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Patent # Description
2017/0037197 METHODS OF PREPARING METAL NANODENDRIMER STRUCTURES
A method includes heating a sulfonated polyester resin in an organic-free solvent, adding a solution of silver (I) ion to the heated resin in water to form a...
2017/0037194 Oil soluble rheology modifying star macromolecules
Oil soluble rheology modifying star macromolecules having a core and five or more polymeric arms, and compositions comprising the same. The polymeric arms on a...
2017/0037191 RAPID-CURING, MIGRATION-FREE COMPOSITION BASED ON ORGANIC POLYMERS CONTAINING SILANE GROUPS
The invention relates to a composition comprising at least one organic polymer that contains silane groups and at least one catalyst of formula (I). The...
2017/0037188 Hydroxide-Stable Ionenes
Described herein are stable hydroxide ion-exchange polymers. The polymers include ionenes, which are polymers that contain ionic amines in the backbone. The...
2017/0037179 SHEET-FORMING BODY, ADHESIVE SHEET, AND LAMINATE
The present invention provides a sheet-forming body containing a thiourethane bond-having compound and a thiol group-having compound, wherein, in an IR...
2017/0037178 BLOCK COPOLYMER AND ASSOCIATED PHOTORESIST COMPOSITION AND METHOD OF FORMING AN ELECTRONIC DEVICE
A block copolymer useful in electron beam and extreme ultraviolet photolithography includes a first block with units derived from a base-solubility-enhancing...
2017/0037173 Photoalignment Materials Having Improved Adhesion
The present disclosure provides for new photoalignment (co)polymer materials which demonstrate improved adhesion to a substrate. The (co)polymeric structure...
2017/0037168 METHOD FOR PRODUCING ETHYLENE-VINYL ESTER COPOLYMER, AND SAPONIFIED ETHYLENE-VINYL ESTER COPOLYMER PRODUCT
The present invention provides a saponified ethylene-vinyl ester copolymer product from which a film having reduced fish eyes can be obtained and a method for...
2017/0037158 Long Chain Branched Polymers and Methods of Making Same
A polymer having a long chain branching content peaking at greater than about 20 long chain branches per million carbon atoms, and a polydispersity index of...
2017/0037151 ANTI-PSYK ANTIBODY MOLECULES AND USE OF SAME FOR SYK-TARGETED THERAPY
The invention relates to antibody molecules which bind pSYK, and methods for using the same for diagnosis, prognosis, to select patients for treatment with a...
2017/0037145 ANTIBODY THAT BINDS ERBB-2 AND ERBB-3
The invention relates among others to antibodies comprising a first antigen-binding site that binds Erb B-2 and a second antigen-binding site that binds Erb...
2017/0037144 Anti-MCAM Antibodies And Associated Methods Of Use
Described herein are anti-MCAM antibodies and antigen binding fragments thereof that are capable of inhibiting the interaction between MCAM and its ligand, a...
2017/0037143 TARGETED THERAPY TO RESTORE RADIOACTIVE IODINE TRANSPORT IN THYROID CANCER
The invention includes method, pharmaceutical compositions and uses thereof for treating patients with Papillary Thyroid Carcinoma (PTC) using a Platelet...
2017/0037142 METHODS OF TREATING PROSTATE CANCER WITH ANTI-PROSTATE SPECIFIC MEMBRANE ANTIGEN ANTIBODIES
Modified antibodies, or antigen-binding fragments thereof, to the extracellular domain of human prostate specific membrane antigen (PSMA) are provided. The...
2017/0037138 TRANSGENIC ANIMALS PRODUCING MONOVALENT HUMAN ANTIBODIES AND ANTIBODIES OBTAINABLE FROM THESE ANIMALS
The invention relates to novel non-human transgenic animals, which upon antigenic stimulation are capable of producing monovalent antibodies binding to a...
2017/0037136 Anti-CD154 antibodies and methods of using them
The present invention relates to antagonistic antibodies specifically binding CD154, polynucleotides encoding the antibodies or fragments, and methods of...
2017/0037133 IMMUNE-CHECKPOINT INHIBITORS FOR USE IN THE TREATMENT OF BLOOD-BORNE CANCERS
The present invention provides an inhibitor against CD112 (Nectin-2, PVRL2), CD155 (PVR), Galectin-9, TIM-3 and/or TIGIT for use in a method of treatment of a...
2017/0037130 ANTIBODY CONSTRUCTS FOR DLL3 AND CD3
The present invention relates to a bispecific antibody construct comprising a first binding domain which binds to human DLL3 on the surface of a target cell...
2017/0037124 ANTI-ANGPTL8 ANTIBODIES AND USES THEREOF
The present invention provides antibodies that bind to ANGPTL8 and methods of using the same. According to certain embodiments, the antibodies of the invention...
2017/0037114 PROTEINS WITH REPETITIVE BACTERIAL-IG-LIKE (BIG) DOMAINS PRESENT IN LEPTOSPIRA SPECIES
The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive...
2017/0037113 Binding Molecule Having Influenza A Virus-Neutralizing Activity Produced from Human B Cell
The present invention relates to a binding molecule having influenza A virus-neutralizing activity derived from a human B cell, and the binding molecule having...
2017/0037109 Fibronectin Binding Domains with Reduced Immunogenicity
Fibronectin type III (.sup.10Fn3) binding domains having novel designs that are associated with reduced immunogenicity are provided. The application describes...
2017/0037107 Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2017/0037105 PEPTIDOMIMETIC MACROCYCLES
The present invention provides peptidomimetic macrocycles capable of modulating growth hormone levels and methods of using such macrocycles for the treatment...
2017/0037100 METHODS FOR TREATING MYELOPROLIFERATIVE DISORDERS
In part, the present disclosure relates methods for treating, preventing, or reducing the severity of a myeloproliferative disorder (e.g., polycythemia vera,...
2017/0037096 Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2017/0037095 Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2017/0037092 Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2017/0037091 STY PEPTIDES FOR INHIBITION OF ANGIOGENESIS
Peptides for the treatment of cancer and angiogenic disorders are provided. In some aspects, the peptides may be used to decrease angiogenesis or VEGF...
2017/0037089 NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST PROSTATE CANCER AND OTHER CANCERS
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2017/0037074 METHOD OF ESTERIFICATION OF CARBOXYL GROUPS PRESENT ON MULTIHYDROXYL CYCLIC POLYENE MOLECULAR STRUCTURES...
Disclosed is a process for the preparation of partricin alkyl esters which involves reacting partricin in a solvent with primary alkyl alcohols in the quantity...
2017/0037073 RECTANGULAR PARALLELEPIPEDAL MALTITOL
The invention concerns maltitol crystals, characterized in that they have a rectangular parallelepipedal shape and have a length to width dimensional ratio in...
2017/0037070 ARSENOPLATIN ANTI-CANCER AGENTS
Disclosed herein are conjugates that include a ligand, and a compound having the structure of formula (I) ##STR00001## M is Pt, Pd or Ni; Q is As, Sb or Bi;...
2017/0037065 BRANCHED SILOXANES AND METHODS FOR SYNTHESIS
The present invention describes branched and functionalized siloxanes and methods for making such compounds. The compounds have a variety of uses. One...
2017/0037059 GYRASE INHIBITORS
Novel gyrase inhibitors and related compositions and methods are useful for impeding bacterial growth. Compounds of Formula (I), are disclosed: Formula (I),...
2017/0037056 Iminothiadiazepane Dioxide Compounds as BACE Inhibitors, Compositions, and Their Use
In its many embodiments, the present invention provides certain iminothiadiazepane dioxide compounds, including compounds Formula (I): ##STR00001## or a...
2017/0037054 Method For Preparing Spherical Clopidogrel Hydrogen Sulfate Polymorph I
This invention provides a new preparation method of Clopidogrel Hydrogen Sulfate spherical crystal form I, using single 2-butanol as solvent, controlling the...
2017/0037050 ISOQUINOLINESULFONYL DERIVATIVE AS RHO KINASE INHIBITOR
The present invention discloses a class of isoquinolinesulfonyl derivatives as RHO kinase inhibitors, and pharmaceutical compositions thereof, and relates to...
2017/0037049 HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS
The present invention provides, in part, compounds of Formula (I): and pharmaceutically acceptable salts thereof; processes for the preparation of;...
2017/0037048 ORGANIC COMPOUNDS
The invention relates to particular substituted heterocycle fused gamma-carbolines, their prodrugs, in free, solid, pharmaceutically acceptable salt and/or...
2017/0037035 COMPOUND
This invention relates to a compound, as defined in the specification, useful in the treatment of mycoses, compositions containing it and its use in therapy.
2017/0037034 JAK1 Inhibitors
The present invention relates to certain benzimidazole compounds, or pharmaceutically acceptable salts thereof, that inhibit Janus kinase 1 (JAK1),...
2017/0037033 OXOPIPERAZINE HELIX MIMETICS AS INHIBITORS OF THE p53-MDM2 INTERACTION
The present invention relates to oligooxopiperzines for modulating the p53-Mdm2 interaction. Methods of using the oligooxopiperazines are also disclosed.
2017/0037027 NOVEL MANUFACTURING PROCESS FOR TRIAZINE, PYRIMIDINE AND PYRIDINE DERIVATIVES
The invention relates to a method of manufacturing triazine, pyrimidine and pyridine derivatives of formula (I), wherein U, V, W and Z are nitrogen or carbon...
2017/0037026 TRIAZOLE AGONISTS OF THE APJ RECEPTOR
Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the...
2017/0037015 NOVEL PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF
The present invention relates to novel compounds of general formula: ##STR00001## and to the cosmetic or pharmaceutical use thereof.
2017/0037014 FUNGICIDAL PYRAZOLES
Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, ##STR00001## wherein Q.sup.1, X, R.sup.1,...
2017/0037009 PYRIDONE AMIDES AS MODULATORS OF SODIUM CHANNELS
The invention relates to pyridone amide compounds of formula I and I' or pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels: ...
2017/0036996 HYDROXAMIC ACIDS AND USES THEREOF
Compounds of formula I are provided: ##STR00001## R.sub.1 is an alkoxy or O(CH.sub.2).sub.pX, p is an integer from 2 to 3 and X is OH, NH.sub.2, or CO.sub.2H, m...
2017/0036993 METAL-ORGANIC FRAMEWORK FOR FLUID STREAM FILTRATION APPLICATIONS
The present invention relates to a porous metal-organic framework (MOF) and includes a process for making the MOF and a process for using the MOF to remove...
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