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Patent # Description
2017/0014442 METHOD FOR PREVENTION OF COLECTOMY
A method of treating chronic active ulcerative colitis in a subject that is refractory or responds insufficiently or is intolerant to anti-inflammatory...
2017/0014441 INDUCTION OF THYROID IODIDE-HANDLING GENE EXPRESSION IN HUMAN CANCERS
Dual suppression of the MAP kinase and PI3K/Akt pathways showed synergistic or greatly enhanced anti-melanoma cell effects, compared to suppression of a single...
2017/0014440 COMPOSITIONS COMPRISING DECITABINE AND TETRAHYDROURIDINE AND USES THEREOF
Embodiments of compositions and methods for the treatment of blood disorders and malignancies in a subject are described herein. In one embodiment, a...
2017/0014439 FLAVONOID COMPOSITIONS AND USES THEREOF
This invention relates to a flavonoid composition that includes eriocitrin. The flavonoid may be included in a complex with other bioflavonoids. The...
2017/0014438 ANTI- ESOPHAGEAL CANCER COMPOUND AND METHOD OF USE THEREOF
The present invention relates to the bioactive components with the anti-proliferative property. In particular, the invention relates to one flavonol compound...
2017/0014437 SYNTHETIC DISUGAR HYDROCARBONS AS NATURAL ANALOGS TO CONTROL MICROBIAL BEHAVIORS
Synthetic disaccharide hydrocarbons (DSHs) that reactive bacterials swarming motility and inhibit bacterial adhesion and biofilm formation. A library of DSHs...
2017/0014436 Oral formulations Mimetic of Roux-en-Y gastric bypass actions on the ileal brake; Compositions, Methods of...
The invention provides pharmaceutical compositions, methods for the treatment of, and related diagnostics and computer-implementable systems that relate to,...
2017/0014435 USE OF THIOPYRIMIDINECARBOXAMIDE FOR TREATING CANCER
There is disclosed is a method of treating cancer using compound having formula SX-682 ##STR00001## alone or in combination with an antineoplastic agent,...
2017/0014434 Small Molecule HSP70 Inhibitors
In an effort to discover therapies for treating HSP70 related diseases, a previously unidentified hydrophobic pocket was found in the C-terminal domain of DnaK...
2017/0014433 COMBINATION THERAPY FOR SKIN DISORDERS
The present invention provides a novel therapeutic combination comprising one or more anti-androgen agents and one or more antibiotic/anti-inflammatory agents...
2017/0014432 COMPOSITIONS AND METHODS FOR REDUCING CHRONIC LOW-LEVEL INFLAMMATION
The invention relates to compositions and methods for reducing chronic low-level inflammation associated with chronic conditions. Specifically, the invention...
2017/0014431 ROCURONIUM BROMIDE INJECTION SOLUTION-FILLED PREFILLED SYRINGE
A rocuronium bromide injection solution-prefilled syringe of the present invention includes a syringe comprising an outer cylinder made of synthetic resin, a...
2017/0014430 Cycloartenol-Containing Composition
Provided is a cycloartenol-containing composition which can be used as a material for food and beverage, cosmetics, or the like, and has high biological...
2017/0014429 USES OF OXYGENATED CHOLESTEROL SULFATES (OCS)
Methods of preventing and/or treating ischemia, organ dysfunction and/or organ failure, including multiple organ dysfunction syndrome (MODS), and necrosis and...
2017/0014428 INJECTABLE PHARMACEUTICAL COMPOSITIONS COMPRISING A CYCLODEXTRIN A HYDROPHOBIC DRUG, A CO-SOLVENT, AND A...
Injectable pharmaceutical compositions, methods of use and formulation are disclosed. The compositions comprise: one or more water soluble complexes, each...
2017/0014427 Composition and Method for Curing Migraine Headaches
The invention is directed to methods and compositions for curing migraine headaches. In particular, compositions are described involving the combination of...
2017/0014426 ULIPRISTAL ACETATE FOR PREVENTION AND TREATMENT OF BREAST TUMORS
The invention relates to the use of ulipristal acetate, or any of its metabolites, in preventing or treating a breast tumor in a patient, preferably a patient...
2017/0014425 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATINGHEARING LOSS, COMPRISING CARBENOXOLONE OR ITS...
The present invention is related to a pharmaceutical composition and health food for preventing or treating hearing loss, wherein the pharmaceutical...
2017/0014424 ADMINISTRATION OF ILOPROST AS AEROSOL BOLUS
The present invention relates to novel methods, compositions and kits useful for the treatment of pulmonary diseases such as pulmonary arterial hypertension....
2017/0014423 Benzazepine Dicarboxamide Compounds
This invention relates to novel benzazepine dicarboxamide compounds of the formula ##STR00001## wherein R.sup.1 to R.sup.4 are as defined in the ...
2017/0014422 PHARMACEUTICAL COMPOSITION COMPRISING IVABRADINE HYDROCHLORIDE POLYMORPH IV
The present invention relates to stable pharmaceutical compositions comprising ivabradine hydrochloride polymorph IV, characterized in that the composition is...
2017/0014421 PIPERAZINE PHENOTHIAZINE DERIVATIVES FOR TREATING SPASTICITY
The present invention relates to piperazine phenothiazine derivatives useful as therapeutic agents for treating spasticity, particularly following an ischemia...
2017/0014420 USE OF NK-1 RECEPTOR ANTAGONISTS FOR TREATING HYPOMAGNESEMIA, NEUROGENIC INFLAMMATION, AND CARDIAC DYSFUNCTION...
The present disclosure provides methods for alleviating or preventing the negative physiological side effects associated with the administration of EGFR...
2017/0014419 MEDICAMENT FOR SUPPRESSING MALIGNANT TUMOR METASTASIS
Provided are a novel medicament for suppressing or preventing the metastasis of a malignant tumor such as carcinoma, a novel treatment or prevention method for...
2017/0014418 BICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS
The present invention relates to bicyclic heterocycles which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are useful in the treatment...
2017/0014417 PHARMACEUTICAL ADMINISTRATION SYSTEM FOR THE TRANSDERMAL APPLICATION OF VARDENAFIL
A pharmaceutical administration system for the transdermal application of at least one active agent includes vardenafil and/or a pharmaceutically acceptable...
2017/0014416 Compositions And Methods For Treatment Of Psychiatric Disorders
Compositions and methods for the treatment of a unipolar depression containing betaine, and folate. Formulations for oral administration optionally also...
2017/0014415 THIENO- AND PYRROLOPYRIMIDINE ANALOGUES AS ANTICANCER AGENTS AND METHODS OF USE THEREOF
The present invention provides for the design and synthesis of halogenated thieno- and pyrrolopyrimidine compounds that exhibit cancer proliferation inhibitory...
2017/0014414 PHARMACEUTICAL COMPOSITION
A pharmaceutical composition including trametinib or a pharmaceutically acceptable salt thereof as active ingredient and a carrier is described herein. Also...
2017/0014413 NOVEL KIF5B-RET FUSION MOLECULES AND USES THEREOF
Novel RET fusion molecules and uses are disclosed. In one embodiment, a KIF5B-RET fusion includes an in-frame fusion of an exon of KIF5B (e.g., one or more...
2017/0014412 OUTPATIENT MODIFIED RAPID DETOXIFICATION FOR ADDICTION TO ALCOHOL AND DRUGS
A program for outpatient modified rapid detoxification for addiction to alcohol and drugs is disclosed. Patients are seen by trained medical professionals who...
2017/0014411 FLUOROCYCLOPENTENYLCYTOSINE METHODS OF USE
The disclosed subject matter provides methods using and kits comprising a compound of formula (I) ##STR00001## or a hydrate, a solvate, or a pharmaceutically...
2017/0014410 TREATMENT OF PROLIFERATIVE DISORDERS WITH A CHEMILUMINESCENT AGENT
Methods employing chemiluminescent agents as therapeutically active agents in the treatment of proliferative disorders are disclosed. The chemiluminescent...
2017/0014409 TREATING INFLAMMATION USING SERELAXIN
The present disclosure relates to methods of treating inflammation in a subject. Particularly, the disclosure provides methods for treating inflammation by...
2017/0014408 HEPATITIS B ANTIVIRAL AGENTS
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR00001## which inhibit the...
2017/0014407 PYRIDAZINE DERIVATIVES FOR USE IN THE PREVENTON OR TREATMENT OF AN ATAXIC DISORDER
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, ##STR00001## wherein R.sup.1 and R.sup.2 are as defined in...
2017/0014406 ABUSE-RESISTANT CONTROLLED-RELEASE OPIOID DOSAGE FORM
Abuse-resistant, controlled release opioid tablets are a combination containing an opioid antagonist such as naloxone at a level above that needed to suppress...
2017/0014405 ABUSE-RESISTANT CONTROLLED-RELEASE OPIOID DOSAGE FORM
Abuse-resistant, controlled release opioid tablets are a combination containing an opioid antagonist such as naloxone at a level above that needed to suppress...
2017/0014404 SUSTAINED RELEASE FORMULATION OF NALTREXONE
A sustained-release oral dosage form of naltrexone or a pharmaceutically acceptable salt thereof is provided. The oral dosage form may be administered with...
2017/0014403 Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity
The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may...
2017/0014401 NUCLEAR RECEPTOR BINDING AGENTS
The present application relates to methods of treating, preventing, delaying the onset of, reducing the incidence of, or reducing the severity of fibrosis,...
2017/0014400 METHOD OF TREATING OR PREVENTING HYPERLIPIDEMIA WITH CAFFEAMIDE DERIVATIVES
The present invention provides a method of treating or preventing hyperlipidemia in a subject in need thereof. Such method includes, specifically,...
2017/0014399 ANDROGEN RECEPTOR MODULATOR FOR THE TREATMENT OF PROSTATE CANCER AND ANDROGEN RECEPTOR-ASSOCIATED DISEASES
Described herein, inter alia, are compounds useful for the prevention or treatment of hyperproliferative diseases or disorders.
2017/0014398 TOPICAL RETINOID COMPOSITIONS
The present application relates to topical compositions. In particular, the present application relates to a topical composition comprising retinoid as active...
2017/0014397 IRON CHELATORS FOR TREATING AND PREVENTING CELL DEATH AND ORGAN DAMAGE FOLLOWING AN ISCHEMIC EVENT
Disclosed are methods and compositions for treating or preventing a disease or disorder responsive to a decrease in baseline mitochondrial iron in a subject in...
2017/0014396 PHARMACEUTICAL COMPOSITIONS OF THERAPEUTICALLY ACTIVE COMPOUNDS
Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need...
2017/0014395 ENDOPARASITE CONTROL AGENT AND METHOD FOR USING THE SAME
An object of the present invention is to provide a novel endoparasite control agent as a parasiticide, an antiprotozoal or the like. Provided is an...
2017/0014394 THIENOPYRIDINE DERIVATIVE FOR THE TREATMENT OF HEPATITIS C INFECTIONS
The present invention relates to methods of treatment of hepatitis C using prasugrel. The methods of the present invention can be used in patients with...
2017/0014393 METHODS OF TREATING DEVELOPMENTAL DISORDERS WITH GABOXADOL
Methods of treating developmental disorders such as Angelman syndrome, Fragile X syndrome, Fragile X-associated tremor/ataxia syndrome (FXTAS), Autistic...
2017/0014392 METHODS OF TREATING DEVELOPMENTAL DISORDERS USING GABOXADOL
Methods of treating a developmental disorder such as Dravet syndrome by administering a pharmaceutical composition of gaboxadol or a pharmaceutically...
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