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Patent # Description
2017/0130277 BIOMARKER FOR COLORECTAL CANCER
Methods of diagnosing colorectal cancer and precursors thereof using miRNA biomarkers are disclosed, together with kits and devices for detecting the...
2017/0130276 STOMACH CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD
This invention relates to a kit or a device for the detection of stomach cancer and a method for detecting stomach cancer, and provides a kit or a device for...
2017/0130275 BREAST CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD
It is intended to provide a kit or a device for the detection of breast cancer and a method for detecting breast cancer. The present invention provides a kit...
2017/0130274 COLORECTAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD
It is intended to provide a kit or a device for the detection of colorectal cancer and a method for detecting colorectal cancer. The present invention provides...
2017/0130273 ESOPHAGEAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD
It is intended to provide a kit or a device for the detection of esophageal cancer and a method for detecting esophageal cancer. The present invention provides...
2017/0130271 TUMOR SUPPRESSOR AND ONCOGENE BIOMARKERS PREDICTIVE OF ANTI-IMMUNE CHECKPOINT INHIBITOR RESPONSE
The present invention is based on the identification of novel biomarkers predictive of responsiveness to anti-immune checkpoint inhibitor therapies.
2017/0130270 METHOD FOR EXPECTING AND DIAGNOSING UQCRB-RELATED DISEASE
Disclosed is a method for expecting and diagnosing UQCRB-related disease, and more particularly, related to a method for diagnosing a UQCRB-related disease and...
2017/0130269 DIAGNOSIS OF NEUROMYELITIS OPTICA VS. MULTIPLE SCLEROSIS USING MIRNA BIOMARKERS
The invention relates to a method of diagnosis of neuromyelitis optica, in particular of differential diagnosis of neuromyelitis optica (NMO) vs. multiple...
2017/0130268 COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF BONE FRACTURES AND DISORDERS
The present invention relates to the therapy, prophylaxis and diagnosis of disorders that are associated with aberrant bone mineral density, in particular...
2017/0130267 METHODS FOR PREDICTING ACUTE REJECTION IN HEART RECIPIENTS
The present invention relates to method for predicting acute rejection in heart recipients. In particular, the present invention relates to a method for...
2017/0130266 METHODS AND SYSTEMS FOR PREDICTING THE RISK OF TRANSGENE SILENCING
The present invention is based on the use of the H3K9me2 methylation levels in plant genomes to predict transgene silencing, transgene stability, and/or...
2017/0130265 SINGLE NUCLEOTIDE DETECTION METHOD
A method of sequencing a nucleic acid such as DNA or RNA is provided. It is characterised by the steps of (1) generating a stream of single nucleoside...
2017/0130264 NOVEL COMPOSITIONS, METHODS AND KITS FOR ENHANCING PCR SPECIFICITY
The present disclosure provides novel primers and method for the detection of specific nucleic acid sequences. The primers and methods provided herein are...
2017/0130263 METHODS AND MATERIALS FOR ASSESSING ALLELIC IMBALANCE
Methods and systems for detecting allelic imbalance using nucleic acid sequencing are provided.
2017/0130262 GENOMIC ANALYSIS DEVICE AND METHODS OF USE
Aspects of the present disclosure include a complete genomic analysis device and methods of use thereof for high throughput genomic analysis of biological...
2017/0130261 NUCLEIC ACID AMPLIFICATION DEVICE, NUCLEIC ACID AMPLIFICATION METHOD, AND CHIP FOR NUCLEIC ACID AMPLIFICATION
The present invention provides a reciprocal-flow-type nucleic acid amplification device comprising: heaters capable of forming a denaturation temperature zone and...
2017/0130260 METHODS AND COMPOSITIONS FOR PREPARING SEQUENCING LIBRARIES
Embodiments provided herein relate to methods and compositions for next generation sequencing. Some embodiments include the preparation of a template library...
2017/0130259 METHODS FOR MULTIPLEXING AMPLIFICATION REACTIONS
A two-step multiplex amplification reaction includes a first step which truncates the standard initial multiplex amplification round to "boost" the sample copy...
2017/0130258 MULTIPLEX ON-ARRAY DROPLET PCR AND QUANTITATIVE PCR
This present disclosure provides methods and compositions for multiplex amplification, e.g., PCR, of DNA samples compartmentalized on the surface of an array....
2017/0130257 HIGH-PERFORMANCE EMPIRICAL ANALYSIS OF METABOLIC PATHWAYS IN MICROALGAE USING CELL-FREE SYSTEM
For more efficient and high-performance analysis of a function of a microalgae gene, the present invention provides an empirical analysis method of a metabolic...
2017/0130255 ENZYMES AND POLYMERASES FOR THE SYNTHESIS OF RNA
The invention relates to compositions and methods for the design, evolution, preparation, and/or manufacture of enzymes for use with polynucleotides, primary...
2017/0130254 NUCLEOTIDE PRODUCTION PROCESS
A nucleotide production process comprises: decomposing an RNA by using a nuclease P1 so as to obtain nucleotides AMP, GMP, CMP and UMP, converting part or all...
2017/0130253 Method for Improving GlcNAc Production of Recombinant Bacillus Subtilis
The invention provides an effective method for improving N-acetylglucosamine (GlcNAc) production by engineered B. subtilis Deletion of phosphoenolpyruvate...
2017/0130252 PROCESSING BIOMASS
Biomass (e.g., plant biomass, animal biomass, microbial, and municipal waste biomass) is processed to produce useful products, such as food products and amino...
2017/0130251 METHOD FOR FERMENTING SUGARS USING GENETICALLY ENGINEERED YEAST
A fermentation process for fermenting a starch hydrolysate containing 60-98 weight percent of glucose based on total carbohydrate and 0.3-5% weight percent of...
2017/0130250 Compositions and Methods For Making (S)-Norcoclaurine and (S)-Norlaudanosoline, and Synthesis Intermediates Thereof
Methods that may be used for the manufacture of the chemical compound (S)-norcoclaurine, (S)-norlaudanosoline, and (S)-norcoclaurine or [S]-norlaudanosoline...
2017/0130249 (R)-SELECTIVE NITROALDOL REACTION CATALYSED BY PROTEINS OF THE CUPIN SUPERFAMILY
The present invention relates to a method for producing chiral .beta.-nitro alcohol compounds. The invention relates in particular to an (R)-selective...
2017/0130248 Byosynthetic Production of Acyl Amino Acids
The present invention relates to a cell for producing acyl glycinates wherein the cell is genetically modified to comprise at least a first genetic mutation...
2017/0130247 COMPOSITIONS AND METHODS FOR ALTERING GENE EXPRESSION
Provided herein are improved compositions and methods for the directed control of gene expression.
2017/0130246 TRANS-ACTING ELEMENTS FOR INTRACELLULAR DELIVERY OF NUCLEIC ACID SEQUENCES
Compounds of the formula (Z).sub.x wherein: each Z is independently selected from 2'-deoxythymidinyl moiety, 2'-deoxyadenosinyl moiety, and a ...
2017/0130245 CHIMERIC CAPSIDS
The present invention relates to viral vectors and methods of their production and use.
2017/0130244 NOVEL PROMOTERS FOR HIGH LEVEL EXPRESSION
The present invention provides for functional chimeric gene regulatory units capable of driving strong and sustained heterologous gene expression.
2017/0130243 SHIBIRE/DYNAMIN NUCLEIC ACID MOLECULES TO CONTROL COLEOPTERAN AND HEMIPTERAN PESTS
This disclosure concerns nucleic acid molecules and methods of use thereof for control of insect pests through RNA interference-mediated inhibition of target...
2017/0130242 PLANTS HAVING ALTERED AGRONOMIC CHARACTERISTICS UNDER NITROGEN LIMITING CONDITIONS AND RELATED CONSTRUCTS AND...
Isolated polynucleotides and polypeptides, and recombinant DNA constructs useful for conferring improved nitrogen use efficiency and/or drought stress...
2017/0130241 PLANT TYPE RELATED PROTEIN, AND CODING GENE AND APPLICATION THEREOF
A plant type related protein, and a coding gene and an application thereof are provided. The protein is: (a) a protein consisting of the amino acid sequence of...
2017/0130240 GENERATION OF PLANTS WITH ALTERED PROTEIN, FIBER, OR OIL CONTENT
The present invention is directed to plants that display an improved oil quantity phenotype or an improved meal quality phenotype due to altered expression of...
2017/0130239 REDUCTION OF NICOTINE TO NORNICOTINE CONVERSION IN PLANTS
The present invention relates to a mutant, non-naturally occurring or transgenic tobacco plant cell comprising: (i) a polynucleotide comprising, consisting or...
2017/0130238 DEVICE AND METHODS FOR BIOLISTIC TRANSFORMATION
The present invention provides an innovate method and device for depositing coated particles to prepare sample cartridges for use in a gene gun. It allows for...
2017/0130237 Methods and Compositions for Delivering Nucleic Acids to Plant Cells and Regulating Gene Expression
Transfection of plant cells with dsRNA through foliar application encounters cuticle, cell wall and plasmalemma three major barriers. We developed cationic...
2017/0130236 METHODS OF PLANT TRANSFORMATION USING TRANSFORMABLE CELL SUSPENSION CULTURE AND USES THEREOF
The subject invention pertains to a method of rapidly transforming a plant with a gene of interest. The method of the current invention comprises the steps of...
2017/0130235 METHOD FOR FINE-TUNING GENE EXPRESSION LEVELS USING SYNTHETIC REGULATORY SRNA
The present invention relates to a method for fine-tuning gene expression levels using a synthetic regulatory sRNA in a prokaryotic cell. The present invention...
2017/0130234 MICROORGANISMS FOR THE PRODUCTION OF ADIPIC ACID AND OTHER COMPOUNDS
The invention provides a non-naturally occurring microbial organism having an adipate, 6-aminocaproic acid or caprolactam pathway. The microbial organism...
2017/0130233 YEAST STRAIN AND MICROBIAL METHOD FOR PRODUCTION OF PENTACYCLIC TRITERPENES AND/OR TRITERPENOIDS
The invention relates to a yeast strain and to a method for microbial production of pentacyclic triterpenes and/or triterpenoids in yeast. More particularly,...
2017/0130232 Methods for Immortalization of Epithelial Cells
Methods for inducing non-clonal immortalization of normal epithelial cells by directly targeting the two main senescence barriers encountered by cultured...
2017/0130231 NOVEL DOUBLE-STRANDED OLIGO RNA AND PHARMACEUTICAL COMPOSITION COMPRISING SAME FOR PREVENTING OR TREATING...
The present invention relates to a novel siRNA, and a high-efficiency double-stranded oligo RNA structure containing the same, and a nanoparticle containing...
2017/0130230 METHODS OF USING PVT1 EXON 9 TO DIAGNOSE AND TREAT PROSTATE CANCER
PVT1 exon 9 is overexpressed in aggressively tumorigenic prostate cancer cell lines and prostate tumor tissues. This exon provides a diagnostic tool for the...
2017/0130229 METHODS AND COMPOSITIONS FOR INHIBITING INFECTION BY INFLUENZA AND VIRUSES
The disclosure provides methods and compositions for inhibiting or treating influenza comprising an miRNA that promotes Bcl-2 inhibition or mTOR/PI3K...
2017/0130228 COMPOSITIONS AND METHODS TO ACTIVATE OR INHIBIT TOLL-LIKE RECEPTOR SIGNALING
The present invention includes compositions and methods of inhibiting or activating TLR7 signaling. In one aspect, a composition includes an inhibitor of TLR7...
2017/0130227 APTAMERS SPECIFIC FOR TLR-4 AND USES THEREOF
The invention relates to a nucleic acid aptamer with the capability of binding specifically to and inhibiting TLR-4, to a complex comprising said aptamer and a...
2017/0130226 APTAMERS AGAINST EGFR AND THERAPEUTIC USES THEREOF
The invention relates to novel aptamers, in particular aptamers which are capable of binding to EGFR. The invention also relates to cancer cell binding...
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