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Patent # Description
2016/0348099 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF
The present disclosure provides modified nucleosides, nucleotides, and nucleic acids, and methods of using them.
2016/0348098 COMPOSITIONS AND METHODS FOR PREPARING OLIGONUCLEOTIDE SOLUTIONS
The present invention is directed to methods and compositions for generating a pool of oligonucleotides. The invention finds use in preparing a population or...
2016/0348097 COMPOSITIONS AND METHODS FOR ACTIVATING SILENT GENE CLUSTERS
The disclosure provides compositions and methods for producing natural products in microorganisms that are otherwise unexpressed, poorly expressed or poorly...
2016/0348096 NEGATIVE SELECTION AND STRINGENCY MODULATION IN CONTINUOUS EVOLUTION SYSTEMS
Strategies, systems, methods, reagents, and kits for phage-assisted continuous evolution are provided herein. These include strategies, systems, methods,...
2016/0348095 NUCLEIC ACIDS ANALYSIS
The present invention is partly based on the discovery that adverse factors can prevent an effective extraction of nucleic acids from a biological sample and...
2016/0348094 HIGHLY ACTIVE SILICA MAGNETIC NANOPARTICLES FOR PURIFYING BIOMATERIAL AND PREPARATION METHOD THEREOF
The present invention relates to a method for preparing highly active silica magnetic nanoparticles, highly active silica magnetic nanoparticles prepared by...
2016/0348093 Mobile Solid Phase Compositions for Use in Biochemical Reactions and Analyses
Compositions that include particle suspensions where such particle suspensions have characteristics for use in a variety of applications including, for...
2016/0348092 LYSIS BUFFERS FOR EXTRACTING NUCLEIC ACIDS
The present teachings relate to the extraction of nucleic acid from solid materials. Provided are useful compositions, methods and kits for obtaining nucleic...
2016/0348091 RAPID CELL PURIFICATION SYSTEMS
Methods and systems for purifying cells and/or viruses are provided. The sample is added to a well disposed in a medium. A potential is applied across the...
2016/0348090 POROUS MEMBRANE HAVING IMMOBILIZED ENZYME, POROUS MEMBRANE COMPOSITE INCLUDING THE SAME, AND PREPARATION METHOD...
Disclosed herein is a porous membrane having an immobilized enzyme wherein the enzyme is immobilized within pores which are three-dimensionally connected to...
2016/0348089 METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE FAMILY ENTEROBACTERIACEAE HAVING AN ATTENUATED...
The present invention provides a method for producing an L-amino acid such as a branched-chain L-amino acid by fermentation using a bacterium of the family...
2016/0348088 Colistin Synthetases and Corresponding Gene Cluster
PmxA synthetase involved in polymyxin E synthesis, comprising four adenylation sites, characterized in that the second adenylation site has at least 90%...
2016/0348087 GENETICALLY ENGINEERED MICROORGANISMS FOR THE PRODUCTION OF CHORISMATE-DERIVED PRODUCTS
The invention provides genetically engineered microorganisms and methods for producing chorismate-derived products, such as para-hydroxybenzoic acid,...
2016/0348086 Improved Carbon Dioxide Fixation Via Bypassing Feedback Regulation
Genetically engineered cells and methods are presented that allow for the production of various value products from CO.sub.2. Contemplated cells have a CBB...
2016/0348085 RECOMBINANT L-ASPARAGINASE FROM ZYMOMONAS
The present invention relates to the construction and optimization of synthetic genes from the Zymomonas mobilis L-asparaginase gene, the method for cloning...
2016/0348084 ALPHA-AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
The present invention relates to variants having alpha-amylaseactivity and polynucleotides encoding the variants. The invention also relates to nucleic acid...
2016/0348083 FACTORS FOR THE PRODUCTION AND ACCUMULATION OF POLYUNSATURATED FATTY ACIDS (PUFAS) DERIVED FROM PUFA SYNTHASES
Factors For the Production and Accumulation of Polyunsaturated Fatty Acids (PUFAs) Derived from PUFA Synthases Abstract Disclosed are novel enhancing factor...
2016/0348082 Microorganisms for Succinic Acid Production
The present invention relates to a modified microorganism having, compared to its wild-type, a reduced activity of the enzyme that is encoded by the pykA-gene....
2016/0348081 PIPECOLINIC ACID 4-HYDROXYLASE AND METHOD FOR PRODUCING 4-HYDROXY AMINO ACID USING SAME
The present invention provides a pipecolic acid 4-hydroxylase protein exemplified by the following (A), (B), and (C), having activity to react with L-pipecolic...
2016/0348080 ACYL-ACP REDUCTASE WITH IMPROVED PROPERTIES
The disclosure relates to acyl-ACP reductase (AAR) enzyme variants that result in improved fatty aldehyde and fatty alcohol production when expressed in...
2016/0348079 METHOD OF SCREENING LACTATE DEHYDROGENASE MUTANT, LACTATE DEHYDROGENASE MUTANT, POLYNUCLEOTIDE, VECTOR,...
A method of screening a microorganisim having a mutant lactate dehydrogenase with increased activity, a mutant lactate dehydrogenase polypeptide, a...
2016/0348078 ENGINEERED LEATHER AND METHODS OF MANUFACTURE THEREOF
Engineered animal skin, hide, and leather comprising a plurality of layers of collagen formed by cultured animal collagen-producing (e.g., skin) cells. Layers...
2016/0348077 FUSION PROTEIN FOR INDUCING PLURIPOTENT STEM CELLS AND APPLICATION METHOD THEREOF
Provided is a protein coded by a gene related to cell totipotency and a transcriptional activation domain of a mammalian YAP protein or a fusion protein of a...
2016/0348076 The Usage of Odontogenic Stem Cells and Genetically Modified Odontogenic Stem Cells
Provided in the present invention are odontogenic stem cells and a use of genetically modified odontogenic stem cells for treating periodontal disease,...
2016/0348075 IMMORTALIZED CELL
The present invention relates to an immortalized cell, an immortalized cell line comprising said immortalized cell, a cell culture comprising the immortalized...
2016/0348074 METHODS AND COMPOSITIONS FOR TREATING CELLS FOR TRANSPLANT
The invention relates to methods for generating viral-free cells using nucleases for use in transplantation. The nucleases may be CRISPR/Cas9 complexes with...
2016/0348073 MODIFIED T CELLS AND METHODS OF MAKING AND USING THE SAME
Disclosed herein are modified primary human T cells and populations thereof comprising a genome in which the CTLA4, PD1, TCRA, TCRB, and/or B2M genes have been...
2016/0348072 Activation and Expansion of T-Cells Using an Engineered Multivalent Signaling Platform as a Research Tool
Provided are a system and methods for selectively inducing expansion of a population of T cells in the absence of exogenous growth factors, such as ...
2016/0348071 PLURIPOTENT CELLS
Pluripotent cells that are immunopositive for both the neural progenitor marker nestin and a pluripotent cell marker are provided. The cells exhibit rapid...
2016/0348070 METHODS AND COMPOSITIONS FOR PRODUCING STEM CELL DERIVED DOPAMINERGIC CELLS FOR USE IN TREATMENT OF...
The present disclosure relates to methods for producing dopaminergic cells and evaluating their functionality. When pluripotent human embryonic stem cells are...
2016/0348069 MESENDODERM AND MESODERM CELL POPULATIONS
The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. In...
2016/0348068 POMEGRANATE DERIVED CELL CULTURE AND METHODS FOR PREPARING AND USING THE SAME
The invention relates to a large scale process for the in vitro production of a cell culture of pomegranate cells, to a product prepared from such cells and to...
2016/0348067 SELF-ASSEMBLING CELL AGGREGATES AND METHODS OF MAKING ENGINEERED TISSUE USING THE SAME
A composition comprising a plurality of cell aggregates for use in the production of engineered organotypic tissue by organ printing. A method of making a...
2016/0348066 CELL TRAY AND DEVICE, METHOD AND SYSTEM FOR PRODUCING CELL STRUCTURE
Provided are: a cell tray provided with a concave part for supporting a cell aggregate and a hole formed on the bottom of the concave part; and a device for...
2016/0348065 CULTURE MEDIUM FOR HEMATOPOEITIC STEM CELLS AND THE APPLICATIONS THEREOF AS WELL AS THE STEM CELLS CULTURE METHOD
The present invention discloses a culture medium for hematopoietic stem cells and the applications thereof as well as the stem cells culture method, which...
2016/0348064 PENTOSE-FERMENTING STRAIN WITH OPTIMIZED PROPAGATION
The present invention relates to a method for obtaining a strain capable of efficiently propagating in a low nutritive potential medium, capable of...
2016/0348063 METHOD FOR CULTIVATING ANTRODIA CINNAMOMEA AND FORMULA COMPOSITION OF A CULTURE MEDIUM FOR CULTIVATING ANTRODIA...
A method for cultivating antrodia cinnamomea includes transplanting bacterial strains of antrodia cinnamomea into a petri dish receiving culture ingredients....
2016/0348062 METHODS OF MICROALGAE CULTIVATION FOR INCREASED RESOURCE PRODUCTION
Methods of inducing or increasing lipid and protein production in microalgae are disclosed. Methods of enhancing microalgae biomass are also disclosed. The...
2016/0348061 SYSTEM AND METHOD FOR CELL SEPARATION
The invention relates to a system and a method for cell separation via a filter, with a powder bag which can be arranged in a recirculation circuit and is...
2016/0348060 SYSTEM AND METHOD OF PRESERVATION, STORAGE AND TRANSPORT OF BIOLOGICAL MATERIALS
The present application discloses a system and method for preservation, storage and transport of biological materials by the use of at least one deformable...
2016/0348059 INTEGRATED BIO-REACTOR MONITOR AND CONTROL SYSTEM
Systems and methods for automatically controlling conditions of a process are disclosed. In one example, a controller is programmed with a sequence of steps...
2016/0348058 APPARATUS FOR MEASURING CELL ACTIVITY AND METHOD FOR ANALYZING CELL ACTIVITY
The present invention relates to an apparatus that uses shadow images of cells to continuously measure cell activity at a high processing rate in order to...
2016/0348057 Cell Colony Area Specifying Apparatus, Cell Colony Area Specifying Method, and Recording Medium
By deleting a small area from an initial boundary image, a provisional boundary image is obtained (Step S211). A thinning processing is performed on the...
2016/0348056 PORTABLE DISPOSABLE RE-USABLE CULTURE DEVICE FOR RAPID DIAGNOSIS OF INFECTIOUS AGENTS
The present invention is directed to compositions, tools, methods and devices to culture microorganisms and, in particular, to compositions, tools, methods and...
2016/0348055 DUAL CHAMBER SELECTIVELY PERMEABLE DEVICE FOR CELL CULTURE AND THE APPLICATIONS THEREOF
The present invention discloses a dual chamber selectively permeable cell culture device, wherein, the said device includes: at least two cell culture...
2016/0348054 Biogas stirring device for anaerobic tank
A biogas stirring device for an anaerobic tank includes: a biogas compressor, a biogas distributer, and gas inlet valves; wherein the biogas distributer...
2016/0348053 DISPERSING FEEDSTOCKS AND PROCESSING MATERIALS
Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. For example,...
2016/0348052 In Vitro Pharmacokinetics/Pharmacodynamics Bellows Perfusion System for Enhancing Effectiveness of Cancer...
Provided herein is a continuous cell perfusion model system that provides useful pharmacokinetic and pharmacodynamic information on the application of new...
2016/0348051 CULTURE CONTAINER, GEL MATERIAL, AND CULTURE SYSTEM
A culture container includes a gel section constituted by a material containing a stimulus-responsive gel which expands or contracts in response to a stimulus...
2016/0348050 METHOD AND APPARATUS FOR CELL ISOLATION, GROWTH, REPLICATION, MANIPULATION, AND ANALYSIS
According to an aspect of some embodiments, an apparatus for isolation and cytometric analysis of cells from a liquid medium is provided. The apparatus...
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