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Patent # Description
2016/0340733 MULTIPLEXED PARALLEL ANALYSIS OF TARGETED GENOMIC REGIONS FOR NON-INVASIVE PRENATAL TESTING
The invention provides methods for non-invasive prenatal testing that allow for detecting risk of chromosomal and subchromosomal abnormalities, including but...
2016/0340732 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING NUCLEOTIDE REPEAT DISORDERS
The present application discloses compositions and methods useful for diagnosing and treating nucleotide repeat disorders. An in silico analysis indicates a...
2016/0340731 METHOD
A method of identifying a subject falling within a new patient population characterised by eosinophil IgE mediated allergic inflammation, involving analysing...
2016/0340730 METHODS FOR EVALUATING NEUROLOGICAL DISEASE
The present invention provides methods and systems for evaluating neurological disease in a patient. The neurological disease may be a demyelinating disease...
2016/0340729 METHODS FOR DEFINING AND PREDICTING IMMUNE RESPONSE TO ALLOGRAFT
Methods are provided for predicting and determining a subject's immune response to allograft. Methods include assessing immune response to an allograft by...
2016/0340728 SINGLE-CELL NUCLEIC ACID ANALYSIS
The present invention provides methods for analysis of genomic DNA and/or RNA from small samples or even single cells. Methods for analyzing genomic DNA can...
2016/0340727 FINE-TUNED ULTRASPECIFIC NUCLEIC ACID HYBRIDIZATION PROBES
Compositions and methods for highly specific nucleic acid probes and primers are provided. The probe system comprises a complement strand and a protector stand...
2016/0340726 Method and System for Multiplex Genetic Analysis
The present disclosure provides apparatus, systems and method for detecting separately and substantially simultaneously light emissions from a plurality of...
2016/0340725 METHOD TO INCREASE SENSITIVITY OF NEXT GENERATION SEQUENCING
A method for detecting a low-occurrence mutation in isolated DNA adds a blocking probe to reagents during amplification of the isolated DNA. The blocking probe...
2016/0340724 CONJUGATES OF NUCLEOTIDES AND METHODS FOR THEIR APPLICATION
Methods for enzymatic synthesis of nucleic acid chains are disclosed in which a nucleotide-macromolecular conjugate is incorporated into the complementary...
2016/0340723 Multiplexed Analysis Of Polymorphic Loci By Concurrent Interrogation And Enzyme-Mediated Detection
The invention provides methods and processes for the identification of polymorphisms at one ore more designated sites, without interference from non-designated...
2016/0340722 Methods And Systems For Detecting Genetic Mutations
Methods for detecting a genetic mutation in target nucleotide sequences by sorting the target nucleotide sequences into bins, aligning the target nucleotide...
2016/0340721 NANO-SENSOR ARRAY
In one embodiment, a method is provided for the manufacture of a nano-sensor array. A base having a sensing region is provided along with a plurality of...
2016/0340720 METHODS AND COMPOSITIONS FOR ARRAY-BASED COUNTING
Methods, kits, and systems are disclosed for array-based counting. The method generally comprises obtaining data pertaining to one or more probes on an array...
2016/0340719 SYSTEMS AND METHODS FOR CHARACTERIZING A MOLECULE
Techniques for characterizing a molecule are described herein. In one example, a portion of the molecule is trapped in a nanopore, a variable voltage is...
2016/0340718 DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES BY COMPARATIVE GENOMIC HYBRIDIZATION
The present invention provides a method of detecting nucleotide sequence differences between two nucleic acid samples. The method employs a comparative genomic...
2016/0340717 OLIGONUCLEOTIDE-BASED PROBES AND METHODS FOR DETECTION OF MICROBES
The present invention relates to a rapid detection of microbial-associated nuclease activity with chemically modified nuclease (e.g., endonuclease) substrates,...
2016/0340716 NON-THERMAL CYCLING FOR POLYMERASE CHAIN REACTION
Techniques, systems, and devices are disclosed for non-thermal cycling of polymerase chain reaction (PCR). In one aspect, a method for cycling PCR includes...
2016/0340715 End-Point Optical System and Method of Use
Systems and methods are used to detect spectral and spatial information in a continuous flow PCR system. An incident beam of electromagnetic radiation is...
2016/0340714 Methods And Compositions For Detecting Multiple Analytes With A Single Signal
Compositions, methods, and devices for the detection of multiple analytes with a single signal are provided.
2016/0340713 STABILIZING COMPOSITIONS AND METHODS FOR EXTRACTION OF RIBONUCLEIC ACID
The present invention provides a composition and method for stabilizing ribonucleic acid (RNA) from biological samples such that the ribonucleic acid within...
2016/0340712 CATION CHELATOR HOT START
The invention is in the field of regulation of enzymatic activity in nucleic acid modifying reactions. It describes a method of regulating enzymatic activity...
2016/0340711 DETECTING SINGLE NUCLEOTIDE POLYMORPHISM USING OVERLAPPING HYDROLYSIS PROBES
Methods for the rapid detection of the presence or absence of a SNP in a target nucleic acid in a sample are described. The methods can include performing an...
2016/0340710 Sequence conversion and signal amplifier DNA cascade reactions and detection methods using same
Disclosed are methods for detecting a target nucleic acid in a sample. The methods include contacting the sample, in the presence of a polymerase and an...
2016/0340709 FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF
Compounds are provided that are either fluorogenic or fluorophoric. Compositions and articles that include the compounds are also provided. Additionally,...
2016/0340708 MODIFIED ARSENITE OXIDASE AND A BIOSENSOR FOR DETECTING ARSENITE
The present invention provides an arsenite oxidase enzyme modified to prevent translocation by modification of a translocation signal sequence. A microorganism...
2016/0340707 GAMMA-GLUTAMYL-VALINE SYNTHASE, AND METHOD FOR PRODUCING GAMMA-GLUTAMYL-VALYL-GLYCINE
.gamma.-Glu-Val synthetase suitable for generating .gamma.-Glu-Val, and a method for producing .gamma.-Glu-Val-Gly using the same are provided. By using...
2016/0340706 Method for Optimizing Post-Translational Modifications on Recombinant Proteins
A method for optimizing post-translational modifications of recombinant proteins expressed in living cells is described. More particularly, a method for...
2016/0340705 Process for Fractionation of Oligosaccharides from Agri-Waste
The present invention provides a continuous and cost effective chemo-enzymatic process for fractionation of holocellulose, obtained from agri-waste, into...
2016/0340704 METHOD OF MAKING A BENZYLISOQUINOLINE ALKALOID (BIA) METABOLITE, ENZYMES THEREFORE
There is provided a method of preparing a benzylisoquinoline alkaloid (BIA) metabolite comprising: a. culturing a host cell under conditions suitable for...
2016/0340703 ASTRAGALUS MEMBRANACEUS FERMENTATION PRODUCT AND METHOD OF PRODUCING THE SAME
Provided are an astragalus membranaceus fermentation product and a method of producing the astragalus membranaceus fermentation product, in which a lactic acid...
2016/0340702 HEAT-STABLE, FE-DEPENDENT ALCOHOL DEHYDROGENASE FOR ALDEHYDE DETOXIFICATION
The present invention relates to microorganisms and polypeptides for detoxifying aldehydes associated with industrial fermentations. In particular, a...
2016/0340701 METHODS OF USING CAPSAICIN SYNTHASE FOR THE MICROBIAL PRODUCTION OF CAPSAICINOIDS
A biosynthetic method of making a capsaicinoid including expressing a first gene product of CS/AT3/Pun1 in a cellular system, growing the cellular system in a...
2016/0340700 MICROORGANISMS AND METHODS FOR THE PRODUCTION OF FATTY ACIDS AND FATTY ACID DERIVED PRODUCTS
This invention relates to metabolically engineered microorganism strains, such as bacterial strains, in which there is an increased utilization of malonyl-CoA...
2016/0340699 TYPE II FATTY ACID SYNTHESIS ENZYMES IN REVERSE -OXIDATION
This disclosure describes enzymes from the type II (a discrete set of enzymes) fatty acid synthesis ("FAS") pathway that can be used in combination with...
2016/0340698 GENETICALLY ENGINEERED YEAST CELL HAVING INCREASED NADPH PRODUCTION, METHOD OF INCREASING NADPH LEVEL IN YEAST...
Provided is a genetically engineered yeast cell having increased NADPH production, a method of increasing a NADPH level in a yeast cell, a method of preparing...
2016/0340697 Genetically Modified Yeast Species, and Fermentation Processes Using Genetically Modified Yeast
Yeast cells are transformed with an exogenous xylose isomerase gene. Additional genetic modifications enhance the ability of the transformed cells to ferment...
2016/0340696 VERSATILE EXTREMELY THERMOPHILIC BACTERIA FOR THE CONVERSION OF BIOMASS
Methods of producing ethanol by incubating lignocellulosic hydrolysates in the presence of cells of an isolated strain of Thermoanaerobactor at a temperature...
2016/0340695 METHOD OF PRODUCING ISOPRENE MONOMER
Isoprene synthase-expressing microorganisms that exhibit improved expression of pyrophosphate phosphatase are useful for producing isoprene monomer.
2016/0340694 METHODS AND COMPOSITIONS FOR PRODUCING OLEFINS
Compositions and methods for producing olefins are described herein. The olefins can be used to produced biofuels.
2016/0340693 Muscle-Specific Nucleic Acid Regulatory Elements and Methods and Use Thereof
The present invention relates to nucleic acid regulatory elements that are able to enhance muscle-specific expression of genes, in particular expression in...
2016/0340692 TARGETED GENE DELIVERY FOR DENDRITIC CELL VACCINATION
Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus...
2016/0340691 ENHANCED NUCLEIC ACID CONSTRUCTS FOR EUKARYOTIC GENE EXPRESSION
The present invention provides polynucleotide vectors for high expression of heterologous genes, and methods for constructing such vectors. Some vectors...
2016/0340690 NOV MINI-PROMOTERS
Isolated polynucleotides comprising a NOV mini-promoters are provided. The mini-promoter may be operably linked to an expressible sequence, including, but not...
2016/0340689 GLYPHOSATE-TOLERANT GENE AND USE THEREOF
Disclosed is a glyphosate-tolerant gene. The nucleotide sequence of the gene is SEQ ID NO: 1, SEQ ID NO: 3 or SEQ ID NO: 5, and a mutant form of the gene that...
2016/0340688 COMPOSITIONS AND METHODS FOR IMPROVING ABIOTIC STRESS TOLERANCE
The present invention relates to compositions and methods for improving the abiotic stress tolerance of plants. Plants and plant parts identified, selected...
2016/0340687 METHOD FOR PRODUCTION OF TRANSGENIC COTTON PLANTS
The present invention provides a method for producing transgenic Cotton plants. In one method transformed plants, that overexpress the transgene shows a...
2016/0340686 Improved Digestibility of Plant Biomass
Plants described herein have increased biomass and are more readily digested into fermentable sugars when the plants express increased levels of one or more...
2016/0340685 SORGHUM-DERIVED TRANSCRIPTION REGULATORY ELEMENTS PREDOMINANTLY ACTIVE IN ROOT HAIR CELLS AND USES THEREOF
Transcription regulatory elements, namely promoter and terminator sequences, obtained from Sorghum bicolor that drive RNA transcription predominately in root...
2016/0340684 DISCOVERY AND UTILIZATION OF SORGHUM GENES (MA5/MA6)
Methods and composition for the production of non-flowering or late flowering sorghum hybrid. For example, in certain aspects methods for use of molecular...
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