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Patent # Description
2017/0100385 PHARMACEUTICAL COMPOSITIONS COMPRISING DANIRIXIN FOR TREATING INFECTIOUS DISEASES
Provided are compounds and pharmaceutically acceptable salts thereof, and combinations of compounds, their pharmaceutical compositions, their methods of...
2017/0100383 TOPICAL FORMULATIONS FOR PREVENTING SKIN INFECTION
A topical formulation comprising a first active agent that is pharmaceutically acceptable salt of a cationic bisbiguanide such as chlorhexidine digluconate...
2017/0100382 HYDROXYPYRIDONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC USE FOR TREATING...
Provided herein are hydroxypyridone derivatives, for example, a compound of Formula I, and pharmaceutical compositions thereof. Also provided herein are...
2017/0100381 PIRFENIDONE TREATMENT FOR PATIENTS WITH ATYPICAL LIVER FUNCTION
Methods are provided for administering pirfenidone to a patient that has exhibited abnormal biomarkers of liver function in response to pirfenidone...
2017/0100380 PHARMACEUTICAL COMPOSITION CONTAINING AS AN ACTIVE INGREDIENT 5-METHYL-1-PHENYL-2-(1H)-PYRIDONE
A tablet characterized by comprising 5-methyl-1-phenyl-2-(1H)-pyridone as the main ingredient and, based on the main ingredient, 10 to 50 wt. % excipient, 5 to...
2017/0100379 AMIDINE SUBSTITUTED BETA-LACTAM COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS
The present invention relates to novel .beta.-lactam compounds, their preparation and use. In particular, this invention relates to novel .beta.-lactam...
2017/0100378 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF MYELODYSPLASTIC SYNDROMES
The present invention provides methods and pharmaceutical compositions designed to intervene in this defective process and to promote or restore erythrocyte...
2017/0100377 Solid Oral Pharmaceutical Compositions for Isoxazoline Compounds
A solid oral pharmaceutical composition for delivery of a pharmaceutically acceptable active ingredient to an animal where the composition comprises an...
2017/0100376 Solid Dosage Forms of Bendamustine
In the present invention there is provided a pharmaceutical composition in a solid dosage form suitable or oral administration, the composition comprising...
2017/0100375 COMPOSITIONS AND METHODS COMPRISING 2-(ACYLAMINO)IMIDAZOLES
The present invention presents 2-(acylamino)imidazoles with therapeutic activity, including selective activity against cancer cells, and compositions...
2017/0100374 POTENTIATOR-CORRECTOR COMBINATIONS USEFUL IN THE TREATMENT OF CYSTIC FIBROSIS
A combination therapy including a modulator of the function (potentiator) of cystic fibrosis transmembrane conductance regulator (CFTR) protein, and one or two...
2017/0100373 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND
The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as an agent for the...
2017/0100372 COMPOSITION COMPRISING BIO COMPOUND FOR TREATING CARDIOVASCULAR DISEASE
A pharmaceutical composition and a method for preventing or treating a cardiovascular disease are provided. The pharmaceutical composition includes a BIO...
2017/0100371 COMPOSITIONS AND METHODS FOR TREATING ESTROGEN-RELATED MEDICAL DISORDERS
Disclosed herein are methods for treatment of estrogen-related medical disorders. The methods of treatment may comprise administering to a subject in need of...
2017/0100370 COMPOSITIONS AND METHODS FOR CANCER THERAPY
The invention provides compositions and methods to treat a hyperproliferative disorder with ascorbate or a pharmaceutically acceptable salt thereof, at least...
2017/0100369 PHARMACEUTICAL COMPOSITIONS COMPRISING ONE OR MORE PYRONE COMPOUNDS, AND THEIR USE FOR TREATING INFLAMMATORY...
Provided herein are pharmaceutical compositions, each comprising a pyrone compound, for example, a compound of Formula I, and a pharmaceutically acceptable...
2017/0100368 USE OF ERIBULIN AND POLY (ADP RIBOSE) POLYMERASE (PARP) INHIBITORS AS COMBINATION THERAPY FOR THE TREATMENT OF...
The invention features methods for treating cancer in a patient in need thereof by administering eribulin, in combination with one or more PARP inhibitors,...
2017/0100367 USE OF ERIBULIN IN THE TREATMENT OF CANCER
The invention features methods and kits for use in treating cancer in a patient in need thereof by administering eribulin or a pharmaceutically-acceptable salt...
2017/0100366 TREATMENT OF CIRCADIAN RHYTHM DISORDERS
Embodiments of the invention relate to the use of a melatonin agonist in the treatment of free running circadian rhythms in patients, including light...
2017/0100365 METHOD FOR TREATING PROSTATE CANCER AND/OR GASTROINTESTINAL CANCER
Gold(III) complexes having mixed ligands as anticancer agents. The gold(III) complexes are coordinated to bidentate ligands having diamino functional groups: a...
2017/0100364 PHARMACEUTICAL COMPOSITION FOR TREATING INFLAMMATION AND PAIN
The present invention is directed to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and 3-(methylthio)propionitrile, or a...
2017/0100363 COMPOSITIONS COMPRISING EICOSAPENTAENOIC ACID AND A HYDROXYL COMPOUND AND METHODS OF USE THEREOF
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or...
2017/0100362 FUMARATE ESTER DOSAGE FORMS
Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In...
2017/0100361 FUMARATE ESTER DOSAGE FORMS
Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In...
2017/0100360 FUMARATE ESTER PHARMACEUTICAL COMPOSITIONS
Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In...
2017/0100359 Succinate Prodrugs for Use in the Treatment of Lactic Acidosis or Drug-Induced Side-Effects Due to Complex...
The present invention relates to a succinate prodrug for use in the treatment or prevention of lactic acidosis.
2017/0100358 USE OF RETINOIC ACID AND ANALOGS THEREOF TO TREAT CENTRAL NEURAL APNEAS
Described is a method of inhibiting central apnea, central hypopnea or obstructive sleep apnea in a mammal. The method includes the step of administering to a...
2017/0100357 ANTIMICROBIAL COMPOSITIONS CONTAINING FREE FATTY ACIDS
The invention concerns antimicrobial compositions comprising free fatty acids emulsified with membrane lipids or hydrolysed derivatives thereof, and...
2017/0100356 NOVEL FORMULATION OF DICLOFENAC
The present invention relates to methods for producing particles of diclofenac using dry milling processes as well as compositions comprising diclofenac,...
2017/0100355 PHARMACEUTICAL FORMULATION
A formulation for oral administration comprises an expectorant, an analgesic, and at least one additional active ingredient having a modified release providing...
2017/0100354 COMPOSITIONS AND METHODS FOR TREATING KABUKI SYNDROME AND RELATED DISORDERS
A method is provided for treating a Mendelian disorder of the epigenetic machinery (e.g., Kabuki syndrome) in a subject in need thereof. In particular, the...
2017/0100353 COMPOSITIONS AND METHODS THAT TARGET OLFACTORY RECEPTORS FOR REGULATION OF BREATHING
The olfactory receptor Olfr78/OR51E2 is shown to be expressed in the carotid body and to control breathing responses regulated by acute hypoxia sensing....
2017/0100352 Methods for treating or preventing neuroinflammation or autoimmune diseases
Disclosed herein are ribonucleotide reductase inhibitors, compositions comprising ribonucleotide reductase inhibitors, and methods for treating and/or...
2017/0100351 EXTENDED-RELEASE FORMULATION FOR REDUCING THE FREQUENCY OF URINATION AND METHOD OF USE THEREOF
Methods and compositions for reducing the frequency of urination are disclosed. One method comprises administering to a subject in need thereof an effective...
2017/0100350 EXTENDED RELEASE COMPOSITIONS OF AN AMINOALKYL NITRATE
The present invention relates to extended release compositions of an amino-C2-C6-alkyl nitrate and of pharmaceutically acceptable salt thereof, in particular...
2017/0100349 ORGANOSULFUR COMPOUNDS FOR THE PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES
Divalent salts of S-allylmercapto-N-acetylcysteine and related compositions are disclosed which can be administered in order to provide protection from the...
2017/0100348 Treatment Regime for Chronic Sinusitis
The present invention discloses an invention comprising a treatment regime for chronic sinusitis. The regime includes destruction of biofilm and prevention of...
2017/0100347 Zeaxanthin Formulations With Additional Ocular-Active Nutrients, For Protecting Eye Health And Treating Eye...
Oral formulations for promoting eye health, and in particular for preventing or treating macular degeneration, are disclosed, containing zeaxanthin, a...
2017/0100346 Transdermal Therapeutic System For Administering Rivastigmine Or Derivatives Thereof
The present invention relates to a transdermal therapeutic system for administering an active substance through the skin, comprising: a) a cover layer, b) a...
2017/0100345 WOUND HEALING USING BRAF INHIBITORS
Methods for treating a wound are provided herein. Such methods include a step of contacting the wound with an effective amount of a BRAF inhibitor. In some...
2017/0100344 PRION FREE NANOPARTICLE COMPOSITIONS AND METHODS OF MAKING THEREOF
The present invention provides prion-free compositions comprising nanoparticles comprising albumin and substantially water insoluble drugs. Also provided are...
2017/0100343 CROSSLINKED PARTICLES
Disclosed are crosslinked particles (e.g., microparticles) that are capable of storing and releasing drugs. The particles can be macroparticles,...
2017/0100342 STABILIZED ASSEMBLED NANOSTRUCTURES FOR DELIVERY OF ENCAPSULATED AGENTS
A non-covalently assembled hydrogel or organo-gel composition with serum stability is described. Low molecular weight (<2,500 Da), generally regarded as...
2017/0100341 PHARMACEUTICAL COMPOSITIONS RESISTANT TO ABUSE
The present invention provides immediate release pharmaceutical compositions for oral administration that are resistant to abuse.
2017/0100340 PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF
The present invention relates to pharmaceutical compositions containing a solid dispersion of ...
2017/0100339 FORMULATIONS AND METHODS FOR CONTEMPORANEOUS STABILIZATION OF ACTIVE PROTEINS DURING SPRAY DRYING AND STORAGE
A method of treatment of plasma with a physiologically compatible spray dry stable acidic substance (SDSAS) prior to or contemporaneously with spray drying of...
2017/0100338 METHOD OF TREATING DIABETIC WOUNDS USING BIOSYNTHESIZED NANOPARTICLES
The method of treating diabetic wounds using biosynthesized nanoparticles includes administering an effective amount of silver and gold nanoparticles to a...
2017/0100337 Naltrexone hydrochloride compositions
The present invention relates to compositions and methods of stabilizing naltrexone hydrochloride.
2017/0100336 Fluoropolymer Emulsions with Perhalogenated Stabilizer for the Delivery of Hydrophobic Drugs
The present invention provides therapeutic formulations, including therapeutic nanoemulsions, and related methods for the in vivo delivery of hydrophobic...
2017/0100335 TOPICAL NANOEMULSION THERAPY FOR WOUNDS
The present invention relates to therapeutic nanoemulsion compositions and to methods of utilizing the same to treat a burn wound. In particular, nanoemulsion...
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