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Patent # Description
2017/0136131 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF
The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them.
2017/0136130 HUMAN ANTIBODY DRUG CONJUGATES AGAINST TISSUE FACTOR
Antibody drug conjugates against tissue factor. Also disclosed are pharmaceutical compositions comprising the antibodies and antibody drug conjugates, and...
2017/0136129 Stabilised Formulations of RNA
The present invention relates to stable low-salt aqueous formulations of particles comprising a polycation, preferably protamine, and RNA, which formulations...
2017/0136128 UPTAKE OF PHARMACEUTICALS WITHIN CYCLODEXTRIN-BASED POROUS MATERIALS
Pharmaceutical complexes composed of drug molecules entrapped in cyclodextrin-based MOFs (CD-MOFs) are provided. Pharmaceutical tablets incorporating crystals...
2017/0136127 HYDROGELS FOR TREATING AND AMELIORATING CANCERS AND POTENTIATING THE IMMUNE SYSTEM AND METHODS OF MAKING AND...
In alternative embodiments, provided are pharmaceutical compositions, formulations, kits and other products of manufacture, comprising a sterile hydrogel...
2017/0136126 Medication With A Reduced Bitter Taste Perception
A liquid medication with reduced bitterness containing a drug active and polyquaternium-2, polyquaternium-17, and/or polyquaternium-18.
2017/0136125 Solid Pharmaceutical Compositions Containing Pregabalin
A solid pharmaceutical composition containing pregabalin is described. The composition includes a matrix forming agent and a swelling agent and is suitable for...
2017/0136124 STRETCHABLE BACKING LAYERS FOR TRANSDERMAL DRUG DELIVERY SYSTEMS
Stretchable, occlusive backing layers for transdermal drug delivery systems are disclosed, that maintain occlusivity after stretching. The backing layers are...
2017/0136123 STANNOUS DOPED MICRO AND NANO PARTICLES FOR AUGMENTED RADIOFREQUENCY ABLATION
A composition for facilitating localized delivery of energy and of therapeutic agents to a lesion in tissue is disclosed comprising nanoparticles of a...
2017/0136122 PURIFIED ANTIBODY COMPOSITION
The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one...
2017/0136121 RNA VACCINES
A RNA vaccine containing a RNA molecule encoding an allergen or derivative thereof, in which the allergen is an allergen of Alnus glutinosa, Alternaria...
2017/0136120 INDUCTION OF IMMUNE RESPONSE
Provided are methods and compositions that can he used to treat subjects having a viral infection by provoking an immune response using newly discovered...
2017/0136119 Pharmaceutical Compositions Comprising CpG Oligonucleotides
The present invention provides a pharmaceutical composition for inducing immune response in a subject, comprising: (a) an antigen with a concentration ranging...
2017/0136118 NEUTRALIZING MOLECULES TO VIRAL ANTIGENS
The present invention concerns methods and means for identifying, producing, and engineering neutralizing molecules against influenza A viruses, and to the...
2017/0136117 EFFECTIVE VACCINATION AGAINST PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME (PRRS) VIRUS PRIOR TO WEANING
The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North...
2017/0136116 North American Porcine Reproductive and Respiratory Syndrome (PRRS) Virus and Uses Thereof
The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North...
2017/0136115 TRANSGENIC PLANTS EXPRESSING A TETRAVALENT CHIMERIC DENGUE VIRUS ANTIGEN TO PRODUCE EFFECTIVE VACCINES DERIVED...
The present invention generally relates to the field of plant molecular biology and biotechnology as it applies to the production of plant-derived vaccines....
2017/0136114 VACCINE
The present invention provides an attenuated African Swine Fever (ASF) virus which lacks a functional version of the following genes: multigene-family 360...
2017/0136113 EXOTOXIN/THERMOLYSIN COMPOSITIONS AND METHODS AND USES FOR TREATING OR PREVENTING LAMINITIS
The disclosure relates to immunogenic and vaccine compositions comprising Streptococcus exotoxins and/or bacterial thermolysins from M4 protease family. Also...
2017/0136112 COMPOSITIONS AND METHODS FOR TREATMENT OF MICROBIAL INFECTIONS
The present invention relates to methods and compositions for treatment of microbial infections and for the enhancement of resistance to infection. The...
2017/0136111 VACCINES COMPRISING HEAT-SENSITIVE TRANSGENES
The present disclosure provides temperature sensitive essential nucleic acid molecules from a psychrophilic bacterium, proteins encoded by the nucleic acid...
2017/0136110 NOVEL METHODS FOR INDUCING AN IMMUNE RESPONSE
Methods and uses are provided for inducing an immune response comprising at least two administrations of an immunogenic composition, wherein a lower dose is...
2017/0136109 DNA VECTOR AND TRANSFORMED TUMOR CELL VACCINES
Customized whole cell cancer vaccines can be produced from autologous (ex vivo or in situ) or allogeneic human or veterinary patient cell lines. Cells are...
2017/0136108 NOVEL PEPTIDES, COMBINATION OF PEPTIDES AND SCAFFOLDS FOR USE IN IMMUNOTHERAPEUTIC TREATMENT OF VARIOUS CANCERS
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2017/0136107 USE OF METALLOPROTEINASE INHIBITORS AGAINST BACTERIAL INFECTIONS
A composition comprising as components a polypeptide IMPI.alpha. (including wild type) and/or a polypeptide IMPI.alpha.-fusion and at least one antibiotic...
2017/0136106 BOTULINUM TOXIN ADMINISTRATION FOR TREATMENT OF NEUROGENIC DETRUSOR OVERACTIVITY ASSOCIATED URINARY INCONTINENCE
Methods for treating urinary incontinence associated with neurogenic detrusor overactivity (NDO) and for reducing need for or frequency of clean intermittent...
2017/0136105 METHODS AND COMPOSITIONS FOR TREATING SKIN CONDITIONS ASSOCIATED WITH VASCULAR HYPER-REACTIVITY
The present invention provides a methods and compositions for treating a patient having a skin condition characterized by vascular hyper-reactivity, such as...
2017/0136104 GLYCOPEGYLATED FACTOR IX
Conjugates between Factor IX and PEG moieties. are disclosed in the present application. The conjugates are linked via a glycosyl linking group interposed...
2017/0136103 WOUND DEBRIDEMENT COMPOSITIONS CONTAINING SEAPROSE AND METHODS OF WOUND TREATMENT USING SAME
Wound debridement compositions containing the proteolytic enzyme Seaprose and use of such compositions in wound treatment for the enzymatic debridement of wounds.
2017/0136102 PHAGE-DERIVED COMPOSITIONS FOR IMPROVED MYCOBACTERIAL THERAPY
Methods and compositions for the treatment of mycobacteria infections, particularly antibiotic resistant strains. Of particular use in treating tuberculosis...
2017/0136101 Methods for preventing and/or treating nasal polyps and rhinosinusitis
The invention is directed to methods for preventing and/or treating nasal polyps. The invention is further directed to methods for preventing and/or treating...
2017/0136100 Thioredoxin or Thioredoxin Derivatives or Peptides for the Treatment of High Blood Pressure
The present invention provides methods and compositions for the treatment of cardiovascular disorders comprising: a therapeutically effective amount of...
2017/0136099 SURFACTANT PROTEIN D FOR THE TREATMENT OF DISORDERS ASSOCIATED WITH LUNG INJURY
Surfactant protein D (SP-D) is a member of the collectin family of collagenous lectin domain-containing proteins that is expressed in epithelial cells of the...
2017/0136098 METHODS FOR TREATING NEUROLOGICAL CONDITIONS AND COMPOSITIONS AND MATERIALS THEREFOR
The present invention generally relates to methods, compositions and materials for treatment of and promotion of neurological functional recovery from...
2017/0136097 Rapid-acting insulin composition comprising a substituted citrate
A composition, in the form of an aqueous solution, including an insulin in hexameric form and at least one substituted citrate of formula I: ##STR00001## in...
2017/0136096 Insulin-Containing Prolonged-Action Preparation
The invention relates to the field of biotechnology and medicine, and specifically to insulin-containing injectable formulations used, in particular, for...
2017/0136095 Methods of Treatment Using A Pentapeptide Derived From The C-Terminus Of Glucagon-Like Peptide 1 (GLP-1)
Methods of treating obesity, metabolic syndrome, hepatic and non-hepatic steatosis, and diabetes using a pentapeptide, LVKGRamide, derived from the C-terminus...
2017/0136094 METHOD OF TREATMENT OF DIABETES TYPE 2 COMPRISING ADD-ON THERAPY TO INSULIN GLARGINE AND METFORMIN
A method for the treatment of diabetes mellitus type 2 comprising administering (d) desPro.sup.36Exendin-4(1-39)-Lys.sub.6-NH.sub.2 or/and a pharmaceutically...
2017/0136093 METHOD FOR PREVENTING OR TREATING OCULAR DISORDERS
A method for treating ocular-disorders which, involve angiogenesis or neovascularization as part of their pathologic process. These types of retinal disorders...
2017/0136092 FORMULATIONS OF ACTIVE AGENTS FOR SUSTAINED RELEASE
The present invention provides pharmaceutical formulations for sustained release when administered at cold temperatures, and methods for delivering a treatment...
2017/0136091 FOOD CONTAINING PROLACTIN
A nutritional composition for a subject, comprising prolactin identical or similar or analogous to prolactin found in a natural food source, and at least one...
2017/0136090 Angiopoietin-Based Interventions for Treating Cerebral Malaria
The present invention provides methods for treating, preventing or reducing the severity of cerebral malaria. The methods of the present invention comprise...
2017/0136089 COMPOSITIONS AND METHODS OF REGULATING BONE RESORPTION
The present invention includes compositions and methods that take advantage of MFG-E8's role as a homeostatic regulator of osteoclasts for treating a bone...
2017/0136088 PROBIOTIC FUNCTION OF HUMAN INTELECTIN
The present disclosure provides for methods providing a pre/probiotic agent to a subject. Human Intelectin 1 (hIntL-1) has been shown to bind selectively to...
2017/0136087 MULTIFUNCTIONAL BIODEGRADABLE PEG NANOCARRIER-BASED HYDROGELS FOR PREVENTING HIV TRANSMISSION
A multifunctional polyethylene glycol-based hydrogel that includes a multi-arm polyethylene glycol cross-linking unit covalently bound to at least four...
2017/0136086 Topical Compositions And Methods For Treating Wounds
In various embodiments, the present invention relates to a topical pharmaceutical composition for treating a skin condition, comprising a combination of...
2017/0136085 TARGETED THERAPEUTICS
The present invention provides pharmacological compounds including a peptide epoxy ketone protease inhibitor conjugated to a binding moiety that directs the...
2017/0136084 INHIBITORS OF IAP
Novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies and have the general formula I: ##STR00001## wherein R.sup.1, R.sup.2,...
2017/0136083 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING SENILE DEMENTIA AND PREPARATION METHOD THEREOF
The present disclosure relates to a pharmaceutical composition for preventing and treating senile dementia and preparation method thereof. The active...
2017/0136082 WATER EXTRACTS OF CINNAMON AND RADIX ASTRAGALI
This invention relates to methods and compositions for providing improved insulin-sensitivity and/or enhanced insulin-like action, which leads to improved...
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