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Patent # Description
2017/0101673 METHODS AND COMPOSITIONS FOR THE QUANTITATION OF MITOCHONDRIAL NUCLEIC ACID
Provided herein are products and processes for the quantitation of mitochondrial nucleic acid in a sample from a subject. In certain aspects are multiplex...
2017/0101672 IN SITU DETECTION OF NUCLEOTIDE VARIANTS IN HIGH NOISE SAMPLES, AND COMPOSITIONS AND METHODS RELATED THERETO
The invention relates to methods of in situ detection of a nucleic acid variation of a target nucleic acid in a sample, including single nucleotide variations,...
2017/0101671 Ligation Assays in Liquid Phase
Ligation assays in liquid phase for detecting nucleic acid sequences.
2017/0101670 METHOD FOR DETECTING RARE MUTATION
Disclosed is a method for detecting a rare mutation. The method comprises: preparing a sample comprising not more than 1,000 copies of template DNA; amplifying...
2017/0101669 Nucleic Acid Based Sensor and Methods Thereof
The present disclosure relates to a nucleic acid based sensor, comprising a sensing 5 module, a normalizing module and a targeting module. It also relates to a...
2017/0101668 SYSTEMS AND METHODS FOR SUBSTRATE ENRICHMENT
A method of separating bead substrates includes applying an emulsion to an emulsion-breaking solution. A dispersed phase of the emulsion includes an unbound...
2017/0101667 Apparatus and Methods for Parallel Processing of Microvolume Liquid Reactions
Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one...
2017/0101666 METHODS AND SYSTEMS FOR MULTIPLEX QUANTITATIVE NUCLEIC ACID AMPLIFICATION
The present disclosure provides methods, devices and systems that enable simultaneous multiplexing amplification reaction and real-time detection in a single...
2017/0101665 Nucleic Acid Amplification With Integrated Multiplex Detection
Compositions and methods of detecting multiple proteins of interest in a sample using arrays are provided herein.
2017/0101664 Degradation Resistant Peptide Based Biosensors
Disclosed are compositions and methods for measuring tyrosine kinase activity using degradation resistant biosensors comprising a reporter sequence, a target...
2017/0101663 METHODS FOR DISTINGUISHING AND IDENTIFYING PLANT VARIETIES
Methods are disclosed for distinguishing and identifying plants by measuring partial hydrolysis of polysaccharides on account of polysaccharide-hydrolyzing...
2017/0101662 SYSTEM AND METHOD FOR DETECTING NEURAL INJURY
A detection system for determining pyruvate dehydrogenase (PDH) levels in a bodily sample includes at least one reaction solution for generating NAD.sup.+ upon...
2017/0101661 BIOSENSOR
It is an object of the present invention to provide a sensor, which is capable of measuring, quickly and in high accuracy, concentration of neutral fat from a...
2017/0101660 ENZYME-IMMOBILIZED POROUS MEMBRANE AND PREPARATION METHOD OF ANTIBIOTICS USING THE SAME
The present disclosure relates to an enzyme-immobilized porous membrane and a preparation method of antibiotics using the same, and more specifically, to an...
2017/0101659 METHODS FOR INCREASING MOLECULAR DIVERSITY OF POLYKETIDES AND NON-RIBOSOMAL PROTEINS
A method for increasing the molecular diversity of polyketides and non-ribsomomal peptides by using recombination to efficiently increase or decrease the...
2017/0101658 METHODS AND COMPOSITIONS FOR EXPRESSION OF POLYPEPTIDES IN A CELL
Disclosed herein are vector systems for expression of polypeptides in eukaryotic cells; and methods of obtaining high-level expression of polypeptides in a...
2017/0101657 METHODS OF GANGLIOSIDE PRODUCTION
The invention provides methods for production of gangliosides, e.g., GM1, from cells in culture using, for example, bone marrow cells and neuroblastoma cells....
2017/0101656 O-SUCCINYLHOMOSERINE PRODUCING MICROORGANISM AND METHOD FOR PRODUCING O-SUCCINYLHOMOSERINE USING SAME
Provided are a microorganism of the genus Escherichia for producing O-succinylhomoserine and a method for producing O-succinylhomoserine using the same.
2017/0101655 MICROORGANISM PRODUCING O-ACETYL HOMOSERINE AND THE METHOD OF PRODUCING O-ACETYL HOMOSERINE USING THE SAME
Disclosed is a microorganism of Escherichia sp. producing O-acetyl homoserine, and a method of producing O-acetyl homoserine in high yield using the...
2017/0101654 ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE CHIRAL AMINES
The present invention relates to a method of enantioselective enzymatic transamination of (1R)-1-Hydroxy-1-Phenylacetone (R-PAC) to a chiral amine 1R,...
2017/0101653 Activity of Fe-S Cluster Requiring Proteins
The present invention is related to a recombinant host cell, in particular a yeast cell, comprising a dihydroxy-acid dehydratase polypeptide. The invention is...
2017/0101652 HYBRID PROTEINS AND USES THEREOF
There are disclosed hybrid proteins comprising at least one signal sequence; at least one DNA binding domain; and at least one cell penetrating peptide (CPP)...
2017/0101651 WUPA NUCLEIC ACID MOLECULES THAT CONFER RESISTANCE TO COLEOPTERAN AND HEMIPTERAN PESTS
This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran and hemipteran pests through RNA interference-mediated...
2017/0101650 POLYNUCLEOTIDES AND POLYPEPTIDES IN PLANTS
The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of...
2017/0101649 Method of Enhancing Translation of Foreign Genes in Plants
Embodiments of the present invention comprise altering the biosynthesis and accumulation of sucrose in legumes by transforming the plants with the sucrose...
2017/0101648 BIOLOGICAL METHODS FOR PREPARING A FATTY DICARBOXYLIC ACID
The technology relates in part to biological methods for producing a fatty dicarboxylic acid and engineered microorganisms capable of such production.
2017/0101647 DNA VECTORS, TRANSPOSONS AND TRANSPOSASES FOR EUKARYOTIC GENOME MODIFICATION
The present invention provides polynucleotide vectors for high expression of heterologous genes. Some vectors further comprise novel transposons and...
2017/0101646 DNA VECTORS, TRANSPOSONS AND TRANSPOSASES FOR EUKARYOTIC GENOME MODIFICATION
The present invention provides polynucleotide vectors for high expression of heterologous genes. Some vectors further comprise novel transposons and...
2017/0101645 COMPOSITIONS AND METHODS FOR MODULATING DYSFERLIN EXPRESSION
Aspects of the disclosure relate to methods of altering RNA splicing in a subject. In some embodiments, methods are provided for correcting splicing in a cell...
2017/0101644 SMALL INTERFERING RNA (siRNA) FOR THE THERAPY OF TYPE 2 (ADO2) AUTOSOMAL DOMINANT OSTEOPETROSIS CAUSED BY CLCN7...
The present invention lies in the field of molecules known as "small interfering RNA" with therapeutic applications. siRNAs have the ability to reduce gene...
2017/0101643 FUNGAL PROTEASES
The present invention provides fungal proteases and improved fungal strains that are deficient in protease production.
2017/0101642 METHODS OF INHIBITING VIRAL REPLICATION COMPRISING THE SIGNAL PEPTIDASE COMPLEX
The present invention is directed to compositions targeting the signal peptidase complex and methods of use in treating and preventing flavivirus infection.
2017/0101641 MODULATION OF GENE EXPRESSION AND SCREENING FOR DEREGULATED PROTEIN EXPRESSION
Disclosed herein include compositions and methods of modulating protein expression that utilizes an activator or a repressor of a non-sense mediated RNA decay...
2017/0101639 RNAi PHARMACEUTICAL COMPOSITION FOR SUPPRESSING EXPRESSION OFCKAP5 GENE
The present invention provides a composition for suppressing the expression of the CKAP5 gene, the composition comprising a lipid particle containing a...
2017/0101638 ACETYL-COA CARBOXYLASES
The present invention provides various combinations of genetic modifications to a. transformed host cell that provide increase conversion of carbon to a...
2017/0101637 Psicose Epimerase and Psicose Production Method Using Same
The present invention provides a novel psicose epimerase derived from Flavonifractor plautii and capable of converting fructose to psicose. The novel psicose...
2017/0101636 PROTEASE-CLEAVAGE RESISTANT, SHIGA TOXIN A SUBUNIT EFFECTOR POLYPEPTIDES AND CELL-TARGETED MOLECULES COMPRISING...
The present invention provides protease-cleavage resistant molecules comprising Shiga toxin effector polypeptides capable of exhibiting potent, Shiga toxin...
2017/0101635 VARIANTS OF GH FAMILY 11 XYLANASE AND POLYNUCLEOTIDES ENCODING SAME
The present invention relates to GH Family 11 xylanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid...
2017/0101634 EXTRACELLULAR HYALURONIDASE FROM STREPTOMYCES KOGANEIENSIS
A process for preparing Streptomyces koganeiensis ATCC 31394 hyaluronidase includes obtaining hyaluronidase having molecular weight of 21.6 kDalton, which has...
2017/0101633 METHOD OF MAINTAINING DISEASE STABILITY IN A SUBJECT HAVING GAUCHER'S DISEASE
A method of maintaining disease stability in a subject having Gaucher's disease following switch from enzyme replacement therapy (ERT) is provided. The method...
2017/0101632 DNA POLYMERASES WITH IMPROVED ACTIVITY
Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful...
2017/0101631 GENETICALLY ENGINEERED BACTERIUM COMPRISING ENERGY-GENERATING FERMENTATION PATHWAY
The invention relates to a genetically engineered bacterium comprising an energy-generating fermentation pathway and methods related thereto. In particular,...
2017/0101630 DNA VECTORS, TRANSPOSONS AND TRANSPOSASES FOR EUKARYOTIC GENOME MODIFICATION
The present invention provides polynucleotide vectors for high expression of heterologous genes. Some vectors further comprise novel transposons and...
2017/0101629 DNA VECTORS, TRANSPOSONS AND TRANSPOSASES FOR EUKARYOTIC GENOME MODIFICATION
The present invention provides polynucleotide vectors for high expression of heterologous genes. Some vectors further comprise novel transposons and...
2017/0101628 CELL CULTURE SYSTEM
The embodiments of the invention described herein relate to systems and methods for culturing and/or maintaining intestinal cells, tissues and/or organoids in...
2017/0101627 SUPERCENTENARIAN INDUCED PLURIPOTENT STEM (sciPS) CELLS AND METHODS OF MAKING AND USING THEREOF
Provided herein are cells and methods for reprogramming iPS cells from a supercentanarian and their differentiated derivatives having differences from...
2017/0101626 METHODS FOR REPROGRAMMING CELLS AND USES THEREOF
A method of obtaining a cardiac multipotent or unipotent cell, comprising: i) providing a cell of a first type which is not a cardiac multipotent or unipotent...
2017/0101625 MODULATED IMMUNODOMINANCE THERAPY
The invention involves generating a T cell response to subdominant antigens and using the cells to therapeutically change the cellular homeostasis and nature...
2017/0101624 METHODS OF ENHANCING T-CELL LONGEVITY AND USES THEREOF
The present disclosure encompasses methods of enhancing T cell longevity and/or T cell function by promoting mitochondrial fusion and/or mitochondrial...
2017/0101623 METHODS FOR REPROGRAMMING CELLS AND USES THEREOF
An in vitro human neural multipotent, unipotent, or somatic cell possessing all of the following characteristics: is derived from the reprogramming of a...
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