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Patent # Description
2016/0340333 PROCESS FOR PREPARATION OF ALOGLIPTIN
Provided is a novel process for the preparation of alogliptin.
2016/0340332 Compositions Comprising TPGS-750-M
In one embodiment, the present application discloses mixtures comprising (a) water in an amount of at least 1% wt/wt of the mixture; (b) a transition metal...
2016/0340331 NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS...
A compound inhibiting Hsp90 and a pharmaceutical composition including the same as an active ingredient are described, which compound is represented by formula...
2016/0340330 NO-RELEASING NITROOXY-CHROMENE CONJUGATES
The present invention provides NO-releasing nitrooxy-alkylenyl-linked-chromene conjugates, having the structure of Formula (1) wherein R1, R2, R3, R4, X, and L...
2016/0340329 FUNCTIONALISED BENZOPYRAN COMPOUNDS AND USE THEREOF
The present invention relates broadly to anti-cancer agents. In particular, the present invention relates to selected benzopyran compounds, the preparation...
2016/0340328 HYDROXY FORMAMIDE DERIVATIVES AND THEIR USE
Disclosed are compounds having the formula: ##STR00001## wherein R1, R2 and R3 are as defined herein, and methods of making and using the same, including use as...
2016/0340327 PROCESS FOR PREPARING AMORPHOUS CABAZITAXEL
The present invention provides a process for preparing amorphous Cabazitaxel from the solvate form of Cabazitaxel. The present invention also provides novel...
2016/0340326 Tizoxanide Carbamate and Pharmaceutical Use Thereof
The invention relates to a tizoxanide carbamate compound of Formula I and a pharmaceutically acceptable salt, a hydrate or a solvate thereof, and their...
2016/0340325 SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF
The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the...
2016/0340324 METHODS AND COMPOSITIONS FOR TREATING CANCER
Embodiments provided herein relate to methods and compositions for treating cancer. Some embodiments relate to certain compounds having activity against...
2016/0340323 AZAQUINAZOLINE CARBOXAMIDE DERIVATIVES
Novel azaquinazoline carboxamide derivatives of formula (I) ##STR00001## wherein W.sup.1, W.sup.2, W.sup.3, W.sup.4, R.sup.1, R.sup.2, R.sup.3 and m which are...
2016/0340322 SUBSTITUTED TRIAZINONE COMPOUND AND T-TYPE CALCIUM CHANNEL INHIBITOR
Disclosed is a novel triazinone compound with an inhibitory activity on a T-type voltage-dependent calcium channel, and is specifically useful for prevention...
2016/0340321 Substituted 1,2,3-Triazoles as Antitumor Agents
Compounds represented by Formula I: ##STR00001## and/or a pharmaceutically acceptable salts, a prodrug, a solvate and a combination thereof, a pharmaceutical...
2016/0340320 S-SUBSTITUTED QUINAZOLINES AND THEIR THERAPEUTIC APPLICATIONS FOR THE TREATMENT OF DISEASES MEDIATED BY PDE7
The present invention relates to a family of S-substituted quinazoline derivatives that inhibitors of the enzyme phosphodiesterase 7 (PDE7), useful for the...
2016/0340319 SUBSTITUTED BICYCLIC DIHYDROPYRIMIDINONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY
This invention relates to substituted bicyclic dihydropyrimidinones of formula 1 ##STR00001## and their use as inhibitors of neutrophil elastase activity, ...
2016/0340318 2,5-DIOXOIMIDAZOLIDIN-1-YL-3-UREA DERIVATIVES AS FORMYL PEPTIDE MODULATORS
The present invention relates to 1-(2,5-dioxoimidazolidin-1-y)-3-substituted urea compounds, processes for preparing them, pharmaceutical compositions...
2016/0340317 COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS
The present invention relates to compounds of Formula I, ##STR00001## a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate...
2016/0340316 RING-CONTRACTED MORPHINANS AND THE USE THEREOF
The application is directed to compounds of Formula (I) or (IA) and pharmaceutically acceptable salts and solvates thereof, wherein R.sup.1 R.sup.2, .sup.R3...
2016/0340315 FACTOR XIa INHIBITORS
The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said...
2016/0340314 QUINOLONE COMPOUND
The present invention provides a compound represented by the formula (I) ##STR00001## wherein X is a hydrogen atom or a fluorine atom; R is a hydrogen atom or ...
2016/0340313 COMPOUNDS, COMPOSITIONS AND ASSOCIATED METHODS COMPRISING 3-ARYL QUINOLINES
Compounds, compositions and methods useful for treating infectious diseases are provided. In particular, 3-aryl quinoline compounds, their synthesis,...
2016/0340312 Novel Substituted Quinoline Compounds as S-Nitrosoglutathione Reductase Inhibitors
The present invention is directed to novel quinoline compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions...
2016/0340311 RECOVERY AND/OR REUSE OF PALLADIUM CATALYST AFTER A SUZUKI COUPLING
Methods for the recovery and/or reuse of palladium catalyst after a Suzuki coupling reaction in which two molecules are coupled are described.
2016/0340310 Pyridine Derivatives
The present application provides novel pyridine compounds and pharmaceutically acceptable salts or prodrugs thereof. Also provided are methods for preparing...
2016/0340309 SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF
The invention provides compounds having activity as sodium channel (e.g., NaV1.7) inhibitors that are useful for treating sodium channel-mediated diseases or...
2016/0340308 TETRACYCLIC COMPOUND
A compound represented by the general Formula (I) below, or a salt or solvate thereof, which is useful as an ALK inhibitor, and is useful for prophylaxis or...
2016/0340307 METHODS OF MANUFACTURE OF 2-HYDROCARBYL-3,3-BIS(HYDROXYARYL)PHTHALIMIDINES
A method for the manufacture of a 2-hydrocarbyl-3,3-bis(hydroxyaryl)phthalimidine composition comprises: reacting a phthalimide of formula (2) with a phenol of...
2016/0340306 DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS
Disclosed herein are compositions and methods of treating osteroporosis, bone fracture, bone loss, and increasing bone density by administration of compounds...
2016/0340305 DIRECT STEREOSPECIFIC SYNTHESIS OF UNPROTECTED AZIRIDINES FROM OLEFINS
A method for the direct stereospecific conversion of structurally diverse mono-, di-, tri- and tetra-substituted olefins to N--H, N-alkyl, N-cycloalkyl, or...
2016/0340304 COUPLING OF TWO ARENES WITH SELENIUM DIOXIDE TO GIVE A SELENOBIARYL ETHER
Method for coupling two arenes with selenium dioxide to give a selenobiaryl ether, and also novel selenobiaryl ethers.
2016/0340303 Method for Synthesizing of Thioesters by Using Compound as Catalyst
A method for synthesizing of thioesters by using a compound as a catalyst is disclosed. The compound is represented by formula I below: ##STR00001## In formula...
2016/0340302 ETHOXYLATED SURFACTANTS
The present invention provides sulfur- or selenium-containing compounds comprising hydrophobic moieties and ethoxylated ester or ethoxylated amide moieties...
2016/0340301 CYCLIC PROCESS FOR PRODUCTION OF TAURINE FROM ALKALI VINYL SULFONATE
A cyclic process is disclosed for the production of taurine from alkali vinyl sulfonate in a high overall yield by continuously converting the byproducts of...
2016/0340300 PROCESS FOR PRODUCING TAURINE
There is disclosed a process for producing taurine by the ammonolysis of alkali isethionate in the presence of alkali ditaurinate or alkali tritaurinate, or...
2016/0340299 DIAMINOGUANIDINE DERIVATIVES AND APPLICATION THEREOF IN PREPARATION OF ANIMAL GROWTH PROMOTERS USED IN FEED
Diaminoguanidine derivatives in preparation of animal growth promoters used in feed. The diaminoguanidine derivatives have a structural formula as shown in...
2016/0340298 NOVEL COMPOUNDS
Disclosed are compounds of the general formula I and II (as further defined herein) are useful in the production of inhibitors of sphingolipid synthesis the...
2016/0340297 MULTIPLE CYCLOADDITION REACTIONS FOR LABELING OF MOLECULES
The present invention relates to methods for linking tetrazines with dienophiles to establish at least two linkages by sequentially performing at least two...
2016/0340296 MIXED METAL OXIDE CATALYSTS
Catalytic compositions are provided that are effective for providing increased acrylonitrile product without a significant decrease in hydrogen cyanide and/or...
2016/0340295 APPARATUS FOR PRODUCING MIXED SOLUTION AND METHOD FOR PREPARING MIXED SOLUTION
An apparatus for producing a mixed solution, comprising a mixing vessel for preparing an aqueous mixed solution containing a dicarboxylic acid and an Nb...
2016/0340294 FATTY ACID FUMARATE DERIVATIVES AND THEIR USES
The invention relates to Fatty Acid Fumarate Derivatives; compositions comprising an effective amount of a Fatty Acid Fumarate Derivative; and methods for...
2016/0340293 CATALYST COMPOSITION FOR POLYMERIZATION OF OLEFINS
A catalyst composition including the compound of Formula I as an internal electron donor, ##STR00001## wherein: R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and ...
2016/0340292 ODOUR-MASKED AMINE COMPOSITION
The present invention relates to a composition comprising: a) at least one primary, secondary or tertiary amine and b) at least one agent which masks the odour...
2016/0340291 NOVEL ORGANOLEPTIC COMPOUNDS
The present invention relates to novel compounds and their use as fragrance materials.
2016/0340290 POLYGLYCEROL ESTERS WITH A PARTICULAR OLIGOMER DISTRIBUTION OF THE POLYGLYCEROL
The invention relates to novel polyglycerol esters with a particular oligomer distribution of the polyglycerol present, and to their use in particular in...
2016/0340289 PROCESSES OF PREPARING ESTOLIDE COMPOUNDS THAT INCLUDE REMOVING SULFONATE RESIDUES
Provided herein are processes of preparing sulfonated estolide compounds, and the removal of sulfonate residues from those compounds to provide desulfonated...
2016/0340288 SMALL MOLECULE INHIBITORS OF TRPA1
The present invention relates to the use of compounds which are capable of attenuating skin irritation when they are applied to the skin. Skin irritation can...
2016/0340287 PROCESSES FOR OBTAINING MICROBIAL OIL FROM MICROBIAL CELLS
Disclosed are processes for obtaining a microbial oil comprising one or more polyunsaturated fatty acids (PUFAs) from one or more microbial cells by lysing the...
2016/0340286 CLOSTRUBINS
The present invention relates to a bioactive compound according to general formula (I); to a pharmaceutical composition comprising one or more of the...
2016/0340285 FLAVOR AND FRAGRANCE FORMULATION (VII)
The present invention relates to the use of a specific organic compound as flavor and fragrance material. Furthermore the invention relates to flavor and...
2016/0340284 Alpha,Alpha-Difluoroacetaldehyde Production Method
A production method of .alpha.,.alpha.-difluoroacetaldehyde according to the present invention includes reaction of an .alpha.,.alpha.-difluoroacetic acid...
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