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Patent # Description
2016/0361408 INFLUENZA VIRUS VACCINES AND USES THEREOF
Provided herein are chimeric influenza hemagglutinin (HA) polypeptides, compositions comprising the same, vaccines comprising the same, and methods of their use.
2016/0361407 RECOMBINANT LACTOCOCCUS LACTIS EXPRESSING ESCHERICHIA COLI COLONIZATION FACTOR ANTIGEN I (CFA/I) FIMBRIAE AND...
The present disclosure relates generally to therapeutic compositions comprising recombinant bacteria. Further, the disclosure elaborates upon methods of...
2016/0361406 ACINETOBACTER BAUMANNII ANTIGENS AND THE USES THEREOF
The present invention relates to an isolated polypeptide antigen of Acinetobacter baumannii, comprising at least an amino acid sequence selected from the group...
2016/0361405 Dock-and-Lock (DNL) Vaccines for Cancer Therapy
The present invention concerns methods and compositions for forming anti-cancer vaccine DNL complexes using dock-and-lock technology. In preferred embodiments,...
2016/0361404 Methods and compositions for inhibition of Treg cells
The present invention relates to methods of suppressing the immune tolerance of a disease or disease antigens in a patient. The method also promotes the...
2016/0361403 Consensus Prostate Antigens, Nucleic Acid Molecule Encoding The Same And Vaccine And Uses Comprising The Same
Provided herein are consensus amino acid sequences of prostate antigens that are capable of breaking tolerance in a targeted species, including PSA, PSMA,...
2016/0361402 ENHANCING T CELL ACTIVATION USING ALTERED MHC-PEPTIDE LIGANDS
Materials and methods for identifying and using MEW molecule variants for activating self-reactive T cells in a peptide-specific manner, and their use to focus...
2016/0361401 COMPOSITIONS AND METHODS FOR THE TREATMENT OF HER2/NEU OVER-EXPRESSING TUMORS
This invention provides compositions and methods for treating and vaccinating against a HER2/neu antigen-expressing tumor and inducing an immune response...
2016/0361400 DNA VECTOR AND TRANSFORMED TUMOR CELL VACCINES
Customized whole cell cancer vaccines can be produced from autologous (ex vivo or in situ) or allogeneic human or veterinary patient cell lines. Cells are...
2016/0361399 THERAPEUTIC IMMUNE MODULATION BY STEM CELL SECRETED EXOSOMES
Disclosed are methods, compositions of matter, and protocols useful for the induction of a therapeutic immune modulatory response through administration of...
2016/0361398 METHOD FOR THE TREATMENT OF MULTIPLE SCLEROSIS
The disclosure is in the field of immunology and provides means and methods for the treatment of multiple sclerosis. More in particular, the disclosure relates...
2016/0361397 IMMUNOMODULATORY THERAPY FOR TYPE 1 DIABETES MELLITUS AUTOIMMUNITY
A composition for treating type 1 diabetes mellitus autoimmunity can include a therapeutically effective amount of two or more overlapping fragments of...
2016/0361396 AQUAPORIN 2 PROTECTS CATTLE FROM TICKS AND TICK-BORNE PARASITES
A novel method of using an aquaporin protein from Rhipicephalus microplus (RmAQP2), fragments of RmAQP2, and/or the cDNA encoding RmAQP2 and/or the fragments...
2016/0361395 PREVENTION AND REDUCTION OF BLOOD LOSS
Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic...
2016/0361394 TREATMENT OF HEREDITARY ANGIOEDEMA WITH C1 INHIBITOR
A method for treating acute attacks of hereditary angioedema (HAE) whereby a first does and a second dose of a recombinant C1 esterase inhibitor is...
2016/0361393 TOPICAL STING/BITE FORMULATION AND METHOD OF USE
A topical sting/bite treatment compound and method of making same comprising combining effective amounts of: a natural enzyme; a natural abrasive; a natural...
2016/0361392 METHODS AND PHARMACEUTICALS FOR TREATMENT OF VIRAL INFECTIONS OF THE EYE
Viral infections of the eye, and particularly viral infections in the Herpesviridae and Adenoviridae families, can be treated by administration of a...
2016/0361391 REDUCTION OF TRAF1 LEVELS COMBINED WITH NUTRIENT STRESS FOR TREATING LYMPHOCYTE-RELATED CANCERS
The present disclosure provides methods and uses for treating lymphocyte related cancers comprising administering a nutrient stress-inducing agent in...
2016/0361390 GLP-1 RECEPTOR AGONIST COMPOUNDS FOR OBSTRUCTIVE SLEEP APNEA
The disclosure provides, among other things, the use of GLP-1 receptor agonist compounds to treat obstructive sleep apnea. The GLP-1 receptor agonist compounds...
2016/0361389 METHOD FOR DELIVERING INTERFERON-BETA
The method described herein reduces the amount of aggregating metal released into solutions of Interferon-.beta.
2016/0361388 METHOD AND COMPOSITION FOR THE TREATMENT OF MODERATE TO SEVERE KERATOCONJUNCTIVITIS SICCA
The present invention relates to topical ophthalmic compositions for treating or preventing epithelial lesions or ophthalmic disorders, including dry eye or...
2016/0361387 ACTIVATORS OF CXCR3 FOR THE TREATMENT OF ANGIOPATHIES OF THE EYE
The present disclosure describes methods of treating angiogenic disorders of the eye, such as macular degeneration, restenosis following glaucoma treatment or...
2016/0361386 Methods and Compositions for Inducing Differentiation of Human Brown Adipocyte Progenitors
This disclosure relates to compositions and methods for recruiting brown adipocytes in vitro and in vivo from brown adipocyte progenitor cells found in human...
2016/0361385 METHOD FOR TREATING ALZHEIMER'S DISEASE USING SUPERIOR STABILITY TUBULIN CONSRUCTS
A method of providing a therapeutic benefit to a patient for Alzheimer's Disease (AD) is disclosed. A superior stabilizing-tubulin (SS-tubulin) is ...
2016/0361384 COSMETIC USE OF DERMICIDIN, OR ANALOGUES OR FRAGMENTS THEREOF, FOR THE PREVENTION AND/OR TREATMENT AND...
Cosmetic or therapeutic, in particular dermatological, use of dermicidin, or analogues or fragments thereof, for preventing the appearance of imperfections,...
2016/0361383 LIQUID NUTRITIONAL FORMULA FOR TYROSINEMIA PATIENTS
Liquid metabolic formulas for dietary management of tyrosinemia, including nutritional formulas and hydration beverages (sport drinks).
2016/0361382 MICROBICIDAL COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS
A composition is provided comprising an electrospun fiber having a surface with a biological adhesive moiety conjugated to the surface of the electrospun...
2016/0361381 TOPICAL COMPOSITION COMPRISING AN ANTIBACTERIAL AGENT
The present invention relates to a pharmaceutical composition suitable for topical application to the body and which comprises an antibacterial agent that is...
2016/0361380 COMBINATION COMPOSITIONS FOR TREATING DISORDERS REQUIRING REMOVAL OR DESTRUCTION OF UNWANTED CELLULAR...
The embodiments include methods of treating conditions requiring removal or destruction of cellular elements, such as benign or malignant tumors using...
2016/0361379 Use of CHEC Peptides to Treat Neurological and Cardiovascular Diseases and Disorders
The present invention describes compositions and methods for treating and preventing non-degenerative neurological diseases and disorders associated with...
2016/0361378 MULTIVALENT/MULTIFUNCTIONAL LIGANDS WITH AGONIST ACTIVITIES AT OPIOID RECEPTORS AND ANTAGONIST ACTIVITIES AT...
A compound for treatment of pain comprising a single multivalent/multifunctional ligand with agonist activity at opioid receptors and with antagonist activity...
2016/0361377 METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OPHTHALMIC CONDITIONS
The disclosure provides methods of preventing or treating ophthalmic diseases or conditions in a mammalian subject. The methods comprise administering an...
2016/0361376 CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS
The invention described herein pertains to the diagnosis, imaging, and/or treatment of pathogenic cell populations. In particular, the invention described...
2016/0361375 INHIBITORS OF HEPATITIS C VIRUS
Compounds of Formula I are disclosed ##STR00001## As well as pharmaceutically acceptable salts thereof. Methods of using said compounds and pharmaceutical...
2016/0361374 USE OF A CASEIN HYDROLYSATE AS AN ANTIVIRAL AGENT
The present invention relates to the use of a casein hydrolysate as an antiviral agent for the treatment of opportunistic virus infections, especially...
2016/0361373 Methods of Extraction of Nitrosylated or Nitrated Derivatives of Ascorbic Acid from Myriciaria Dubia and...
The present invention relates to methods and strategies for extracting nitrosylated and/or nitrated derivatives and analogs from Myriciaria dubia fruit and for...
2016/0361372 USE OF RHODIOLA CRENULATA EXTRACT VIA THE TOPICAL ROUTE
The invention relates to the use of a Rhodiola crenulata extract, via the topical route, for increasing the energy metabolism of the cutaneous tissues of a...
2016/0361371 GARCINIA MANGOSTANA COMPOSITION, MEDICATION AND HEALTH FOOD INCLUDING THE SAME
A Garcinia mangostana composition, a medication and a health food including the same for enhancing learning ability and memory of a patient with Alzheimer's...
2016/0361370 METHOD TO PREPARE HIRSUTELLA SINENSIS POLYSACCHARIDES POSSESSING PROTECTIVE ACTIVITIES ON FATTY LIVER DISEASE
The present invention provides a method to prepare polysaccharides from Hirsutella sinensis. The prepared polysaccharides can reduce liver size, weight and the...
2016/0361369 NON-PATHOGENIC F18 E. COLI STRAIN AND USE THEREOF
There is provided an isolated E. coli strain deposited at the International Depositary Authority of Canada (IDAC) on Jun. 20, 2013 and attributed accession...
2016/0361368 COMPOSITION COMPRISING BEE PRODUCTS
The present application relates to a composition consisting of honey, beeswax and cocoa butter, characterized by a melting temperature of 36.+-.3.degree. C.,...
2016/0361367 PHARMACOPUNCTURE COMPOSITION FOR EYE HEALTH AND METHOD FOR MANUFACTURING THE SAME
The present invention relates to a pharmacopuncture composition for eye health that includes medicinal materials beneficial to the improvement of eye health...
2016/0361366 AMNION DERIVED ADHERENT CELLS
Provided herein are novel angiogenic cells from amnion, referred to as amnion derived adherent cells, and populations of, and compositions comprising, such...
2016/0361365 TREATMENT OF CNS DISEASE WITH ENCAPSULATED INDUCIBLE CHOROID PLEXUS CELLS
Compositions and methods are disclosed that relate to improved treatments for nervous system diseases and disorders using CNS-implanted semi-permeable...
2016/0361364 IMMUNOMODULATORY COMPOSITIONS
The present invention relates to pharmaceutical compositions comprising mesenchymal cells (MSCs) and additional agents for blocking co-stimulation of the...
2016/0361363 METHOD OF TREATING GRAFT VERSUS HOST DISEASE
A method for preventing the development of or treating GvHD complications in a mammalian patient which comprises administering to the mammal a population of...
2016/0361362 METHOD OF TREATING THE EFFECTS OF STROKE
The present disclosure provides methods of improving cerebral function or preventing loss of cerebral function and/or treating or preventing a movement...
2016/0361361 PHARMACEUTICAL COMPOSITION COMPRISING ERYTHROCYTES ENCAPSULATING A PLP-DEPENDENT ENZYME AND ITS COFACTOR
The invention relates to a pharmaceutical composition containing a PLP-dependent enzyme and optionally its cofactor, pyridoxal phosphate (PLP), and/or a...
2016/0361360 DISEASE THERAPY WITH CHIMERIC ANTIGEN RECEPTOR (CAR) CONSTRUCTS AND T CELLS (CAR-T) OR NK CELLS (CAR-NK)...
The present invention concerns CAR, CAR-T and CAR-NK constructs, preferably comprising a scFv antibody fragment against a disease-associated antigen or a...
2016/0361359 METHOD OF ENGINEERING CHEMOTHERAPY DRUG RESISTANT T-CELLS FOR IMMUNOTHERAPY
The present invention relates to the use of "off-the-shelf" allogeneic therapeutic cells for immunotherapy in conjunction with chemotherapy to treat patients...
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