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Patent # Description
2016/0326247 BIOLOGICAL PRODUCTS
There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human CD22. There is also...
2016/0326246 Method for Regulating Cell Proliferation
The present invention provides a composition for regulating cell proliferation comprising a peptide having a partial amino acid sequence of BBF2H7 or an...
2016/0326245 FRIZZLED RECEPTOR ANTIBODIES FOR TREATMENT OF CANCER
The invention provides antibodies or an antigen-binding portion thereof, which recognize the human Frizzled 7 receptor. Further, the invention provides methods...
2016/0326244 METHODS AND COMPOSITIONS FOR DIAGNOSIS AND TREATMENT OF DISORDERS IN PATIENTS WITH ELEVATED LEVELS OF CXCL9 AND...
Methods and compositions for treating hemophagocytic lymphohistiocytosis (HLH) are provided. The disclosure also relates generally to methods and compositions...
2016/0326243 USE OF IL-1 BETA BINDING ANTIBODIES FOR TREATING PERIPHERAL ARTERIAL DISEASE
The present invention relates to a method for treating or alleviating the symptoms of peripheral arterial disease (PAD) in a subject, comprising administering...
2016/0326242 ALPHABODY LIBRARIES AND METHODS FOR PRODUCING THE SAME
The invention provides single-chain Alphabody library comprising at least 100 different-sequence single-chain Alphabody polypeptides, wherein said Alphabody...
2016/0326241 TNFA-IL-17 BISPECIFIC ANTIBODIES
Bispecific tetravalent antibodies against IL-17 and TNFa, useful in therapy, e.g. the treatment of rheumatoid arthritis and other autoimmune diseases and/or to...
2016/0326240 COMPOSITION AND METHOD FOR THE DIAGNOSIS AND TREATMENT OF DISEASES ASSOCIATED WITH NEURITE DEGENERATION
Provided herein are antibodies and methods of using the antibodies to treat and diagnose neurite degenerative diseases and disorders.
2016/0326239 NOVEL HUMAN GENES RELATING TO RESPIRATORY DISEASES AND OBESITY
This invention relates to isolated nucleic acids comprising genes of human chromosome 12q23-qter and the proteins encoded by these genes. Expression vectors...
2016/0326238 Abeta CONFORMER SELECTIVE ANTI-Abeta GLOBULOMER MONOCLONAL ANTIBODIES
The subject invention relates to monoclonal antibodies that may be used in the treatment and diagnosis of Alzheimer's Disease. In particular, the present...
2016/0326237 METHODS OF TREATMENT FOR GUILLAIN-BARRE SYNDROME
This invention relates generally to methods of treatment for Guillain-Barre' Syndrome (GBS) and, more specifically, to methods involving the inhibition of the...
2016/0326236 MYCOBACTERIAL ANTIGEN COMPOSITION
The present invention provides an antigenic composition for use as a mycobacterial vaccine, said composition comprising (i) a first mycobacterial antigenic...
2016/0326235 N ANTIBODY POSSESSING AN AFFINITY FOR EPITHELIAL SECRETORY AND NERVOUS TISSUE, AS WELL AS TUMOUR TISSUE DERIVED...
We disclose the use of bacterial antigens and obtained antibodies. The resulting antibodies can be used in the diagnosis of tumors by immunohistochemistry and...
2016/0326234 MONOCLONAL ANTIBODY COCKTAILS FOR TREATMENT OF EBOLA INFECTIONS
Antibody variants originating from the monoclonal antibody 13C6, and wherein the N-glycosylation site within the constant region of the heavy chain contains a...
2016/0326233 NEUTRALIZING HUMAN MONOCLONAL ANTIBODIES AGAINST HEPATITIS B VIRUS SURFACE ANTIGEN
The invention is in the field of medical treatment and prevention. The invention provides an antibody or a part thereof capable of specifically binding to the...
2016/0326232 Prostate Specific Membrane Antigen Binding Fibronectin Type III Domains
PSMA binding FN3 domains, their conjugates, isolated nucleotides encoding the molecules, vectors, host cells, and methods of making thereof are useful in the...
2016/0326231 INHIBITOR TARGETING SPECIFIC COMPLEMENT SYSTEM, AND PREPARATION METHOD AND USE THEREOF
An inhibitor targeting specific complement, the inhibitor targeting specific complement is a protein, the protein has a targeted inhibition function on the...
2016/0326230 HUMAN RELAXIN ANALOGUE, PHARMACEUTICAL COMPOSITION OF SAME, AND PHARMACEUTICAL APPLICATION OF SAME
Disclosed are a human relaxin analogue, a polynucleotide encoding the human relaxin analogue, a pharmaceutical composition comprising the human relaxin...
2016/0326229 INHIBITION OF IL-17 PRODUCTION
The invention concerns inhibition of the production of proinflammatory cytokine interleukin-17 (IL-17) by T cells, using an antagonist of interleukin-23...
2016/0326228 ISOLATED NUCLEOTIDE SEQUENCES ENCODING GDF TRAPS
In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including...
2016/0326227 DIAGNOSTIC METHOD FOR DETECTING A GABA(A) RELATED AUTOIMMUNE DISEASE AND RELATED SUBJECT-MATTER
The present invention provides a use of a GABA(A)R, GABA(A)R fragment, or homolog thereof or a cell expressing the GABA(A)R, GABA(A)R fragment, or homolog...
2016/0326226 RETICULOCYTE GROWTH FACTOR AND PREPARING METHOD AND APPLICATION THEREOF
A Reticulocyte Growth Factor (RGF) and a preparing method and application thereof is provided. The factor is separated and purified from impurities of...
2016/0326225 ANTI-TUMOR PROPERTIES OF DICKKOPF 3b
The invention relates to novel therapeutic approaches to cancer treatment that exploits tumor suppressor functions of DKK3b by site-specific delivery of DKK3b....
2016/0326224 Polynucleotide For Cell Surface Layer Expression
Disclosed is a polynucleotide for cell surface expression. The polynucleotide of the invention comprises a promoter, a secretion signal sequence, a sequence...
2016/0326223 SIALIC ACID-SPECIFIC BINDING AFFINITY LECTIN FROM THE MUSHROOM HERICIUM ERINACEUM
The present invention concerns lectins isolated from the fruiting body of a novel Hericium erinaceum (deposit number: KCTC 12499BP) NEU-1L strain which bind...
2016/0326222 CLOSTRIDIUM DIFFICILE VACCINE
There are provided compositions and methods for prevention or treatment of Clostridium difficile infection. More specifically, there are provided Clostridium...
2016/0326221 STREPTOCOCCUS PYOGENES ANTIGENS AND CORRESPONDING DNA FRAGMENTS
The present invention relates to antigens more particularly antigens of Streptococcus pyogenes (also called group A Streptococcus (GAS)) bacterial pathogen...
2016/0326220 SECRETION AND FUNCTIONAL DISPLAY OF CHIMERIC POLYPEPTIDES
This disclosure relates to the display of proteins and peptides on cellular or non-biotic surfaces in the form of multivalent filamentous polymers. In...
2016/0326219 OPTICALLY ACTIVATED RECEPTORS
The present invention belongs to the field of biotechnology. More specifically, the invention relates to chimeric fusion proteins comprising a light activated...
2016/0326218 Analogue Peptide CMA3 Derived from CM-MA Peptide and Use Thereof
The present invention relates to a novel analogue antibiotic peptide derived from a CM-MA peptide and a use thereof. Specifically, the novel antibiotic...
2016/0326217 Methods and Compositions Related to Cyclic Peptide Synthesis
Disclosed are compositions and methods for cyclization of polymers such as peptides.
2016/0326216 HCV PROTEASE INHIBITORS AND USES THEREOF
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
2016/0326215 SELF-ASSEMBLED PEPTIDE NANOSTRUCTURES
Nanostructures made up from two or more types of short peptides (e.g., aromatic dipeptides), which differ from one another by the presence (or absence) of an...
2016/0326214 METHOD FOR THE PREPARATION OF BIOPOLYMERS
The present invention relates to a method of preparing and separating biopolymers and biopolymer fractions useful for wastewater treatment applications from...
2016/0326213 METHOD FOR CONTINUOUS PRODUCTION OF DEGRADATION PRODUCT OF WATER-INSOLUBLE POLYMERIC COMPOUND
This invention is intended to produce a novel functional material through solubilization and molecular weight reduction of a water-insoluble polymeric...
2016/0326212 Chemical Modification of Proteins
The invention relates to methods for selectively converting a cysteine residue in a peptide or protein to the dehydroalanine (Dha) residue. The method also...
2016/0326211 PROCESS FOR THE PRODUCTION OF 21-METHOXY-11-BETA-PHENYL-19-NOR-PREGNA-4,9-DIENE-3,20-DIONE DERIVATIVES
The present invention relates to a process for the synthesis of compounds of formula (I), ##STR00001## wherein the meaning of R is dimethylamino or acetyl group,...
2016/0326210 Enzymatic Process for Obtaining 17 Alpha-Monoesters of Cortexolone and/or its 9,11-Dehydroderivatives
The present invention refers to a new enzymatic process for obtaining 17.alpha.-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the...
2016/0326209 NOVEL 3-SUBSTITUTED 5-AMINO-6H-THIAZOLO[4,5-D]PYRIMIDINE-2, 7-DIONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS...
The present invention relates to compounds of formula (I), ##STR00001## wherein R.sup.1, R.sup.2 and R.sup.3 are as described herein, and their prodrugs or...
2016/0326208 5'-SUBSTITUTED NUCLEOSIDE COMPOUNDS
The present invention relates to novel 5'-substituted nucleoside compounds, pharmaceutical compositions comprising the compounds, and methods of using the...
2016/0326207 METHOD OF SUPPRESSING FORMATION OF PHOTOCROSSLINK, AND PHOTOREACTIVE NUCLEIC ACID IN WHICH AUTO-CROSSLINK...
Provided is a means for preventing the inactivation of a photoresponsive nucleic acid probe by suppressing the formation of a photocrosslink between a...
2016/0326206 NON-CALORIC SWEETENERS AND METHODS FOR SYNTHESIZING
Disclosed are steviol glycosides referred to as rebaudioside V and rebaudioside W. Also disclosed are methods for producing rebaudioside M (Reb M), rebausoside...
2016/0326205 INHIBITORS OF SODIUM GLUCOSE COTRANSPORTER 1
Inhibitors of sodium glucose cotransporter 1 (SGLT1), compositions comprising them, and methods of their use to treat diseases and disorders such as diabetes...
2016/0326204 PROCESS FOR PREPARING NON-PYROLYTIC BIO-OIL FROM LIGNOCELLULOSIC MATERIALS
The present invention refers to a process for catalytic fractionation of plant biomass, producing non-pyrolytic bio-oil from lignocellulosic materials in...
2016/0326203 Method for extracting lignin
The invention relates to a method for removing lignin from lignocellulosic biomass. The method comprises feeding of lignocellulosic biomass and a first aqueous...
2016/0326202 IRON(II) CATALYSTS CONTAINING TRIDENTATE PNP LIGANDS, THEIR SYNTHESIS, AND USE THEREOF
The application describes catalytic materials for hydrogenation or asymmetric hydrogenation. In particular, the application describes iron(ll) complexes...
2016/0326201 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF CANCERS
The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex...
2016/0326200 PRODRUG FOR RELEASE OF CISPLATIN AND CYCLOOXYGENASE INHIBITOR
Pt(IV) prodrugs include one or more conjugated cyclooxygenase inhibitor. Reduction of Pt(IV) to Pt(II) can result cisplatin and a cyclooxygenase inhibitor. For...
2016/0326199 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS
A process for the hydrogenation of a substrate comprising a carbon heteroatom double bond in the presence of a transition metal complex comprising a tridentate...
2016/0326198 RAW MATERIAL AND PRODUCTION METHOD FOR CYCLOMETALLIZED IRIDIUM COMPLEX
The present invention relates to a raw material for a cyclometalated iridium complex, and provides a technique that makes it possible to obtain a...
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