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Patent # Description
2016/0331804 SELECTIVELY TARGETED ANTIMICROBIAL PEPTIDES AND THE USE THEREOF
The present invention relates to targeting peptides capable of specifically binding to microbial organisms (e.g., P. aeruginosa or S. mutans), antimicrobial...
2016/0331803 VISTA ANTAGONIST AND METHODS OF USE
The present invention is directed to a peptide, multimer, conjugate, analog, derivative or mimetic thereof that inhibits the activity of VISTA. The invention...
2016/0331802 Pharmaceutical Compositions with Enhanced Stability
The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The...
2016/0331801 USE OF CASPASE-2 INHIBITORS TO TREAT AND PREVENT THE METABOLIC SYNDROME
Methods and compositions for treatment of obesity, insulin resistance, hyperinsulinemia, type 2 diabetes mellitus, dyslipidemia, and nonalcoholic fatty liver...
2016/0331800 BOTULINUM NEUROTOXIN-SPECIFIC CAPTURE AGENTS, COMPOSITIONS, AND METHODS OF USING AND MAKING
The present application provides stable peptide-based Botulinum neurotoxin (BoNT) serotype A capture agents and methods of use as detection and diagnosis...
2016/0331799 SG 20 minute burn magic formula
This is a formula in powder form, other burn remedies are a cream. Its use is for minor burns. Once the powder is applied to the wet skin it will draw the...
2016/0331798 NATURAL PRODUCT INHIBITORS OF 3DG
Compositions are disclosed which have as a component thereof an inhibitor of the enzymatic production of 3-deoxyglucosone (3DG) from fructoselysine and/or an...
2016/0331797 DERMATOLOGICAL COMPOSITION BASED ON ALGAE AND OLIVE LEAF EXTRACTS
The invention provides a dermatological composition comprising materials of algae origin (e.g. Arthrospira platensis) and olive leaf origin, the composition at...
2016/0331796 ENRICHED AMARANTHUS BLITOIDES COMPOSITIONS AND USES THEREOF
Embodiments of the inventions described herein provide, among other things, enriched Amaranthus blitoides compositions, such as those enriched with Vitamin D...
2016/0331795 COMPOSITION COMPRISING OKRA FOR USE IN REDUCING DIETARY FAT ABSORPTION
Composition comprising (optionally processed) edible parts of an okra plant species for use in reducing dietary fat absorption in a subject or for use in...
2016/0331794 COMPOSITION FOR USE IN THE TREATMENT OF PERSISTENT COUGH
The present application relates to a composition for the treatment of persistent cough, suitable also for pediatric use, processes for the preparation of said...
2016/0331793 ONCOLYTIC ADENOVIRUSES ARMED WITH HETEROLOGOUS GENES
The present disclosure relates to a group B adenovirus comprising a sequence of formula (I): 5'ITR-B1-BAB2-BX-BB-BY-B3-3'ITR wherein: B1 is bond or comprises:...
2016/0331792 METHODS FOR RESTORING MICROBIOTA OF NEWBORNS
The invention relates to methods and compositions for restoring normal microbiota in pre-term newborns or newborns delivered by Cesarean section and methods...
2016/0331791 Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Device for Delivering Them
This application provides compositions, e.g., formulations, used for gastric, gastrointestinal and/or colonic treatments, and methods for making, storing and...
2016/0331790 TREATING A BACTERIAL SKIN INFECTION WITH A WHOLE, LEECH SALIVA EXTRACT
Methods are also provided for isolating and using a whole-saliva leech extract in the treatment of a bacterial skin infection. The methods can include feeding...
2016/0331789 TREATING DAMAGED DERMAL OR MUCOSAL TISSUE WITH A WHOLE, LEECH SALIVA EXTRACT
Methods are provided for isolating and using a whole-saliva leech extract. The methods can include feeding a phagostimulatory agent to a leech; inducing a...
2016/0331788 SYSTEMS AND METHODS FOR THROMBOSIS PREVENTION
The disclosure provides a composition for inhibiting thrombosis. The composition includes 5 to 25% by weight of Fish Oil, 15 to 55% by weight of Willow Bark...
2016/0331787 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VITILIGO
Compositions and methods for darkening skin and treating vitiligo are provided.
2016/0331786 PLURIPOTENT STEM CELL-DERIVED OLIGODENDROCYTE PROGENITOR CELLS FOR THE TREATMENT OF SPINAL CORD INJURY
The present disclosure provides methods and compositions for making and using pluripotent stem cell-derived oligodendrocyte progenitor cells.
2016/0331785 Cells Treated by In Vitro Fucosylation and Methods of Production and Use Thereof
A population of cells possesses enhanced selectin binding based upon a fucosylated selectin ligand present on a surface thereof. Methods of producing the...
2016/0331784 COMPOSITIONS, METHODS, AND DEVICES FOR TREATING DISEASE
Described are compositions and methods for treating liver disease, e.g., acute liver disease, using bone marrow-derived stem cells and bone marrow-derived stem...
2016/0331783 BISAMIDE COMPOUNDS AS ALLOSTERIC EFFECTORS FOR REDUCING THE OXYGEN-BINDING AFFINITY OF HEMOGLOBIN
This invention relates to compounds of Formula (I) and pharmaceutically acceptable salts thereof, which are allosteric effectors that reduce the oxygen-binding...
2016/0331782 HETEROARYL DISULFIDE COMPOUNDS AS ALLOSTERIC EFFECTORS FOR INCREASING THE OXYGEN-BINDING AFFINITY OF HEMOGLOBIN
This invention relates to compounds of Formula I: (Formula I), and pharmaceutically acceptable salt thereof, which are allosteric effectors that increase the...
2016/0331781 ACTIVATION OF MARROW INFILTRATING LYMPHOCYTES IN HYPOXIC ALTERNATING WITH NORMOXIC CONDITIONS
Various embodiments of the invention relate to compositions comprising marrow infiltrating lymphocytes ("MILs"). The MILs may be activated MILs. Some...
2016/0331780 DECONTAMINANT EDIBLE PRODUCT, METHODS OF PRODUCTION AND USES THEREOF
The invention relates to an edible product containing a decontaminant. Particularly, the invention relates to an edible product, for instance, a food-like...
2016/0331779 METHOD OF INACTIVATING TOXINS USING OXIDATIVE CHLORINE SPECIES
Toxins produced by bacteria promote infection and disease by directly damaging host tissues and by disabling the immune system. In one embodiment, the present...
2016/0331778 FORMULATION OF LIPOSOME REHYDRATION SALTS
A liposomal rehydration salt formulation comprising phosphatidylcholine liposomes, salts, water, and a percentage inclusion ratio of salts (salts retained...
2016/0331777 USE OF ALGINATE OLIGOMERS AS BLOOD ANTICOAGULANTS
The disclosure relates to an alginate oligomer of 2 to 75 monomer residues, wherein said monomer residues do not carry a sulphate group, for use as a blood...
2016/0331776 COMPOSITION EFFECTIVE AGAINST VIRAL CONJUNCTIVITIS
The present invention relates to a pharmaceutical composition for use as a medicament in the prophylactic or therapeutic topical treatment of viral eye...
2016/0331775 E-SELECTIN INHIBITION WORKS IN COMBINATION WITH LOW-MOLECULAR WEIGHT HEPARIN TO DECREASE VENOUS THROMBOSIS AND...
The present disclosure provides compositions and methods for treating and preventing thrombosis. In particular, the present disclosure provides methods and...
2016/0331774 IMMUNOMODULATING COMPOSITIONS AND METHODS OF USE THEREOF
This invention is directed to .beta.-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The...
2016/0331773 ZIDOVUDINE COMBINATION THERAPIES FOR TREATING MICROBIAL INFECTIONS
The present invention relates to the use of a combination of an anti-retroviral agent such as zidovudine and anti-microbial agents for killing clinically...
2016/0331772 Composition Comprising a Uridine Source, an Omega-3 PUFA for Improving Coordination, Balance, Grip Strength or...
Composition comprising a uridine source, an omega-3 PUFA for improving coordination, balance, grip strength or fine motor skills. The invention is directed to...
2016/0331771 Treatment of Hyperproliferative Disorders Using Cardiac Glycosides
Provided are methods and compositions for treating and preventing hyperproliferative disorders such as psoriasis by administration of a cardiac glycoside alone...
2016/0331770 SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF
Disclosed herein are nucleosides, nucleotides and analogs thereof, pharmaceutical compositions that include one or more of nucleosides, nucleotides and analogs...
2016/0331769 GLUT4 ENDOCYTOSIS INHIBITOR
The present invention provides a therapeutic drug for diabetes containing 1,2-dioleoyl-sn-glycerol-3-phosphoethanolamine (DOPE) as an active ingredient,...
2016/0331768 COMPOSITIONS FOR ORAL ADMINISTRATION OF ZOLEDRONIC ACID OR RELATED COMPOUNDS FOR TREATING LOW BACK PAIN
Oral dosage forms of bisphosphonate compounds, such as zoledronic acid, can be used to treat or alleviate pain or related conditions. The oral bioavailability...
2016/0331767 Osteoclast inhibitors for bone marrow lesions
Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, can be used to treat or alleviate pain or related conditions.
2016/0331766 Osteoclast Inhibitors for Joint Conditions
Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, can be used to treat or alleviate pain or related conditions.
2016/0331765 METHOD OF TREATING AND PREVENTING SECONDARY HYPERPARATHYROIDISM
The method of treating elevated blood levels of iPTH by increasing or maintaining blood concentrations of both 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D...
2016/0331764 COMPOSITION COMPRISING XYLITOL AND CHOLECALCIFEROL FOR TOPICAL TREATMENT OF SKIN AND MUCOUS MEMBRANES
A composition for delivering cholecalciferol to skin and/or mucous membranes via topical application. The composition comprises xylitol and cholecalciferol in...
2016/0331763 COMPLEXES OF ABIRATERONE ACETATE, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS...
The present disclosure relates to pharmaceutically acceptable complex formulae comprising complexes of Abiraterone acetate and pharmaceutically acceptable...
2016/0331762 TRANSDERMAL TESTOSTERONE DEVICE AND DELIVERY
Described are transdermal drug delivery systems for the transdermal administration of testosterone, comprising a polymer matrix and testosterone. Methods of...
2016/0331761 METHODS AND COMPOSITIONS FOR TREATING RAYNAUD'S DISEASE
In various embodiments, methods and compositions for treating Raynaud's disease and Raynaud's phenomenon are provided. Topical administration of a semisolid...
2016/0331760 INCREASING STORAGE OF VITAMIN A, VITAMIN D AND/OR LIPIDS
The present disclosure provides compositions that include a nanoparticle and a compound that reduces the biological activity of one or more bromodomain and...
2016/0331759 Medicinal Composition for Treating Symptoms Related to Parkinson's Disease
A medicinal composition is administered orally twice a day to a patient to ameliorate the symptoms related to Parkinson's disease. The medicinal composition...
2016/0331758 TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND THEIR USE
The present invention is directed generally to stable formulations of a TLR agonist preferably a TLR7 or a TLR8 agonist, for use in the treatment of cancer,...
2016/0331757 FUSED IMIDAZOLE COMPOUNDS
The present invention provides compounds represented by formula (I), pharmaceutically acceptable salts thereof, N-oxides thereof, solvates thereof or prodrugs...
2016/0331756 HETEROCYCLIC COMPOUNDS USEFUL AS PDK1 INHIBITORS
The present invention provides compounds useful as inhibitors of PDK1. The present invention also provides compositions thereof, and methods of treating...
2016/0331755 Pharmaceutical Combinations
A pharmaceutical combination comprising: (a) a phosphatidylinositol-3-kinase inhibitor selected from ...
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