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Patent # Description
2016/0355489 NEW COMPOUNDS HAVING A SELECTIVE PDE4D INHIBITING ACTIVITY
Compounds of formula (I), wherein Z=cyclopentyl. cyclopropylmethyl, --CH.sub.3; R'=--CH.sub.3, CHF.sub.2, X=formula (II) (III) (IV) (V) Y=--CO;...
2016/0355488 TRIAZOLES FOR THE TREATMENT OF DEMYELINATING DISEASES
The invention relates to triazole compounds of formula I and I' or pharmaceutically acceptable salts thereof, useful as modulators of demyelinating diseases: ...
2016/0355487 PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS
The present invention provides novel phenazine derivatives, such as compounds of Formula (I) and (II), and pharmaceutically acceptable salts thereof. The...
2016/0355486 METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS
The present invention relates to methods and intermediates useful for the synthesis of protein deacetylase inhibitors.
2016/0355485 BENZIMIDAZOLE DERIVATIVES AS SELECTIVE BLOCKERS OF PERSISTENT SODIUM CURRENT
The present invention is directed to a compound of Formula I ##STR00001## or a pharmaceutically acceptable salt thereof; wherein R, R.sup.1, R.sup.2, R.sup.3,...
2016/0355484 ARTICLES AND METHODS COMPRISING PERSISTENT CARBENES AND RELATED COMPOSITIONS
Articles and methods comprising persistent carbenes are provided, as well as related compositions. In some embodiments, a persistent carbene may be associated...
2016/0355483 COMPOUND BINDING TO PPARG BUT NOT ACTING AS PROMOTER AND PHARMACEUTICAL COMPOSITION FOR TREATING PPARG-RELATED...
The present invention relates to a compound inhibiting CDK5-mediated PPARG phosphorylation and a pharmaceutical composition for treating PPARG-related diseases...
2016/0355482 6-HETEROARYLOXY- OR 6-ARYLOXY-QUINOLINE-2-CARBOXAMIDES AND METHOD OF USE
Compounds of formula (I) ##STR00001## and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein R.sup.1, R.sup.2, and...
2016/0355481 TYPE 4 PREPILIN PEPTIDASE INHIBITORS AND METHODS OF USE
Compounds for inhibiting Type 4 Prepilin Peptidases are provided as are methods of using the compounds as an ti-bacterial agents.
2016/0355480 SUBSTITUTED PYRIDINES AND METHOD OF USE
The invention discloses compounds of Formula I ##STR00001## wherein X, R.sup.1, R.sup.2, and R.sup.3 are as defined herein. The present invention relates to...
2016/0355479 SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS
Described herein are compounds that modulate the activity of TNAP. In some embodiments, the compounds described herein inhibit TNAP. In certain embodiments,...
2016/0355478 THERAPEUTIC AGENTS
A compound of formula (I) or a compound of formula (II) or pharmaceutically acceptable salts thereof, wherein R1-R7 and X are as defined in the description,...
2016/0355477 INDOLE CARBOXAMIDE DERIVATIVES AND USES THEREOF
A compound of Formula (I) is provided that has been shown to be useful for treating a disease, disorder or syndrome that is mediated by the transportation of...
2016/0355476 Indole and benzimidazolecarboxamides as insecticides and acaricides
The present invention relates to compounds of the general formula (I), ##STR00001## in which R.sup.a to R.sup.6, G and n have the meanings given in the ...
2016/0355475 NOVEL INDOLE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
The present invention provides a novel indole derivative compound, an isomer thereof, a pharmaceutically acceptable salt thereof, or a hydrate or solvate...
2016/0355474 3,3'-DISUBSTITUTED INDOLINES AS INHIBITORS OF CHOLESTEROL ESTER TRANSFER PROTEIN
3,3'-Disubstituted indoline compounds, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising...
2016/0355473 BETA-LACTAM CHOLESTEROL ABSORPTION INHIBITORS
The present invention relates to the novel compounds represented by Formula (Ia) or (Ib) and to their pharmaceutical preparations for the treatment of...
2016/0355472 PROCESS FOR PREPARING MESOTRIONE
A process for the preparation of mesotrione enolate is provided. The process comprises providing a solution of mesotrione in an organic solvent and contacting...
2016/0355471 PREPARATION OF HYDROXY-BENZYLBENZENE DERIVATIVES
Methods for preparing intermediates of SGLT2 inhibitors are provided, including crystalline forms and methods of crystallizing intermediates.
2016/0355470 CYCLIC PROCESS FOR PRODUCING TAURINE
There is disclosed a process for producing taurine by the ammonolysis of alkali isethionate in the presence of alkali ditaurinate or alkali tritaurinate, or...
2016/0355469 ANTICONVULSANT COMPOUNDS
The present application relates to compounds and methods for reducing the severity of convulsant activity, or epileptic seizures.
2016/0355468 PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-CHLORO-6-(SUBSTITUTED)PICOLINATES
4-Amino-5-fluoro-3-chloro-6-(substituted)picolinates are prepared from trifluoroacetic acid, p-methoxyaniline, a C.sub.1-C.sub.4 alkyl propiolate and a...
2016/0355467 TITANIUM-SILICALITE MOLECULAR SIEVE, METHOD FOR PREPARING THE SAME AND METHOD FOR PREPARING CYCLOHEXANONE OXIME...
The present invention provides a titanium-silicalite molecular sieve and a method for preparing the same. The method includes the steps of preparing a mixture...
2016/0355466 CYCLOPENTENE AND CYCLOPENTADIENE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS
The present invention relates to cyclopent(adi)ene compounds of formula I ##STR00001## wherein the variables are as defined in the claims and description. The ...
2016/0355465 NOVEL MODIFIED CURCUMINS AND THEIR USES
This invention provides a compound having the structure ##STR00001## wherein .alpha., .beta., A, B, and R.sub.1-R.sub.4 are defined herein. This invention also...
2016/0355464 FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE
Fumarate compounds, pharmaceutical compositions comprising the fumarate compounds, and methods of using fumarate compounds and pharmaceutical compositions for...
2016/0355463 PHYSIOLOGICAL COOLING COMPOUNDS
Physiological cooling compounds of the structure: ##STR00001## where R.sub.1 is p-menthyl or 2,3,4-trimethylpent-3-yl group and R.sub.2-R.sub.8 are hydrogen or...
2016/0355462 BICYCLIC ANALGESIC COMPOUNDS
Analgesic compounds for treatment of pain or fever, comprising a bicyclopentane moiety linked to an amine, combinations of the compounds with opioid analgesic...
2016/0355461 METHOD FOR PRODUCING NOVEL ALI CYCLIC ESTER COMPOUND, NOVEL ALICYCLIC ESTER COMPOUND, (METH)ACRYLIC COPOLYMER...
Provided are a resist and a compound for the resist improving the sensitivity, the resolution and the line edge roughness (LER) in a good balance without...
2016/0355460 Preparation of 18F-FLUCICLOVINE
The present invention provides a method for the production of [.sup.18F]-FACBC which has advantages over know such methods. Also provided by the present...
2016/0355459 Small Molecule Inhibitors of Dusp6 and Uses Therefor
Compounds that stimulate fibroblast growth factor production, and thus cell growth are provided. Also provided are compositions comprising the compounds and...
2016/0355458 INHIBITORS OF COGNITIVE DECLINE
Compounds that are central nervous system drug candidates for the treatment of cognitive decline and, more particularly, Alzheimer's disease are provided....
2016/0355457 Solid Forms Comprising(-)-O-Desmethylvenlafaxine And Uses Thereof
Solid forms comprising a compound useful in the treatment, prevention and management of various conditions and diseases are provided herein. In particular, the...
2016/0355456 PLANT EXTRACTS AND USE THEREOF
An object of the present invention is to provide a plant extract which comprises o-diphenol type chlorogenic acids in a high concentration. Also, it is to...
2016/0355455 COMPOUNDS AND METHODS FOR DELIVERY OF PROSTACYCLIN ANALOGS
This invention pertains generally to prostacyclin formulations and methods for their use in promoting vasodilation, inhibiting platelet aggregation and...
2016/0355454 WATER-INSOLUBLE RUTHENIUM CATALYST COMPOSITION FOR USE IN AQUEOUS HYDROGENATION REACTIONS
The invention relates to a method for converting a precatalyst complex to an active catalyst complex, wherein the precatalyst complex and the active catalyst...
2016/0355453 PROCESS FOR PRODUCING FLUORINE-CONTAINING OLEFIN
In the production of fluorine-containing olefins using a chlorine-containing alkane or a chlorine-containing alkene as a starting material, a process for...
2016/0355452 METHOD FOR PRODUCING (BROMOMETHYL)CYCLOPROPANE AND (BROMOMETHYL)CYCLOBUTANE
The present invention relates to a method for obtaining high purity (bromomethyl)cyclopropane and (bromomethyl)cyclobutane, starting respectively with...
2016/0355451 REMOVAL OF AROMATIC IMPURITIES FROM AN ALKENE STREAM USING AN ACID CATALYST, SUCH AS AN ACIDIC IONIC LIQUID
A process for the preparation of a chemical composition comprising an aromatic compound .alpha. in a concentration B by weight, based on the total weight of...
2016/0355450 PROCESS FOR PREPARING 1,3-BUTADIENE FROM N-BUTENES BY OXIDATIVE DEHYDROGENATION
A process for preparing butadiene from n-butenes, comprising the steps of A) providing an input gas stream a1 comprising n-butenes; B) feeding the input gas...
2016/0355449 Hydrogenation Using Highly Selective Catalyst
A process comprising hydrogenating a highly unsaturated hydrocarbon in the presence of a first hydrogenation catalyst and a second hydrogenation catalyst to...
2016/0355448 PROCESSES FOR THE PREPARATION OF AN OLEFINIC PRODUCT
The invention provides a process for the preparation of an olefinic product, the process comprising the steps of: (a) reacting an oxygenate feedstock,...
2016/0355447 ADDITIVE MANUFACTURED COMBUSTIBLE ELEMENT WITH FUEL AND OXIDIZER
A combustible element includes regions of fuel material interspersed with regions of oxidizer material. The element may be made by additive manufacturing...
2016/0355446 APPARATUS FOR COMPOSTING ORGANIC MATTER
A composter for various organic debris is designed to remove such debris, namely yard waste and other organic materials, and promote an effective composting...
2016/0355445 AGRICULTURAL MICROBIAL INOCULANT COMPOSITIONS AND USES THEREOF
The present disclosure provides novel agricultural microbial inoculant compositions for uses in promoting plant growth, plant productivity and/or soil quality....
2016/0355444 BIOMASS PROCESSING METHODS AND SYSTEMS
A process for producing desired compounds from biomass, including treating a lignocellulosic waste stream in some embodiments. The waste stream is conditioned...
2016/0355443 High Value Organic Containing Fertilizers and Methods of Manufacture
The invention is directed to manufacturing fertilizers having commercial levels of nitrogen reacted with organic substances. The process comprises treatment of...
2016/0355442 Methods and Compositions for Concrete Production
The invention provides compositions and methods directed to carbonation of a cement mix during mixing. The carbonation may be controlled by one or more...
2016/0355441 Post-Batching CMA Dosing Into Concrete
The present invention relates to mitigating the deleterious effect of clays, which are born or conveyed by sand aggregates, crushed rock, gravel, and other...
2016/0355440 POLYCRYSTALLINE DIAMOND COMPACTS
Embodiments of the invention relate to polycrystalline diamond ("PCD") exhibiting enhanced diamond-to-diamond bonding. In an embodiment, PCD includes a...
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