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Method for increasing plant yields
The present invention provides methods for obtaining plants that exhibit useful traits by expression of a DNA methyltransferase fusion protein in progenitor...
AGENTS FOR ENHANCEMENT OF PRODUCTION OF BIOFUEL PRECURSORS IN MICROALGAE
We identified 17 transcription factor genes that regulate lipid production and activity in an organism. We subsequently detailed characterization of one of...
METHOD FOR THE PRODUCTION OF MULTIPLE-UNSATURATED FATTY ACIDS IN
The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids...
TRANSGENIC PLANTS EXPRESSING A pH-SENSITIVE NITRATE TRANSPORTER
The invention relates to transgenic plants with improved growth and nitrogen use efficiency expressing nitrate transporter gene, methods of making such plants...
NOVEL USE OF A DENSE AND ERECT PANICLE 1 GENE IN IMPROVING NITROGEN
The present invention provides methods of increasing nitrogen utilization efficiency (NUE) in a transgenic plant comprising the introduction of a nucleic acid...
Methods and Compositions for Weed Control
Novel compositions for use to enhance weed control. Specifically, the present invention provides for methods and compositions that modulate protoporphyrinogen...
METHOD FOR HIGH EFFICIENCY PROTEIN DELIVERY INTO PLASTIDS
The present invention provides a recombinant DNA molecule encoding a fusion protein, comprising a first DNA sequence encoding a high-efficiency transit peptide...
METHODS AND COMPOSITIONS FOR IDENTIFYING AND ENRICHING FOR CELLS
COMPRISING SITE SPECIFIC GENOMIC MODIFICATIONS
The present invention relates to methods and compositions for modifying a target site in the genome of a plant cell. Such modifications include integration of...
DNA MOLECULE USED FOR RECOMBINANT PICHIA PLASMID AND RECOMBINANT PICHIA
STRAIN EXPRESSING PPRI PROTEIN OF...
A DNA molecule comprising the sequence set forth in SEQ ID NO: 1, a recombinant Pichia plasmid into which the DNA molecule is inserted, and a recombinant...
DESIGN OF mRNA SEQUENCES TO CONTROL CO-TRANSLATIONAL FOLDING OF PROTEINS
This invention relates to optimized heterologous production of properly folded and functional proteins. The present invention provides systems and methods...
VITAMIN PROTOTROPHY AS A SELECTABLE MARKER
One or more genes in a biosynthesis pathway for a vitamin or other essential nutrient which is needed for the survival of a microorganism can be used as an...
GENERATION OF ACYL AMINO ACIDS
Engineered polypeptides useful in synthesizing acyl amino acids are provided. Also provided are methods of making acyl amino acids using engineered...
PHARMACEUTICAL COMPOSITION AND METHOD FOR REDUCING SCAR FORMATION
Disclosed herein is a pharmaceutical composition for reducing scar formation in a subject in need thereof. The pharmaceutical composition includes a mixture of...
DDX5 AND ASSOCIATED NON-CODING RNAs AND MODULATION OF TH17 EFFECTOR
Methods for screening to identify agents capable of modulating DDX5 polypeptide activity are encompassed herein as are methods for using such agents to treat...
COMPOSITION FOR PROMOTING CHONDROCYTE DIFFERENTIATION OR TREATING
CARTILAGE DISEASES, CONTAINING KLF10...
The present invention relates to a Krueppel-like factor 10 (KLF10) gene expression inhibitor promoting cartilage differentiation, and more specifically, to: a...
Method of Treating Cancer by Inhibition of DNA Repair Proteins
Methods of treating cancer using antisense oligonucleotides directed against DNA double-strand break repair proteins such as BRCA2 or RAD51 are provided. The...
ASYMMETRIC INTERFERING RNA COMPOSITIONS THAT SILENCE K-RAS AND METHODS OF
The invention provides novel compositions for use in silencing K-Ras gene expression. More particularly, the invention provides novel asymmetrical interfering...
COMPOSITIONS AND AGENTS AGAINST HEPATITIS B VIRUS AND USES THEREOF
This invention encompasses compounds and compositions useful in methods for medical therapy, in general, for inhibiting Hepatitis B virus in a subject. The...
COMPOSITIONS AND METHODS FOR TREATMENT OF OVARIAN CANCER
The disclosure provides compositions and methods for treating an ovarian cancer in a subject. More specifically, the disclosure provides microRNA (miRNA)...
LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY
The instant invention provides for novel cationic lipids that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form...
COMPOSITIONS AND METHODS FOR TREATING CACHEXIA
The present invention relates, in various embodiments, to methods of treating cachexia (e.g., cancer cachexia) in a patient. The methods comprise administering...
COMPOSITIONS AND METHODS FOR MODULATION OF SMN2 SPLICING IN A SUBJECT
Disclosed herein are compounds, compositions and methods for modulating splicing of SMN2 mRNA in a subject. Also provided are uses of disclosed compounds and...
METHODS FOR IN VIVO GENOME EDITING
Methods of transfecting cells in vivo, by administering an injectable pharmaceutical composition including a genome editing composition and a pharmaceutically...
NUCLEIC ACID EXTRACTING DEVICE
A nucleic acid extracting device includes an upper module, a lower module, and a material for capturing nucleic acid. The lower module has a sample reservoir...
NUCLEIC ACID EXTRACTION METHOD
A nucleic acid extraction method includes the following steps. Firstly, a mixture of a sample and a lysis buffer is provided. The pH of the lysis buffer is...
HYBRID POLYMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF SYNTHESIZING
Novel hybrid polymers are disclosed that have a structure represented by the following formula I: ##STR00001## wherein Abiotic oligomer, Polypeptide, X, Y, and...
HYBRID POLYKETIDE SYNTHASES
The present invention provides for a polyketide synthase (PKS) capable of synthesizing an even-chain or odd-chain diacid or lactam or diamine. The present...
THERMOSTABLE BLUNT-END LIGASE AND METHODS OF USE
Fusion proteins having thermostable blunt-end ligase activity are provided. Blunt-end ligases are useful for DNA amplification, sequencing, production of...
ENHANCING MICROBIAL METABOLISM OF C5 ORGANIC CARBON
Provided herein are recombinant microorganisms having two or more copies of a nucleic acid sequence encoding xylose isomerase, wherein the nucleic acid...
MODIFIED CASPASE POLYPEPTIDES AND USES THEREOF
The technology relates in part to compositions comprising modified Caspase-9 polypeptides, compositions comprising nucleic acids coding for modified Caspase-9...
Methods For Producing Multiple Recombinant Polypeptides In A Filamentous
Fungal Host Cell
The present invention relates to methods for constructing a filamentous fungal strain for production of multiple recombinant polypeptides having biological...
Polypeptides Having Alpha-Glucuronidase Activity And Polynucleotides
The present invention relates to isolated polypeptides having alpha-glucuronidase activity, catalytic domains and polynucleotides encoding the polypeptides,...
The present invention relates to isolated polypeptides having alpha-L-arabinofuranosidase activity and isolated nucleic acid sequences encoding the...
METHODS AND PRODUCTS FOR EXPRESSING PROTEINS IN CELLS
The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells...
POLYPEPTIDES WITH LIPASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME
Provided are isolated polypeptides with lipase activity and polynucleotides encoding the polypeptides. Also provided are nucleic acid constructs, vectors, and...
Modified Bacillus Cereus Phospholipase C Protein And Method Of Processing
A modified Bacillus cereus phospholipase C enzyme is provided, as well as a method of using the modified phospholipase C enzyme in a method of treating...
PHI29 DNA POLYMERASE MUTANTS HAVING INCREASED THERMOSTABILITY AND
Mutants of bacteriophage phi29 DNA polymerase with increased protein stability and increased half-life, compared to wild type DNA polymerase. The disclosed...
TETRACYCLINE RESISTANT EUKARYOTIC CELLS EXPRESSING AN NADP-REQUIRING
TETX, a tetracycline degrading enzyme, is provided as a selection marker for eukaryotic cells. Polynucleotide molecules containing tetx and DNA constructs...
Novel 7Beta-Hydroxysteroid Dehydrogenase Mutants and Process for the
Preparation of Ursodeoxycholic Acid
The invention relates to novel 7.beta.-hydroxysteroid dehydrogenase mutants, to the sequences which encode these enzyme mutants, to processes for the...
HIGH-SAFETY PROCESS FOR THE PREPARATION OF PURIFIED STEM CELL FRACTIONS
A highly safe procedure for the preparation of purified stem cell fractions of lipid origin is herein described, in which the use of a specially designed...
GENETICALLY MODIFIED MESENCHYMAL STEM CELLS THAT EXPRESS AN EXOGENOUS
This invention provides a method for treating a subject afflicted with a tumor using genetically modified mesenchymal stem cells, wherein each genetically...
CELL MODULATION NANOCOMPOSITION, AND METHODS OF USE
A nanocomposition for modulating cell behaviors and methods of uses thereof. The nanocomposition comprises a nanostructure comprising at least one nanoparticle...
The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and...
COLLAGEN HYDROGEL KIT AND METHODS OF MAKING A COLLAGEN HYDROGEL
Provided is a kit and method for preparing a collagen hydrogel media matrix. The kit includes a collagen, a cell growth medium, a serum supplement, an organic...
High Pressure Bioreactor
The present invention relates generally to an integrated system, apparatus and method that allows for the continuous culturing of microorganisms under high...
ELECTROCHEMICAL MEASUREMENT DEVICE
An electrochemical measurement device includes: a base; a specimen placement portion disposed on the base, for placing a biological specimen; a first electrode...
System for Separation of a Sample
A centrifuge layering insert configured for insertion into a centrifuge tube includes a tube having a first open end and a second open end. The centrifuge...
BIOMASS CARRIER AND A METHOD OF MANUFACTURING THEREOF
A compressible biomass carrier for use in fluid treatment systems is disclosed. The biomass carrier includes an extruded circumferential mesh-like structure...
Membrane Biofilm Reactors, Systems, and Methods for Producing Organic
The present disclosure is directed toward membrane biofilm reactors primarily comprising microorganisms that produce chemical fuel products or precursors...
Apparatus and Methods for Cell Culture
A bioreactor (1) for the culture of cells (C) comprising a stack of carriers (7) for cell (C) adherence and liquid medium (M) distribution. The carriers (7)...