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Patent # Description
2017/0072046 NOVEL IMMUNOGENIC COMPOSITION
Recombinant chimeric viruses based on NDV LaSota strain and containing either ILTV gB or gD are produced. Administration of the chimeric viruses to chickens...
2017/0072045 INFLUENZA HEMAGGLUTININ PROTEINS AND METHODS OF USE THEREOF
In some embodiments the present invention provides influenza hemagglutinin ("HA") polypeptides, proteins, and protein complexes that comprise a stalk domain...
2017/0072044 TOLL-LIKE RECEPTOR 2 AGONISTS AND VACCINES AND USES THEREOF
The present invention relates to Toll-Like Receptor 2 (TLR2) agonists, in particular, to TLR2-activating lipoproteins, and more particularly to TLR2-activating...
2017/0072043 Multivalent VLP Conjugates
The invention is directed to vaccines comprising capsular polysaccharides conjugated to one or more components of virus like particles (VLP), and methods for...
2017/0072042 SALMONELLA CHOLERAESUIS-SALMONELLA TYPHIMURIUM VACCINES
The present invention relates methods of reducing fecal shedding of animals infected with Salmonella by use of a vaccine or immunogenic composition of...
2017/0072041 EHRLICHIAL INVASIN FOR IMMUNIZTION, DIAGNOSIS, AND CELL DELIVERY
Disclosed are vaccines containing one or more immunogenic polypeptides derived from an EtpE protein from an Ehrlichia sp. or nucleic acid encoding these...
2017/0072040 Mesothelin Vaccines and Model Systems
Mesothelin can be used as an immunotherapeutic target. It induces a cytolytic T cell response. Portions of mesothelin which induce such responses are...
2017/0072039 Malaria Vaccines Based on Pre-Erythrocytic Antigens From P. Falciparum
The present invention relates to polypeptides or fragments thereof for use as malaria vaccines. It also relates to nucleic acid molecules coding for the...
2017/0072038 COMBINATION THERAPY WITH WT1 PEPTIDE VACCINE AND TEMOZOLOMIDE
The present invention relates to combination therapy for cancer with a WT1 peptide vaccine and temozolomide.
2017/0072037 Xenoantigen-Displaying Anti-Cancer Vaccines and Method of Making
Compositions, methods of making, and methods of using, xenoantigen-displaying anti-cancer vaccines are described.
2017/0072036 ANTIGEN SPECIFIC MULTI EPITOPE VACCINES
The presently described subject matter relates to cancer vaccines composed of the signal peptide domain of tumor associated antigens or proteins. The described...
2017/0072035 TUMOR VACCINATION INVOLVING A HUMORAL IMMUNE RESPONSE AGAINST SELF-PROTEINS
The present invention relates to tumor immunotherapy, in particular to tumor vaccination, using chimeric proteins comprising all or a portion of a hepatitis B...
2017/0072034 THERAPEUTIC CANCER VACCINE TARGETED TO HAAH (ASPARTYL-[ASPARAGINYL]-BETA-HYDROXYLASE)
The present invention encompasses a cancer vaccine therapy targeting Aspartyl-[Asparaginyl]-beta.-hydroxylase (HAAH). The present invention contemplates...
2017/0072033 LIPOSOMAL COMPOSITIONS FOR MUCOSAL DELIVERY
A liposomal composition comprising lipids which form a liposomal lipid bilayer, with phospholipid-PEG conjugates incorporated into the liposomal lipid...
2017/0072032 PRENATAL THERAPY TO INDUCE IMMUNE TOLERANCE
Constructs and methods for inducing immune tolerance during gestation, e.g. in utero, are provided. The constructs comprise a moiety that targets and binds to...
2017/0072013 RETRO-INVERSO ANALOGS OF SPADIN DISPLAY INCREASED ANTIDEPRESSANT EFFECTS
Compositions, pharmaceutical compositions and biodegradable pharmaceutical compositions containing at least one analog of spadin or at least one analog of a...
2017/0072008 AUTOASSEMBLING PEPTIDES FOR THE TREATMENT OF PULMONARY BULLA
Materials and methods for treatment of pulmonary bulla are provided. A peptide comprising between about 7 amino acids and about 32 amino acids in a solution...
2017/0071993 COMPOSITION OF MANGIFERA INDICA AND METHOD OF MAKING AND USING THEREOF
The invention relates to a herbal composition derived from Mangifera indica. Methods of making and using the composition for the management of obesity are also...
2017/0071964 METHODS FOR TREATING ARENAVIRIDAE AND CORONAVIRIDAE VIRUS INFECTIONS
Provided are methods for treating Arenaviridae and Coronaviridae virus infections by administering nucleosides and prodrugs thereof, of Formula I: ...
2017/0071938 STABLE AND SOLUBLE FORMULATIONS OF RECEPTOR TYROSINE KINASE INHIBITORS, AND METHODS OF PREPARATION THEREOF
The present disclosure relates to stable formulations of receptor tyrosine kinase inhibitors (TKI), e.g., pazopanib; methods of preparation thereof; and use of...
2017/0071924 METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS
A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a...
2017/0071922 ARTIFICIAL SKIN
The present invention relates to a method for producing artificial skin, comprising: adding a matrix metalloproteinase inhibitor and a heparanase inhibitor to...
2017/0071913 NOVEL SOLID FORMS OF BENDAMUSTINE HYDROCHLORIDE
Novel solid forms of bendamustine hydrochloride are described, as well as methods of their preparation and use.
2017/0071909 NOVEL GAMMA-AMINOBUTYRIC ACID (GABA) ANALOGUES FOR THE TREATMENT OF PAIN AND OTHER DISORDERS
A compound of Formula 1 ##STR00001## wherein R.sub.1 represents hydrogen, halo, a C1-C4 alkyl group, a C1-C4 alkylhalide group, a C1-C4 alkoxy-C2-C4 alkyl group,...
2017/0071908 PYRROLIDINE- SUBSTITUTED FLAVONE DERIVATIVES FOR PREVENTION OR TREATMENT OF ORAL MUCOSITIS
The present invention relates to the pyrrolidine substituted with flavone derivatives, represented by the compounds of Formula (I) (as described herein) or...
2017/0071901 METHODS AND FORMULATIONS FOR INCREASING CHEMICAL STABILITY AND BIOLOGICAL ACTIVITY OF PHENOLIC COMPOUNDS
The present teachings show that co-addition of a series of redox active antioxidants with diverse chemical structures dramatically increases the chemical...
2017/0071898 ULTRAPURE TETRAHYDROCANNABINOL-11-OIC ACIDS
This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use...
2017/0071891 FUMARATE ESTER PHARMACEUTICAL COMPOSITIONS
Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In...
2017/0071888 GABA ANALOG PRODRUG SUSTAINED RELEASE ORAL DOSAGE FORMS
Sustained release oral dosage forms of a gabapentin prodrug, 1-{[(.alpha.-isobutanoyloxyethoxy)carbonyl]aminomethyl}-1-cyclohexane acetic acid, are disclosed....
2017/0071883 Systems and Methods for Increasing Agmatine Cellular Uptake by Oral Administration
Formulations of hydrosoluble stable organic salts including, but not limited to, agmatine orotate, agmatine di-hydrochloride, agmatine phosphate, buffered...
2017/0071882 DAPSONE TO TREAT ROSACEA
The methods described herein provide treatment of rosacea using topical formulations of dapsone. The methods also provide treatment of rosacea with topical...
2017/0071881 EPINEPHRINE NANOPARTICLES, METHODS OF FABRICATION THEREOF, AND METHODS FOR USE THEREOF FOR TREATMENT OF...
The invention provides a composition including epinephrine nanoparticles and methods for therapeutic use of the composition in the treatment of conditions...
2017/0071880 SELEGILINE TRANSDERMAL SYSTEM
Embodiments of the invention relate generally to the field of transdermal delivery and more specifically to transdermal patches containing selegiline base for...
2017/0071879 PROTOTYPICAL ANALGESIC PROFILE OF 3,3-DIPHENYL-N-(1-PHENYLETHYL)PROPAN-1-AMINE (FENDILINE)
The present invention discloses the prototypical profile of 3,3-diphenyl-N-(1-phenylethyl) propan-1-amine (fendiline) against the anticancer drugs induced...
2017/0071878 NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS
The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for use, and...
2017/0071877 PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT CONTAINING GOSSYPOL AND PHENFORMIN AS ACTIVE INGREDIENTS
The present invention relates to a pharmaceutical composition for cancer treatment containing gossypol and phenformin as active ingredients. Specifically, the...
2017/0071876 CYANIDE ANTIDOTE COMPOSITIONS AND METHODS OF USE
Cyanide antidote compositions and methods of use are described herein. A cyanide antidote composition may include a sulfur analog, sulfur analog derivative, or...
2017/0071875 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF DRY EYE
The invention relates to therapeutic compositions for the treatment of dry eye, more specifically to compositions comprising a TRPM8 receptor agonist ligand....
2017/0071874 TOPICAL ANALGESIC
One or more of embodiments of the present invention generally concern a topical analgesic, which can be used to treat painful skin ailments. The topical...
2017/0071873 COMPOSITION OF NANOFORMULATED LYCOPENE AND METHOD OF USING THE COMPOSITION
A nano-composition and a method of using the composition. The composition includes nanoparticles. Each nanoparticle includes a shell encapsulating lycopene....
2017/0071872 FENTANYL-CONTAINING PATCH FOR EXTERNAL USE
A patch for external use which has a laminate structure comprising a substrate and a pressure-sensitive adhesive layer which contains a ...
2017/0071871 UNIFORM FILMS FOR RAPID DISSOLVE DOSAGE FORM INCORPORATING TASTE-MASKING COMPOSITIONS
The present invention relates to rapid dissolve thin film drug delivery compositions for the oral administration of active components. The active components...
2017/0071870 Transdermal Delivery of Cannabidiol with Other Active Moieties Including Cannabinoids
Transdermal delivery devices for the delivery of cannabidiol (CBD) and related moieties are shown and described. In a reservoir-patch design, a microporous,...
2017/0071869 TRANSMUCOSAL DELIVERY OF LAQUINIMOD BY ORAL PATCHES
The subject invention provides an oral patch comprising: a) a liner; and b) a film composition thereon, the film composition comprising (i) laquinimod in an...
2017/0071868 PoP NANOCOMPOSITE STRUCTURES AND METHODS OF TRANSFERRING DRUGS USING THE SAME
A PoP nano-composite structure includes a first nano-particle containing a drug therein, and second nano-particles that surround a surface of the first...
2017/0071867 NOVEL NANOPARTICLE COMPOSITIONS
The present invention provides, among other things, nanoparticle compositions including a plurality of nanoparticles, each of which is comprised of a...
2017/0071866 NANOPARTICLES LOADED WITH ACTIVE INGREDIENTS, THEIR PROCESS OF PREPARATION, AND THEIR USES
The present disclosure concerns nanoparticles loaded with active ingredients with controlled average diameter, their processes of preparation, their...
2017/0071865 ACTIVE AGENT-CONTAINING MICROCAPSULES
Multi-layer microcapsules comprising a core comprising one or more active agents and two or more shells comprised of a wall-forming polymeric material, an...
2017/0071864 Compositions for Treatment of Attention Deficit Hyperactivity Disorder
Therapeutic compositions deliver a therapeutic amount of methylphenidate in a delayed and extended release formulation. The dosage form exhibits a lag time...
2017/0071863 ORAL PHARMACEUTICAL DOSAGE FORMS OF BUDESONIDE
The present invention relates to novel oral sustained release pharmaceutical dosage forms for delivery of budesonide to the lower gastrointestinal tract for...
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