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Patent # Description
2016/0346299 METHOD FOR CONTROLLED RELEASE ORAL DOSAGE OF A VITAMIN D COMPOUND
A stable, controlled release formulation for oral dosing of vitamin D compounds is disclosed. The formulation is prepared by incorporating one or more vitamin...
2016/0346298 HORMONE DELIVERY SYSTEM AND METHOD
A hormone delivery system and method are provided for administering bioidentical human hormones using a combination of modalities for the treatment of human...
2016/0346297 Pharmaceutical Compositions Affecting Mitochondrial Redox State and Methods of Treatment
Provided herein are methods for treating diseases, disorders and/or medical conditions with pharmaceutical compositions consisting of an association of active...
2016/0346296 SUBSTITUTED TRIAZOLOBENZODIAZEPINES
This invention relates to novel substituted triazolobenzodiazepines of the Formula (I), wherein each of the variables are defined herein and pharmaceutically...
2016/0346295 Selective Estrogen Receptor Modulators With Short Half-Lives and Uses Thereof
The present invention relates to the long-term administration of a selective estrogen receptor modulator (SERM) with a short half-life for the treatment of a...
2016/0346294 TREATMENTS FOR RESISTANT ACNE
The present disclosure relates generally to novel molecules, compositions, and formulations for treatment of bacterial infections in general and more...
2016/0346293 METHOD FOR TREATING CANCER
The present invention provides a method for treating or alleviating a symptom of a disorder, e.g., immune evasion, cancer-cell induced immune dysfunction,...
2016/0346292 PHARMACEUTICAL COMBINATIONS COMPRISING A PYRIDO [4,3-D] PYRIMIDINE DERIVED HSP90-INHIBITOR AND A HER2 INHIBITOR
A pharmaceutical combination comprising an Hsp90 inhibitor and an HER2 inhibitor, and methods of using the combination to treat proliferative disorders.
2016/0346291 COMPOSITIONS AND THERAPEUTIC METHODS FOR ACCELERATED PLAQUE REGRESSION
The invention comprises methods for treating and/or preventing cardiovascular, cholesterol, and lipid related disorders, including atherosclerosis,...
2016/0346290 NOVEL USE OF SIGMA-1 RECEPTOR AGONIST COMPOUNDS
The present invention is directed to compositions and methods for the prevention, inhibition, and/or treatment of progressive fibrosis present in various...
2016/0346289 Fixed-Dose Combinations of Antiviral Compounds
The present disclosure is directed to compositions comprising blended materials comprising a first solid dispersion formulation, which comprises an HCV...
2016/0346288 1-[(3-CYANO-PYRIDIN-2-YL)METHYL]-3-METHYL-7-(2-BUTYN-1-YL)-8-[3-(R)-AMINO-- PIPERIDIN-1-YL]-XANTHINE FOR THE...
A method of treating a metabolic disorder or metabolic disease includes administering a pharmaceutically effective dose of ...
2016/0346287 METHOD OF TREATING VIRAL INFECTIONS
The present invention is directed to methods and compositions employing 9-(4-hydroxy-2-(hydroxymethyl)butyl)guanine ("H2G") or derivatives or analogs thereof...
2016/0346286 Heteroaryl Substituted Pyrrolo[2,3-B] Pyridines And Pyrrolo[2,3-B] Pyrimidines As Janus Kinase Inhibitors
The present invention provides heteroaryl substituted pyrrolo[2,3-b]pyridines and heteroaryl substituted pyrrolo[2,3-b]pyrimidines that modulate the activity...
2016/0346285 METHODS AND KITS TO PREDICT THERAPEUTIC OUTCOME OF BTK INHIBITORS
Methods of tests that assess the expression of DPC4 (SMAD4) to identify subjects with pancreatic cancer that are likely or unlikely to respond to treatment...
2016/0346284 SUBSTITUTED PYRAZOLOPYRIMIDINES AS GLUCOCEREBROSIDASE ACTIVATORS
Substituted pyrazolopyrimidines and dihydropyrazolopyrimidines and related compounds, their methods of manufacture, compositions containing these compounds,...
2016/0346283 Various Compounds as Autophagy Stimulants
The invention relates to promoting autophagy in the treatment or prevention of autophagy related disorders, such as various forms of cancer; liver disease,...
2016/0346282 METHODS AND COMPOSITIONS FOR TREATING ABNORMAL CELL GROWTH
The present invention relates to, inter alia, combinations, methods, compositions, and oral dosage forms of a FAK inhibitor and a MEK inhibitor, for treating...
2016/0346281 TREATMENT OF NEUROLOGICAL DISORDERS
Provided herein is technology relating to treatment of neurological disorders and particularly, but not exclusively, to methods and compositions for treating...
2016/0346280 COMPOSITIONS AND METHODS OF TREATING PULMONARY HYPERTENSION
Provided are formulations comprising therapeutically effective amounts of ambrisentan or a pharmaceutically acceptable salt thereof and tadalafil or a...
2016/0346279 Histone Deacetylase 6 Selective Inhibitors for the Treatment of Cisplatin-Induced Peripheral Neuropathy
Disclosed are methods for treating cisplatin-induced peripheral neuropathy in a subject in need thereof comprising administering to the subject a...
2016/0346278 PARENTERAL FORMULATIONS OF LIPOPHILIC PHARMACEUTICAL AGENTS AND METHODS FOR PREPARING AND USING THE SAME
There may be provided compositions of lipophilic pharmaceutical agents with improved solubility and stability. For example, there may be provided a non-aqueous...
2016/0346277 PROCASPASE 3 ACTIVATION BY COMBINATION THERAPY
The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods...
2016/0346276 COMPOSITIONS AND METHODS FOR INCREASING THE METABOLIC LIFETIME OF DEXTROMETHORPHAN AND RELATED PHARMACODYNAMIC...
Dosage forms, drug delivery systems, and methods related to sustained release of dextromethorphan or improved therapeutic effects are disclosed. Typically,...
2016/0346275 PHARMACEUTICAL FORMULATIONS FOR SUSTAINED RELEASE OF SEBACOYL DINALBUPHINE ESTER
The present invention relates to injectable, extended-release, pharmaceutical formulations comprising a nalbuphine ester prodrug homogenously dissolved in a...
2016/0346274 ABUSE-RESISTANT DRUG FORMULATIONS WITH BUILT-IN OVERDOSE PROTECTION
Disclosed are solid oral pharmaceutical compositions that that are intended to provide protection against overdose and tampering, as well as abuse deterrence....
2016/0346273 METHODS FOR TREATING PRURITUS
The present invention relates to methods for treating pruritus with anti-pruritic compositions.
2016/0346272 TREATMENT OF BREAST CANCER WITH LIPOSOMAL IRINOTECAN
Provided are methods for treating breast cancer in a patient by administering effective amounts of liposomal irinotecan sucrosofate (MM-398). The breast cancer...
2016/0346271 COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY
Compounds of formula I, defined herein, act both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists and are useful for treating diseases...
2016/0346270 BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2
The present invention relates to new benzoquinoline inhibitors of vesicular monoamine transporter 2 (VMAT2), pharmaceutical compositions thereof, and methods...
2016/0346269 COMBINATION THERAPY
Described herein are compounds and compositions for treating glaucoma and/or reducing intraocular pressure. Compositions may comprise an isoquinoline compound...
2016/0346268 AMINOESTER DERIVATIVES
Compounds of formula (I) defined herein are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists and are useful for...
2016/0346267 Pharmaceutical Composition Comprising Apixaban
The present invention relates to a pharmaceutical composition comprising apixaban, in particular to a pharmaceutical composition comprising apixaban and a...
2016/0346266 REDUCTION OR PREVENTION OF ALCOHOL REACTION WITH DIETARY SUPPLEMENTS
The present invention is directed to compositions for preventing or reducing the flush and other unpleasant symptoms that sometimes accompany the consumption...
2016/0346265 Use of Quaternary Pyridinium Salts as Vasoprotective Agents
The invention relates to the use of quaternary pyridinium salts of formula (I), ##STR00001## wherein R is NH.sub.2, CH.sub.3, or N(H)CH.sub.2OH group, and X is ...
2016/0346264 5-SUBSTITUTED ISOINDOLINE COMPOUNDS
This invention relates to 5-substituted isoindoline compounds, and pharmaceutically acceptable salts, solvates, stereoisomers, and prodrugs thereof. Methods of...
2016/0346263 CRYSTALLINE POLYMORPHS OF THE FREE BASE OF ...
Disclosed are crystalline free base ansolvate forms of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- ehyde (or Compound 1), such as...
2016/0346262 Method of enhancing lysosomal alpha-Galactosidase A
A method of enhancing the activity of lysosomal .alpha.-Galactosidase A (.alpha.-Gal A) in mammalian cells and for treatment of Fabry disease by administration...
2016/0346261 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ADDICTION AND OTHER NEUROPSYCHIATRIC DISORDERS
The present invention is based, in part, on our discovery that certain types of therapeutic agents can be used in combination to treat a variety of...
2016/0346260 AMINOESTER DERIVATIVES
Compounds of formula (I) defined herein are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists and are useful for...
2016/0346259 Compositions and Methods for the Treatment of Presbyopia
The invention provides compositions and methods for the treatment of presbyopia. The compositions preferably comprise aceclidine and a polyol. The compositions...
2016/0346258 SOLID DISPERSIONS OF INSOLUBLE DRUG AND PREPARATION METHOD THEREOF
The present invention relates to a solid dispersion characterized in that it comprises carbamic acid 3-(4-benzyloxy-phenyl)-isoxazol-5-ylmethyl ester as an...
2016/0346257 PHARMACEUTICAL COMPOSITIONS COMPRISING AN AROMATSE INHIBITORS
The present invention relates to low-dose pharmaceutical compositions comprising the aromatase inhibitor ...
2016/0346256 AMIDE COMPOUND AND MEDICINAL USE THEREOF
A compound of formula [I-W]: ##STR00001## wherein each symbol is as defined in the description, or a pharmaceutically acceptable salt thereof.
2016/0346255 METHODS, AGENTS AND COMPOSITIONS FOR TREATMENT OF INFLAMMATORY CONDITIONS
The present invention relates to the screening, diagnosis, prognostic evaluation, and treatment or prevention of age associated inflammation, chronic...
2016/0346254 PROTEIN KINASE INHIBITORS
A compound of formula (I), wherein R.sub.3, R.sub.4, G, B, M, and Z are as defined in the claims, and pharmaceutically acceptable salts thereof are disclosed....
2016/0346253 TOPICAL PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF PILONIDAL SINUS WOUNDS
A topical composition comprising about 5 wt % to about 12.5 wt % of metronidazole or a pharmacologically acceptable salt thereof in a non-aqueous vehicle. The...
2016/0346252 NOVEL NITROIMIDAZOLE FORMULATIONS AND USES THEREOF
Embodiments described herein are directed to novel pharmaceutical compositions comprising a plurality of microgranules comprising nitroimidazole compounds, and...
2016/0346251 Myogenesis Promotor, Muscle Atrophy Inhibitor, Medical Composition and Taz Activator
The invention provides a novel myogenesis promotor, a novel muscle atrophy inhibitor, a novel composition or a novel TAZ activator. The myogenesis promotor,...
2016/0346250 METHODS FOR TREATING AND DIAGNOSING BLINDING EYE DISEASES
This invention relates to, in part, methods and compositions that are useful for the diagnosis, treatment, or prevention of a blinding eye disease, including...
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