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Patent # Description
2016/0333404 METHODS FOR TREATING HCV
The present invention features therapies for the treatment of HCV comprising direct-acting antiviral agents. Preferably, the treatment is administered to an...
2016/0333403 NUCLEIC ACID CONSTRUCTS AND METHODS OF USE
The present invention provides oligonucleotide constructs, sets of such oligonucleotide constructs, and methods of using such oligonucleotide constructs to...
2016/0333402 BARCODE SEQUENCES, AND RELATED SYSTEMS AND METHODS
Methods, system, and kits are provided for sample identification, and, more specifically, for designing, and/or making, and/or using sample discriminating...
2016/0333401 Computational Methods for Translating a Sequence of Multi-Base Color Calls to a Sequence of Bases
Disclosed are systems and methods for resequencing using color calls. A DNA sample is encoded and sequenced according to a multi-base code producing a string...
2016/0333400 BIOMOLECULE ANALYSIS KIT AND BIOMOLECULE ANALYSIS METHOD
A biomolecule analysis kit includes a reaction container configured to perform an enzymatic reaction, the reaction container including a base portion which has...
2016/0333399 MICROPARTICLE CONTAINING NUCLEIC ACID CAPTURE PROBES AND METHOD OF USE
A method of identifying alleles of polymorphic sites in a plurality of nucleic acid samples including the steps of determining a source tag sharing number "d"...
2016/0333398 NUCLEIC ACID DETECTION AND QUANTIFICATION BY POST-HYBRIDIZATION LABELING AND UNIVERSAL ENCODING
The present invention provides, among other things, methods and compositions for encoding a substrate for detecting and quantifying target nucleic acids.
2016/0333397 METHOD AND DEVICE FOR ANALYZING REACTION LIQUID AFTER NUCLEIC ACID AMPLIFICATION REACTION, AND DEVICE FOR...
A reaction liquid after a nucleic acid amplification reaction is made suitable for various processes. A step of measuring the amount of a target product and the...
2016/0333396 COMPOSITIONS AND METHODS FOR DETERMINATION OF NUCLEIC ACID AMPLIFICATION STATUS AND KIT FOR PERFORMING SUCH METHODS
Compositions, methods and kits for determination of the nucleic acid amplification status of nucleic acid samples, and analysis of other high copy nucleic acid...
2016/0333395 METHODS AND MATERIALS FOR DETECTING VIRAL OR MICROBIAL INFECTIONS
This document provides methods and materials for detecting target nucleic acid. For example, methods and materials for detecting the presence or absence of...
2016/0333394 METHODS AND COMPOSITIONS FOR PREPARING RNA FROM A FIXED SAMPLE
The present invention provides improved methods and compositions for RNA isolation. In particular embodiments the present invention concerns the use of methods...
2016/0333393 METHOD AND MATERIALS TO DEPLETE IMPURITIES FOR EXTRACTION AND PURIFICATION OF NUCLEIC ACIDS FROM STOOL
Provided herein is materials and method relating to nucleic acids extraction and purification from biological samples such as stool. In particular, binding...
2016/0333392 NON-FOULING POLYMERIC SURFACE MODIFICATION AND SIGNAL AMPLIFICATION METHOD FOR BIOMOLECULAR DETECTION
An article such as a biosensor having a nonfouling surface thereon is described. The article comprises: (a) a substrate having a surface portion; (b) a linking...
2016/0333391 METHODS OF PRODUCING STERILIZED DIAGNOSTIC TEST ELEMENTS
In one non-limiting aspect, sterilizable reagent materials for diagnostic elements are provided. In other aspects, sterilized elements and techniques for...
2016/0333390 LOW COST GLUCOSE MONITORING SYSTEM AND METHOD OF USE
An improved system for monitoring blood glucose, especially in remote regions, is provided. The system includes a substrate comprising a sample umbra and a...
2016/0333389 NUCLEASE PROFILING SYSTEM
Some aspects of this disclosure provide strategies, methods, and reagents for determining nuclease target site preferences and specificity of site-specific...
2016/0333388 MASS SPECTROMETRIC RESISTANCE DETERMINATION BY MEASURING METABOLISM
The invention relates to a mass spectrometric method to determine microbial resistances to antibiotics. The decrease or modification of specific nutrient...
2016/0333387 Monitoring Microbial Growth Rates
Systems and methods of monitoring microbial growth rates are provided. In particular, a sensing electrode having a working electrode and a counter electrode...
2016/0333386 USE OF PEPTIDYLGLYCINE ALPHA-AMIDATING MONOOXIGENASE (PAM) FOR C-TERMINAL AMIDATION
One aspect as reported herein is a method for in vivo C-terminal amidation of a polypeptide characterized in that both the polypeptide (to be amidated) and...
2016/0333385 REGULATING ORINTHINE METABOLISM TO MANIPULATE THE HIGH MANNOSE GLYCOFORM CONTENT OF RECOMBINANT PROTEINS
The present invention relates to a method for manipulating the high mannose glycoform content of recombinant glycoproteins by regulating ornithine metabolism...
2016/0333384 CARBOHYDRATE-ENRICHED RECOMBINANT MICROORGANISMS
The present disclosure relates to recombinant microorganisms engineered for enhanced production of a desired carbohydrate, as well as related biomass, and...
2016/0333383 Method for Preparing Yeast Beta-D-Glucan Using Solubilization Technology Based on Molecular Assembly
The present invention provides a method for preparing yeast beta-D-glucan using a solubilization technology based on molecular assembly, comprising the...
2016/0333382 Process for Production of Soluble Sugars from Biomass
The present invention provides a process for enzyme mediated hydrolysis of biomass for production of soluble sugars, wherein the said process comprises of...
2016/0333381 TRANSAMINASE REACTIONS
The present disclosure relates to methods of using transaminase polypeptides in the synthesis of chiral amines from prochiral ketones.
2016/0333380 YEAST CELL HAVING ACID TOLERANCE, METHOD OF PREPARING YEAST CELL AND USE THEREOF
Provided are a genetically engineered yeast cell having increased activity of SUL1, STR3, HXT7, ERR1, GRX8, MXR1, GRE1, MRK1, AAD10 or a combination thereof,...
2016/0333379 METHOD AND SYSTEM FOR ELECTRO-ASSISTED HYDROGEN PRODUCTION FROM ORGANIC MATERIAL
A method for producing hydrogen from organic material. Organic material and hydrogen-producing microorganisms are provided in a completely mixed bioreactor for...
2016/0333378 METHODS AND PRODUCTS FOR TRANSFECTING CELLS
The present invention relates in part to nucleic acids encoding proteins, nucleic acids containing non-canonical nucleotides, therapeutics comprising nucleic...
2016/0333377 ENHANCING ENDONUCLEASE BASED GENE EDITING IN PRIMARY CELLS
Disclosed herein are nuclease-based systems for genome editing and methods of using the system for genome editing. Also, disclosed are approaches to enhance...
2016/0333376 RNA-Guided Gene Drives
RNA guided Cas9 gene drives and method for their use are disclosed.
2016/0333375 EXPRESSION IN INSECT CELLS OF GENES WITH OVERLAPPING OPEN READING FRAMES, METHODS AND COMPOSITIONS THEREFOR
The present teachings disclose nucleic acid cassettes for expressing in an insect cell a plurality of polypeptides encoded by a gene comprising overlapping...
2016/0333374 PSEUDOTYPED LENTIVIRAL VECTORS
The present invention relates to a nucleic acid molecule comprising or consisting of a nucleic acid sequence encoding the vesicular stomatitis virus envelope...
2016/0333373 Viral Vector Production System
The present invention relates to a nucleic acid sequence comprising a binding site operably linked to a nucleotide of interest, wherein the binding site is...
2016/0333372 CAPSID-MODIFIED, RAAV3 VECTOR COMPOSITIONS AND USES IN GENE THERAPY OF HUMAN LIVER CANCER
Disclosed are next-generation multi-mutated capsid protein-modified rAAV expression vectors, as well as infectious virions, compositions, and pharmaceutical...
2016/0333371 DNA ELEMENT HAVING THE ACTIVITY OF ENHANCING FOREIGN GENE EXPRESSION
Disclosed is a method for stably achieving high expression of a foreign gene in mammalian cells using a novel DNA element. More specifically disclosed is a DNA...
2016/0333370 Phytophthora Resistant Plants Belonging to the Solanaceae Family
Provided herein is a plant belonging to the Solanaceae family wherein said plant includes a genetic trait providing Phytophthora resistance and wherein said...
2016/0333369 YIELD IMPROVEMENT IN PLANTS
Polynucleotides and polypeptides incorporated into expression vectors are introduced into plants and were ectopically expressed. These polypeptides may confer...
2016/0333368 PLANTS WITH INCREASED FRUIT SIZE
The present invention relates to the field of transgenic and non-transgenic plants with novel phenotypes. Provided are Solanum lycopersicum Auxin Response...
2016/0333367 METHOD FOR IMPROVING STEM VOLUME GROWTH AND BIOMASS PRODUCTION IN TREES
The present invention relates to a genetic construct comprising a nucleic acid sequence encoding cytokinin biosynthetic isopentenyl-transferase enzyme (IPT)...
2016/0333366 Nucleotide Sequence Encoding Homeobox-Leucine Zipper Protein HAT22 (HD-ZIP Protein 22) From Corchorus Olitorius...
The present invention relates to the isolated polynucleotide encoding homeobox-leucine zipper protein HAT22 (HD-ZIP protein 22) from the plants Corchorus...
2016/0333365 METHOD OF PURIFYING MONOCLONAL ANTIBODIES
A new platform method to purify plant-based monoclonal antibodies is provided. Such a method includes an antibody purification platform that involves a...
2016/0333364 Saccharide-Modified Nucleic Acid Molecules
The present invention refers to the transfection of cells using a conjugate comprising at least one saccharide residue at least one nucleosidic component...
2016/0333363 Method, Vectors, Cells, Seeds and Kits for Stacking Genes into a Single Genomic Site
Methods of gene stacking are described herein. The methods can be used to repeatedly add genes into a chosen locus in a precise manner, which ensures...
2016/0333362 RECOMBINANT YEAST HAVING INCREASED TOLERANCE TO IONIC LIQUIDS AND METHODS OF USE
The present invention relates to materials and methods for the production of ethanol. More particularly, the present invention provides genetically modified...
2016/0333361 DNA VECTOR PRODUCTION SYSTEM
A vector production system is provided. The system comprises recombinant cells designed to encode at least a first recombinase under the control of an...
2016/0333360 SYSTEMS AND METHODS FOR THE SECRETION OF RECOMBINANT PROTEINS IN GRAM NEGATIVE BACTERIA
Disclosed herein are systems and methods for producing recombinant proteins utilizing mutant E. coli strains containing expression vectors carrying nucleic...
2016/0333359 MICROORGANISM INCLUDING GENE ENCODING PROTEIN HAVING HYDROXYLASE ACTIVITY AND METHOD OF REDUCING CONCENTRATION...
A microorganism including a foreign gene encoding a protein having a hydroxylase activity that reduces the concentration of CH.sub.nF.sub.4-n (n is an integer...
2016/0333358 A MODIFIED MICROORGANISM HAVING ENHANCED BIOMASS SYNTHESIS CAPACITY AND A METHOD THEREOF
The present disclosure provides a modified microorganism having an enhanced biomass synthesis capacity. The present disclosure also relates to a method for...
2016/0333357 METHODS FOR DELIVERY OF siRNA TO THE SPINAL CORD AND THERAPIES ARISING THEREFROM
The present application relates at least in part to methods for the administration of small interfering RNAs (siRNAs) to the spinal cord of a human or animal...
2016/0333356 OLIGONUCLEOTIDE MODULATORS OF THE TOLL-LIKE RECEPTOR PATHWAY
Disclosed herein are double stranded nucleic acid molecules and pharmaceutical compositions comprising same useful in the treatment of, inter alia, acute and...
2016/0333355 ANTI-TUMOR THERAPY
Compositions, kits and methods for treating cancer in a subject in need thereof are disclosed involving one or more genes the suppression of which renders the...
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