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Patent # Description
2016/0362508 FLUOROPOLYMER COMPOSITIONS AND PURIFICATION METHODS THEREOF
Described herein is a method of purifying a product and recycling water comprising the following steps: (i) providing a crude product comprising at least one...
2016/0362507 DUAL-CURE CATIONICALLY POLYMERISABLE COMPOSITION AND METHOD FOR PRODUCING A COATING OR A COMPOSITE MATERIAL...
In a first aspect, the present invention concerns a kit for a polymerisable composition comprising a portion A constituted by a composition comprising at least...
2016/0362506 Process for Continuous Solution Polymerization
Described herein are methods for continuous solution polymerization. The method may comprise polymerizing one or more monomers and comonomers in the presence...
2016/0362505 PROCESS FOR THE PRODUCTION OF MODIFIED BUTYL RUBBER
There is provided a process for producing an ionomer comprising the steps of (a) admixing in a mixer a halogenated copolymer with at least one nitrogen and/or...
2016/0362504 DIENE ELASTOMER MODIFIED BY COUPLING HAVING SILANOL FUNCTIONS, SYNTHESIS METHOD FOR SAME, AND RUBBER...
The present invention relates to a modified diene elastomer predominantly comprising a species coupled via a group bearing a function comprising a silicon atom...
2016/0362503 NEW ENAMEL-DENTIN ADHESIVES BASED ON CHEMICALLY MODIFIED NATURAL POLYSACCHARIDES
The present invention concerns the preparation of chemically modified derivatives of chitosan with acrylic groups and their use in the field of enamel-dentin...
2016/0362502 PHOSPHONATED POLYSACCHARIDES AND GELS AND PROCESS FOR MAKING SAME
Products and processes that are related to phosphonated polysaccharide compositions, including phosphonated polysaccharide gels, having a substituent degree of...
2016/0362501 Methods, compositions and kits for treating a subject using a recombinant heteromultimeric neutralizing binding...
Methods, compositions and kits are provided for treating a subject exposed to or at risk for exposure to a disease agent using a pharmaceutical composition...
2016/0362500 Removal of target cells by circulating virus-specific cytotoxic T-cells using MHC class I comprising complexes
The invention comprises a complex comprising as first part an antibody derived part that specifically binds to a target antigen, and as second part a...
2016/0362499 Polynucleotides Encoding VEGF/DLL4 Binding Agents
The present invention relates to VEGF-binding agents, DLL4-binding agents, VEGF/DLL4 bispecific binding agents, and methods of using the agents for treating...
2016/0362498 ANTIBODY SPECIFICALLY BINDING TO GLP-1R AND FUSION PROTEIN THEREOF WITH GLP-1
Disclosed in the present invention is an antibody specifically binding to GLP-1R and a fusion protein thereof with GLP-1. The fusion proteins can effectively...
2016/0362497 HIGH AFFINITY ANTIBODY ANTAGONISTS OF INTERLEUKIN-13 RECEPTOR ALPHA 1
High affinity antibody antagonists of human interleukin-13 receptor alpha 1 are disclosed. The antibody molecules are effective in the inhibition of...
2016/0362496 MONOCLONAL ANTIBODIES TO FIBROBLAST GROWTH FACTOR RECEPTOR 2
The present invention is directed toward a monoclonal antibody to fibroblast growth factor receptor 2, a pharmaceutical composition comprising same, and...
2016/0362495 Human Monoclonal Antibodies to Programmed Death Ligand 1 (PD-L1)
The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies that specifically hind to PD-L1 with high affinity....
2016/0362494 ICOS BINDING PROTEINS
The present invention relates to an ICOS binding protein or antigen binding portion thereof that is an agonist to human ICOS and does not induce complement,...
2016/0362493 GLYCAN-MODIFIED ANTI-CD4 ANTIBODIES FOR HIV PREVENTION AND THERAPY
Disclosed herein are glycan-modified anti-CD4 monoclonal antibodies with N-linked glycans attached to the variable region. Expression vectors and cell lines...
2016/0362492 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PERSISTENT INFECTIONS AND CANCER BY INHIBITING THE PROGRAMMED...
The present invention provides methods and compositions for the treatment, prevention, or reduction of persistent infections, such as chronic infections,...
2016/0362491 BISPECIFIC MOLECULE BINDING TLR9 AND CD32 AND COMPRISING A T CELL EPITOPE FOR TREATMENT OF ALLERGIES
A molecule or molecule complex capable of binding to TLR9 and to CD32 comprising at least one epitope of at least one antigen, its production and its use a...
2016/0362490 ANTI-CD33 ANTIBODIES AND METHODS FOR TREATMENT OF ACUTE MYELOID LEUKEMIA USING THE SAME
The present invention relates to antibodies that bind CD33. More particularly, the invention relates to anti-CD33 antibodies, fragments and homologues of these...
2016/0362489 Treatment of PD-L1-Positive Melanoma Using an Anti-PD-1 Antibody
The invention provides a method of treating a melanoma comprising (i) identifying a patient having a PD-L1 positive melanoma and (ii) administering to the...
2016/0362488 ANTI-PACAP ANTIBODIES AND USES THEREOF
The present invention is directed to antagonistic antibodies and antigen binding fragments thereof having binding specificity for PACAP. These antibodies...
2016/0362487 Anti-IL-33 Antibodies and Uses Thereof
The present invention provides antibodies that bind to interleukin-33 (IL-33) and methods of using the same. The invention includes antibodies that inhibit or...
2016/0362486 SELF-BUFFERING PROTEIN FORMULATIONS
The invention herein described, provides, among other things, self-buffering protein formulations. Particularly, the invention provides self-buffering...
2016/0362485 SELF-BUFFERING PROTEIN FORMULATIONS
The invention herein described, provides, among other things, self-buffering protein formulations. Particularly, the invention provides self-buffering...
2016/0362484 SELF-BUFFERING PROTEIN FORMULATIONS
The invention herein described, provides, among other things, self-buffering protein formulations. Particularly, the invention provides self-buffering...
2016/0362483 PROTEIN SUSTAINED-RELEASE INJECTABLE FORMULATION
The present invention provides sustained-release pharmaceutical formulations for administering proteins to the eye. In particular, the invention provides...
2016/0362482 COMPOSITIONS AND METHODS OF MODULATING B CELL RESPONSE
A method of treating a B cell mediated disorder in a subject in need thereof, the method includes administering to B cells of the subject at least one agent...
2016/0362481 COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF INFLAMMATORY BOWEL DISEASE
Compositions and methods for the therapy and diagnosis of Inflammatory Bowel Disease (IBD), including Crohn's Disease and Ulcerative Colitis, are disclosed....
2016/0362480 NOVEL OPRF/I FUSION PROTEINS, THEIR PREPARATION AND USE
The present invention relates to a novel trimeric OprF/I fusion protein comprising a portion of the Pseudomonas aeruginosa outer membrane protein F which is...
2016/0362479 Broadly Neutralizing Monoclonal Antibodies Against HIV-1 V1V2 Env Region
The present invention relates anti-HIV therapies and prophylaxis. Specifically, the invention relates to broadly neutralizing antibodies against HIV-1, nucleic...
2016/0362478 CD4-MIMETIC SMALL MOLECULES SENSITIZE HUMAN IMMUNODEFICIENCY VIRUS TO VACCINE-ELICITED ANTIBODIES
Described herein are methods of generating a protein binding domain that specifically binds to gp120 in a specific conformational state, comprising contacting...
2016/0362477 SECRETORY IGA COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE THEREOF
Described herein is secretory IgA isolated from the intestinal luminal fluid and intestinal mucosal of animals such as pigs and cows. Also included are methods...
2016/0362476 METHODS AND COMPOSITIONS FOR PRODUCING A CHIMERIC POLYPEPTIDE
The present invention provides methods and compositions for converting a first polypeptide into a chimeric polypeptide. The invention includes two vectors: a...
2016/0362475 UTI FUSION PROTEINS
The present invention provides UTI fusion proteins, DNA sequences for producing the same, and pharmaceutical compositions and methods of using the same.
2016/0362474 IMMUNOGLOBULIN FUSION PROTEINS AND USES THEREOF
A fusion protein is disclosed. The fusion protein of the invention comprises an Fc fragment of an immunoglobulin G and a bioactive molecule, wherein the Fc is...
2016/0362473 IMMUNOGLOBULIN FUSION PROTEINS AND USES THEREOF
A fusion protein is disclosed. The fusion protein of the invention comprises an Fc fragment of an immunoglobulin G and a bioactive molecule, wherein the Fc is...
2016/0362472 CD20 THERAPIES, CD22 THERAPIES, AND COMBINATION THERAPIES WITH A CD19 CHIMERIC ANTIGEN RECEPTOR (CAR)-...
The invention provides compositions and methods for treating diseases associated with expression of CD19, e.g., by administering a recombinant T cell...
2016/0362471 SHORTENED CD95-FC VARIANTS
The present invention relates to an isolated fusion protein comprising an extracellular CD95 domain or a functional fragment thereof and an Fc domain or...
2016/0362470 Recombinant Fusion Proteins and Libraries from Immune Cell Repertoires
Disclosed herein are methods and compositions for generating a repertoire of recombinant fusion polypeptides from immune cells, and uses thereof.
2016/0362469 Methods for protein modification in pharmaceutical applications
The current invention discloses methods to modify protein for pharmaceutical applications and reagents to treat disease such as pathogen infection and cancer....
2016/0362468 NATRIURETIC POLYPEPTIDES
This document provides methods and materials related to natriuretic polypeptides and the use of natriuretic polypeptides to treat cardiovascular and/or renal...
2016/0362467 APRIL VARIANTS
The present invention provides a variant proliferation-inducing ligand (APRIL), which has a higher binding affinity to BCMA than wild-type APRIL; and/or...
2016/0362466 PEPTIDES HAVING OSTEOBLAST GROWTH-PROMOTING ACTIVITY AND USE THEREOF
The present invention provides a novel peptide having bone formation-promoting effect and chondrocyte growth-promoting effect, in particular, a peptide having...
2016/0362465 WT1 ANTIGENIC POLYPEPTIDE, AND ANTI-TUMOR AGENT CONTAINING SAID POLYPEPTIDE
[Problem] To provide a polypeptide which enables stimulation of numerous T cells of different derivation, and to induce strong immunological response against...
2016/0362464 NOVEL THERAPEUTIC TARGETS FOR CANCER PROGRESSION
The invention provides DAPLE as a novel regulator of G protein activity and its diagnostic and therapeutic use in cancer.
2016/0362463 Pharmaceutical composition inhibiting interaction between MZF-1 and Elk-1
This invention discloses a peptide, which inhibits the interaction between of MZF-1 and Elk-1 and further inhibits cancers. Both myeloid zinc finger 1 (MZF-1)...
2016/0362462 Modification and Novel Compositions of Human Secretoglobin Proteins
Novel compositions of recombinant human CC10 protein have been generated by chemically modifying the pure protein in vitro. Several new synthetic preparations...
2016/0362461 KIDNEY DISEASE TARGETS AND USES THEREOF
The present invention provides a method for diagnosing and detecting diseases associated with kidney. The present invention provides one or more proteins or...
2016/0362460 MULTI-SPECIFIC POLYPEPTIDE USEFUL FOR LOCALIZED TUMOR IMMUNOMODULATION
The disclosure provides a multi-specific polypeptide with a first moiety specific for a tumor-associated antigen on tumor cell surface and a second moiety...
2016/0362459 ANTIMICROBIAL PEPTIDES
The invention provides a peptide comprising: a core amino acid sequence, which is identical or similar to the amino acid sequence of a member of the Cecropin...
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