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Patent # Description
2017/0152546 Direct Nucleic Acid Amplification Kit, Reagent and Method
The present invention relates to compositions, methods and kits which can be used to amplify nucleic acids with the advantage of decreasing user time and...
2017/0152545 COMPOSITIONS AND METHODS FOR OBTAINING NUCLEIC ACIDS FROM SPUTUM
The present invention relates to compositions and methods for preserving and extracting nucleic acids from saliva. The compositions include a chelating agent,...
2017/0152544 Process for Producing Substrate Solution for Measuring Lipase Activity, and Method for Simplifying Production
Provided is a process for producing a substrate solution for measuring lipase activity including, as a substrate for measuring lipase activity, ...
2017/0152543 SYSTEM AND METHOD FOR IDENTIFICATION OF PROTEASE SUBSTRATES
The present disclosure provides a method of identifying a substrate for a protease including contacting a protease to one of a first array and a second array,...
2017/0152542 LOW GLUTEN YEAST HYDROLYSATES
The present invention relates to a process for preparing a yeast hydrolysate comprising less than 100 ppm gluten and at least 1 ppm gluten based on salt-free...
2017/0152541 REDUCTION OF OXIDATED METHIONINE PEPTIDES FOR MASS SPECTROMETRY
A method for preparing a methionine-containing peptide or protein for analysis by mass spectrometry includes incubating the methionine-containing peptide or...
2017/0152540 COMPOSITIONS AND METHODS FOR PRODUCING GLYCOPROTEINS
The present disclosure relates to methods of producing antibodies with increased levels of non-fucosylated glycoforms by culturing mammalian cells in culture...
2017/0152539 METHOD FOR THE PRODUCTION OF A LYSATE USED FOR CELL-FREE PROTEIN BIOSYNTHESES
The invention relates to a method for producing a lysate used for cell-fee protein biosynthesis, comprising the following steps: a) a genomic sequence in an...
2017/0152538 Biosynthesis of Oligosaccharides
The present invention relates to methods for production of 2'Fucosyllactose by a microbial system comprising a .alpha.-1,2 fucosyltransferase (FucT2)...
2017/0152537 PROCESSES FOR INCREASING BIOALCOHOL YIELD FROM BIOMASS
A process for increasing alcohol yield from biomass (the form or agro- or forest residue, grains, hops, etc.), involving multiple hydrodynamic cavitation...
2017/0152536 METHOD FOR TRANSFORMING LEVOGLUCOSENONE INTO 4-HYDROXYMETHYN BUTYROLACTONE OR 4-HYDROXYMETHYL BUTENOLIDE
The disclosure relates to a method for transforming levoglucosenone into 4-hydroxymethyl butyrolactone or 4-hydroxymethyl butenolide, comprising a step...
2017/0152535 RECOMBINANT STRAIN PRODUCING O-AMINOBENZOATE AND FERMENTATIVE PRODUCTION OF ANILINE FROM RENEWABLE RESOURCES...
The invention provides a recombinant microbial host cell capable of converting a raw material comprising a fermentable carbon substrate to o-aminobenzoate...
2017/0152534 Rumenic Acid Rich Conjugated Linoleic Acid
A process for preparing a conjugated linoleic acid (CLA) material that is enriched in the cis 9, trans 11 (rumenic acid) CLA isomer. The process involves...
2017/0152533 Engineered CO2-Fixing Chemotrophic Microorganisms Producing Carbon-Based Products and Methods of Using the Same
Disclosed herein are microorganisms containing exogenous or heterologous nucleic acid sequences, wherein the microorganisms are capable of growing on gaseous...
2017/0152532 PROCESSING BIOMASS
Biomass (e.g., plant biomass, animal biomass, microbial, and municipal waste biomass) is processed to produce useful products, such as food products and amino...
2017/0152531 PROCESS FOR PRODUCING GLUTARATE AND GLUTARIC ACID METHYL ESTER
This document describes biochemical pathways for producing 2,4-pentadienoyl-CoA by forming one or two terminal functional groups, comprised of carboxyl or...
2017/0152530 CHEMICAL ENGINEERING PROCESSES AND APPARATUS FOR THE SYNTHESIS OF COMPOUNDS
The present invention provides methods for producing cannabinoids and cannabinoid analogs as well as a system for producing these compounds. The inventive...
2017/0152529 Biological Production of Multi-Carbon Compounds from Methane
Multi-carbon compounds such as ethanol, n-butanol, sec-butanol, isobutanol, tert-butanol, fatty (or aliphatic long chain) alcohols, fatty acid methyl esters,...
2017/0152528 DELIVERY, ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION AND...
The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of...
2017/0152527 COMPOSITIONS FOR LINKING DNA-BINDING DOMAINS AND CLEAVAGE DOMAINS
Disclosed herein are compositions for linking DNA binding domains and cleavage domains (or cleavage half-domains) to form non-naturally occurring nucleases....
2017/0152526 ENGINEERING OF HUMANIZED CAR T-CELL AND PLATELETS BY GENETIC COMPLEMENTATION
Human or humanized tissues and organs suitable for transplant are disclosed herein. Gene editing of a host animal provides a niche for complementation of the...
2017/0152525 VECTORS WITH MODIFIED INITIATION CODON FOR THE TRANSLATION OF AAV-REP78 USEFUL FOR PRODUCTION OF AAV
The present invention relates nucleic acid constructs for the production of recombinant parvoviral (e.g. adeno-associated viral) vectors in insect cells, to...
2017/0152524 GENE THERAPY FOR NEUROMETABOLIC DISORDERS
The disclosure pertains to methods and compositions for treating disorders affecting the central nervous system (CNS). These disorders include neurometabolic...
2017/0152523 SERUM-FREE STABLE TRANSFECTION AND PRODUCTION OF RECOMBINANT HUMAN PROTEINS IN HUMAN CELL LINES
The present invention relates to an improved method for the serum-free production of an immortalized human cell line stably transfected under serum-free...
2017/0152522 METHOD OF REDUCING ACETYLATION IN PLANTS TO IMPROVE BIOFUEL PRODUCTION
The invention provides methods for engineering plants to have reduced levels of acetylation by decreasing expression of one or more Cas1L genes. Such plants...
2017/0152521 ISOLATED NOVEL NUCLEIC ACID AND PROTEIN MOLECULES FROM SOY AND METHODS OF USING THOSE MOLECULES TO GENERATE...
This disclosure provides purified nucleic acids and polypeptides. Also provided are transgenic plants, seeds, and plant cells containing DNA for expression of...
2017/0152520 COMPOSITIONS AND METHODS FOR EXPRESSING GENES IN ALGAE
The present application provides novel regulatory elements including promoter sequences from microorganisms. The application further discloses DNA constructs...
2017/0152519 SYNTHETIC GENE CLUSTERS
Methods for making synthetic gene clusters are described.
2017/0152518 OLIGONUCLEOTIDES FOR MAKING A CHANGE IN THE SEQUENCE OF A TARGET RNA MOLECULE PRESENT IN A LIVING CELL
The present invention relates to the field of gene therapy, more specifically to oligonucleotides for making a change in the sequence of a target RNA molecule...
2017/0152517 TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
The invention relates to a method for the treatment of amyotrophic lateral sclerosis (ALS). Specifically, the invention implements the use of an antisense...
2017/0152516 METHOD OF PRODUCING LIPID NANOPARTICLES FOR DRUG DELIVERY
What is described is a method for preparing a liposome that efficiently encapsulates a negatively charged therapeutic polymer, e.g., siRNA. The process...
2017/0152515 TREATMENT OF ATONAL HOMOLOG 1 (ATOH1) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO ATOH1
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Atonal homolog 1 (ATOH1), in particular, by...
2017/0152514 METHODS FOR TRIGGERING DE NOVO FORMATION OF HETEROCHROMATIN AND OR EPIGENETIC SILENCING WITH SMALL RNAS
The present application relates to a method for the targeted formation of heterochromatin and/or induction of epigenetic gene silencing in a cell using a small...
2017/0152513 MODULATION OF BCL11A FOR TREATMENT OF HEMOGLOBINOPATHIES
The invention relates to methods and uses of modulating fetal hemoglobin expression (HbF) in a hematopoietic progenitor cells via inhibitors of BCL11A...
2017/0152512 IMPROVED NANOPARTICLE TYPE OLIGONUCLEOTIDE STRUCTURE HAVING HIGH EFFICIENCY AND METHOD FOR PREPARING SAME
The present invention relates to an oligonucleotide structure and a method for preparing the same and, more particularly, to an oligonucleotide structure in...
2017/0152511 5' TARGETING OLIGONUCLEOTIDES FOR MODULATING RNA
Aspects of the invention relate to methods for increasing gene expression in a targeted manner. In some embodiments, methods and compositions are provided that...
2017/0152510 NEW METHOD FOR ISOLATING MICROBIAL DNA
The present invention relates to a new method for enriching and/or isolating nucleic acids from microbial cells which comprises filtering a liquid sample...
2017/0152509 METHOD FOR OPERATING MAGNETIC BODY PARTICLES AND DEVICE FOR OPERATING MAGNETIC BODY PARTICLES
A method for operating magnetic body particles that is for fixing a target substance in a liquid sample to the surface of the magnetic body particles; and a...
2017/0152508 Using Truncated Guide RNAs (tru-gRNAs) to Increase Specificity for RNA-Guided Genome Editing
Methods for increasing specificity of RNA-guided genome editing, e.g., editing using CRISPR/Cas9 systems, using truncated guide RNAs (tru-gRNAs).
2017/0152507 Delivery systems and kits for gene editing
The present disclosure relates to compositions and methods for modifying a gene sequence, and for systems for deliverying such compositions. For example, the...
2017/0152506 INACTIVATION OF LYMPHOCYTE IMMUNOLOGICAL CHECKPOINTS BY GENE EDITING
Disclosed are methods, protocols, and compositions of matter useful for generation of lymphocytes with permanently inactivated immunological checkpoint genes,...
2017/0152505 COUPLING ENDONUCLEASES WITH END-PROCESSING ENZYMES DRIVES HIGH EFFICIENCY GENE DISRUPTION
The present disclosure relates to the co-expression of an endonuclease with an end-processing enzyme for the purpose of enhanced processing of the...
2017/0152504 COUPLING ENDONUCLEASES WITH END-PROCESSING ENZYMES DRIVES HIGH EFFICIENCY GENE DISRUPTION
The present disclosure relates to the co-expression of an endonuclease with an end-processing enzyme for the purpose of enhanced processing of the...
2017/0152503 COUPLING ENDONUCLEASES WITH END-PROCESSING ENZYMES DRIVES HIGH EFFICIENCY GENE DISRUPTION
The present disclosure relates to the co-expression of an endonuclease with an end-processing enzyme for the purpose of enhanced processing of the...
2017/0152502 COUPLING ENDONUCLEASES WITH END-PROCESSING ENZYMES DRIVES HIGH EFFICIENCY GENE DISRUPTION
The present disclosure relates to the co-expression of an endonuclease with an end-processing enzyme for the purpose of enhanced processing of the...
2017/0152501 PROCESS FOR MANUFACTURING A COMPOSITE SORBENT MATERIAL FOR CHROMATOGRAPHICAL SEPARATION OF BIOPOLYMERS
The present invention relates to a sorbent material for separation and purification of biopolymers, particularly nucleic acids, having a solid support...
2017/0152500 METHOD OF DIFFERENTIATING ADULT STEM CELLS INTO NERVE CELLS BY USING HIGH-INTENSITY ELECTROMAGNETIC FIELD
The present invention relates to a method of differentiating mesenchymal stem cells or adult stem cells into nerve cells by treating the mesenchymal stem cells...
2017/0152499 PROCESS FOR GENERATION OF PROTEIN AND USES THEREOF
A method of generating a protein with an improved functional property, the method comprising: (a) identifying at least one Target amino acid Residue in a...
2017/0152498 VARIANTS OF EXOGLUCANASES HAVING IMPROVED ACTIVITY AND USES THEREOF
The present invention relates to the expression and optimisation of enzymes involved in the breakdown of lignocellulosic biomass. The present invention...
2017/0152497 VARIANTS OF EXOGLUCANASES HAVING IMPROVED ACTIVITY AND USES THEREOF
The present invention relates to the expression and optimisation of enzymes involved in the breakdown of lignocellulosic biomass. The present invention...
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