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Patent # Description
2017/0128580 TARGETED THERAPEUTICS
The present invention provides pharmacological compounds including an effector moiety conjugated to a binding moiety that directs the effector moiety to a...
2017/0128579 METHOD OF SYNTHESIZING POLYSACCHARIDE CONJUGATES AND METHOD FOR CANCER THERAPY
A method of synthesizing a polysaccharide conjugate used for cancer therapy is provided. The method comprises the following steps. A polysaccharide having at...
2017/0128578 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES
The present invention provides for a derivative of monoterpene or sesquiterpene, such as a perillyl alcohol derivative. For example, the perillyl alcohol...
2017/0128577 SURFACE MODIFIED NANOCRYSTALLINE CELLULOSE AND USES THEREOF
The present disclosure relates to surface modified nanocrystalline cellulose (NCC) prepared by chemical modification of NCC as well as its use thereof,...
2017/0128576 ENTERIC ELASTOMERS
Enteric elastomers and related methods are generally provided. In some embodiments, the enteric elastomer is a polymer composite. Certain embodiments comprise...
2017/0128575 LIQUID PHARMACEUTICAL FORMULATIONS OF PEMETREXED
The present invention provides stable liquid pharmaceutical formulation of pemetrexed or pharmaceutically acceptable salts thereof comprises at least one...
2017/0128574 WATER-SOLUBLE SUPRAMOLECULAR COMPLEXES
Water-soluble supramolecular complexes formed from a water soluble block copolymer and at least one associative gelling adjuvant. The copolymer includes at...
2017/0128573 MULTIMODAL THERAPY FOR CANCER CELL DESTRUCTION
The field of the disclosure relates generally to cancer cell destruction and, more specifically, to cancer cell destruction by photo-magnetic irradiation...
2017/0128572 LONG-LIVED GADOLINIUM BASED TUMOR TARGETED IMAGING AND THERAPY AGENTS
Alkylphosphocholine analogs incorporating a chelating moiety that is chelated to gadolinium are disclosed herein. The alkylphophocholine analogs are compounds...
2017/0128571 MAGNETIC PARTICLE CONTROL
Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator....
2017/0128570 ANNEXIN II COMPOSITIONS AND METHODS
The present invention provides compositions and methods that involve the 36 kDa annexin II monomer, which has been identified as having immunostimulatory...
2017/0128569 Engineered Cells Expressing Multiple Immunomodulators and Uses Thereof
This invention relates to the field of therapeutics. Most specifically invention provides methods of generating in vitro engineered immune cells conditionally...
2017/0128568 Calcium Flux Agonists And Methods Therefor
Calcium flux agonists are used to enhance a TLR- or NOD-mediated stimulus and to so increase an immune response of a host and reduce healing time. Preferred...
2017/0128567 Vaccine Adjuvants
The present invention provides a new adjuvant for administering vaccines.
2017/0128566 ALLERGEN DESENSITIZATION METHOD
The present application relates to a method for desensitization of allergic patients. More specifically it relates to an epicutaneous desensitization method,...
2017/0128565 Methods of Treating CMV Retinitis by T Cell Therapy
Disclosed herein are methods of treating CMV (cytomegalovirus) retinitis in a human patient in need thereof, comprising administering to the human patient a...
2017/0128564 POLYPEPTIDE DERIVED FROM gp41, A VACCINE COMPOSITION COMPRISING SAID POLYPEPTIDE, AND USES FOR TREATING AN...
The present invention relates to the field of the in vitro diagnosis of the progression status of an infection of an individual with a virus belonging to the...
2017/0128563 Live Attenuated Classical Swine Fever Vaccine Based in Genetic Manipulation of a Putative Fusion Peptide Area...
The role of a specific E2 region, .sup.869CKWGGNWTCV.sup.878, containing a putative fusion peptide (FP) sequence was evaluated. FPs critically contribute to...
2017/0128562 POLYVALENT INFLUENZA VIRUS-LIKE PARTICLES (VLPS) AND USE AS VACCINES
This disclosure provides compositions that include a mixture of viral like particles (VLPs), expressing different individual influenza hemagglutinin (HA)...
2017/0128561 USE OF OIL AND WATER EMULSIONS FOR INCREASING B CELL RESPONSES WITH MODIFIED VACCINIA ANKARA VIRUS
The invention relates to compositions, uses, and methods for inducing an immune response against a vaccinia virus. The addition of an oil and water emulsion to...
2017/0128560 Attenuated Mannheimia haemolytica Vaccines and Methods of Making and Use
The present invention provides attenuated M. haemolytica strains that elicit an immune response in animals against M. haemolytica, compositions comprising said...
2017/0128559 CAPSULAR GRAM-POSITIVE BACTERIA BIOCONJUGATE VACCINES
The present invention encompasses a novel S. aureus bioconjugate vaccine. More generally, the invention is directed to Gram-positive and other bioconjugate...
2017/0128558 ANTI-MALARIA COMPOSITIONS AND METHODS
Described herein are multilayer films that include modified polypeptide epitopes from Plasmodium falciparum, specifically a modified T* epitope. The multilayer...
2017/0128557 Dendritic Cell Therapeutic Agent and Immunotherapeutic Agent Comprising Peptide Derived from Telomerase, and...
Provided is a dendritic cell therapeutic agent, and more particularly, a composition which include dendritic cells activated by peptides including a...
2017/0128556 IMMUNOTHERAPY USING T PRECURSOR CELLS DERIVED FROM PLURIPOTENT STEM CELLS HAVING REARRANGED T CELL RECEPTOR GENES
Provided is a method for immune cell therapy, which comprises generating T cell progenitors from pluripotent stem cells bearing rearranged T cell receptor...
2017/0128555 PLACENTAL COMPOSITIONS FOR STIMULATION OF IMMUNITY TO PD-L1
Disclosed is the new, useful, and unexpected finding that immunization to placental endothelial cells stimulated with interferon gamma result in antibodies to...
2017/0128554 Universal N-Glycan Binding Reagent
Methods of capturing N-glycan linked glycomolecules including N-glycans, N-glycopeptides and N-glycoproteins are described. The methods provide substantially...
2017/0128553 Compositions of Engineered Human Arginases and Methods for Treating Cancer
Compositions and methods for the treatment of cancer are described, and, more preferably, to the treatment of cancers that do not express, or are otherwise...
2017/0128552 METHODS FOR TREATING HEADACHE
A headache can be treated more effectively by co-administration of a botulinum toxin and a triptan drug to a patient and/or the effectiveness of a triptan...
2017/0128551 NOVEL USES OF RECOMBINANT CLOSTRIDIAL NEUROTOXINS WITH DECREASED DURATION OF EFFECT
This invention relates to novel uses of recombinant clostridial neurotoxins exhibiting decreased duration of effect, in particular uses for the treatment of...
2017/0128550 Stabilised Solid Compositions of Factor VII Polypeptides
The invention relates to chemically as well as physically stable compositions comprising Factor VII or a Factor VII-related polypeptide such that these...
2017/0128549 COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR IMMUNOSTIMULATION
The present invention relates to a complexed RNA, comprising at least one RNA complexed with one or more oligopeptides, wherein the oligopeptide, which has the...
2017/0128548 LACTOFERRIN SUPPLEMENTATION AND DIARRHEA
The present invention relates in general to the field of intestinal health. In particular, the present inventors have found that a composition comprising...
2017/0128547 Use of Hydrolytic and Oxidative Enzymes to Dissolve Biofilm in Ears
A composition for removal of biofilm in the ears is useful for the treatment of ear infections such as otitis media, particularly those infections caused by...
2017/0128546 Therapeutic Charge Engineered Variants of Lysozyme and Methods for Using Same to Treat Infections
The present invention is a genetically engineered version of a lysozyme protein wherein the engineered enzyme exhibits enhanced antimicrodial activity,...
2017/0128545 ALBUMIN NANOPARTICLES TO AUGMENT STEM CELL FUNCTION IN VIVO
The present invention relates to a product and method of using albumin nanoparticles for augmenting the function or effectiveness of stem cells or precursor...
2017/0128544 Uses of Humanized Cobra Venom Factor for Reducing or Preventing Immunogenicity
The embodiments herein are concerned with methods and hCVF compositions, including pharmaceutical formulations, useful in complement depletion, the reduction...
2017/0128543 METHODS OF TREATING ANOREXIA NERVOSA BY INTRANASAL ADMINISTRATION OF INSULIN
The present system is directed in several embodiments to a method of administration of a therapeutic composition for treatment of Anorexia Nervosa, safely and...
2017/0128542 NON-AQUEOUS GLUCAGON FORMULATIONS
Stabilized glucagon formulations are provided, in the form of a clear solution. The formulations include glucagon in a non-aqueous diluent and an antioxidant...
2017/0128541 NOVEL EXENATIDE ANALOGUE AND USE THEREOF
The present invention relates to a novel exenatide analogue, which is an exenatide analogue in which the first to fifteenth amino acids from the C-terminal of...
2017/0128540 EYE DROP FORMULATION
An ophthalmic composition for administration to an eye containing 0.001-1000 micrograms per ml by weight of thymosin beta 4 (T.beta.4), or an N-terminal...
2017/0128539 IL-2RBETA-SELECTIVE AGONISTS IN COMBINATION WITH AN ANTI-CTLA-4 ANTIBODY OR AN ANTI-PD-1 ANTIBODY
The invention relates to (among other things) method of administering to a patient suffering from a cancer, the method comprising the steps of: (a) an...
2017/0128538 METHODS FOR ASSESSING THE EFFICACY OF ANTI-INFLAMMATORY CYTOKINE COMPOSITIONS
Methods for generating an anti-inflammatory compositions. Methods include obtaining a biological material, determining input concentrations of an ...
2017/0128537 GCSF FOR USE IN THE TREATMENT OF NEUROGENIC IMMUNE SUPPRESSION AND/OR PREVENTION OF RELATED MEDICAL COMPLICATIONS
The present invention relates to Granulocyte colony-stimulating factor (GCSF) for use in the treatment of neurogenic immune depression syndrome, for use in the...
2017/0128536 NEW PHARMACEUTICAL COMPOSITIONS AND THEIR USE FOR THE TREATMENT OF AUTOIMMUNE DISORDERS
A pharmaceutical composition in which the active substance includes or is: (i) a protein including the sequence SEQ ID NO: 1, representing the APRIL protein,...
2017/0128535 TSLP INDUCES NEUTROPHIL MEDIATED KILLING OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS
The invention provides a method of promoting the host defense of a patient to a bacterial infection comprising administering to a patient suffering or at risk...
2017/0128534 TREATING ROTATOR CUFF CONDITIONS
This document provides methods and materials related to treating rotator cuff conditions (e.g., rotator cuff tendonitis or rotator cuff injuries such as...
2017/0128533 PROTECTION AGAINST APOPTOSIS FROM IONIZING RADIATION
The use and screening of modulators of apoptosis is disclosed. The modulators may be, for example, modulator of NF-.kappa.B activity. The modulators may be...
2017/0128532 Methods For The Prediction Of A Personalized ESA-Dose In The Treatment Of Anemia
The present invention pertains to the use of an Integrative pharmacokinetic/pharmacodynamic (PK/PD) ESA-EpoR mathematical model for calculating the binding...
2017/0128531 TREATING NEURODEGENERATIVE DISEASES WITH PROGRANULIN
The invention relates to methods and compositions for treating a neurodegenerative disease. More particularly, the present invention is directed to methods of...
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