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Patent # Description
2017/0027932 TREATMENT OF CANCER WITH TOR KINASE INHIBITORS
Provided herein are methods for treating or preventing a solid tumor, non-Hodgkin lymphoma or multiple myeloma in a patient, comprising administering an...
2017/0027931 POSACONAZOLE PHARMACEUTICAL COMPOSITIONS AND PREPARATION METHODS, USES AND PHARMACEUTICAL FORMULATIONS THEREOF
The present invention relates to a pharmaceutical composition comprising posaconazole and a carrier material, wherein the carrier material comprises a...
2017/0027930 METHODS FOR THE TREATMENT OF PEDIATRIC OTIC DISORDERS
Disclosed herein are methods for the treatment of pediatric otic diseases or conditions with antimicrobial agent compositions and formulations administered...
2017/0027929 MEDICAL USE OF ARTEMISININ COMPOUNDS AND GEPHYRIN AGONISTS
The invention refers to BTBD9 binders and gephyrin binders for medical use and in particular an artemisinin compound of general formula I for use in the...
2017/0027928 CAMKK-BETA AS A TARGET FOR TREATING CANCER
Provided herein are compounds, compositions, including pharmaceutical compositions, having anti-cancer activity. Also provided are methods for diagnosing,...
2017/0027927 Treatment of Glaucoma Using Laquinimod
The subject invention provides a method of treating a subject afflicted with glaucoma, suffering from retinal ganglion cell (RGC) loss or damage, or elevated...
2017/0027926 COMPOSITIONS AND METHODS OF INHIBITING HISTONE DEACETYLASES
The present invention provides compositions and methods for treating pulmonary hypertension. In one aspect, a method is included for increasing myocyte...
2017/0027925 PIPERIDINONE CARBOXAMIDE AZAINDANE CGRP RECEPTOR ANTAGONISTS
The present invention is directed to piperidinone carboxamide azaindane derivatives which are antagonists ofCGRP receptors and useful in the treatment or...
2017/0027924 PHARMACEUTICAL COMPOSITION CONTAINING NICOTINIC ACID AND/OR NICOTINAMIDE FOR BENEFICALLY INFLUENCING BLOOD...
The present invention relates to a new pharmaceutical composition containing nicotinic acid and/or nicotinamide and/or related compounds for beneficially...
2017/0027923 METHODS USING 3-(4-AMINO-1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PIPERIDINE-2,6-DIONE FOR TREATMENT OF MANTLE...
Methods of treating, preventing or managing mantle cell lymphomas are disclosed. The methods encompass the administration of an immunomodulatory compound of...
2017/0027922 USE OF NARATRIPTAN IN THE TREATMENT OF ROSACEA
Described herein is a method of using a topical, pharmaceutical composition, particularly a dermatological composition, comprising naratriptan to treat rosacea...
2017/0027921 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND
The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as an agent for the...
2017/0027920 Compositions and Methods for Prophylaxis and Treatment of Addictions
The present invention relates to methods of treating or preventing addiction and relapse use of addictive agents, and treating or preventing addictive or...
2017/0027919 Method for the Treatment of Neurological Disorders by Enhancing the Activity of Beta-Glucocerebrosidase
Provided is a method of increasing the stability of wild-type .beta.-glucocerebrosidase. Also provided are methods of treating and/or preventing an individual...
2017/0027918 ANTITUSSIVE COMPOSITIONS AND METHODS
Disclosed herein are compositions which include nicotinic receptor agonists, specifically of the .alpha.7 nAChR subtype, and methods for suppressing cough.
2017/0027917 PHARMACEUTICAL COMPOSITIONS COMPRISING ANTIBACTERIAL AGENTS
Pharmaceutical compositions comprising ceftolozane or a pharmaceutically acceptable derivative, and a compound of Formula (I) or a stereoisomer or a...
2017/0027916 FACTOR IXa INHIBITORS
In its many embodiments, the present invention provides a novel class of benzamide compounds represented by Formula (I) or pharmaceutically acceptable salts or...
2017/0027915 TREATMENT OF AUTOIMMUNE DISORDERS AND INFECTIONS USING ANTAGONISTS OF SGK1 ACTIVITY
The present invention provides novel methods for treating Th2-mediated immune disorders and enhancing Th1-mediated immune responses in a subject comprising...
2017/0027914 NOVEL ANTI-AGING AGENTS AND METHODS TO IDENTIFY THEM
The present invention discloses novel mechanisms in the aging process and describes novel methods for high-throughput screening to identify, detect, and purify...
2017/0027913 COMPOSITIONS FOR AN ORALLY ACTIVE 1,2,4-OXADIAZOLE FOR THE TREATMENT OF DISEASE
The present invention relates to specific doses of and dosing regimens for using a 1,2,4-oxadiazole benzoic acid compound in treating or preventing diseases...
2017/0027912 SUBSTITUTED 5-(3,5-DIMETHYLISOXAZOL-4-YL)INDOLINE-2-ONES
Disclosed are substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-one compounds, pharmaceutical compositions comprising at least one such 4 substituted...
2017/0027911 FORMULATIONS OF DEFERASIROX AND METHODS OF MAKING THE SAME
The disclosure provides for improved pharmaceutical compositions containing deferasirox (DFX) and methods of manufacturing the same. In particular, the...
2017/0027910 FORMULATIONS OF ENZALUTAMIDE
This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.
2017/0027909 COMBINATIONS OF THERAPEUTIC AGENTS FOR TREATING CANCER
The invention relates to a combination comprising the N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)-ethyl]-amino]methyl]phenyl]-- 2E-2-propenamide; and one or...
2017/0027908 Pharmaceutical Composition
Described herein are pharmaceutical compositions for inhalation comprising glycopyrrolate, a beta.sub.2-agonist, and optionally an inhaled corticosteroid; to a...
2017/0027907 SIP MODULATOR IMMEDIATE RELEASE DOSAGE REGIMEN
The present invention relates to siponimod (BAF312) for use in the treatment of an autoimmune disease, wherein an immediate release dosage form is administered...
2017/0027906 IMMUNOSUPPRESSANT FORMULATION
The present invention concerns a dosage form, preferably for immediate release, comprising siponimod, a moisture-protective-agent and further pharmaceutical...
2017/0027905 ANTI-INFLAMMATORY AGENTS AS VIROSTATIC COMPOUNDS
The present invention relates to compounds of the general formula (I) and salts and physiologically functional derivatives thereof, for use in the treatment of...
2017/0027904 COMPOSITION AND METHOD TO TREAT AND ALLEVIATE SYMPTOMS OF HOT FLASHES IN A FEMALE SUBJECT
A dietary supplement composition is formulated in a therapeutic amount to treat and alleviate symptoms of hot flashes in a female subject, such as experiencing...
2017/0027903 USE OF DELTA TOCOPHEROL FOR THE TREATMENT OF LYSOSOMAL STORAGE DISORDERS
This disclosure relates generally to the treatment of lysosomal storage disorders. Specifically, the disclosure relates to a novel use of .delta. tocopherol in...
2017/0027902 Use of a Composition Comprising a Flavonol, A Flavonoid, and a Fatty Acid in the Treatment of Oxidative...
Compositions comprising a flavan-3-ol, a flavonoid, and a fatty acid have been demonstrated to mitigate the oxidative damage arising from mitochondrial...
2017/0027901 USE OF NOBILETIN IN CANCER TREATMENT
The present invention discloses a pharmaceutical composition of treating multidrug resistance cancer, comprising a citrus methoxyflavone and a chemotherapeutic...
2017/0027900 USE OF TANGERETIN IN CANCER TREATMENT
The present invention discloses a pharmaceutical composition of treating multidrug resistance cancer, comprising a citrus methoxyflavone and a chemotherapeutic...
2017/0027899 USE OF MALONONITRILE COMPOUNDS FOR PROTECTING ANIMALS FROM PARASITES
The present invention provides uses of aryl alkyl malononitrile compounds of formula (I), or veterinarily acceptable salts thereof, for controlling and...
2017/0027898 FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE
Fumarate compounds, pharmaceutical compositions comprising the fumarate compounds, and methods of using fumarate compounds and pharmaceutical compositions for...
2017/0027897 mTORC1 MODULATION BY AMINO ACIDS AND USES THEREOF
Disclosed herein are methods for modulating mTORC1 activation in cells or a subject, and related compositions, kits, and agents for use in those methods. Also...
2017/0027896 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VASCULAR MALFORMATION
An inhibitor of Wnt/.beta.-catenin signaling for use in the treatment and/or prevention of a pathology having vascular malformation is provided. The inhibitor...
2017/0027895 Compositions and Methods for Treating Severe Pain
The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a...
2017/0027894 SYSTEMS AND METHODS FOR BIO-MATCHING GELS, CREAMS AND LOTIONS
A method of bio-matching a topical gel, cream or lotion may comprise selecting a vagina of a living body, identifying a secretion of the selected vagina,...
2017/0027893 THIOSEMICARBAZONES INHIBITORS OF LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE AND USES THEREOF
Lysophosphatidic acid acyltransferase-beta (LPAAT-.beta.) catalyzes the production of phosphatidic acid (PA) from lysophosphatidic acid (LPA). The lipid...
2017/0027892 Compositions and methods for combination pharmacological treatments to induce a prolonged, mild decrease in...
The present invention is directed to combination pharmacological treatments that induce a prolonged, modest decrease in core body temperature, to the range of...
2017/0027890 SELECTIVE INHIBITORS OF UNDIFFERENTIATED CELLS
Uses of a compound of any of Formulas I-VI as a cytotoxic inhibitor of undifferentiated cells are disclosed herein, as well as pharmaceutical compositions...
2017/0027889 USE OF CATECHOLAMINES AND RELATED COMPOUNDS AS ANTI-ANGIOGENIC AGENTS
The present invention provides a method for inhibiting angiogenesis in a human subject in need of such inhibition. The method comprises administering to the...
2017/0027888 USE OF CATECHOLAMINES AND RELATED COMPOUNDS AS ANTI-ANGIOGENIC AGENTS
The present invention provides a pharmaceutical composition comprising at least one compound selected from the group consisting of (S)-isoproterenol,...
2017/0027887 COMPOSITIONS AND METHODS FOR TREATING OPIOID RECEPTOR ASSOCIATED DISEASES
The invention relates to dezocine compositions and uses thereof. Specifically, the invention relates to dezocine compositions, including nano-dezocine...
2017/0027886 Abuse-proofed dosage forms
The invention relates to a form of administration which is secured against misuse and which is thermoformed without extrusion, comprising at least one...
2017/0027885 1-AMINOCYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF COCHLEAR TINNITUS
The present invention relates to the treatment of an individual afflicted with tinnitus associated with hearing loss comprising administering to the individual...
2017/0027884 Astaxanthin Anti-Inflammatory Synergistic Combinations
Compositions having synergistic combinations of astaxanthin with a tomato extract lycopene, and optionally with carnosic acid and/or lutein. Compositions...
2017/0027883 METHOD FOR ADJUNCTIVE TREATMENT OF CANCER METASTASIS BY USING LYCOGEN
The present invention relates to a method for adjunctive treatment of cancer by using a Lycogen composition to inhibit metastasis, comprising administering a...
2017/0027882 CoQ10 (Ubiquinone, Ubiquinol), Vitamin A (Retinoid Acid, Retinol), Vitamin E (Tocotrienol, Tocopherol) and...
CoQ10 and vitamin E are both lipid-soluble nutrients with redox potential. Tocopherol and/or tocotrienol protect CoQ10 from oxidative damage and reduce...
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