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Patent # Description
2016/0361358 PHARMACEUTICAL CONTAINING DENDRITIC CELLS, AND METHOD FOR PRODUCING SAME
[Problem] The purpose of the present invention is to provide a novel pharmaceutical for use in cellular immunotherapy for the prevention and/or treatment of...
2016/0361357 STABLE HIGH CONCENTRATION STRONTIUM COMPOUNDS AND FORMULATIONS FOR TOPICAL APPLICATION
The disclosure herein relates to high concentration strontium compounds. The high concentrations are achievable through the use of a specialized polymer. More...
2016/0361356 METHODS, COMPOSITIONS AND ARTICLES OF MANUFACTURE FOR ENHANCING SURVIVABILITY OF CELLS, TISSUES, ORGANS, AND...
The present invention concerns the use of oxygen antagonists and other active compounds for inducing stasis or pre-stasis in cells, tissues, and/or organs in...
2016/0361355 SODIUM NITRITE-CONTAINING PHARMACEUTICAL COMPOSITIONS
Provided herein are pharmaceutically acceptable sodium nitrite and pharmaceutical compositions thereof. Also provided herein are methods for determining the...
2016/0361354 IMMUNE MODULATION USING PEPTIDES AND OTHER COMPOSITIONS
The present invention generally relates to compositions and methods for topical or transdermal delivery for immune modulation. In some cases, the composition...
2016/0361353 NITRIC OXIDE GENERATOR COMBINED WITH PDE5 INHIBITORS
Described herein are compounds and methods of using nitric oxide (NO) generating compositions with a phosphodiesterase inhibitor of a phosphodiesterase that...
2016/0361352 Treatment of Multiple Sclerosis With Combination of Laquinimod and Glatiramer Acetate
This invention provides a method of treating a patient afflicted with multiple sclerosis or presenting a clinically isolated syndrome comprising administering...
2016/0361351 ABSORBENT INGESTIBLE AGENTS AND ASSOCIATED METHODS OF MANUFACTURE AND USE
Appetite suppression and weight management achieved through pre-meal ingestion of temporary gastric bulking agents in the form of superabsorbent polymer...
2016/0361350 POLYMER HYDROGELS AND METHODS OF PREPARATION THEREOF
The invention relates to a method for the preparation of a polymer hydrogel, comprising cross-linking a precursor comprising a hydrophilic polymer optionally...
2016/0361349 APPLICATIONS OF PARTIALLY AND FULLY SULFATED HYALURONAN
Described herein is the use of partially and fully sulfated hyaluronan or the pharmaceutically acceptable salt or ester thereof for therapeutic and cosmetic...
2016/0361348 METHOD TO PREPARE HIRSUTELLA SINENSIS POLYSACCHARIDES POSSESSING ANTI-OBESITY PROPERTIES AND USES THEREOF
The present invention provides a method to prepare polysaccharides from Hirsutella sinensis. The prepared polysaccharides reduce body weight and fat...
2016/0361347 MATERIALS FOR TREATING AND PREVENTING MUCOSA RELATED DISEASE
Provided is a hyaluronic acid (HA) composition for use in treating or preventing mucosa related disorders or diseases including a mixture of HAs having...
2016/0361346 COMBINATIONS FOR ORAL COMPOSITIONS, THEIR PREPARATION AND USE
A composition having a pH in the range of from 3 to 8.5, comprising: (a) in the range of from 0.1% to <10% w/w (based on the total weight of the...
2016/0361345 Hydroxypropyl Beta-Cyclodextrin Compositions and Methods
This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally...
2016/0361344 COMPOSITIONS BASED ON METHYL CYCLODEXTRINS FOR THE TREATMENT AND/OR PREVENTION OF DISEASES BY INCREASING THE...
The invention relates to a novel use of a pharmaceutical composition comprising at least one methyl cyclodextrin having a molar substitution (MS) degree of...
2016/0361343 SEPSIS TREATMENT AND RELATED COMPOSITIONS METHODS AND SYSTEMS
Provided herein are methods and systems and related compositions comprising an effective amount of one or more zwitterionic polysaccharide possibly in...
2016/0361342 USE OF ALGINATE OLIGOMERS IN THE TREATMENT OF CYSTIC FIBROSIS AND OTHER CONDITIONS ASSOCIATED WITH DEFECTIVE...
A method is for the treatment of a condition in a human patient arising from or associated with a defective cystic fibrosis transmembrane conductance regulator...
2016/0361341 METHOD TO PREPARE HIRSUTELLA SINENSIS POLYSACCHARIDES POSSESSING INSULIN-SENSITIZING PROPERTIES AND...
The present invention provides a method to prepare polysaccharides from Hirsutella sinensis. The prepared polysaccharides can reduce hyperglycemia and insulin...
2016/0361340 TREATMENT OF CARDIAC DISEASES WITH MODULATORS OF THE HIPPO PATHWAY
The present invention provides methods of treating and preventing cardiac hypertrophy and heart failure. Further provided are transgenic animals exhibiting...
2016/0361339 PHARMACOKINETICS OF S-ADENOSYLMETHIONINE FORMULATIONS
Compositions and methods to improve the pharmacokinetic profile of S-Adenosylmethionine (SAMe) are provided, as are methods of treating various disorders using...
2016/0361338 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF
The present application relates to compositions comprising selenium compounds, such as 5'-Methylselenoadenosine, Se-Adenosyl-L-homocysteine, ...
2016/0361337 FORMULATIONS OF ACADESINE
This invention provides a buffered solution comprising acadesine, as well as compositions, formulations and kits containing said solution. The solution,...
2016/0361336 INJECTABLE ANTIBIOTIC FORMULATIONS AND USE THEREOF
Provided herein are pharmaceutically acceptable compositions containing macrolide antibiotics, in particular azithromycin. In particular, compositions...
2016/0361335 Rapidly Dispersible Dosage Form of Topiramate
A taste-masked rapidly dispersible dosage form of topiramate is provided. Wax coated particles of topiramate are included within a porous bound matrix. The...
2016/0361334 APPLICATION OF BAICALIN IN PREPARATION OF DRUG FOR TREATING RICIN POISONING
Provided is an application of baicalin in preparation of a drug for treating ricin poisoning. A Hela cytoprotection test and a mouse ricin poisoning model have...
2016/0361333 USE OF CITRUS POLYPHENOL FOR WOUND HEALING AND COMPOSITION THEREOF
The present invention provides a composition for wound healing, which includes an effective amount of a citrus polyphenol. Moreover, the present invention also...
2016/0361332 HETEROBIFUNCTIONAL PAN-SELECTIN INHIBITORS
Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their...
2016/0361331 EQUOL CONCENTRATION INCREASING AGENT CONTAINING PSICOSE AS ACTIVE INGREDIENT
The present invention relates to a processed food composition containing, as an active ingredient, psicose, which is a saccharide having the function of...
2016/0361330 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS
Provided are compounds, methods, and pharmaceutical compositions for treating Filoviridae virus infections by administering ribosides, riboside phosphates and...
2016/0361329 COMPOUNDS FOR TREATMENT OF COMPLEMENT MEDIATED DISORDERS
Compounds, methods of use, and processes for making inhibitors of complement factor D comprising Formula I, or a pharmaceutically acceptable salt or...
2016/0361328 SALTS OF PRODRUGS OF PIPERAZINE AND SUBSTITUTED PIPERIDINE ANTIVIRAL AGENTS
This invention provides for prodrug Compounds I, pharmaceutical compositions thereof, and their use in treating HIV infection. ##STR00001## wherein: X is C or N...
2016/0361327 FORMULATIONS FOR PHARMACEUTICAL AGENTS
Described herein are processes for improving the aqueous availability of poorly soluble bioactive materials and bioactive compounds and compositions formed by...
2016/0361326 METHOD OF TREATING HYPERGLYCEMIA AND DIABETES AND OF INCREASING ADSORPTION AND EFFICACY OF VITAMIN D
A pharmaceutical for and a method of treating one of vitamin D deficiency, diabetes and pre-diabetes in an animal comprising the steps A method of treating one...
2016/0361325 TOPICAL FORMULATIONS COMPRISING A STEROID
The application provides formulations for the topical administration of an active agent comprising at least one steroid, in the form of topical sprays that are...
2016/0361324 METHOD OF TREATING MIDDLE EAR INFECTIONS
Aqueous suspension formulations containing dexamethasone and ciprofloxacin are disclosed for the treatment of middle ear infections in human patients having an...
2016/0361323 PHARMACEUTICAL COMPOSITIONS CONTAINING TESTOSTERONE AND AN AROMATASE INHIBITOR
An implant comprising testosterone or an ester thereof and an aromatase inhibitor; the aromatase inhibitor may be selected from the group consisting of...
2016/0361322 COMPOSITION AND METHOD FOR ORAL DELIVERY OF ANDROGEN PRODRUGS
Provided oral testosterone undecanoate compositions can be administered to hypogonadal males with a meal without the fat content of the meal substantially...
2016/0361321 STABLE TRANSDERMAL TESTOSTERONE GEL
The present invention relates to a stable transdermal gel composition comprising Testosterone, a penetration enhancer, a gelling agent with pharmaceutically...
2016/0361320 SOFT LOZENGES COMPRISING CORTICOSTEROIDS
Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising non-systemic corticosteroid soft...
2016/0361319 METHODS OF TREATING DISORDERS ASSOCIATED WITH PROTEIN AGGREGATION
The present invention relates to methods of treatment of clinical disorders associated with protein aggregation comprising administering, to a subject, an...
2016/0361318 COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION
The invention relates to classes of pharmaceutically-active heterocyclic compounds and pharmaceutically acceptable salts, and hydrates thereof, and...
2016/0361317 COMPOSITIONS COMPRISING RANK/RANKL ANTAGONISTS AND RELATED COMPOUNDS FOR TREATING PAIN
Disclosed herein are methods of treating pain using RANK/RANKL antagonists.
2016/0361316 NOVEL HETEROCYCLES AS MODULATORS OF KINASE ACTIVITY
The invention provides novel heterocyclic amines according to Formula (I) their manufacture and use for the treatment of hyperproliferative diseases, such as...
2016/0361315 IBRUTINIB PRODRUGS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE
Prodrugs of ibrutinib, pharmaceutical compositions comprising the prodrugs, and methods of using the prodrugs and pharmaceutical compositions for treating...
2016/0361314 COMBINATION OF AN ALK INHIBITOR AND A CDK INHIBITOR FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES
The present invention relates to a pharmaceutical combination comprising, separately or together, (1) a first agent which is an ALK inhibitor or a ...
2016/0361313 PHARMACEUTICAL COMPOSITIONS
The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the...
2016/0361312 CERTAIN KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF
Certain chemical entities are provided herein. Also provided are pharmaceutical compositions comprising at least one chemical entity and one or more...
2016/0361311 LIGANDS THAT TARGET HEPATITIS C VIRUS E2 PROTEIN
Hepatitis C Virus (HCV) infects 200 million individuals worldwide. Although several FDA approved drugs targeting the HCV serine protease and polymerase have...
2016/0361310 PHARMACEUTICAL COMPOUNDS
This invention relates to compounds that inhibit or modulate the activity of Chk-1 kinase. Also provided are pharmaceutical compositions containing the...
2016/0361309 METHODS OF TREATING CANCER PATIENTS RESPONDING TO EZH2 INHIBITOR GSK126
Disclosed herein are methods of treating cancer in a human, where the methods include determining at least one of the following in one or more samples from the...
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