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Patent # Description
2017/0137897 GENETIC MARKERS FOR MYB28
The present invention relates to a method for determining the genotype of a Cruciferous vegetable plant for a plant with an increased glucosinolate level,...
2017/0137896 METHODS AND COMPOSITIONS FOR IDENTIFYING YEAST
The invention relates to a method of identifying a specific yeast species in patient tissue or body fluid. The method comprises the steps of extracting and...
2017/0137895 METHODS OF IDENTIFYING ENZYMES AND MICROORGANISMS
The invention provides a method of identifying a microorganism that expresses a nucleic acid-modifying enzyme, in sample, the method comprising: (a) contacting...
2017/0137894 Oligonucleotides and Methods for Detecting KRAS and PIK3CA Mutations
Provided are oligonucleotides that are capable of detecting KRAS and PIK3CA mutations in both cancer patients and healthy individuals with high specificity in...
2017/0137893 PROGNOSTIC MEAN TELOMERE LENGTH
The disclosure concerns a prognostic method for determining at least one, or a combination, of the following: time to first treatment, response to treatment or...
2017/0137892 EXOSOME-ASSOCIATED MICRORNA AS A DIAGNOSTIC MARKER
The presently disclosed subject matter provides methods of diagnosis of cancer or adverse pregnancy outcomes in a subject by measuring amounts of one or more...
2017/0137891 INTEGRATION OF TUMOR CHARACTERISTICS WITH BREAST CANCER INDEX
Methods of determining risk of recurrence of a breast cancer of a subject are provided. Also provided are methods of predicting responsiveness to a therapy of...
2017/0137890 CANCER PROGNOSIS SIGNATURES
The disclosure provides for molecular classification of disease and, particularly, molecular markers for breast cancer prognosis and methods and systems of use...
2017/0137889 RAF1 FUSIONS
The invention provides to RAF1 gene fusions, RAF1 fusion proteins, and fragments of those genes and polypeptides. The invention further provides methods of...
2017/0137888 METHOD AND COMPOSITIONS FOR DETECTING EPIDERMAL GROWTH FACTOR RECEPTOR VARIANT FORMS IN CANCER CELLS
Method and compositions for screening for the presence of Epidermal Growth Factor Receptor variant 3 (EGFR(v3)) in a sample are described. The method comprises...
2017/0137887 MECP2E1 GENE
The invention is a novel MECP2E1 splice variant and its corresponding polypeptide. The invention also includes methods of using these nucleic acid sequences...
2017/0137886 PHYSIOGENOMIC METHOD FOR PREDICTING DRUG METABOLISM RESERVE FOR ANTIDEPRESSANTS AND STIMULANTS
Disclosed herein are compositions and methods relevant to a novel Drug Metabolism Reserve Physiotype to determine the metabolic capacity of a human individual....
2017/0137885 GENE EXPRESSION PROFILES ASSOCIATED WITH SUB-CLINICAL KIDNEY TRANSPLANT REJECTION
By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have...
2017/0137884 BCR-ABL TRUNCATION MUTATIONS
Truncation variants of BCR-ABL mRNA that produces BCR-ABL proteins with a truncated C-terminus and its role in resistance to treatment with kinase inhibitors...
2017/0137883 METHOD FOR DIAGNOSING SUBCLINICAL AND CLINICAL ACUTE REJECTION BY ANALYSIS OF PREDICTIVE GENE SETS
Disclosed herein are methods for diagnosing acute cellular rejection (ACR) of an allograft by analysis of predictive gene sets and kits for practicing these...
2017/0137882 METHODS FOR NON-INVASIVE DETECTION OF TRANSPLANT HEALTH OR REJECTION
The present invention relates to the technical field of organ and tissue transplantation and specifically to methods allowing rejection of transplanted organs...
2017/0137881 MITOCHONDRIAL MARKERS OF NEURODEGENERATIVE DISEASES
Disclosed is an in vitro method to diagnose or determine the risk of developing a neurodegenerative disease in a subject based on the determination of the...
2017/0137880 METHOD FOR TREATING DEPRESSION AND MAJOR DEPRESSIVE DISORDER
The present invention provides methods for treating depression such as major depressive disorder (MDD) in an individual. The invention further provides methods...
2017/0137879 METHODS FOR THE DIAGNOSIS OF METABOLIC DISORDERS USING EPIMETABOLIC SHIFTERS, MULTIDIMENSIONAL INTRACELLULAR...
Methods and formulations for diagnosing metabolic disorders in humans using epimetabolic shifters, multidimensional intracellular molecules or environmental...
2017/0137878 METHODS OF USING NUCLEOTIDE ANALOGUES
The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3'-O position capped by a group...
2017/0137877 INTEGRATED ANALYTICAL SYSTEM AND METHOD
An analytical assembly within a unified device structure for integration into an analytical system. The analytical assembly is scalable and includes a...
2017/0137876 METHODS OF INCREASING SEQUENCING ACCURACY
The present invention provides methods of increasing sequencing accuracy. For example, the methods of the invention use linear amplification to generate a...
2017/0137875 METHODS AND KITS FOR REDUCING ADAPTER-DIMER FORMATION
The current teachings relate to methods for reducing adapter-dimer formation, particularly when preparing nucleic acids of interest for subsequent...
2017/0137874 SOLID PHASE ISOTHERMAL AMPLIFICATION
Provided herein are methods and kits for isothermal nucleic acid amplifications that use a target nucleic acid template; a reaction mixture comprising a DNA...
2017/0137873 METHODS FOR DETERMINING SEQUENCE PROFILES
Provided herein are methods for analyzing a signature sequence in a nucleic acid sample by rapid sequencing of a target nucleic acid region. The method...
2017/0137872 STRATEGIES FOR HIGH THROUGHPUT IDENTIFICATION AND DETECTION OF POLYMORPHISMS
The invention relates to a method for the high throughput identification of single nucleotide polymorphisms by performing a complexity reduction on two or more...
2017/0137871 INTEGRATED PURIFICATION AND MEASUREMENT OF DNA METHYLATION AND CO-MEASUREMENT OF MUTATIONS AND/OR MRNA...
In various embodiments methods of determining methylation of DNA are provided. In one illustrative, but non-limiting embodiment the method comprises i)...
2017/0137870 NUCLEIC ACID SAMPLE PREPARATION
The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods,...
2017/0137869 METHODS FOR SYNTHESIZING NUCLEOTIDE ANALOGUES WITH DISULFIDE LINKERS
The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3'-O position capped by a group...
2017/0137868 PROCESS CONTROL STRAINS AND METHODS OF DETECTING
Provided herein are methods for determining the concentration of a microbe in a sample using a genetically engineered microbe as a process control strain. The...
2017/0137867 Methods for the diagnosis of bacterial vaginosis
The present invention relates to methods for the diagnosis of bacterial vaginosis based on an analysis of a patient sample. For example, patient test samples...
2017/0137866 METHODS AND COMPOSITIONS FOR LABELING NUCLEIC ACIDS
The present invention relates to methods for the labeling of nucleic acid polymers in vitro and in vivo. Certain methods are provided that include a [3+2]...
2017/0137865 RESTRICTION MEDIATED QUANTITATIVE POLYMERASE CHAIN REACTIONS
The present invention relates to the technical field of nucleic acid amplification using a Polymerase Chain Reaction (PCR). Specifically, the present invention...
2017/0137864 HIGH-THROUGHPUT AND HIGHLY MULTIPLEXED IMAGING WITH PROGRAMMABLE NUCLEIC ACID PROBES
The present invention provides, inter alia, methods and compositions for imaging, at high spatial resolution, targets of interest.
2017/0137863 Self-Immolative Probes for Enzyme Activity Detection
Provided is a compound having the structure: (SIG)-(SI-MOD).sub.m where SIG is a signaling molecule, SI is a self-immolative structure bound to SIG such that SIG...
2017/0137862 CHEMILUMINESCENT COMPOSITIONS, METHODS, ASSAYS AND KITS FOR OXIDATIVE ENZYMES
Chemiluminescent compositions, methods, assays and kits for oxidative enzymes are described. Further disclosed are dioxetane compounds of the form: ...
2017/0137861 MICROFLUIDIC DEVICE
A microfluidic device (1) comprises a substrate (10) transparent for imaging and having a plurality of spatially defined and separated cell channels (20)...
2017/0137860 METHODS FOR MODULATING PROTEIN GLYCOSYLATION PROFILES OF RECOMBINANT PROTEIN THERAPEUTICS USING MONOSACCHARIDES...
The present invention relates to the field of protein production, and in particular to methods and compositions for modulating glycosylation of proteins...
2017/0137859 DNA TEMPLATES FOR SMALL RNA PRODUCTION IN MAMMALIAN CELLS
This disclosure describes unique single stranded DNA templates having a characteristic sequence and secondary structure. The DNA templates disclosed herein are...
2017/0137858 Methods for High Fidelity Production of Long Nucleic Acid Molecules
In a method for generating an elongated nucleic acid molecule, a nucleic acid addition of a first nucleic acid molecule attached to a first 3' or 5' protecting...
2017/0137857 METHOD FOR IN VIVO PRODUCTION OF GLYCOSAMINOGLYCANS
The present invention relates to a method for in vivo production of glycosaminoglycans (GAG), by metabolic engineering in a genetically modified cell. In a...
2017/0137856 L-arabinose Isomerase Variants with Improved Conversion Activity and Method for Production of D-tagatose Using them
The present invention relates to the development of an L-arabinose isomerase variant from Thermotoga neapolitana DSM 5068, which is a kind of thermophile, on...
2017/0137855 RECOMBINANT CELLS AND METHODS FOR NONPHOSPHORYLATIVE METABOLISM
This disclosure describes methods for screening heterologous coding regions (e.g., a single gene coding region, and operon, or other gene cluster) for the...
2017/0137854 MICROORGANISM OF THE GENUS ESCHERICHIA PRODUCING L-TRYPTOPHAN AND METHOD FOR PRODUCING L-TRYPTOPHAN USING THE SAME
The present application relates to a microorganism of the genus Escherichia producing L-tryptophan and, more specifically, to a microorganism of the genus...
2017/0137853 MICROORGANISM PRODUCING O-ACETYL-HOMOSERINE AND METHOD FOR PRODUCING O-ACETYLHOMOSERINE USING THE SAME
The present disclosure relates to a microorganism producing O-acetylhomoserine with high efficiency and a method for producing O-acetylhomoserine and...
2017/0137852 PROCESS FOR PRODUCTION AND EXTRACTION OF DIHYDROLIPOIC ACID
A process for production and extraction of dihydrolipoic acid (DHLA) relates to the biotransformation of R-lipoic acid to dihydrolipoic acid. The process...
2017/0137851 REDUCING INSOLUBLE DEPOSIT FORMATION IN ETHANOL PRODUCTION
The present inventors have surprisingly discovered that phytic acid tenaciously precipitates with soluble metals in food or fuel ethanol-processing fluid,...
2017/0137850 METHODS FOR PRODUCING BIODIESEL BY RECOMBINANT LIPASE
A method for producing biodiesel is provided, which includes providing a recombinant Candida rugosa lipase; reacting the recombinant C. rugosa lipase and a...
2017/0137849 PROCESS FOR THE MANUFACTURE OF BUTANOL OR ACETONE
A process for the manufacture of butanol, acetone and/or other renewable chemicals is provided wherein the process utilises one or more of the group comprising...
2017/0137848 IBE FERMENTATION METHOD
The present invention concerns a process for the production of an aqueous mixture comprising isopropanol, n-butanol and ethanol, comprising a step in which an...
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