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Patent # Description
2016/0375054 Microporous Zirconium Silicate for the Treatment of Hyperkalemia
The present invention relates to novel microporous zirconium silicate compositions that are formulated to remove toxins, e.g. potassium ions, from the...
2016/0375053 Use of the mixture of a salt and sugar in the manufacture of a medicament employed for treating lax vagina...
The use of the mixture of a salt and sugar in the manufacture of a medicament employed for treating lax vagina syndrome or colpoxerosis disease in a mammal....
2016/0375052 COMPOSITIONS AND METHODS FOR TREATMENT OF SHORT TELOMERE DISORDERS
The invention generally relates to methods of treating short telomere disorders using known compounds and pharmaceutical compositions comprising same. More...
2016/0375051 AGENT FOR THE TREATMENT OF SKIN CONDITIONS
Disclosed are methods of treatment and compositions containing at least one non-volatile silicone oil in combination with at least one spreading agent for use...
2016/0375050 METHODS AND COMPOSITIONS INVOLVING CHITOSAN NANOPARTICLES
Disclosed are nanoparticles for the delivery of a therapeutic agent or a diagnostic agent to a subject that include a chitosan and a polyphosphate, wherein the...
2016/0375049 COMPOSITIONS
The present invention relates to administration of a dinucleoside polyphosphate analogue or a pharmaceutically acceptable salt thereof, topically in a...
2016/0375048 SUSTAINED-RELEASE FORMULATIONS OF TOPIRAMATE
Pharmaceutical compositions of topiramate for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an...
2016/0375047 SUSTAINED-RELEASE FORMULATIONS OF TOPIRAMATE
Pharmaceutical compositions of topiramate for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an...
2016/0375046 METHOD FOR TREATMENT OF DISEASE WITH PURE PORCINE MONOSIALOGANGLIOSIDE GM1
A process for preparing pure monosialoganglioside GM1 in the form of its sodium salt. There is provided a process for the isolation and purification of...
2016/0375045 VAGINAL COMPOSITION AND USE THEREOF
A use of isomaltulose in the preparation of a vaginal composition, wherein the amount of isomaltulose used is 0.05-20% (w/w). A vaginal composition contains...
2016/0375044 Compositions and Methods for Inhibiting Arginase Activity
The invention relates to methods of treating cancer, with a combination of an arginase inhibitor and a chemotherapeutic agent. The invention further relates to...
2016/0375043 CONCENTRATED THERAPEUTIC PHOSPHOLIPID COMPOSITIONS
The invention relates to concentrated therapeutic phospholipid compositions; methods for treating or preventing diseases associated with cardiovascular...
2016/0375042 USE OF CAMPTOTHECIN DERIVATIVE IN PREPARING PHARMACEUTICAL USED FOR TREATING MULTIPLE MYELOMA
The present invention relates to use of a camptothecin derivative for preparing a medicament for the treatment of multiple myeloma. The medicament is...
2016/0375041 INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT AUTOIMMUNE DISORDERS
The invention provides methods and pharmaceutical compositions that can treat autoimmune disease by reducing the production of pyrophosphate intermediates...
2016/0375040 TOPICAL COMPOSITION WITH VITAMIN D3
The topical composition with Vitamin D3 includes Vitamin D3, one or more aromatic oils, and aloe vera gel. Vitamin D3 is soluble in aromatic oils, and aloe...
2016/0375039 COMPOUNDS FOR THE TREATMENT OF OBESITY AND METHODS OF USE THEREOF
Weight loss agents include compounds defined by Formula I or a pharmaceutically acceptable salt or prodrug thereof, compositions containing the same, and...
2016/0375038 HORMONE TREATMENT FOR AGE-RELATED HEARING LOSS-PRESBYCUSIS
Permanent hearing loss or deafness affects about 15% of people worldwide, about 40 million in the US alone. There are currently no FDA-approved drugs on the...
2016/0375037 NON-HORMONAL STEROID MODULATORS OF NF-KAPPA BETA FOR TREATMENT OF DISEASE
The present invention relates to compounds and methods which may be useful as treatments of diseases.
2016/0375036 PROLIPOSOMAL TESTOSTERONE FORMULATIONS
Novel testosterone formulations are disclosed where testosterone is incorporated into a phospholipid/cholesterol system to produce a proliposomal powder...
2016/0375035 CHROMIUM HISTIDINATE AND CHROMIUM PICOLINATE COMPLEXES
This present disclosure generally relates to the discovery that chromium histidinate (CrHis) and chromium picolinate (CrPic) can exist as complexes in multiple...
2016/0375034 BISMUTH-THIOLS AS ANTISEPTICS FOR BIOMEDICAL USES, INCLUDING TREATMENT OF BACTERIAL BIOFILMS AND OTHER USES
Compositions and methods, including novel homogeneous microparticulate suspensions, are described for treating natural surfaces that contain bacterial biofilm,...
2016/0375033 METHODS OF TREATMENT WITH TASELISIB
Taselisib (GDC-0032) induces the degradation of mutant-p110 alpha protein. Methods for selecting patients with mutant PI3K tumors for treatment with taselisib...
2016/0375032 METHOD OF TREATING NON-SMALL-CELL LUNG CANCER USING PHARMACEUTICAL FORMULATION CONTAINING...
A method of treating non-small cell lung cancer in a mammal by administering to a patient a pharmaceutically acceptable amount of a compound being a...
2016/0375031 ALPHA-OXOACYL AMINO-CAPROLACTAM DERIVATIVE
The purpose of the present invention is to provide a pharmaceutical composition that is useful for the treatment of diseases that are caused by an increase in...
2016/0375030 ERK INHIBITORS
The present invention provides thieno[2,3-c]pyrrol-4-one compounds that inhibit activity of extracellular-signal-regulated kinase (ERK) and may be useful in...
2016/0375029 USE OF NOVEL AUTOPHAGY INHIBITORS TO TREAT AUTOPHAGY RELATED HUMAN DISEASES
Methods of treating autophagy related diseases, e.g. cancer and malaria, using novel autophagy inhibiting agents are described.
2016/0375028 ORGANIC COMPOUNDS
The present invention relates to a new use of phosphodiesterase 1 (PDE1) inhibitors for the treatment of psychosis, schizophrenia, schizoaffective disorder,...
2016/0375027 PROTEIN KINASE INHIBITORS
The present invention relates to a novel family of inhibitors of protein kinase of formula 1 and process for their production and pharmaceutical compositions...
2016/0375026 PYRROLOPYRIMIDINE COMPOUNDS AS KINASE INHIBITORS
Disclosed herein are methods of using pyrrolo[2,3-d]pyrimidine Btk inhibitors, alone or in combination with other therapeutic agents, for the treatment of...
2016/0375025 HUMAN PAPILLOMA VIRUS AS PREDICTOR OF CANCER PROGNOSIS
Methods of treating a head and neck cancer are disclosed.
2016/0375024 COMBINATION THERAPY COMPRISING AN INHIBITOR OF JAK, CDK, AND PIM
The present invention relates to a pharmaceutical combination which comprises (a) a JAK inhibitor compound, (b) a CDK inhibitor, and (c) a PIM kinase inhibitor...
2016/0375023 NOVEL FGFR3 FUSION
The present invention aims to elucidate a polynucleotide as a novel responsible gene for cancer and aims to thus provide a method for detecting the...
2016/0375022 sGC STIMULATORS
Compounds of Formulae I' and I are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds...
2016/0375021 REVERSE AMIDE COMPOUNDS AS PROTEIN DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF
The present invention relates to novel "reverse amide" compounds comprising a zinc chelator group, and the use of such compounds in the inhibition of HDAC6 and...
2016/0375020 USE OF A STATIN COMPOUND AS TOPICAL DRUG FOR TREATING OBESITY, DIABETES, HYPERTENSION AND HYPERLIPEMIA
The invention discloses a use of a statin compound in the preparation of local drugs for improving lipid metabolism and treating obesity, hypertension,...
2016/0375019 TREATMENT OF CHRONIC GRAFT VERSUS HOST DISEASE WITH SYK INHIBITORS
The present disclosure provides methods of utilizing Syk inhibiting compounds in the treatment for graft versus host disease (GVHD) in a human, including acute...
2016/0375018 METHOD OF PREPARING VERY SLIGHTLY SOLUBLE DRUG WITH SOLID DOSAGE FORM
A method of preparing a very slightly soluble drug with solid composition includes the following steps: (a) adding a very slightly soluble drug into an organic...
2016/0375017 Solid Pharmaceutical Compositions for Treating HCV
The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition...
2016/0375016 METHODS FOR REDUCING ANXIETY AND IMPULSIVITY IN SUBJECTS INITIATING TREATMENT WITH SEROTONIN REUPTAKE INHIBITORS
The present invention provides compositions and uses thereof for reducing anxiety and/or impulsivity, including, for example, suicidality, in a subject...
2016/0375015 PHARMACEUTICAL COMPOSITIONS
Methods and compositions are provided which comprise effective amounts of an analgesic to treat a subject, including reducing or eliminating an adverse effect...
2016/0375014 PHARMACEUTICAL COMPOSITIONS
Pharmaceutical compositions are provided which comprise effective amounts of an analgesic to treat a subject, including to reduce or eliminate an adverse...
2016/0375013 PHARMACEUTICAL COMPOSITIONS
Pharmaceutical compositions are provided which comprise effective amounts of an analgesic to treat a subject, including to reduce or eliminate an adverse...
2016/0375012 Compositions and Methods for Increasing the Metabolic Lifetime of Dextromethorphan and Related Pharmacodynamic...
This disclosure relates to methods administering various compounds in conjunction with dextromethorphan to a human being. Dosage forms, drug delivery systems,...
2016/0375011 Pharmaceutical Composition
Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist,...
2016/0375010 ABUSE-RESISTANT PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF OPIOID DEPENDENCE
There is provided pharmaceutical compositions for the treatment of e.g. opioid dependency comprising microparticles of a pharmacologically-effective amount of...
2016/0375009 OLIGOMER-OPIOID AGONIST CONJUGATES
The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when ...
2016/0375008 BUPROPION AS A MODULATOR OF DRUG ACTIVITY
Dosage forms, drug delivery systems, and methods related to sustained release of dextromethorphan or improved therapeutic effects are disclosed. Typically,...
2016/0375007 Nalmefene for Reduction of Alcohol Consumption in Specific Target Populations
The present invention relates to nalmefene for use in the reduction of alcohol consumption in a patient with alcohol dependence who has a high drinking risk...
2016/0375006 USES OF PARALOG-SELECTIVE INHIBITORS OF GSK3 KINASES
The present disclosure provides methods of using GSK3.alpha.-selective inhibitors for treating Fragile X syndrome, attention deficit hyperactivity disorder...
2016/0375005 BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2
The present invention relates to new benzoquinoline inhibitors of vesicular monoamine transporter 2 (VMAT2), pharmaceutical compositions thereof, and methods...
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