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Patent # Description
2017/0014391 SGK1 INHIBITORS FOR TREATMENT OF PROSTATE CANCER
The present invention encompasses the recognition that reproducible and detectable changes in the level and or activity of SGK1 are associated with incidence...
2017/0014390 TREATMENT OF PROGRESSIVE NEURODEGENERATIVE DISEASE WITH IBUDILAST
Compositions and methods for treating progressive neurodegenerative diseases, and their associated symptoms by administration of ibudilast ...
2017/0014389 INHALABLE AZTREONAM LYSINATE FORMULATION FOR TREATMENT AND PREVENTION OF PULMONARY BACTERIAL INFECTIONS
A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by...
2017/0014388 CARBOXAMIDE DERIVATIVES
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; ##STR00001## a method for manufacturing the compounds of...
2017/0014387 Methods of Reducing Mammographic Breast Density and/or Breast Cancer Risk
The present disclosure is directed to generally methods for treating mammographic breast density and/or breast stiffness in a patient in need thereof, such as...
2017/0014386 Treatment of Multidrug-Resistant Nephrotic Syndrome (MDR-NS) in Children
The present disclosure provides compositions and methods for treating multidrug-resistant nephrotic syndrome (MDR-NS) in pediatric subjects comprising...
2017/0014385 DIARYL AND ARYLHETEROARYL UREA DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE...
The present invention relates to certain pyrazole derivatives of Formula (I) and pharmaceutical compositions thereof that modulate the activity of the...
2017/0014384 METHOD FOR INHIBITING TUMOR METASTASIS
A leukotriene C4 and D4 antagonist is used to inhibit tumor metastasis by acting to inhibit tumor cell adhesion to endothelial cells, therby preventing tumor...
2017/0014383 SOLID DISPERSION OF INDIRUBIN
The invention described herein provides a solid dispersion of Indirubin, a pharmaceutical composition comprising the solid dispersion of Indirubin, a process...
2017/0014382 SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES
Disclosed herein are self-emulsifying compositions and formulations of Diindolylmethane ("DIM") and certain derivatives of DIM, their uses and methods of...
2017/0014381 NEW SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS
3-aza-bicyclo[3.1.0]hexane-6-carboxylic acid amide derivatives which are agonists of somatostatin receptor subtype 4 (SSTR4), useful for preventing or treating...
2017/0014380 Vildagliptin Formulation Process Under Inert Gas Atmosphere
The present invention relates to a process for preparing a pharmaceutical composition of vildagliptin under oxygen free inert gas atmosphere. The present...
2017/0014379 Pharmaceutical Formulations of Vildagliptin
The present invention relates to a pharmaceutical formulation comprising therapeutically effective amount of vildagliptin or pharmaceutically acceptable salt...
2017/0014378 COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS
The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof: ##STR00001##
2017/0014377 ANTHOCYANIDIN COMPLEX
The invention relates to a complex of an anthocyanidin and a methylated .beta.-cyclodextrin which can be formulated as an aqueous solution and as a solid, and...
2017/0014376 SYSTEMS, METHODS, AND FORMULATIONS FOR TREATING CANCER
A method and compositions for treating cancer is described using at least two epigenetic modifiers. In various embodiments, hyperbaric oxygen therapy and...
2017/0014375 PHARMACEUTICAL COMPOSITION COMPRISING EFFECTIVE DOSE OF POMIFERIN FOR TREATING CANCERS
The present invention provides a compound of formula (I) as a SERCA inhibitor for treating cancers, a pharmaceutical composition comprising said compound, and...
2017/0014374 COMPOSITION FOR TREATMENT OF DYSLIPIDEMIA AND INFLAMMATION
The present invention provides compositions that are substantially niacin free for treating dyslipidemia and/or inflammation in a subject. Compositions of the...
2017/0014373 METHODS OF TREATING CANCER
The present invention provides methods and compositions for treating non-small-cell lung cancer (NSCLC) by administering a) a composition comprising...
2017/0014372 Drug Combination for Treatment of Proliferative Diseases
Angiogenesis inhibitory drug combination obtained according to a specific algorithm, preferably a FSC, in which an initial combination of drugs is iteratively...
2017/0014371 SARMS AND METHOD OF USE THEREOF
This invention is directed to substituted acylanilide compounds and uses thereof in treating muscular dystrophies such as Duchenne muscular dystrophy and...
2017/0014370 SARMS AND METHOD OF USE THEREOF
This invention is directed to substituted acylanilide compounds and uses thereof in improving or preserving lung function and cardiac function in a subject...
2017/0014369 COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF
There are provided compositions comprising ##STR00001## Such compositions can also further comprise various components such as lipids (for example fatty acids,...
2017/0014368 RETINAL DERIVATIVES AND METHODS FOR THE USE THEREOF FOR THE TREATMENT OF VISUAL DISORDERS
Compositions of and methods for using synthetic retinal derivatives as retinoid replacements and opsin agonists are provided.
2017/0014367 CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS COMPRISING A FUMARIC ACID ESTER
The present invention relates to controlled release pharmaceutical compositions comprising fumaric acid ester(s) as active substance(s). The compositions are...
2017/0014366 METHODS OF TREATING MIXED DYSLIPIDEMIA
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
2017/0014365 Compositions Containing Very Long Chain Saturated Fatty Acids and Methods of Use
A fatty acid composition comprising at least one purified very long chain saturated fatty acid (VLC-SFA) having a chain length in a range of from about 28...
2017/0014364 ENDOPROSTHESIS HAVING AND ACTIVE SUSBTANCE COATING
The present invention relates to an endoprosthesis with a drug coating comprising or consisting of at least one antibiotic agent and at least one further...
2017/0014363 Treatment of intrahepatic cholestatic diseases
Treatment of intrahepatic cholestatic diseases by therapy with MBX-8025 or an MBX-8025 salt.
2017/0014362 ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE
The present invention provides novel compounds with hypocholesteremic activity from crude Embilica officinialis (EO) extracts and methods of use. The invention...
2017/0014361 MITOCHONDRIAL DELIVERY OF 3-BROMOPYRUVATE
A mitochondria targeted gold nanoparticle (T-3-BP-AuNP) decorated with 3-bromopyruvate (3-BP) and delocalized lipophilic triphenylphosphonium (TPP) cations to...
2017/0014360 METHODS OF TREATING CANCER USING RAD51 SMALL MOLECULE STIMULATORS
Methods of killing or inhibiting the growth cancer cells and tumors and of treating cancer by administering compounds that stimulate the activity of RAD51....
2017/0014359 HIGH CONCENTRATION LOCAL ANESTHETIC FORMULATIONS
A transdermal topical anesthetic formulation, which can be used to ameliorate or inhibit pain, has been developed. In the preferred embodiment, the topical...
2017/0014358 COMPOSITION AND METHOD FOR ENHANCING WOUND HEALING
The invention relates to a composition for enhancing wound healing and/or for reducing pain and inflammation, comprising a first active ingredient and a second...
2017/0014357 COMPOSITIONS AND METHODS FOR INCREASING THE METABOLIC LIFETIME OF DEXTROMETHORPHAN AND RELATED PHARMACODYNAMIC...
This disclosure relates to methods administering various compounds in conjunction with dextromethorphan to a human being. Dosage forms, drug delivery systems,...
2017/0014356 METHODS OF ENHANCING IMMUNITY IN A COMPANION ANIMAL
Disclosed herein are methods for enhancing the immune response of a companion animal, comprising administering to a companion animal a composition comprising...
2017/0014355 CANNABINOID RECEPTOR TREATMENTS
The present invention includes methods and compositions for treating a transplant recipient by administration of a CB.sub.2 receptor agonist either alone or in...
2017/0014354 ZEAXANTHIN FOR TUMOR TREATMENT
A composition comprising a pharmaceutically effective amount of zeaxanthin or its derivative for use in treating a malignant tumor and a method of using a...
2017/0014353 Pramipexole-Containing Transdermal Patch for Treatment of Neurodegenerative Disease
The purpose of the present invention is to provide a nonaqueous tape that is stable and has high percutaneous absorption performance, and that contains...
2017/0014352 WATER-DISPERSIBLE AMORPHOUS PARTICLES AND METHOD FOR PREPARING SAME
The present invention pertains to spherical water-dispersible amorphous particles having a particle diameter of 10-990 nm and a PDI of 0.01-0.5, wherein the...
2017/0014351 ENGINEERED FLUORINATED BIOMATERIALS
Provided are protein polymers providing the dual functionality of delivery and imaging. The protein polymers comprise a coiled-coil domain of the cartilage...
2017/0014350 ORAL VIRUS VACCINE
The present disclosure relates to a polymer-coated virus particle for an oral virus vaccine, a method of preparing the same, and a composition comprising the...
2017/0014349 TREATING SOFT TISSUE VIA CONTROLLED DRUG RELEASE
Methods for inhibiting tissue ossification or calcification in a subject, comprising administering a therapeutically effective amount of BMP I inhibitor-loaded...
2017/0014348 Formulations of Nonopioid and Confined Opioid Analgesics
The preferred exemplary embodiments in the present application provide formulations and methods for the delivery of drugs, particularly drugs of abuse, having...
2017/0014347 DRY COATED TABLET
Provided is a dry coated tablet showing high stability of the active ingredient (proton pump inhibitor, acetylsalicylic acid), which stably and rapidly...
2017/0014346 Spray Drying Process for Production of Powders with Enhanced Properties
An improved spray drying method for production of amorphous solid dispersions with enhanced bulk density and material attributes comprising the introduction of...
2017/0014345 PHARMACEUTICAL COMPOSITION
This invention relates to pharmaceutical formulations comprising particles with a substantially non-hygroscopic inner crystalline core and an outer coating...
2017/0014344 DRUG CARRIER AND MANUFACTURING METHOD THEREOF
A drug carrier and a manufacturing method thereof are provided. The drug carrier includes a hydrophilic group, a hydrophobic group and an organic dye. The...
2017/0014343 STABLE PHARMACEUTICAL COMPOSITION OF CLOPIDOGREL FREE BASE FOR ORAL AND PARENTERAL DELIVERY
The present disclosure provides ready-to-use, oil/water emulsion compositions with mean droplet size (intensity-average, nm) of 100-500 nm, where the oil phase...
2017/0014342 HIGH DELIVERY RATES FOR LIPID BASED DRUG FORMULATIONS, AND METHODS OF TREATMENT THEREOF
Provided is a method of preparing lipid based drug formulations with low lipid/drug ratios using coacervation techniques. Also provided are methods of...
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