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Patent # Description
2017/0000805 FOOD SUPPLEMENTATION COMPOSITION CONTAINING ONE OR MORE VITAMIN D3 COMPOUNDS AND ONE OR MORE MAGNESIUM SALTS
Use of one or more vitamin D.sub.3 compounds chosen from the group 1-.alpha.-hydroxy vitamin D.sub.3, 25-hydroxy vitamin D.sub.3, 1-.alpha.-, 25-dihydroxy...
2017/0000804 Methods and Compositions for Inhibiting Mitochondrial Trafficking
Methods for reducing, inhibiting or preventing cancer metastasis comprise blocking the movement of mitochondria within a cancer cell. Other methods involve...
2017/0000803 PROGESTERONE FORMULATIONS HAVING A DESIRABLE PK PROFILE
This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular...
2017/0000802 Methods and Compositions for Treating Viral Diseases
The invention provides a method for treating viral infections and coinfections through the use of inhibitory agents that prevent a unique viral structural...
2017/0000801 TRIARYLMETHANE ANALOGS AND THEIR USE IN TREATING CANCERS
Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are triphenyl methane...
2017/0000800 PYRROLO[2,1-F[1,2,4]TRIAZINE COMPOUNDS, PREPARATION METHODS AND APPLICATIONS THEREOF
The present invention relates to a pyrrolo[2,1-f][1,2,4]triazine compound, an isomer thereof or a pharmaceutically acceptable salt, ester or hydrate thereof,...
2017/0000799 ORAL PHARMACEUTICAL COMPOSITION
The present invention relates to solid particles of a poorly soluble drug, pharmaceutical compositions comprising them and processes for their preparation. The...
2017/0000798 TREATMENT OF DEGENERATIONS AND LIGHT-INDUCED DAMAGE TO THE RETINA
The present invention relates to a compound of the following formula (I): ##STR00001## or a pharmaceutically acceptable salt thereof, to be used in the ...
2017/0000797 USE OF SODIUM CHANNEL BLOCKERS FOR THE TREATMENT OF NEUROPATHIC PAIN DEVELOPING AS A CONSEQUENCE OF CHEMOTHERAPY
The present disclosure describes the use of sodium channel blockers such as tetrodotoxin or saxitoxin, its analogues/derivatives as well as their acceptable...
2017/0000796 PTERIDINES AS FGFR INHIBITORS
The invention relates to new pteridine derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said...
2017/0000795 Treatment of Neoplasia
A method of treating cancer in a patient comprising administering to the patient an a systemic chemotherapeutic drug regime in combination with radioactively...
2017/0000794 METHODS FOR MODULATING THE AMOUNT OF RNA TRANSCRIPTS
Described herein are methods for modulating the amount of a gene product and compounds for use in such methods. More particularly, described herein are methods...
2017/0000793 METHODS OF ADMINISTERING TETRAHYDROBIOPTERIN, ASSOCIATED COMPOSITIONS, AND METHODS OF MEASURING
The present invention is directed to treatment methods of administering tetrahydrobiopterin, including in oral dosage forms, in intravenous formulations, and...
2017/0000792 HYDROCHLORIDE SALT OF((1S,2S,4R)-4--2-HYDROXYCYCLOPENTYL) METHYL SULFAMATE
Disclosed is a compound of formula (I): ##STR00001## crystalline forms thereof, and solvates thereof; pharmaceutical compositions comprising a pharmaceutically...
2017/0000791 MALEATE SALTS OF A QUINAZOLINE DERIVATIVE USEFUL AS AN ANTIANGIOGENIC AGENT
The present invention relates to AZD2171 maleate salt, to particular crystalline forms of AZD2171 maleate salt, to processes for their preparation, to...
2017/0000790 SMALL MOLECULE TRAIL GENE INDUCTION BY NORMAL AND TUMOR CELLS AS AN ANTICANCER THERAPY
Methods and compositions relating to TIC10 are described according to aspects of the present invention. The compositions and methods have utility in treating...
2017/0000789 Methods of Treating Tumoral Diseases, or Bacterial or Viral Infections
Novel compounds and their synthesis are described. Methods for using these compounds in the prevention or treatment of cancer, a bacterial infection or a viral...
2017/0000788 Cap/endo dual inhibitors and their use in the treatment, amelioration or prevention of a viral disease
The present invention relates to a compound having the general formula (V), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph,...
2017/0000787 AURORA KINASE INHIBITORS AND METHODS OF MAKING AND USING THEREOF
Described herein are inhibitors of Aurora kinase and their use in the treatment of cancer. Methods of screening for selective inhibitors of Aurora kinases are...
2017/0000786 Piperazine-Substituted Benzothiophenes For Treatment of Mental Disorders
The present invention provides a heterocyclic compound represented by the general formula (1): The compound of the present invention has a wide treatment...
2017/0000785 INHIBITORS OF THE FKBP51 PROTEIN FROM A HIGH-THROUGHPUT DRUG SCREEN AND METHODS OF USE
The subject invention concerns materials and methods for treating depression, stress disorders, such as PTSD, anxiety disorders, and/or a neurodegenerative...
2017/0000784 Autophagy Inhibitors
The present invention relates to compounds of Formula III, Formula 111(a), Formula V, Formula V(a), Formula A, Formula A 1, Formula A2, Formula A 3, or a...
2017/0000783 Multiparticulate Modified Release Composition
The invention relates to a multiparticulate modified release composition that, upon administration to a patient, delivers at least one active ingredient in a...
2017/0000782 METHODS FOR TREATING PRURITUS
The present invention relates to methods for treating uremic pruritus with anti-pruritic compositions.
2017/0000781 QUINOLINES AS FGFR KINASE MODULATORS
The invention relates to new quinoline derivative compounds of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the...
2017/0000780 COMPOSITIONS, METHODS AND KITS FOR REDUCING LIPID LEVELS
Compositions, methods, and kits useful for treating hyperlipidemic conditions are provided herein. Such compositions can contain synergizing amounts of...
2017/0000779 Modulation of Stem Cell and Progenitor Cell Differentiation, Assays, And Uses Thereof
The present invention relates to methods of modulating mammalian stem cell and progenitor cell differentiation. The methods of the invention can be employed to...
2017/0000778 DOSAGE REGIMEN FOR AN ALPHA-ISOFORM SELECTIVE PHOSPHATIDYLINOSITOL 3-KINASE INHIBITOR
The present invention relates to methods of treating or preventing a proliferative disease in a patient in need thereof by orally administering a...
2017/0000777 COMPOSITIONS, METHODS, AND KITS FOR REGULATING ENERGY METABOLISM
The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that...
2017/0000776 Method for Treatment of Radiologically-Dense Breasts
Nitrone, nitroso, and nitroxide spintraps and spin labels and their reduction products are claimed for the treatment of dense breasts.
2017/0000775 PHARMACEUTICAL COMPOSITIONS COMPRISING ANTIBACTERIAL AGENTS
Pharmaceutical compositions comprising sulbactam or a pharmaceutically acceptable derivative thereof, and compound of Formula (I) or a stereoisomer or a...
2017/0000774 MYELOID DIFFERENTIATION INDUCING AGENTS
Myeloid differentiating agents can be used in the treatment of myeloid proliferative disorders.
2017/0000773 SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLES, METHODS FOR USE THEREOF
The present invention relates to a method of antagonizing a 5-HT.sub.6 serotonin receptor, comprising administering to the cell a compound of formula 1.2, or a...
2017/0000772 SMALL MOLECULE MODULATORS OF PRB INACTIVATION
The present invention provides a small molecule treatment of diseases/conditions caused by a virus carrying a viral oncoprotein. In one embodiment, the virus...
2017/0000771 Thromboxane Receptor Antagonists in AERD/Asthma
The present invention is directed to methods of treating AERD (aspirin exacerbated respiratory disease) and/or asthma via the administration of a thromboxane...
2017/0000770 CARBOXAMIDE DERIVATIVES
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; ##STR00001## a method for manufacturing the compounds of...
2017/0000769 NADPH Production by the 10-Formyl-THF Pathway, and Its Use in the Diagnosis and Treatment of Disease
A 10-formyl-THF pathway for producing NADPH is useful in the diagnosis and treatment of cancer and metabolic disease, in the development of new antineoplastic...
2017/0000768 COMPOSITIONS AND METHODS RELATING TO HEAT SHOCK TRANSCRIPTION FACTOR ACTIVATING COMPOUNDS AND TARGETS THEREOF
The present invention relates to HSF activating compounds, methods for their discovery, and their research and therapeutic uses, as well as pharmaceutically...
2017/0000767 THERAPEUTIC OR PROPHYLACTIC AGENT FOR MULTIPLE SCLEROSIS
A therapeutic or prophylactic agent for multiple sclerosis includes as an effective component a cyclohexane derivative represented by Formula (I): ##STR00001## ...
2017/0000766 Methods and Compositions Involving (S)-Bucindolol
Disclosed is bucindolol substantially free of its R-stereoisomer. Also disclosed are pharmaceutical compositions that include bucindolol substantially free of...
2017/0000765 TRIPTAN POWDERS FOR PULMONARY DELIVERY
The invention provides stable, spray-dried, particle formulations containing a triptan, preferably sumatriptan, or a pharmaceutically acceptable salt thereof,...
2017/0000764 PHARMACEUTICAL COMPOSITION WITH IMPROVED BIOAVAILABILITY
The invention relates to solid dispersions of poorly water soluble compounds, in particular Compound A as disclosed herein, formed by solvent co-precipitation...
2017/0000763 ORALLY ADMINISTRABLE COMPOSITIONS COMPRISING AVOCADO/SOYBEAN UNSAPONIFIABLES AND LIPOIC ACID AND METHODS OF...
An orally administrable composition for treating or reducing damage to connective tissue or for treating or reducing inflammatory symptoms associated with...
2017/0000762 ANTI-MICROBIAL COMPOSITION
This invention pertains to an anti-microbial, in particular anti-bacterial and/or anti-fungal composition comprising cinnamaldehyde, ...
2017/0000761 PROTECTING TISSUE AND MITIGATING INJURY FROM CHEMICAL EXPOSURE
Materials and methods for reducing, preventing, or mitigating the effects of exposure to toxic chemical agents.
2017/0000760 METHODS FOR INHIBITING CANCER CELLS
The present invention provides methods for treating cancer, by administering a therapeutically effective amount of a compound of formula (I), or a...
2017/0000759 Pharmaceutical Composition Including 5--2,2-Dimethyl-4-(3-Fluorophenyl)-3(2H)-Furanone And Capsule Formulation ...
The present invention relates to a pharmaceutical composition including (i) the compound of Formula 1 described in the specification or a pharmaceutically...
2017/0000758 GEL COMPOSITION FOR TREATMENT OF COMMON ACNE COMPRISING A COMBINATION OF BENZOYL PEROXIDE AND ADAPALENE AND/OR...
Dermatological/cosmetic compositions suited for preventing or treating cell differentiation and/or proliferation and/or keratinization disorders, including...
2017/0000757 THERAPEUTIC APPLICATION OF (BOC)2-CREATINE
A creatine derivative, (Boc)2-creatine, is used as a medicament, in particular in a therapeutic antitumor treatment. I (Boc)2-creatine.
2017/0000756 METHODS FOR TREATING OR PREVENTING FATIGUE
The present invention relates to the use of compounds of the invention for treatment and/or prevention of fatigue, including fatigue associated with diseases...
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