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Patent # Description
2017/0100486 COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES
A novel delivery system for drugs, and especially macromolecules such as proteins or oligonucleotides through biological membranes is provided, and...
2017/0100485 METAL-POLYSACCHARIDE CONJUGATES: METHODS FOR CANCER THERAPY
The current disclosure, in one embodiment, includes a polysaccharide conjugate. This conjugate has a polysaccharide and at least one monomeric amino acid...
2017/0100484 DRUG DELIVERY CARRIER FOR SUSTAINED RELEASE OF MEDICINAL PROTEINS AND METHOD FOR PRODUCTION THEREOF
Disclosed is a drug delivery carrier for sustained release of medicinal protein. The drug delivery carrier has an effect of efficiently loading medicinal...
2017/0100483 COMPOSITIONS OF A POLYORTHOESTER AND AN APROTIC SOLVENT
Delivery systems and compositions comprised of a biodegradable polyorthoester polymer, an aprotic solvent, and a drug are described. The solvent is selected to...
2017/0100482 LIPOCATIONIC POLYMERS AND USES THEREOF
Polymers produced by ring opening polymerization which comprises an amino group that can be used in compositions to deliver a nucleic acid such as a miRNA or a...
2017/0100481 TRANSDERMAL PHARMACEUTICAL COMPOSITIONS WITH REDUCED SKIN IRRITATION
Described are transdermal pharmaceutical compositions exhibiting reduced skin irritation potential comprising a steroid and an antioxidant, useful for reducing...
2017/0100480 CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND USES THEREOF
The current invention provides a controlled release oral solid formulation of levodopa comprising levodopa, a decarboxylase inhibitor, and a carboxylic acid....
2017/0100479 Activation Of Immune-Related Signaling Pathways In Cells Via Optofection
Systems and methods of inducing large-scale optical transfection and generation of an immune response in target cells are presented. In preferred aspects...
2017/0100478 ANTI-ANGIOGENESIS THERAPY FOR THE TREATMENT OF BREAST CANCER
This invention concerns in general treatment of diseases and pathological conditions with anti-VEGF antibodies. More specifically, the invention concerns the...
2017/0100477 Methods of Immunizing a Subject and Compositions Related Thereto
This disclosure relates to methods of immunization comprising administering an effective amount of an immunogenic composition comprising an antigen or vaccine...
2017/0100476 HSP-FREE ALLERGEN PREPARATION
A pharmaceutical preparation comprising--10 to 200 .mu.g/ml of fragments of an antigenic structure which induces allergic reaction--2 to 6% (w/v) mannitol--0.5...
2017/0100475 INDUCTION OF MUCOSAL TOLERANCE TO ANTIGENS
The present invention relates to the induction of tolerance to antigens, by mucosal, preferably oral delivery of the antigen in combination with an...
2017/0100474 METHODS AND COMPOSITIONS FOR LIVE ATTENUATED VIRUSES
Embodiments herein relate to compositions of and methods for live viruses. In certain embodiments, a live, attenuated virus composition includes, but is not...
2017/0100473 VACCINE FOR INTRAUTERINE DISEASE
Provided are compositions and methods for use in prophylaxis of puerperal metritis and improving reproductive function of ruminants. The methods and...
2017/0100472 COMBINATION VACCINES WITH SEROGROUP B MENINGOCOCCUS AND D/T/P
Serogroup B meningococcus antigens can successfully be combined with diphtheria, tetanus and pertussis toxoids ("DTP") to provide effective combination...
2017/0100471 MENINGOCOCCAL MULTIVALENT NATIVE OUTER MEMBRANE VESICLE VACCINE, METHODS OF MAKING AND USE THEREOF
The present technology provides vaccine compositions comprising native outer membrane vesicles (NOMVs) from at least one genetically modified strain of...
2017/0100470 PROTEINS AND NUCLEIC ACIDS USEFUL IN VACCINES TARGETING STAPHYLOCOCCUS AUREUS
Disclosed are novel immunogenic proteins derived from Staphylococcus aureus, as well as methods for their use in conferring protective immunity against S....
2017/0100469 COMPOSITIONS AND METHODS COMPRISING KLK3 OR FOLH1 ANTIGEN
The present invention provides KLK3 peptides, FOLH1 peptides, recombinant polypeptides comprising same, recombinant nucleotide molecules encoding same,...
2017/0100468 AMPLIFICATION OF EPITOPE SPECIFIC PERSONALIZED ANTI-ANGIOGENIC IMMUNE RESPONSES
Disclosed are therapeutic means, protocols, and compositions of matter useful for treatment of cancer by eliciting and amplifying immune responses specific to...
2017/0100467 PCSK9 VACCINE
The present invention relates to the provision of novel immunogens comprising an antigenic PCSK9 peptide linked to an immunogenic carrier for the prevention,...
2017/0100466 STRATEGIES TO PREVENT AND/OR TREAT IMMUNE RESPONSES TO SOLUBLE ALLOFACTORS
The present invention relates to the use of immunogenic peptides comprising a T-cell epitope derived from a soluble allofactor and a redox motif such as...
2017/0100464 DENTAL GEL COMPOSITION OF PAPAIN FOR THE ATRAUMATIC TREATMENT OF CARIES AND METHOD OF PREPARING SAME
A papain dental gel composition is disclosed for the atraumatic treatment of caries which comprises papain with a final activity of at least 3,000 U/mg,...
2017/0100463 METHOD TO IMPROVE SAFETY AND EFFICACY OF ANTI-CANCER THERAPY
The invention relates to the use of a deoxyribonuclease (DNase) enzyme for prevention or amelioration of toxicity associated with various cytostatic and/or...
2017/0100462 GENOMIC INSTABILITY MARKERS IN FANCONI ANEMIA
Markers for genomic instability in Fanconi Anemia (FA) and other pathologies for therapeutic and diagnostic uses. In one embodiment, glycosphingolipid...
2017/0100461 CONTROLLED RELEASE FORMULATIONS OF OCTREOTIDE
A formulation of octreotide or pharmaceutically acceptable salts thereof, which provides controlled release of a therapeutically effective amount of octreotide...
2017/0100460 USE OF SERELAXIN TO REDUCE GDF-15
Growth differentiation factor 15 (GDF-15) is a stress-responsive cytokine known to be associated with adverse events in heart failure patients. The use of...
2017/0100459 THERAPEUTIC AGENT PREPARATIONS FOR DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG...
Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many...
2017/0100458 USE OF CPNE7 FOR DIFFERENTIATING NON-DENTAL MESENCHYMAL STEM CELLS INTO ODONTOBLASTS, REGENERATING DENTAL PULP...
The present invention relates to: composition for differentiating non-dental mesenchymal stem cells into odontoblasts comprising CPNE7 protein or gene; method...
2017/0100457 IMMEDIATE-RELEASE TABLET FORMULATION, COMPOSITION FOR TABLETS AND METHOD FOR MANUFACTURING IMMEDIATE-RELEASE...
There are provided a tablet-form immediate-release preparation that contains a high concentration of a casein and/or a casein hydrolysate as an active...
2017/0100456 METHODS AND COMPOSITIONS FOR IMMUNOMODULATION
The methods and uses described herein relate to the modulation of the immune system by modulation of Sema3F levels and/or activity, e.g. suppressing allograft...
2017/0100455 USING HEAT SHOCK PROTEINS TO IMPROVE THE THERAPEUTIC BENEFIT OF A NON-VACCINE TREATMENT MODALITY
The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an ...
2017/0100454 COMPOSITIONS AND METHODS FOR TARGETING NUCLEAR IMPORT SHUTTLES AND TREATING INFLAMMATORY DISORDERS
The present invention relates to compositions and methods for treating autoimmune, microbial, metabolic, neoplastic, and posttraumatic diseases mediated by...
2017/0100453 Chemical Induction of Lactation in Prepubescent Non-Human Mammals
The present invention describes a method of inducing lactation in non-human mammals by using a single administrations of an estrogen compound, a dopaminergic...
2017/0100452 METHODS AND COMPOSITIONS FOR THE TREATMENT OF AXONAL AND NEURONAL DEGENERATION
The present invention generally relates to methods and compositions for preventing or treating axonal and/or neuronal degeneration in a subject by...
2017/0100451 METHODS FOR THE PREVENTION OR TREATMENT OF VESSEL OCCLUSION INJURY
This invention provides methods of preventing or treating cardiac ischemia-reperfusion injury in a mammalian subject. The methods comprise administering to the...
2017/0100450 METHODS FOR PREVENTING OR TREATING INSULIN RESISTANCE
The invention provides methods of preventing or treating insulin resistance in a mammalian subject. The methods comprise administering to the subject an...
2017/0100449 Combination
The present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. In particular, the method...
2017/0100448 TREATMENT OF THE COMPLICATIONS OF CHRONIC LIVER DISEASE WITH CASPASE INHIBITORS
Provided herein are methods and compositions for treatment of a portal hypertension and cirrhosis by administering a of a caspase inhibitor alone or in...
2017/0100447 COMPOSITIONS BASED ON PLANT EXTRACTS FOR INHIBITION OF THE 5-ALPHA REDUCTASE
The present invention refers to nutraceutical, cosmetic or pharmaceutical compositions based on a combination of vegetal extracts from flowers or fruits of...
2017/0100446 PHARMACEUTICAL COMPOSITIONS COMPRISING PLANT EXTRACTS AND METHODS FOR REDUCING DURATION OF A COMMON COLD USING SAME
The present disclosure describes pharmaceutical compositions and methods for reducing duration, intensity, and/or bothersomeness of common colds in humans and...
2017/0100445 USE OF FREE RADICAL SCAVENGERS FOR PROTECTING AND TREATING SKIN AND HAIR DAMAGES CAUSED BY CHEMOTHERAPY
The present invention relates to the use of one or more free radical scavengers as prophylactically or therapeutically effective substances and microparticles...
2017/0100444 SALT-FREE MISO PRODUCTION METHOD, SALT-FREE MISO, HEPATIC FUNCTION IMPROVEMENT AGENT, AND HYPERTENSION...
Provided are: a production method for salt-free miso, in which steamed soy beans and koji are pressurized, heated, and fermented; salt-free miso obtained by...
2017/0100443 MEDICINAL COMPOSITION HAVING ANTIBIOTIC, ANTI-INFLAMMATORY, AND WOUND HEALING ACTIVITY
A medicinal composition having antibiotic, anti-inflammatory, and wound healing activity that inhibits the growth of pathogens by means of a synergistic...
2017/0100442 BI-LAYER DUAL RELEASE PROBIOTIC TABLETS
The present invention generally relates to dietary supplement and pharmaceutical formulations comprising layered acid protective oral dosage formulations...
2017/0100441 COMPOSITION FOR TREATMENT OF VITILIGO
A composition for treating vitiligo and a method of making the same, said composition comprising: a blue scorpion venom; and an alpha lipoic acid. Preferably,...
2017/0100440 AMNIOTIC FLUID TOPICAL FORMULATION
A human amniotic fluid formulation has been developed for topical application to the eye, which is useful for the treatment of ocular diseases and injuries...
2017/0100439 AMNIOTIC FLUID FORMULATION FOR TREATMENT OF JOINT PAIN OR DISORDERS
A human amniotic fluid formulation has been developed for administration into a joint or associated soft tissue such as a tendon or ligament for treatment of...
2017/0100438 TREATMENT OF GLIOMA BY ANTI-ANGIOGENIC ACTIVE IMMUNIZATION FOR DIRECT TUMOR INHIBITION AND AUGMENTATION OF...
Disclosed are compositions of matter, therapeutic protocols, and immunization means to induce an active immune response to vasculature feeding glioma or other...
2017/0100437 IN VITRO MODEL FOR NEURONAL DEATH
This invention demonstrates the formation of a novel polarized membrane lipid raft signaling module in neurons, in response to several diverse neurotoxic...
2017/0100436 LINEAGE DIFFERENTIATION OF ENCAPSULATED EMBRYONIC STEM CELLS
This application discloses alginate microencapsulation-mediated differentiation of embryonic stem cells and use of the stem cell differentiation method for the...
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