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Patent # Description
2016/0375004 Methods for Treating Pancreatic Cancer Using Combination Therapies
Provided are methods for treating pancreatic cancer in a patient by administering liposomal irinotecan (MM-398) alone or in combination with additional...
2016/0375003 DRUG TREATMENT OF OVERACTIVE BLADDER
Provided are methods of treating an overactive bladder in a patient which include: administering a Myosin II ATPase inhibitor compound; or administering an X...
2016/0375002 COMBINATION OF CHECKPOINT KINASE I INHIBITORS AND WEE I KINASE INHIBITORS
A combination of a CHK1 inhibitor and a WEE1 inhibitor are provided.
2016/0375001 MUSCARINIC COMBINATIONS AND THEIR USE FOR COMBATING HYPOCHOLINERGIC DISORDERS OF THE CENTRAL NERVOUS SYSTEM
A combination of a muscarinic cholinergic receptor agonist, a non-anticholinergic antiemetic agent and a non-selective, peripheral anticholinergic agent for...
2016/0375000 PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF MENTAL DISEASE WITH ENHANCED NMDAR FUNCTION
The present invention relates to a pharmaceutical composition for improving a sociability behavior in a patient having a mental disease with an enhanced NMDAR...
2016/0374999 RIFAXIMIN
Amorphous rifaximin, methods of making it, and pharmaceutical compositions containing it. Also described are methods of converting amorphous rifaximin to...
2016/0374998 MACROLIDE PARTICULATES, METHODS FOR PREPARATION, AND MEDICAL DEVICES ASSOCIATED THEREWITH
The disclosure provides macrolide particulates including a macrolide therapeutic agent such as rapamycin at high concentration in the particulate. In one...
2016/0374997 ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS
An aminoacylation/translation (AIT) system based on the protein synthesis system from the pathogen Pseudomonas aeruginosa, was used to screen chemical...
2016/0374996 HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE
The present disclosure relates to compounds effective as human protein tyrosine phosphatase beta (HPTP-.beta.) inhibitors thereby regulating angiogenesis. The...
2016/0374995 Pharmaceutical Compositions
The present invention relates to pharmaceutical compositions useful for administration for treating, preventing, or reducing the risk of microbial infections.
2016/0374994 PARASITICIDAL ORAL VETERINARY COMPOSITIONS COMPRISING SYSTEMICALLY-ACTING ACTIVE AGENTS, METHODS AND USES THEREOF
This invention relates to oral veterinary compositions for combating ectoparasites and endoparasites in animals, comprising at least one systemically-acting...
2016/0374993 TREATMENT OF GOUT
Sodium 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylt- hio) acetate is described. In addition, pharmaceutical compositions and uses such...
2016/0374992 COSMETIC PRESERVATIVES AS THERAPEUTIC CORNEOSCLERAL TISSUE CROSS-LINKING AGENTS
A method of cross-linking collagen present in a collagenous tissue comprising contacting the collagenous tissue with an amount of a formaldehyde releasing...
2016/0374991 AUTOTAXIN INHIBITOR COMPOUNDS
Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such...
2016/0374990 DIARYL AND ARYLHETEROARYL UREA DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE...
The present invention relates to certain pyrazole derivatives of Formula (I) and pharmaceutical compositions thereof that modulate the activity of the...
2016/0374989 METHODS AND COMPOSITIONS ASSOCIATED WITH THE GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR
Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor...
2016/0374988 SHP2 INHIBITORS AND METHODS OF TREATING AUTOIMMUNE AND/OR GLOMERULONEPHRITIS-ASSOCIATED DISEASES USING SHP2...
Methods are disclosed herein for administering a oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitor for treating...
2016/0374987 TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH NEBULIZED BETA 2-AGONIST OR COMBINED NEBULIZED BETA...
Inhalation solutions for administration of beta 2-agonists or combinations of muscarinic antagonists and beta 2-agonists for the treatment of breathing...
2016/0374986 PPARs AGONIST ACTIVITY ENHANCING DRUG
A lifestyle disease improving drug is disclosed that enhances PPAR.alpha., .delta. and .gamma. agonist activities that includes a compound having the lactone...
2016/0374985 Bioactivity proanthocyanidin compound isolated from Lasia spinosa (L.) Thwait
The present invention disclosed a compound, proanthocyanidin A1 (PA1), which is isolated from Lasia spinosa (L.) Thwait, for its effects in shortening of...
2016/0374984 NANOPARTICLE ISOFLAVONE COMPOSITIONS & METHODS OF MAKING AND USING THE SAME
The present invention is directed to formulations of genistein and methods for making and using the same. In particular embodiments, the formulations described...
2016/0374983 COMBINATION OF ROCAGLAMIDE AND APOPTOSIS INDUCING SUBSTANCES FOR THE TREATMENT OF CANCER
The present invention relates to a combined preparation comprising at least one rocaglamide derivative and at least one apoptosis inducing agent, preferably...
2016/0374982 SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF
The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart...
2016/0374981 ANORECTIC AGENT
A method of increasing blood cholecyctokinin level is described. The method includes administering to a subject in need of increasing blood cholecyctokinin...
2016/0374980 TRIHEPTANOIN FOR THE TREATMENT OF GLUCOSE TRANSPORT 1 DEFICIENCY
Provided are methods for treating GLUT1 and related brain energy deficiencies comprising administering odd-carbon fatty acid sources, e.g., C5 or C7 fatty acid...
2016/0374979 Method of Treatment of Alopecia with Monoterpenoids
The present application generally relates to topical formulations comprising monoterpenoid compounds which are effective inhibitors of FGF-5-dependent...
2016/0374978 ANTIMICROBIAL COMPOSITIONS COMPRISING GLYCERYL NITRATES
Provided are antimicrobial solutions comprising a glyceryl nitrate (e.g., glyeryl trinitrate) in combination with a chelator (e.g., citrate), a peroxide, a...
2016/0374977 Composition for Treatment of Mold
A composition and method of treating patients diagnosed with NAFLD is disclosed. The composition contains n-3 polyunsaturated fatty acids (PUFAs) for treatment...
2016/0374976 EICOSAPENTAENOIC ACID-PRODUCING MICROORGANISMS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and...
2016/0374975 COMPOSITION FOR TREATMENT OF NAFLD
A composition and method of treating patients diagnosed with NAFLD is disclosed. The composition contains n-3 polyunsaturated fatty acids (PUFAs) for treatment...
2016/0374974 SERINE GLYCEROPHOSPHOLIPID PREPARATION AND METHOD FOR TREATMENT OF SEIZURES
A preparation for treatment and/or prevention of seizures comprising a non-mammalian derived mixture of serine glycerophospholipids (PS) conjugates, wherein...
2016/0374973 SOAP COMPOSITIONS AND METHODS
Natural soap compositions and methods of manufacturing the same having anti-microbial properties for treating and preventing diaper rash and other microbial...
2016/0374972 INTRAVENOUS ADMINISTRATION OF CITRULLINE DURING SURGERY
A method for administering citrulline to a patient during surgery without filtration of the hemolysis.
2016/0374971 DIETARY SUPPLEMENTS FOR TREATING CANCER
Methods and compositions for treating cancer and other disorders associated with undesired cellular proliferation are provided comprising administering to a...
2016/0374970 PHARMACEUTICAL COMPOSITION
A pharmaceutical composition for application in human and animals, with at least one systemically and/or locally acting, topically applicable active ingredient...
2016/0374969 POTASSIUM ION CHANNEL MODULATORS & USES THEREOF
Compounds of formula (I): ##STR00001## and pharmacologically acceptable salts and pro-drugs thereof, wherein the variables are as defined in the specification,...
2016/0374968 BICYCLIC ANALGESIC COMPOUNDS
Analgesic compounds for treatment of pain or fever that include a bicyclopentane moiety linked to an amine, combinations of the compounds with opioid analgesic...
2016/0374967 ORGANIC THIOPHOSPHATE ANTIRETROVIRAL AGENTS
A method for the prevention or treatment of human immunodeficiency virus infection by administering an effective amount of amifostine, phosphonol, or similar...
2016/0374966 EPINEPHRINE NANOPARTICLES, METHODS OF FABRICATION THEREOF, AND METHODS FOR USE THEREOF FOR TREATMENT OF...
The invention provides compositions including epinephrine nanoparticles and methods for therapeutic use of the compositions for the treatment of conditions...
2016/0374965 TAMPER RESISTANT IMMEDIATE RELEASE CAPSULE FORMULATION COMPRISING TAPENTADOL
The invention is directed to an immediate release capsule which mitigates the abuse of Tapentadol or physiologically acceptable salt thereof by direct...
2016/0374964 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF
Described herein are antimicrobial compounds identified via a high-throughput screen to identify compounds that produce anucleate cells in E. coli after cell...
2016/0374963 ABUSE-PROOFED DOSAGE FORM
The invention relates to a dosage that is thermoshaped without being extruded and that is safeguarded from abuse, comprising at least one synthetic or natural...
2016/0374962 MICROSIZED CURCUMIN COMPOSITIONS
Disclosed herein are formulations for the local delivery of therapeutically effective doses of curcumin that provide sufficient serum levels of curcumin to...
2016/0374961 Identification of Stabilizers of Multimeric Proteins
Disclosed herein are compounds and compositions thereof which find use in increasing stability of TTR tetramers reducing its tendency to misfold and form...
2016/0374960 Method of Topically Administering a Curcumin Derivative
The present invention is directed to topically administering a compound represented by Structural Formula (I): ##STR00001## or a pharmaceutically acceptable salt...
2016/0374959 TREATMENT OF EARLY STAGE PARKINSON'S DISEASE WITH A HYDROXYTYROSOL-CONTAINING POLYPHENOL FORMULATION
The invention provides a method for treating a subject suffering from early stage Parkinson's disease with a pharmaceutical formulation containing an olive...
2016/0374958 ANTI-MICROBIAL COMPOSITION COMPRISING CANNABINOIDS
This invention discloses anti-bacterial and anti-fungal compositions in spray form, in cream form, in liquid form, and in powder form. The anti-bacterial and...
2016/0374957 SLOW-RELEASE FORMULATIONS OF 5-HYDROXYTRYPTOPHAN AS AN ADJUNCT TO PRO-SEROTONERGIC THERAPIES
The present invention concerns the treatment of serotonergic dysregulation disordersand/or augmentation of serotonin levels in the brain by add-on treatments...
2016/0374956 MULTILAYER TYPE PATCH
A multilayer-type patch comprising: a support layer; a drug reservoir layer; and an adhesive layer, wherein the drug reservoir layer comprises at least one...
2016/0374955 TRANSDERMAL NICOTINE SALT DELIVERY SYSTEM
A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric...
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