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Patent # Description
2017/0096705 MICROFLUIDIC DEVICES, SYSTEMS AND METHODS FOR SAMPLE PREPARATION AND ANALYSIS
The present disclosure provides microfluidic devices, systems and methods for sample preparation and/or analysis. A microfluidic device can include a first...
2017/0096704 DNA SEQUENCING BY NANOPORE USING MODIFIED NUCLEOTIDES
This invention provides a process for sequencing single-stranded DNA or RNA by employing a nanopore and modified nucleotides.
2017/0096703 ANALYSIS OF A POLYMER FROM MULTI-DIMENSIONAL MEASUREMENTS
A target sequence of polymer units is estimated from plural series of measurements taken from sequences of polymer units that comprise the target sequence or a...
2017/0096702 Isothermal Nucleic Acid Amplification Reactor With Integrated Solid State Membrane
Provided are devices adapted to isolate, amplify, and detect nucleic acids that may be present in a biological sample. The devices can, in some embodiments,...
2017/0096701 LABELED CIRCULAR DNA MOLECULES FOR ANALYSIS OF DNA TOPOLOGY, AND TOPOISOMERASES AND FOR DRUG SCREENING
The present invention provides labeled circular plasmid DNA molecules for studying DNA topology and topoisomerases. The molecules of the present invention also...
2017/0096700 NOVEL PCR PRIMERS AND METHODS THEREOF FOR THE IDENTIFICATION OF BACILLUS COAGULANS
The present invention discloses novel oligonucleotide primer sequences BC1, BC2 and BC3 for the identification of Bacillus coagulans. The invention also...
2017/0096699 METHOD FOR EVALUATING SUITABILITY OF DUODENAL FLUID SAMPLE AS SAMPLE FOR DETECTING PANCREATIC FLUID-DERIVED...
A method is provided for evaluating the suitability of a duodenal fluid sample collected from an animal as a sample for detecting pancreatic fluid-derived...
2017/0096698 SUMOylation Assay and Related Reagents
Provided herein and methods and kits for identifying inhibitors of SUMOylation. The provided methods include contacting a candidate agent with (i) a...
2017/0096697 REAGENT CARTRIDGE FOR DETECTION OF CELLS
An apparatus includes a housing and an actuator. The housing, which defines a reagent volume that can receive a reagent container, can be removably coupled to...
2017/0096696 Hybrid Suppressor tRNA for Vertebrate Cells
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in vertebrate...
2017/0096695 Methods of Producing Rhamnolipids
The present invention relates to a method of preparing at least one rhamnolipid comprising: contacting a recombinant cell with a medium containing a carbon...
2017/0096694 STRAND-INVASION BASED DNA AMPLIFICATION METHOD
Methods for amplification of a target nucleic acid sequence comprising strand invasion are provided in which strand invasion occurs both at upstream and...
2017/0096693 Methods for Production of Xylosylxylitol Oligomers
The present disclosure relates generally to the production of xylosyl-xylitol oligomers, and more specifically to biological methods for producing...
2017/0096692 CELL-FREE PREPARATION OF CARBAPENEMS
Provided herein are cell-free systems for generating carbapenems, e.g., a compound of the Formula (I): ##STR00001## or salts thereof; wherein , R.sup.1, R.sup.2,...
2017/0096691 SELECTIVE ADVANTAGE IN FERMENTATION
Disclosed are transformed cells and related nucleotide and protein sequences, and fermentation compositions and methods, all of which are related to providing...
2017/0096690 Means and Methods for Itaconic Acid Production
The present invention relates to a method of producing itaconic acid. Further the present invention relates to nucleic acids encoding an ...
2017/0096689 SEMI-SYNTHETIC TEREPHTHALIC ACID VIA MICROORGANISMS THAT PRODUCE MUCONIC ACID
The invention provides a non-naturally occurring microbial organism having a muconate pathway having at least one exogenous nucleic acid encoding a muconate...
2017/0096688 METHODS AND COMPOSITIONS FOR ENHANCED PRODUCTION OF FATTY ALDEHYDES AND FATTY ALCOHOLS
The invention relates to the use of EntD polypeptides, polynucleotides encoding the same, and homologues thereof to enhance the production of fatty aldehydes...
2017/0096687 XYLANASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
The present invention relates to xylanase variants, comprising an alteration at least at one position corresponding to position 87 of the polypeptide of SEQ ID...
2017/0096686 TRANSGENIC TOBACCO PLANTS FOR ENHANCED BIOETHANOL PRODUCTION
Genetically modified tobacco plants are provided having altered hexose accumulation. Methods are provided for producing ethanol from fermentation of tobacco...
2017/0096685 Microorganisms for Biosynthesis of Limonene on Gaseous Substrates
Engineered microorganisms are provided that convert gaseous substrates, such as producer gas, into limonene. In some embodiments, limonene is pumped out of the...
2017/0096684 LENTIVIRAL VECTORS
This invention relates to lentiviral gene transfer vectors pseudotyped with hemagglutinin-neuraminidase (HN) and fusion (F) proteins from a respiratory...
2017/0096683 AAV VECTORS FOR RETINAL AND CNS GENE THERAPY
Provided herein are improved rAAV (e.g., rAAV2, rAAVrh8R, etc.) for enhanced gene therapy of ocular disorders or CNS disorders wherein the rAAV comprise one or...
2017/0096682 AAV VECTORS FOR VASCULAR GENE THERAPY IN CORONARY HEART DISEASE AND PERIPHERAL ISCHAEMIA
The invention relates to the provision of a gene therapy for coronary heart disease and peripheral ischemia in mammals. One embodiment is an adeno-associated...
2017/0096681 ENHANCED EXPRESSION AND STABILITY REGIONS
Expression-enhancing nucleotide sequences for expression in eukaryotic systems are provided that allow for enhanced and stable expression of recombinant...
2017/0096680 BIOLOGICAL STATE MACHINES
Provided herein are recombinase-based frameworks for building state machines in vitro and in vivo by using chemically controlled DNA excision and inversion...
2017/0096679 EUKARYOTIC EXPRESSION VECTORS RESISTANT TO TRANSGENE SILENCING
The present invention relates to recombinant DNA molecules such as plasmids, non-viral vectors, viral vectors and hybrids thereof, and more particularly to...
2017/0096678 METHOD FOR INCREASING THE RESISTANCE OF A PLANT TO A PLANT RNA VIRUS
The disclosure relates to a method for increasing the resistance of a plant to a plant RNA virus, comprising expressing in said plant a mutant protein-only...
2017/0096677 GENETICALLY MODIFIED PLANTS FOR CROP YIELD ENHANCEMENT
This invention is related to methods for producing a plant having improved/enhanced crop yield as compared to a corresponding wild type plant, such method...
2017/0096676 Expression of Butyrylcholinesterase in plants
Method and plants expressing increased levels of Butyrylcholinesterase (BChE) is described. The nucleic acid molecule encoding BChE is operably linked to a...
2017/0096675 HIBISCUS CANNABINUS FERULOYL-COA:MONOLIGNOL TRANSFERASE
The invention relates to isolated nucleic acids encoding a feruloyl-CoA:monolignol transferase and feruloyl-CoA:monolignol transferase enzymes. The isolated...
2017/0096673 Chimeric Retinoid X Receptors and Their Use in a Novel Ecdysone Receptor-Based Inducible Gene Expression System
This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More...
2017/0096672 Novel Ecdysone Receptor/Invertebrate Retinoid X Receptor-Based Inducible Gene Expression System
This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More...
2017/0096671 MICRORNA INDUCTION OF CARDIAC REGENERATION
The invention relates to compostions and methods for promoting cellular proliferation and de-differentiation of cells into stem cells to foster tissue...
2017/0096670 DNA APTAMERS SPECIFIC TO CD200R1 AND THEIR THERAPEUTIC USES
Disclosed are short DNA aptamers that selectively recognize CD200R1, a protein expressed on the surface of myeloid and lymphoid cells that delivers immune...
2017/0096669 DIAGNOSIS AND TREATMENT OF FRIEDREICH'S ATAXIA
The present invention is directed to oligonucleotides based on peptide nucleic acid oligonucleotide or an equivalent oligonucleotide analogue, such as...
2017/0096668 COMPOUNDS AND METHODS FOR ENHANCED CELLULAR UPTAKE
Described herein are conjugated modified oligonucleotides that are complementary to a target RNA. The conjugate facilitates cellular uptake of the modified...
2017/0096667 INHIBITING GENE EXPRESSION WITH dsRNA
The present invention relates to the specific inhibition of gene expression in mammals by bringing the target gene into contact with double stranded RNA (dsRNA).
2017/0096666 METHOD OF THERAPY AND DIAGNOSIS OF ENDOTHELIAL DYSFUNCTION
The invention discloses a method of therapy of endothelial dysfunction, by administering microRNA let-7g to a subject in need, wherein the microRNA let-7g...
2017/0096665 Compositions and Methods for Inhibiting Gene Expression of LPA
RNA interference (RNAi) agents and RNAi agent conjugates for inhibiting the expression of the LPA (apo(a)) gene are described. Pharmaceutical compositions...
2017/0096664 SPINAL MUSCULAR ATROPHY (SMA) TREATMENT VIA TARGETING OF SMN2 SPLICE SITE INHIBITORY SEQUENCES
The present invention is directed to methods and compositions capable of blocking the inhibitory effect of a newly-identified intronic inhibitory sequence...
2017/0096663 siRNA Therapy for Transthyretin (TTR) Related Ocular Amyloidosis
The invention relates to a method of treating ocular amyloidosis by reducing TTR expression in a subject by administering a double-stranded ribonucleic acid...
2017/0096662 ADMINISTERING ANTISENSE OLIGONUCLEOTIDES COMPLEMENTARY TO HUMAN APOLIPOPROTEIN B
Methods for long-term lowering of lipid levels in human subjects and for the treatment of conditions associated with elevated LDL-cholesterol and elevated ApoB...
2017/0096661 CONCENTRATING NUCLEIC ACIDS IN URINE
Provided is a method for concentrating nucleic acids in urine which can be performed without use of toxic reagents and without centrifugation steps. The method...
2017/0096660 FABRICATION OF HIERARCHICAL SILICA NANOMEMBRANES AND USES THEREOF FOR SOLID PHASE EXTRACTION OF NUCLEIC ACIDS
The present invention provides a novel method to fabricate silica nanostructures on thin polymer films based on silica deposition and self-wrinkling induced by...
2017/0096659 METHODS AND DEVICES FOR SIMULTANEOUS OPTICAL IRRADIATION AND OSCILLATING MAGNETIC FIELD RADIATION OF A TARGET
The present disclosure is generally directed to methods and devices for the precise and simultaneous optical irradiation and oscillating magnetic field...
2017/0096658 MESOPOROUS CATALYSTS OF MAGNETIC NANOPARTICLES AND FREE-RADICALPRODUCING ENZYMES, AND METHODS OF USE
A composition comprising mesoporous aggregates of magnetic nanoparticles and free-radical producing enzyme (i.e., enzyme-bound mesoporous aggregates), wherein...
2017/0096657 PROCESSES FOR PREPARING SILICA-CARBON ALLOTROPE COMPOSITE MATERIALS AND USING SAME
The present document describes a carbon allotrope-silica composite material comprising a silica microcapsule comprising a silica shell having a thickness of...
2017/0096656 THERMOSTABLE ALGINATE DEGRADING ENZYMES AND THEIR METHODS OF USE
The present invention relates to the identification, production and use of thermostable alginate lyase enzymes that can be used to partially degrade alginate...
2017/0096655 COAGULATION FACTOR VII POLYPEPTIDES
The present invention relates to modified coagulation Factor VII polypeptides exhibiting increased resistance to antithrombin inactivation and enhanced...
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