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Patent # Description
2017/0049804 FAST ACTING JOINT RELIEF FORMULATIONS
The instant invention provides a method and composition for treating or preventing osteoarthritis, joint effusion, joint inflammation and pain, synovitis,...
2017/0049803 Glycosaminoglycan Composition and Method of Use for Kidney Stone Removal
The invention provides compositions and methods of use thereof, in conjunction with the treatment and prevention of kidney and ureteral stones and related...
2017/0049802 METHODS AND COMPOSITIONS FOR TREATING ROSACEA
There is provided a method for treating rosacea comprising a composition which comprises at least one oxidant, at least one photoactivator capable of...
2017/0049801 MULTIBLOCK COPOLYMERS
Provided herein are multiblock copolymers, as well as micelles and therapeutic compositions thereof.
2017/0049800 PHARMACEUTICAL COMBINATION COMPRISING A CIP2A SILENCING AGENT FOR USE IN THE TREATMENT OF A HYPERPROLIFERATIVE...
The invention is based on a finding that silencing CIP2A (KIAA1524) gene sensitizes cancer cells for apoptosis-inducing activity of certain small molecule...
2017/0049799 OPHTHALMIC FORMULATIONS
The present invention relates to an ophthalmic formulation which comprises a fine particle of Compound A in an aqueous suspension and a manufacturing process...
2017/0049798 Maintenance of Platelet Inhibition During Antiplatelet Therapy
A method for reducing or maintaining platelet inhibition in a patient by administering cangrelor prior to an invasive procedure is described. The method of...
2017/0049797 COMBINATION THERAPY FOR TREATING HCV INFECTION
The present invention relates to therapeutic combinations comprising faldaprevir, sofosbuvir, ledipasvir and, optionally, ribavirin, and methods of using such...
2017/0049796 ADMINISTRATION OF CITICOLINE TO IMPROVE COGNITIVE PERFORMANCE, ATTENTIONAL PERFORMANCE, AND MOTOR FUNCTION
A method of improving both motor function and cognitive function of healthy human subjects through administration of citicoline or its salt in high dosage or...
2017/0049795 Composition and Methods Of Treating Acne And Photoaging
Pharmaceutical compositions comprising a first anti-acne compound, a second anti-acne compound, and an anti-photoaging compound are described. Methods for the...
2017/0049794 PDIA4 PROTEIN AS A TARGET FOR DIAGNOSIS, MONITORING AND TREATMENT OF DIABETES
A Pdia4 inhibitor for use in preventing, alleviating and/or treating diabetes and/or diabetes-related complications in a subject in need thereof is disclosed,...
2017/0049793 MOLECULAR ACTIVATORS OF THE WNT/BETA-CATENIN PATHWAY
The present invention is directed toward a method of treating a subject for a condition mediated by aberrant Wnt/.beta.-catenin signaling by selecting a...
2017/0049792 USE OF GINSENOSIDE M1 FOR TREATING LUPUS NEPHRITIS
The present invention provides a method of treating a subject afflicted with lupus nephritis comprising administering to the subject an amount of ginsenoside...
2017/0049791 COMPOSITIONS FOR ORAL ADMINISTRATION OF ZOLEDRONIC ACID OR RELATED COMPOUNDS FOR TREATING COMPLEX REGIONAL PAIN...
Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, can be used to treat or alleviate pain or related conditions such as...
2017/0049790 COMBINATION THERAPIES TARGETING MITOCHONDRIA FOR CANCER THERAPY
Pharmaceutical compositions for the treatment of cancer are provided. In one embodiment the composition comprises Gamitrinib and a P13K inhibitor selected from...
2017/0049789 TOPICAL FILM DELIVERY SYSTEM
The described invention provides a topical bioadhesive film-forming pharmaceutical composition formulated for application directly to skin or to a substrate....
2017/0049788 Abiraterone Steroid Formulation
A nanoparticulate composition of abiraterone acetate that allows treatment at a lower dose than convention abiraterone acetate formulations is described as in...
2017/0049787 Derivatives of Ergostatrien-3-Beta-OL From Antrodia Camphorata and Antiglycemic, Antihyperlipidemic and...
The present invention provides a method for treating diabetes, hyperlipidemia or hepatic total lipids by using ergostatrien-3.beta.-ol and its derivatives, as...
2017/0049786 MTOR PATHWAY INHIBITORS FOR TREATING OCULAR DISORDERS
Diseases and conditions associated with tissues of the body, including but not limited to tissues in the eye, can be effectively treated, prevented, inhibited,...
2017/0049785 ESTROGEN COMBINATION FOR TREATMENT OF MULTIPLE SCLEROSIS
Provided are methods for treating multiple sclerosis using a continuous regimen of estrogen in combination with periodic administration of a progestogen.
2017/0049784 METHOD OF TREATING ACUTE MYELOID LEUKEMIA AND/OR ACUTE LYMPHOBLASTIC LEUKEMIA USING THIENOTRIAZOLODIAZEPINE...
A method of treating acute myeloid leukemia, acute lymphoblastic leukemia, high risk myelodysplastic syndrome, and/or HR-MDS/AML in a mammal by administering a...
2017/0049783 METHODS OF TREATING DISORDERS ASSOCIATED WITH PROTEIN POLYMERIZATION
The present invention relates to methods of treatment of clinical disorders associated with protein polymerization comprising administering, to a subject, an...
2017/0049782 ACTIVE INGREDIENT (I) CONTAINING COMPOSITION AND METHOD FOR PREPARING SAME
The present invention relates to a composition comprising 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin- -5-yl}-methyl]-2-thiophene...
2017/0049781 HSP90 INHIBITOR COMBINATIONS
A Pharmaceutical combination comprising and Hsp90 inhibitor an mTOR inhibitor, and methods of using the combination to treat or prevent proliferative disorders.
2017/0049780 USE OF (2R, 6R)-HYDROXYNORKETAMINE, (S)-DEHYDRONORKETAMINE AND OTHER STEREOISOMERIC DEHYDRO AND HYDROXYLATED...
The disclosure provides pharmaceutical preparations containing (2R,6R)-hydroxynorketamine, or (R)- or (S)-dehydronorketamine, or other stereoisomeric dehydro...
2017/0049779 FLAGELLAR AND NEEDLE COMPLEX (INJECTOSOME) LOOP AS ANTI BACTERIAL DRUG TARGET
The present invention relates to a method for screening a compound that inhibits secretion of toxins into host-cell cytoplasm by virulent bacteria using a...
2017/0049778 TREATMENT OF ERECTILE DYSFUNCTION AND OTHER INDICATIONS
The present invention generally relates to the transdermal delivery of various compounds. In some aspects, transdermal delivery may be facilitated by the use...
2017/0049777 COMPOSITIONS, METHODS AND USES FOR THE TREATMENT OF DIABETIC NEUROPATHIES
The present invention relates to compositions and methods for the treatment of diabetic neuropathies. More particularly, this invention relates to compositions...
2017/0049776 Sildenafil Solutions and Methods of Making and Using Same
A pharmaceutical composition comprising: (a) a liquid carrier comprising water and at least 20% of at least one alcohol; and (b) sildenafil citrate dissolved...
2017/0049775 Methods for Treating Metastatic Pancreatic Cancer Using Combination Therapies Comprising Liposomal Irinotecan...
Combination therapy regimens including liposomal irinotecan, oxaliplatin and 5-fluorouracil are useful in the treatment of pancreatic cancer, including...
2017/0049774 SUSTAINED RELEASE ORAL PHARMACEUTICAL COMPOSITIONS OF TOFACITINIB
The present invention relates to sustained release oral pharmaceutical compositions of tofacitinib comprising tofacitinib, a release controlling polymer, and...
2017/0049773 PHARMACEUTICAL COMPOSITION CONTAINING GPR119 LIGAND AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING...
The present invention relates to a pharmaceutical composition containing a G protein coupled receptor 119 (GPR119) ligand as an active ingredient for...
2017/0049772 INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA
Methods of inhibiting phosphotidylinositol 3-kinase delta isoform (PI3K.delta.) activity, and methods of treating disease, such as disorders of immunity and...
2017/0049771 TARGETING PARP1 FOR TREATMENT OF TSC AND CANCERS
The present invention relates to methods of treating a condition associated with mTORC1 hyperactivation or TSC2-deficient cancer, the method comprising...
2017/0049770 PRODUCT AND METHOD FOR TREATING DIARRHEA
A method of treating diarrhea in a patient includes administering an H1 receptor antagonist and an H2 receptor antagonist to the patient.
2017/0049769 Abuse Deterrent Compositions and Methods of Making Same
This invention relates a therapeutic pharmaceutical composition comprising: a mixture including an opioid; polyethylene oxide in an amount of about 3 to about...
2017/0049768 METHODS FOR TREATING PANCREATIC CANCER USING COMBINATION THERAPIES
Provided are methods for treating pancreatic cancer in a patient by administering liposomal irinotecan (MM-398) alone or in combination with additional...
2017/0049767 COMBINATION THERAPY FOR CANCER TREATMENT
Combination therapies for treating cancer comprising administration of a topoisomerase-1 inhibitor and a PARP inhibitor are provided. The topoisomerase-1...
2017/0049766 METHOD AND DOSE FOR THE ADMINISTRATION OF DEXMEDETOMIDINE, FENTANYL AND PROPOFOL FOR CONSCIOUS SEDATION IN SURGERY
The invention refers to a method and doses in the administration of drugs for conscious sedation of a patient to be used in surgeries, including spinal column...
2017/0049765 Methylphenidate-Prodrugs, Processes of Making and Using the Same
The present technology is directed to prodrugs and compositions for the treatment of various diseases and/or disorders comprising methylphenidate, or...
2017/0049764 Dosing Preparation of Dabigatran Etexilate or a Salt Thereof and a Preparation Method Thereof
Disclosed is an oral dosing preparation of dabigatran etexilate or pharmaceutically acceptable salts thereof and a preparation method thereof.
2017/0049763 NOVEL OXAZOLIDINONE DERIVATIVES
The present invention relates to novel derivatives of oxazolidinone, a method thereof and pharmaceutical compositions comprising the derivatives for use in an...
2017/0049762 5-DEUTERO-2,4-THIAZOLIDINEDIONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME
The invention provides 5-deuterium-enriched 2,4-thiazolidinediones (e.g., 5-[4-[2-(5-ethyl-2-pyridyl)-2-oxoethoxy]benzyl]-5-deutero-thiazolidine-2,- 4-dione),...
2017/0049761 COMPOSITIONS AND METHODS FOR THE TREATMENT OF JUVENILE NEURONAL CEROID LIPOFUSCINOSIS AND RELATED DISORDERS
Provided are materials and methods for the prevention and treatment of Juvenile Neuronal Ceroid Lipofuscinosis comprising administration of an effective amount...
2017/0049760 INHIBITORS OF RHO ASSOCIATED PROTEIN KINASES (ROCK) AND METHODS OF USE
Compounds and compositions having activity as inhibitors of Rho-associated proteinkinases (ROCKs), and methods of making and using the subject compounds are...
2017/0049759 TRANSDERMAL AND/OR TOPICAL DELIVERY SYSTEMS COMPOSED OF DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE IN...
Pharmaceutical compositions for simultaneous transdermal delivery of Doxylamine and Pyridoxine comprising Doxylamine or its salts, Pyridoxine or its salts or...
2017/0049758 LIQUID FORMULATIONS CONTAINING PICOSULFATE AND MAGNESIUM CITRATE
Liquid formulations containing picosulfate and magnesium citrate are provided. The formulations are useful to treat constipation or for the clearance of the...
2017/0049757 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF SYMPTOMS OF ANXIETY AND PANIC USING BETA...
The present invention is focused primarily toward pro re nata ("as needed") treatments for a psychiatric condition or disorder or the symptoms thereof,...
2017/0049756 COMBINATIONS COMPRISING ANTIMUSCARINIC AGENTS AND PDE4 INHIBITORS
Combinations comprising (a) a PDE4 Inhibitor and (b) an antagonist of M3 muscarinic receptors which is ...
2017/0049755 HISTONE DEACETYLASE AS A MODULATOR OF PDL1 EXPRESSION AND ACTIVITY
Disclosed herein is a method for modulating Program Death Receptor Ligand 1 (PDL1) in a cancer cell, comprising contacting the cell with a composition...
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