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Patent # Description
2016/0340683 NANOCARRIER BASED PLANT TRANSFECTION AND TRANSDUCTION
The present invention provides a novel method for the transduction and/or transfection of plant cells. Cell-penetrating peptides (CPPs) have been successfully...
2016/0340682 METHOD OF OBTAINING TRANSFORMED PLANT CELL
The present invention relates to a method of obtaining a transformed plant cell. The present invention comprises the steps of: (a) co-transforming an...
2016/0340681 Method for Producing an L-Amino Acid Using a Bacterium of the Family Enterobacteriaceae Having Overexpressed...
The present invention provides a method for producing L-amino acids or salts thereof by fermentation using a bacterium of the family Enterobacteriaceae,...
2016/0340680 MODULATION OF KCNH2 ISOFORM EXPRESSION BY OLIGONUCLEOTIDES AS A THERAPEUTIC APPROACH FOR LONG QT SYNDROME
Oligonucleotides with activity in preventing poly(A) adenylation at intron 9 of the KCNH2 gene, as well as pharmaceutical compositions comprising the...
2016/0340679 KETOHEXOKINASE (KHK) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
The present invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the ketohexokinase (KHK) gene, and methods of using such RNAi agents...
2016/0340678 TREATMENT OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE...
Oligonucleotide compounds modulate expression and/or function of Vascular Endothelial Growth Factor (VEGF) polynucleotides and encoded products thereof....
2016/0340677 ANTIVIRAL THERAPY
The present invention provides a method of identifying host cell molecules which may be modulated to inhibit viral replication and method of testing antiviral...
2016/0340676 METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA
The invention provides compositions and methods for selectively reducing the expression of a gene product from a desired target gene, as well as treating...
2016/0340675 MICRORNA MODULATION OF ARTHEROSCLEROSIS AND USES THEREOF
The presently disclosed subject matter provides anti-miRNAs for the treatment of diseases associated with atherogenesis and methods of treatment, and diagnosis...
2016/0340674 Compositions and Methods to Inhibit EZH2 for the Treatment of Cardiovascular Diseases
The present invention relates to compositions and methods for treatment and/or prevention of a cardiovascular disease. In one embodiment, the invention...
2016/0340673 METHODS FOR THE PREVENTION AND THE TREATMENT OF EXTRACAPILLARY GLOMERULONEPHRITIS
The present invention relates to the prevention and the treatment of extracapillary glomerulonephritis such as rapidly progressive glomerulonephritis and...
2016/0340672 DE NOVO SYNTHESIZED GENE LIBRARIES
De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building...
2016/0340671 Clonal Analysis of Functional Genomic Assays and Compositions for Practicing Same
Methods of clonal analysis of functional genomic assays are provided. Aspects of the invention include transducing a population of target cells with a packaged...
2016/0340670 NOVEL OLIGO-LINKER-MEDIATED DNA ASSEMBLY METHOD AND APPLICATIONS THEREOF
A method for generating a library of expression vectors comprising a plurality of donor sequences and a plurality of oligo-linker nucleic acids, termed...
2016/0340669 METHOD AND APPARATUS FOR ISOLATING NUCLEIC ACIDS
A method comprises: sorbing a sample solution comprising nucleic acids to a sample receiving portion of a quartz fiber filter by contacting the sample solution...
2016/0340668 SINGLE-STEP DNA PREPARATION FOR POLYMERASE CHAIN REACTION USING MAGNETIC CHITOSAN MICROPARTICLES
The present invention relates to a method for concentrating a biological sample containing nucleic acids by using magnetic chitosan microparticles and...
2016/0340667 IMMOBILIZED PROTEINS AND USE THEREOF
The invention relates to an immobilized protein material comprising a protein that is immobilized on a glass material or organic polymer through affmity tag...
2016/0340666 METHOD FOR THE BIOCATALYTIC CYCLIZATION OF TERPENES AND CYCLASE MUTANTS EMPLOYABLE THEREIN
The present invention relates to novel mutants with cyclase activity and use thereof in a method for biocatalytic cyclization of terpenes, such as in...
2016/0340665 Bacteria Engineered to Reduce Hyperphenylalaninemia
Genetically engineered bacteria, pharmaceutical compositions thereof, and methods of modulating and treating diseases associated with hyperphenylalaninemia are...
2016/0340664 COMPOSITIONS AND METHODS COMPRISING A XYLANASE ENZYME VARIANT
The present invention provides hemicellulytic enzyme variants. Specifically, the present invention provides xylanase variants having one or more modifications...
2016/0340663 THERMOSTABLE GLYCOSIDE HYDROLASE
A thermostable glycoside hydrolase having a glycoside hydrolase catalytic domain including: (A) a polypeptide including the amino acid sequence represented by...
2016/0340662 ENGINEERING OF SYSTEMS, METHODS AND OPTIMIZED GUIDE COMPOSITIONS FOR SEQUENCE MANIPULATION
The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and...
2016/0340661 DELIVERY, USE AND THERAPEUTIC APPLICATIONS OF THE CRISPR-CAS SYSTEMS AND COMPOSITIONS FOR GENOME EDITING
The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of...
2016/0340660 CRISPR-CAS SYSTEMS, CRYSTAL STRUCTURE AND USES THEREOF
The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are...
2016/0340659 ACTIN BINDING PEPTIDES AND COMPOSITIONS COMPRISING SAME FOR INHIBITING ANGIOGENESIS AND TREATING MEDICAL...
The present invention, in some embodiments thereof, relates to biologically active peptides and, more particularly, but not exclusively, to peptides from T2...
2016/0340658 PTERIS VITTATA PHYTASE NUCLEOTIDE AND AMINO ACID SEQUENCES AND METHODS OF USE
The present disclosure provides isolated and synthetic DNA and cDNA molecules encoding a phytase from the root of Pteris vittata (PV); root PV phytase proteins...
2016/0340657 Mutant Reverse Transcriptase and Methods of Use
The invention relates to the generation and characterization of stable MMLV reverse transcriptase mutants. The invention also discloses methods of using stable...
2016/0340656 PEPTIDES DERIVED FROM GSE 24.2 FOR TREATING DISEASES CAUSED BY OXIDATIVE STRESS AND DAMAGE TO DNA
This invention relates to a polypeptide which comprises the fragment SEQ ID No. 2 of peptide GSE24.2 (SEQ ID No. 1) and can reduce the production of free...
2016/0340655 ERK-DERIVED PEPTIDES AND USES THEREOF
An isolated peptide being no longer than 20 amino acids comprising a sequence at least 95% homologous to the sequence GQLNHILGILGX.sub.1PX.sub.2QED (SEQ ID NO:...
2016/0340654 PERMUTED AND NONPERMUTED LUCIFERASE BIOSENSORS
A modified luciferase protein which is a sensor for molecules including cAMP, cGMP, calcium, chelators thereof, kinases, or phosphatases is provided. Also...
2016/0340653 DELIVERY OF PACKAGED RNA TO MAMMALIAN CELLS
Described herein are compositions relating to alphavirus-based virus-like particles (VLPs) and methods for making and using the described VLPs. The described...
2016/0340652 CULTURE MEDIUM FOR STEM CELL DIFFERENTIATION
Media for the culture of pluripotent stem cells and differentiation of cardiomyocytes, and methods of using this media to produce cardiomyocytes. These media...
2016/0340651 METHODS FOR CULTURING DERMAL CELLS FOR TREATMENT OF SKIN INJURIES SUCH AS BURNS
The present invention relates to novel methods of growing or otherwise producing unpassaged or minimally passaged dermal cells from a small biopsy specimen for...
2016/0340650 BLOOD DERIVED IMMUNE STIMULATORY COMPOSITIONS
Neutrophil extracellular traps (NETS) are webs of DNA held together with immunogenic peptides, released by neutrophils subsequent to activation. NETS are the...
2016/0340649 Costimulatory Chimeric Antigen Receptor T Cells Targeting IL13Rx2
Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes IL-13 or a variant thereof that binds interleukin-13R.alpha.2...
2016/0340648 PURIFICATION OF FUNCTIONAL HUMAN ASTROCYTES
Compositions and methods are provided for the purification of astrocytes from biological samples or from in vitro cultures. An advantage of the methods of the...
2016/0340647 COMPOSITIONS AND METHODS FOR INDUCING DIFFERENTIATION OF STEM CELLS
Compositions and methods for inducing differentiation of stem cells such as cancer stem cells (CSCs), and increasing sensitivity of CSCs to at least one...
2016/0340646 METHOD FOR CELL CULTURE
A method for stem or progenitor cell culture. More precisely, the invention relates to a method for cell culture using one or more I.alpha.I (inter-alpha...
2016/0340645 DEFINITIVE ENDODERM CELLS AND HUMAN PLURIPOTENT STEM CELLS
Disclosed herein are methods of identifying one or more differentiation factors that are useful for differentiating cells in a cell population comprising...
2016/0340644 Microstructure for Particle and Cell SEparation, Identification, Sorting, and Manipulation
The invention relates to microscale cell separating apparatus which are able to separate cells on the basis of size of the cells, interaction of the cells with...
2016/0340643 METHOD OF PRODUCING CELL POPULATION WITH HIGH TARGET CELL PURITY
A method is disclosed of producing a cell population with a high target cell purity, including changing a character of contaminating cells in a cell population...
2016/0340642 METHODS FOR SELECTIVE INHIBITION OF PLURIPOTENT STEM CELLS
Provided herein are methods of reducing or eliminating undifferentiated pluripotent stem cells, where the methods comprise contacting an effective amount of a...
2016/0340641 STRUCTURE FOR ANIMAL CELL, METHOD FOR SEPARATING ANIMAL CELL, AND METHOD FOR ADJUSTING ELASTICITY OF SURFACE OF...
A structure used for animal cells is provided which includes an elastic body layer having a flat surface on which animal cells are left. The elastic body layer...
2016/0340640 METHOD FOR THE PROTEIN ENRICHMENT OF MICROALGAL BIOMASS
The invention relates to a method for the protein enrichment of a microalga of the genus Chlorella, cultivated under heterotrophic conditions. The method is...
2016/0340639 PROCESS FOR CULTURING BACTERIA OF THE FAMILY STREPTOCOCCACEAE
This invention relates to an improved process for culturing bacteria of the family Streptococcaceae (such as of the genus lactococcus), a medium for culturing...
2016/0340638 CENTRIFUGAL DYNAMIC FILTERING APPARATUS AND CELL SEPARATION SYSTEM USING SAME
The present invention directs to a centrifugal filtration device, for separating living cells, including a spindle (28), a rotary arm (211) which is connected...
2016/0340637 CELL MAGNETIC SORTING SYSTEM, SORTING APPARATUS, AND TREATMENT DEVICE
A cell magnetic sorting system comprises a continuous magnetic cell sorting apparatus. The continuous magnetic cell sorting apparatus comprises a rotating...
2016/0340636 CELL DETECTION DEVICE AND CELL DETECTION METHOD
A cell detection device and a cell detection method is provided with which it is possible to efficiently acquire images of cells to be measured. Cell detection...
2016/0340635 METHOD AND APPARATUS FOR ISOLATING INVASIVE AND METASTATIC CELLS FOR EVALUATING THERAPEUTICS AND PREDICTION OF...
Embodiments provide methods to produce an assembly that mimics in vitro the human microenvironment of a primary tumor site, a secondary distant organ, and...
2016/0340634 CULTURING DEVICE
A culturing device includes an incubator part. The incubator part includes an internal housing, a mounting part installed within the internal housing and...
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