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Patent # Description
2017/0042900 PREVENTIVE AND/OR THERAPEUTIC AGENT OF IMMUNE DISEASE
Provided is a preventive and/or therapeutic agent for immune diseases containing a compound having a BTK inhibitory activity or a salt thereof, as an active...
2017/0042899 Use of Tetrahydrobiopterine Derivatives in the Treatment and Nutrition of Patients With Amino Acid Metabolic...
The invention relates to the use of tetrahydrobiopterine and the derivatives thereof in the production of a medicament to improve protein tolerance for the...
2017/0042898 METHODS AND COMPOSITIONS FOR TREATING VIRAL OR VIRALLY-INDUCED CONDITIONS
Provided are methods and compositions for the prevention and/or treatment of viral conditions, virally-induced conditions and inflammatory conditions. The...
2017/0042897 TRIAZOLE AGONISTS OF THE APJ RECEPTOR
Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the...
2017/0042896 CERDULATINIB FOR TREATING MYELOMA
Compositions and methods for treating multiple myeloma (MM), acute myeloid lymphoma (AML) or a myeloproliferative disease (MPD) in a human patient in need...
2017/0042895 Combination Treatment Comprising Administration of 2-Amino-3,5,5-trifluoro-3,4,5,6-tetrahydropyridines
The present invention is directed to the combined use of BACE1 inhibitor of Formula I ##STR00001## and a compound useful in active or passive Tau immunotherapy,...
2017/0042894 Methods Of Treating Dyskinesia And Related Disorders
The present disclosure describes compounds and pharmaceutically acceptable salts, thereof and compositions and formulations comprising the same that are useful...
2017/0042893 USE OF CASEIN KINASE I INHIBITORS FOR DEPLETING STEM CELLS
A method of treating cancer in a subject is disclosed. The method comprises administering to the subject a therapeutically effective amount of a Casein kinase...
2017/0042892 HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use. ##STR00001##
2017/0042891 AXL INHIBITORS FOR USE IN COMBINATION THERAPY FOR PREVENTING, TREATING OR MANAGING METASTATIC CANCER
This invention is directed to methods of preventing, treating or managing cancer, preferably metastatic cancer, in a patient. The methods comprise ...
2017/0042890 METHODS OF REDUCING DECLINE IN VITAL CAPACITY
Provided herein are compositions and methods for reducing the decline in vital capacity in a subject by administering to the subject a skeletal muscle troponin...
2017/0042889 AMINO PYRAZINE DERIVATIVES AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS
The present invention provides compounds of formula (I) which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases...
2017/0042888 GLYT1 INHIBITORS FOR USE IN THE TREATMENT OF HEMATOLOGICAL DISORDERS
The invention is related to compounds, which are GlyT1 inhibitors, for use in the treatment of hematological disorders, in particular for use in the treatment...
2017/0042887 Combination of Brexpiprazole and Nalmefene and Use Thereof for Treating Substance-Related Disorders
A medicament comprising (I) brexpiprazole or a pharmaceutically acceptable salt thereof, and (II) nalmefene or a pharmaceutically acceptable salt thereof in...
2017/0042886 PROCASPASE COMBINATION THERAPY FOR GLIOBLASTOMA
The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods...
2017/0042885 Treating Pain In Patients With Hepatic Impairment
An extended release composition for an analgesic active pharmaceutical ingredient which may be an opioid, preferably hydrocodone as the only active ingredient....
2017/0042884 LIQUID BUPRENORPHINE FORMULATIONS
The invention provides liquid formulations containing buprenorphine, a pharmaceutically acceptable salt thereof, or a derivative thereof. The invention further...
2017/0042883 Methods for Detecting and Treating Rhinovirus Infection
The invention provides a method for evaluating the activity of an agent for treating rhinovirus infection or a symptom thereof, a method of detecting or...
2017/0042882 Selective Opioid Compounds
The present invention relates to compounds of Formula I or II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: ##STR00001## which relates to...
2017/0042881 TREATMENT OF H-RAS-DRIVEN TUMORS
The present disclosure describes a compositions and methods for treatment of Hras-driven cancers. Administration of a farnesyltransferase inhibitor, for...
2017/0042880 Method of Treating Lung Adenocarcinoma
This invention is directed to the treatment of cancer in a patient, particularly a patient with lung adenocarcinoma, and more particularly a patient with...
2017/0042879 TABLETTABLE CHEWING GUMS
The invention relates to certain nicotine chewing gums that provide for a high rate of buccal absorption and high plasma concentrations, in particular over the...
2017/0042878 COMPOSITIONS COMPRISING SCOPOLAMINE AND KETAMINE IN THE TREATMENT OF DEPRESSION
Described are compositions and methods for administering scopolamine and ketamine in the treatment of depression (e.g., Major Depressive Disorder and...
2017/0042877 COMPOSITIONS AND METHODS FOR TREATING SCHIZOPHRENIA
The disclosure provides a novel polymorph of Compound (I): ##STR00001## 2-((1-(2-(4-Fluorophenyl)-2-oxoethyl)piperidin-4-yl)methyl)isoindolin-1-o- ne...
2017/0042876 METHODS FOR THE TREATMENT OF PARKINSON'S DISEASE PSYCHOSIS USING PIMAVANSERIN
Methods for the treatment of Parkinson's disease psychosis which comprise the administration of pimavanserin.
2017/0042875 NOVEL ACETIC ACID ESTER COMPOUND OR SALT THEREOF
An acetic acid ester compound represented by the following formula (I) or a salt thereof, ##STR00001## wherein R represents optionally substituted deuterated...
2017/0042874 Orally Effective Methylphenidate Extended Release Powder and Aqueous Suspension Product
An oral methylphenidate powder which is reconstitutable into a final oral aqueous sustained release formulation containing at least about 50%, or at least...
2017/0042873 ORALLY EFFECTIVE METHYLPHENIDATE EXTENDED RELEASE POWDER AND AQUEOUS SUSPENSION PRODUCT
An oral methylphenidate powder which is reconstitutable into a final oral aqueous sustained release formulation containing at least about 50%, or at least...
2017/0042872 TRIAZOLE AGONISTS OF THE APJ RECEPTOR
Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the...
2017/0042871 TRIAZOLE AGONISTS OF THE APJ RECEPTOR
Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the...
2017/0042870 TARGETED NANOPARTICLE COMPOSITIONS AND METHODS OF THEIR USE TO TREAT OBESITY
Nanoparticles having a positive feedback delivery system include an agent specific for a target in combination with a target inducing agent. Upon ...
2017/0042869 Methods for limiting acute kidney injury
Method of limiting development of acute kidney injury (AKI) and treating AKI using pyridoxamine are described, together with methods for monitoring efficacy of...
2017/0042868 Methods for Treatment of Fabry Disease
Provided are in vitro and in vivo methods for determining whether a patient with Fabry disease will respond to treatment with a specific pharmacological...
2017/0042867 THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF
Human therapeutic treatment compositions comprise at least two of a curcumin component, a harmine component, and an isovanillin component, and preferably all...
2017/0042866 THERAPEUTIC COMPOSITIONS CONTAINING HARMINE AND ISOVANILLIN COMPONENTS, AND METHODS OF USE THEREOF
Human therapeutic treatment compositions comprise at least two of a curcumin component, a harmine component, and an isovanillin component, and preferably all...
2017/0042864 METHODS OF TREATING HEPATIC ENCEPHALOPATHY
The application describes treatment of hepatic encephalopathy using gastrointestinal specific antibiotics. One example of a gastrointestinal specific...
2017/0042863 METHODS OF SEDATION DURING CRITICAL CARE TREATMENT
Methods of sedating a patient undergoing critical care treatment using intravenous gaboxadol are provided.
2017/0042862 TREATMENT OF HEPATITIS DELTA VIRUS INFECTION
Methods of reducing hepatitis delta virus (HDV) viral loads in a patient are provided. In some embodiments, the method comprises treating the patient with...
2017/0042861 Sublingual Ondansetron Spray
The invention is directed to sublingual spray formulations containing ondansetron, a pharmaceutically acceptable salt thereof, and a solvent consisting of...
2017/0042860 METHODS AND MATERIALS FOR USING RUMINOCOCCUS GNAVUS OR CLOSTRIDIUM SPOROGENES TO TREAT GASTROINTESTINAL DISORDERS
This document provides materials and methods related to bacterial compositions containing at least one bacterial organism having tryptophan decarboxylase...
2017/0042859 COMPOSITIONS AND METHODS FOR TREATING ALOPECIA
The present invention is directed to a composition for treating alopecia containing minoxidil, cyclosporine A and a compound that binds FK506 binding protein 4...
2017/0042858 MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME
The present invention provides novel conformationally-defined macrocyclic compounds that can function as selective modulators of the ghrelin receptor (growth...
2017/0042857 SYNAPTOJANIN-2 INHIBITORS FOR USE IN THE TREATMENT OF CANCER
Disclosed herein are synaptojanin-2 inhibitors, and novel methods and uses utilizing same for preventing tumor metastasis, treating cancer or inhibiting...
2017/0042856 METHOD AND COMPOSITION FOR TREATING ACNE
The subject invention provides a method of treating acne in a subject which comprises topically and periodically applying to the subject's acne a composition...
2017/0042855 NANOPARTICLES COMPRISING DOCETAXEL FOR TREATING CANCERS HAVING A K-RAS MUTATION
The present disclosure relates in part to methods of treating cancers having a mutation in a Ras gene in a patient in need thereof, comprising administering to...
2017/0042854 COMPOSITION CONTAINING MONOACETYLDIGLYCERIDE COMPOUND AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CHRONIC...
The present invention relates to a pharmaceutical composition containing a monoacetyldiacylglycerol compound as an active ingredient for preventing or treating...
2017/0042853 CRYSTALLINE FORMS OF (N,N-DIETHYLCARBAMOYL)METHYL METHYL (2E)BUT-2-ENE-1,4-DIOATE, METHODS OF SYNTHESIS AND USE
Disclosed herein are crystalline forms of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, which is a prodrug of methyl hydrogen fumarate....
2017/0042852 PREPARATION FOR IMPROVING THE ACTION OF RECEPTORS
The present invention relates to the use of polyunsaturated fatty acids and one or more components which have a beneficial effect on total methionine...
2017/0042851 METHOD OF DESTROYING AND PREVENTING BACTERIAL AND FUNGAL BIOFILM BY AMINO ACID INFUSION
Disclosed is a method comprising the administration of a 3% amino acid and 3% glycerin solution for the use of prevention and disruption of bacterial biofilms....
2017/0042850 Acetylcysteine Composition and Uses Thereof
This invention relates to novel acetylcysteine compositions in solution, comprising acetylcysteine and which are substantially free of metal chelating agents,...
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