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Patent # Description
2017/0100435 THERAPEUTIC ENCAPSULATED MESENCHYMAL STROMAL CELLS
This application discloses a micro-encapsulation system for immobilizing mesenchymal stromal cells (MSCs) while sustaining the molecular communication. Thus,...
2017/0100434 MANAGEMENT OF ISCHEMIA USING POOLED MESENCHYMAL STROMAL CELL COMPOSITION
The present disclosure relates to composition comprising pooled and expanded allogeneic mesenchymal Stromal cells (MSCs) and a method for management of...
2017/0100433 MODIFIED NATURAL KILLER CELLS HAVING ANTI-FUGETACTIC PROPERTIES AND USES THEREOF
This invention provides ex vivo methods for making modified natural killer cell compositions having overall anti-fugetactic properties for the effective and...
2017/0100432 ANTIGEN SPECIFIC TOLEROGENIC ANTIGEN PRESENTING CELLS AND RELATED USES COMPOSITIONS, METHODS AND SYSTEMS
The present disclosure relates to antigen specific tolerogenic antigen presenting cells presenting antigenic portions of an autoantigen and to related...
2017/0100431 PHARMACEUTICAL COMPOSITIONS
Pharmaceutical compositions for oral administration, in particular administration as an oral delivery system to be swallowed directly or capable of...
2017/0100430 NANOCERIA FOR THE TREATMENT OF OXIDATIVE STRESS
A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and...
2017/0100429 Methods of Treating Diarrhea in Neonatal and Young Non-Human Animals
Methods of treating neonatal and young non-human animals suffering from diarrhea, and/or symptoms thereof, by administering to an animal in need thereof a...
2017/0100428 REGULATORS OF ANAPLASTIC LYMPHOMA KINASE AND USES THEREOF
Provided herein are ALK regulators for the treatment of diseases and disorders. For example, presented herein are ALK regulators, e.g., ALK activators, and...
2017/0100427 POLYSACCHARIDE PARTICLE MIXTURE
Tissue and other body structures may be protected using a dry, free-flowing, sterilized mixture of chitosan particles and oxidized polysaccharide particles in...
2017/0100426 NUTRITIONAL COMPOSITION
A nutrient composition, a lipid metabolism-improving agent, and prophylactic and/or therapeutic agents typically for inflammatory bowel diseases, immune...
2017/0100425 BETA-GLUCAN IN COMBINATION WITH ANTI-CANCER AGENTS AFFECTING THE TUMOR MICROENVIRONMENT
The present invention relates to the combination of soluble .beta.-glucan and anti-cancer agents that affect the tumor microenvironment. Soluble .beta.-glucan...
2017/0100424 BETA-GLUCAN METHODS AND COMPOSITIONS THAT AFFECT THE TUMOR MICROENVIRONMENT
This disclosure relates to the combination of soluble .beta.-glucan and immune suppression-relieving agents that affect the tumor microenvironment. Soluble...
2017/0100423 COMPOSITIONS FOR USE IN CARDIOPLEGIA COMPRISING ESMOLOL AND ADENOSINE
The invention related to a composition for use in cardioplegia, said composition comprising (i) esmolol; and (ii) adenosine, wherein in use the concentration...
2017/0100422 Solid Composition Comprising Amorphous Sofosbuvir
A solid composition comprising sofosbuvir and at least one pharmaceutically acceptable matrix compound wherein at least 99 weight-% of the sofosbuvir comprised...
2017/0100421 Compatible Composition Containing Chinese Medicine Cichorium Glandulosum Boiss Et Hout As Lipid-Lowering Active...
Disclosed are a compound pharmaceutical composition containing Cichorium glandulosum Boiss et Hout as a lipid-lowering active ingredient and the use of the...
2017/0100420 SUSTAINED RELEASE OF ANTIINFECTIVES
Provided, among other things, is a method of treating or ameliorating pulmonary infection in a cystic fibrosis patient comprising pulmonary administration of...
2017/0100419 NGNA COMPOSITIONS AND METHODS OF USE
The present invention relates to the field of viral disorders, and in particular to the use of natural compounds to inhibit viruses and viral infection....
2017/0100418 MALARIA TRANSMISSION PREVENTION AGENT HAVING RARE SUGAR AS EFFECTIVE COMPONENT THEREOF AND MALARIAL PARASITE...
Problem: A malaria transmission blocker or a malaria parasite growth inhibitor is provided as a result of finding a druq which inhibits malaria parasite growth...
2017/0100417 DOSAGE FORMS FOR ORAL ADMINISTRATION OF ZOLEDRONIC ACID OR RELATED COMPOUNDS FOR TREATING DISEASE
Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, such as zoledronic acid in an acid or a salt form, or in a molecular...
2017/0100416 OSTEOCLAST INHIBITORS FOR KNEE CONDITIONS
Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, such as zoledronic acid in an acid or a salt form, or in a molecular...
2017/0100415 Method of Treating Acute Coronary Syndromes
The present invention relates to methods and compositions designed for the treatment or management of acute coronary syndromes, particularly, unstable angina...
2017/0100414 SMALL MOLECULE EFFLUX PUMP INHIBITORS
Small molecule efflux pump inhibitors are provided, as well as methods for their use in treating infections. Also provided herein are methods of using the...
2017/0100413 COMPOSITION FOR REDUCING THE FREQUENCY OF URINATION, METHOD OF MAKING AND USE THEREOF
Pharmaceutical compositions for reducing frequency of urination are disclosed. The pharmaceutical compositions comprise one or more analgesic agents and a PDE5...
2017/0100412 OPHTHALMOLOGIC IRRIGATION SOLUTIONS AND METHOD
Solutions for perioperative intraocular application by continuous irrigation during ophthalmologic procedures are provided. These solutions include multiple...
2017/0100411 CORTICOSTEROID FORMULATIONS FOR MAINTAINING CORTICOSTEROID SYNOVIAL FLUID CONCENTRATIONS
This invention relates to compositions and methods for achieving and maintaining maximal analgesic effect following intra-articular administration of...
2017/0100410 Use of Medications with Neuroprotective Properties to Prevent or Reduce the Risk of Ischemia-Reperfusion Injury...
Provided are methods for treatment and prevention of ischemia-reperfusion injury and chronic intermittent hypoxia related injury through administering a...
2017/0100409 THERAPEUTIC AGENT FOR OCULAR FUNDUS DISEASE
Disclosed herein is a prophylactic or therapeutic agent for ocular fundus disease, especially diabetic retinopathy or age-related macular degeneration. The...
2017/0100408 IVABRADINE ADSORBATES
The subject-matter of the present invention is a novel, non-salified ivabradine solid form, in particular an ivabradine form adsorbed on an inert carrier. The...
2017/0100407 SKIN-PENETRATING FORMULATION OF TAUROLIDINE
A composition comprising: hydrolysable taurolidine; and a hydrolysable lipophilic excipient; wherein the hydrolysable taurolidine is contained within the...
2017/0100406 COMBINATIONS OF AN FGFR INHIBITOR AND AN IGF1R INHIBITOR
The invention relates to a combination of a FGFR inhibitor and an IGF1R inhibitor. The combination is for use in the treatment of a proliferative disorder, in...
2017/0100405 HSPC-Sparing Treatments for RB-Positive Abnormal Cellular Proliferation
This invention is in the area of improved compounds for and methods of treating selected RB-positive cancers and other Rb-positive abnormal cellular...
2017/0100404 CRYSTALLINE FORMS OF A BRUTON'S TYROSINE KINASE INHIBITOR
Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)pi- ...
2017/0100403 PEMETREXED DIPOTASSIUM FORMULATIONS
The present application provides pharmaceutical compositions derived from pemetrexed dipotassium Nonahydrate and its process thereof. The present application also...
2017/0100402 COMBINATIONS OF CANCER THERAPEUTICS
The invention relates to combinations of 4-[(S)-2-Azetidin-1-yl-1-(4-chloro-3-trifluoromethyl-phenyl)-ethylamino]-- quinazoline-8-carboxylic acid amide and/or...
2017/0100401 Treating Cancer With Drug Combinations
Embodiments of the invention find application in the field of cancer therapy. Receptor protein kinases (RPTKs) transmit extracellular signals across the plasma...
2017/0100400 INHIBITORS OF INFLUENZA VIRUSES REPLICATION
Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological...
2017/0100399 Microbicidal Pyrimidine Or Triazine Containing Compounds
The present invention concerns the microbicidal activity of certain pyrimidine or triazine containing non-nucleoside reverse transcriptase inhibitors. The...
2017/0100398 COMBINATIONS OF A PYRIMIDINE CONTAINING NNRTI WITH RT INHIBITORS
The present invention concerns combinations of a pyrimidine containing NNRTI with nucleoside reverse transcriptase inhibitors and nucleotide reverse...
2017/0100397 HETEROARYL COMPOUNDS AND USES THEREOF
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
2017/0100396 PYRROLOPYRAZINE DERIVATIVES FOR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA
The present invention relates to a compound having the general formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph,...
2017/0100395 COMBINATIONS COMPRISING BREXPIPRAZOLE OR A SALT THEREOF AND A SECOND DRUG FOR USE IN THE TREATMENT OF A CNS...
The present invention provides a medicament having a wider treatment spectrum, causing a fewer side effects and superior in tolerability and safety, as...
2017/0100394 ANTHELMINTIC COMPOUNDS
The present invention relates to novel anthelmintic compounds of formula (I) below: ##STR00001## wherein Y and Z are independently a bicyclic carbocyclic or a...
2017/0100393 COMPOSITIONS, PACKAGED PHARMACEUTICALS, AND METHODS OF USING HEDGEHOG PATHWAY MODULATORS FOR THE SENSITIZATION...
Compositions, packaged pharmaceuticals, and methods of treatment by the sensitization of resistant tumors are provided. The compositions comprise a combination...
2017/0100392 Treating Sexual Desire Disorders with Flibanserin
The invention relates to the use of fibanserin, or a pharmaceutically acceptable acid addition salt thereof, for the treatment of disorders of sexual desire.
2017/0100391 Compositions And Kits Useful For Treatment Of Respiratory Illness
A stable liquid composition in a clear bottle where the composition contains, at least, phenylephrine and acetaminophen. The composition is substantially free...
2017/0100390 POLYSUBUNIT OPIOID PRODRUGS RESISTANT TO OVERDOSE AND ABUSE
The invention provides compositions and methods for the treatment or prevention of pain. The invention provides constructs whereby hydrolysis of the construct...
2017/0100389 TETRAHYDROPROTOBERBINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF NEUROLOGICAL, PSYCHIATRIC AND...
Tetrahydroprotoberbine (THPB) compounds and their use in the treatment of neurological, psychiatric and neurodegenerative diseases is provided. The compounds...
2017/0100388 USE OF LAQUINIMOD TO DELAY HUNTINGTON'S DISEASE PROGRESSION
The subject invention provides methods of treating or delaying disease progression in a subject afflicted with Huntington's disease (HD) comprising...
2017/0100387 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING ATRIAL FIBRILLATION
The present invention provides compositions and methods for treating or preventing atrial fibrillation (AF). In particular, the present invention provides...
2017/0100386 NOVEL COMPOUNDS FOR TREATMENT OF CYSTIC FIBROSIS
A corrector agent capable of stabilizing a newly synthesized cystic fibrosis transmembrane conductance regulator (CFTR) protein, useful in the treatment of...
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