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Patent # Description
2017/0128479 TREATMENT OF PEROXISOME BIOGENESIS DISORDER
A method is described for treating a peroxisome biogenesis disorder by administering to an individual in need thereof an effective amount of an autophagy...
2017/0128478 Skin Treatment Lotion
A system and method for a skin treatment lotion. The lotion has a protecting agent, a moisture absorber, a binding agent, water, and an antibiotic agent or...
2017/0128477 COMPOSITION FOR INHIBITING MYELOID-DERIVED SUPPRESSOR CELLS COMPRISING DECITABINE OR ITS PHARMACEUTICALLY...
The present invention relates to a method for inhibiting myeloid-derived suppressor cells or treating cancer comprising administering a pharmaceutical...
2017/0128476 FAP-Activated Therapeutic Agents, and Uses Related Thereto
Disclosed are prodrugs of anthracyclines (such as doxorubicin) and derivatives thereof that are selectively cleaved and activated by fibroblast activating...
2017/0128475 COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING ORGAN INJURY AND/OR DYSFUNCTION
The present embodiments relate to compositions and methods for treating the inflammatory response in a tissue or organ, such as the liver, by contacting the...
2017/0128474 METHOD FOR TREATING CANCER USING CHEMOKINE ANTAGONISTS
What is described is a method for treating cancer in a patient in need of such treatment through the use of an antagonist to CXCR1 and/or CXCR2 receptors by...
2017/0128473 Vesicular Formulations for Use in the Treatment of Pain or Reduced Mobility of a Joint
The present invention relates to vesicular formulations for use in the treatment of pain and/or reduced mobility associated with a loss of lubrication and/or...
2017/0128472 Administration of Zoledronic Acid to Treat Pain Associated with Ankylosing Spondylitis
Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, such as zoledronic acid in an acid or a salt form, can be used to...
2017/0128471 COMBINATION THERAPY TO TREAT MYCOBACTERIUM DISEASES
The present invention relates to a compound of formula (I) ##STR00001## or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The...
2017/0128470 COMPOSITIONS FOR ORAL ADMINISTRATION OF ZOLEDRONIC ACID OR RELATED COMPOUNDS FOR TREATING PAGET'S DISEASE OF BONE
Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, such as zoledronic acid in an acid or a salt form, or in a molecular...
2017/0128469 COMPOSITION CONTAINING PHYTIC ACID, MAGNESIUM AND POLYPHENOLS FOR THE TREATMENT OR PREVENTION OF RENAL LITHIASIS
The present invention is related to a composition comprising phytic acid or a phytate salt, magnesium in the form of salt, hydroxide or oxide and optionally at...
2017/0128468 PHOSPHATIDYLGLYCEROL AS AN ANTI-INFLAMMATORY
Compositions and methods for reducing, or inhibiting inflammation in a subject in need thereof have been developed. Pharmaceutical compositions including one...
2017/0128467 ANTIMICROBIAL PHARMACEUTICAL COMPOSITIONS WITH MULTIPLE DRUG RESISTANCE INHIBITING PROPERTIES
The invention provides a method for treating a microbial infection in an infected subject comprising administering to the subject an antimicrobial composition...
2017/0128466 USE OF CANTHAXANTHIN AND/OR 25-OH D3 FOR IMPROVED HATCHABILITY IN POULTRY
The present invention relates to the use canthaxanthin and/or 25-hydroxy vitamin D3 (25-OH D3) for improving breeder hatchability and fertility and for...
2017/0128465 Pharmaceutical Compositions and Methods
This invention relates the use of cortisol blockers (e.g., glucocorticoid receptor [GR] antagonists) for the treating or preventing viral infections, treating...
2017/0128464 Porous silicon drug-eluting particles
The invention provides a biodegradable drug-eluting particle useful for the delivery of diagnostic or therapeutic agents. In certain embodiments, the...
2017/0128463 ROCURONIUM PREPARATION WITH IMPROVED STABILITY
The present invention provides a rocuronium preparation with an excellent stability. The rocuronium preparation contains rocuronium and a buffer solution and...
2017/0128462 METHODS FOR TREATING FEMALE SEXUAL DYSFUNCTION WHILE DECREASING CARDIOVASCULAR RISK
Methods for treating female sexual dysfunction are provided. In particular, methods for treating a woman having HSDD by administering to the woman a...
2017/0128461 SHIP INHIBITION TO INDUCE EXPRESSION OF GRANULOCYTE COLONY STIMULATING FACTOR IN A SUBJECT
The present invention relates to the use SHIP inhibitors to induce expression of granulocyte colony stimulating factor (G-CSF) in a subject, thereby promoting...
2017/0128460 Cyclic Amines
The present invention is directed to novel cyclic amines which inhibit the P2X7 receptor.
2017/0128459 PHARMACEUTICAL COMPOSITION CONTAINING SIRT2 INHIBITOR
The present invention relates to a pharmaceutical composition containing a SIRT2 inhibitor and, more specifically, to: a pharmaceutical composition for...
2017/0128458 COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS
Compounds of formula (I), pharmaceutically acceptable salts thereof, and uses of the compounds of formula (I) for treating bacterial infections are disclosed. ...
2017/0128457 Treatment of Conditions Through Pharmacological Modulation of the Autonomic Nervous System
Methods are provided for treating a subject for a condition caused by an abnormality in the subject's autonomic nervous system. In accordance with the subject...
2017/0128456 CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF
Carbon monoxide-releasing organic molecules are described herein. The molecules can be synthesized prior to administration (e.g., ex vivo) or formed in vivo....
2017/0128455 COMBINATIONS OF MEDICAMENTS FOR THE TREATMENT OF RESPIRATORY DISEASES
A pharmaceutical composition comprising: (a) a compound of formula 1 ##STR00001## wherein: n is 1 or 2; R.sup.1 is hydrogen, halogen, C.sub.1-4-alkyl, or ...
2017/0128454 COMPOSITIONS AND METHODS FOR INHIBITING VIRAL POLYMERASE
Provided are compounds of Formula I: ##STR00001## as described herein. Compounds of Formula I are useful in methods of inhibiting viral RNA polymerase activity...
2017/0128453 NOVEL USES
The subject matter generally relates to methods of treatment and/or prophylaxis of CNS diseases, disorders, and/or injuries. In one aspect, the subject matter...
2017/0128452 Aminopterin Dosage Forms
Embodiments of the present invention provide dosage forms and methods for treating a patient with an inflammatory disorder with a therapeutically effective...
2017/0128451 DOSING REGIMEN ASSOCIATED WITH LONG ACTING INJECTABLE PALIPERIDONE ESTERS
The present invention provides a method of treating patients in need of treatment with long acting injectable paliperidone palmitate formulations.
2017/0128450 SMALL MOLECULE INHIBITORS OF INFLUENZA A RNA-DEPENDENT RNA POLYMERASE
Antiviral compositions and methods are contemplated that are especially effective in the treatment and prevention of influenza A viruses. Also presented are...
2017/0128449 MEDICINAL COMPOSITION INHIBITING NEOVASCULARIZATION PROLIFERATION FACTOR
A pharmaceutical composition for neovascular diseases, a pharmaceutical composition for inhibiting an angiogenic growth factor, and use of these pharmaceutical...
2017/0128447 Inhibitors of Multidrug Resistance Transporter P-Glycoprotein
The present disclosure provides a method of treating a subject that is resistant to one or more drugs by identifying a subject having one or more drug...
2017/0128446 USE OF BUSPIRONE METABOLITES
The present invention is directed to a composition comprising a buspirone metabolite, alone or in combination with a second active ingredient, for use in the...
2017/0128445 Fused Imidazole and Pyrazole Derivatives as Modulators of TNF Activity
A series of substituted benzimidazole, imidazo[1,2-.alpha.]pyridine and pyrazolo[1,5-.alpha.]pyridine derivatives, and analogues thereof, being potent...
2017/0128444 POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE
Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): ##STR00001## ...
2017/0128443 POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE
Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): ##STR00001## ...
2017/0128442 TRAZODONE AND TRAZODONE HYDROCHLORIDE IN PURIFIED FORM
A process of production of trazodone or trazodone hydrochloride that comprises: (a) preparing an organic phase comprising trazodone in at least one organic...
2017/0128441 PHARMACEUTICAL FOR TREATING DIZZINESS HAVING DIFFERENT CAUSES
The invention relates to a dosage form that is suitable for releasing an active ingredient over a long period of time. For this purpose, the active ingredient...
2017/0128440 TAMPER RESISTANT DOSAGE FORMS
The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of...
2017/0128439 NEW BRUTON'S TYROSINE KINASE INHIBITOR
The present invention provides a Bruton's tyrosine kinase inhibitor, which is a compound represented by formula (I) or a pharmaceutically acceptable salt,...
2017/0128438 Nano- And Micro-Sized Particles of 20-Camptothecin Or Derivative Thereof And Pharmaceutical Compositions...
A pharmaceutical composition is provided having particles of a physical mixture that contain at least one 20-camptothecin or a derivative thereof, at least one...
2017/0128437 AMINO-QUINOLINES AS KINASE INHIBITORS
Disclosed are compounds having the formula: ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3 and Z are as defined herein, and methods of making and using the same.
2017/0128436 Treatment of Glaucoma Using Laquinimod
The subject invention provides a method of treating a subject afflicted with glaucoma, suffering from retinal ganglion cell (RGC) loss or damage, or elevated...
2017/0128435 TREATMENT OF MULTIPLE SCLEROSIS WITH LAQUINIMOD
The subject invention provides for methods of reducing the relapse rate and/or reducing the accumulation of physical disability in a relapsing-remitting...
2017/0128434 NOVEL ESTROGEN RECEPTOR LIGANDS
Compounds of formula (I) or a pharmaceutically acceptable ester, amide, carbamate or salt thereof, including a salt of such an ester, amide or carbamate in...
2017/0128433 Inhibitors of the PP1/GADD34 Complex for the Treatment of a Condition Requiring an Immunosuppressive Activity
The present invention relates to the general field of treatment and prevention of diseases involving an inflammatory condition, namely sepsis or infectious or...
2017/0128432 COMPOSITIONS COMPRISING NICOTINIC AGONISTS AND METHODS OF USING SAME
The disclosure is directed at least in part to compositions and methods comprising nicotinic agonists for treating e.g., nervous system disorders, in...
2017/0128431 4-ALKYNYL IMIDAZOLE DERIVATIVE AND MEDICINE COMPRISING SAME AS ACTIVE INGREDIENT
There are provided 4-alkynylimidazole derivatives represented by the following general formula (I) or pharmaceutically acceptable salts thereof; the...
2017/0128430 UCP-1 Expression Promoter
It is intended to provide a drug, a quasi-drug, a dermatological preparation for external use, or a material to be contained to drugs, quasi-drugs,...
2017/0128429 Methods of Administering Pirfenidone Therapy
The present invention relates to methods involving avoiding adverse drug interactions with fluvoxamine and pirfenidone or other moderate to strong inhibitors...
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