydrolyzing cellulose-containing biomass by a filamentous...
2016/0326558 Process for Stimulating Hyaluronic Acid Production with Ascorbic Acid Derivatives and the Composition Thereof
This invention discloses a process and composition for stimulating the production of hyaluronic acid. The mentioned process comprises reacting fibroblast cell...
2016/0326557 Biosynthesis of Forskolin and Related Compounds
The invention described materials and methods for producing oxidised 13R-MO, such as forskolin. In particular, the invention describes P450s involved in...
2016/0326556 RECOMBINANT STRAIN PRODUCING L-AMINO ACIDS, CONSTRUCTING METHOD THEREFOR AND METHOD FOR PRODUCING L-AMINO ACIDS
The present application discloses recombinant bacteria producing L-amino acid(s) its construction method and the method of producing L-amino acid(s). The...
2016/0326555 ENZYMATIC METHOD
The present invention relates to a method comprising the method steps A) Providing at least one compound of the general formula I) where X=divalent organic...
2016/0326554 RECOMBINANT MICROORGANISMS FOR PRODUCING ORGANIC ACIDS
Recombinant microorganisms that co express enzymatic glucose-6-phosphate dehydrogenase and malate dehydrogenase are generated to produce organic acids.
2016/0326553 METHODS AND ORGANISMS WITH INCREASED CARBON FLUX EFFICIENCIES
The invention is directed to a non-naturally occurring microbial organism comprising a first attenuation of a succinyl-CoA synthetase or transferase and at...
2016/0326552 EXPRESSION OF A HAP TRANSCRIPTIONAL COMPLEX SUBUNIT
The invention relates, for example, to recombinant yeast cells for differential gene expression during the propagation and production phases of a...
2016/0326551 ISOBUTANOL TOLERANCE IN YEAST WITH AN ALTERED LIPID PROFILE
Provided herein are recombinant yeast host cells and methods for their use for production of fermentation products from an engineered pyruvate utilizing...
2016/0326550 LACTIC ACID BACTERIA FOR THE PRODUCTION OF ETHANOL FROM BIOMASS MATERIAL
Lactic acid bacterial cultures, cell populations and articles of manufacture comprising same are disclosed for generating ethanol from lignocellulose.
2016/0326549 ALKENE PRODUCTION
The present invention provides a microbial cell capable of producing at least one terminal alkene from at least one short chain fatty acid, wherein the cell is...
2016/0326548 METHODS AND COMPOSITIONS FOR INCREASING TRANSGENE ACTIVITY
Methods and compositions for increasing transgene expression and/or activity, including for increasing nuclease-mediated genomic modifications.
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