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Patent # Description
2017/0159133 MDM2-Containing Double Minute Chromosomes And Methods Therefore
Contemplated systems and methods allow for computational genomic analysis using paired-end sequence analysis and split read refinement to thereby identify...
2017/0159132 DETECTING METHYLATION IN A SUBPOPULATION OF GENOMIC DNA
This invention provides methods of determining the biological, pathological, genetic, epigenetic or disease status in a biological sample by determining the...
2017/0159131 PREDICTING CANCER OUTCOME
This document provides methods and materials related to assessing prostate cancer in mammals. For example, this document provides nucleic acids and...
2017/0159130 TRANSCRIPTIONAL CLASSIFICATION AND PREDICTION OF DRUG RESPONSE (T-CAP DR)
A method to predict the response. e.g., a strong positive response or a strong lack of responsive, of myeloma cells of a multiple myeloma patient to a...
2017/0159129 METHODS FOR DETECTING TELOMERE MAINTENANCE MECHANISMS
Presented herein are methods for detecting the activity of alternative lengthening of telomeres, a telomere maintenance mechanism, by measuring relative G-rich...
2017/0159128 METHOD FOR SELECTING PERSONALIZED TRI-THERAPY FOR CANCER TREATMENT
The present invention relates to a method for determining the best combinations of at least three drugs for treating cancer, which is based on the...
2017/0159127 AN IN VITRO DIAGNOSTIC METHOD OF CANCER
The present invention relates to an in vitro method for the diagnosis, prognosis and treatment of cancer through the analysis in a body fluid sample of the...
2017/0159126 GENE FOR PREDICTING THE PROGNOSIS FOR EARLY-STAGE BREAST CANCER, AND A METHOD FOR PREDICTING THE PROGNOSIS FOR...
The present invention relates to a method for selecting a gene intended to predict the prognosis for a cancer, to the selected gene for predicting the...
2017/0159125 MICRO-RNA BIOMARKERS FOR HAEMOLYSIS AND METHODS OF USING SAME
The present disclosure relates to micro-RNAs associated with haemolysis and methods of using them. One disclosed method is a procedure for identifying...
2017/0159124 EXAMINATION NOTIFICATION OUTPUT DEVICE, EXAMINATION NOTIFICATION OUTPUT METHOD, EXAMINATION NOTIFICATION OUTPUT...
There are provided an examination notification output device, an examination notification output method, an examination notification output program, and a gene...
2017/0159123 MICRORNAS AS NEW THERAPEUTIC TARGETS FOR THE PREVENTION AND/OR TREATMENT OF RETINOPATHY
Methods and compositions are disclosed to identify plasma and vitreous microRNA (miRNA) signatures of diabetic retinopathy (DR), and then as diagnostic...
2017/0159122 METHODS AND KITS FOR DETECTING GENETIC MARKERS FOR LITTER SIZE IN PIGS
Methods and kits useful for identifying a pig as producing an increased litter size are provided. Genetic makers, in particular SNP markers are provided that...
2017/0159120 HIGH THROUGHPUT SCREENING OF POPULATIONS CARRYING NATURALLY OCCURRING MUTATIONS
Efficient methods are disclosed for the high throughput identification of mutations in genes in members of mutagenized populations. The methods comprise DNA...
2017/0159119 METHODS AND COMPOSITIONS FOR LOADING OF POLYMERASE COMPLEXES
The present disclosure provides methods, compositions, and systems for distributing polymerase compositions into array regions. In particular, the described...
2017/0159118 SEQUENCING BY ORTHOGONAL SYNTHESIS
A method for sequencing includes steps of (a) providing first and second nucleic acid templates, wherein the two templates have different sequences; (b)...
2017/0159117 Nanopore-Based Single DNA Molecule Characterization, Identification and Isolation Using Speed Bumps
The present invention relates to a method of using nanopores to obtain sequence information of sample DNAs in ss test DNAs. The method comprises using speed...
2017/0159116 MODULAR NUCLEOTIDE COMPOSITIONS AND USES THEREFOR
Nucleic acid compositions, methods of making and using such compositions that comprise modular functional groups that can be configured to provide desired...
2017/0159115 SINGLE MOLECULE NUCLEIC ACID SEQUENCING WITH MOLECULAR SENSOR COMPLEXES
The present disclosure relates to methods and constructs for single molecule electronic sequencing of template nucleic acids. The constructs are molecular...
2017/0159114 GENETIC POLYMORPHISMS IN AGE-RELATED MACULAR DEGENERATION
Methods for determining whether a patient is at increased risk of developing wet AMD or whether a patient has an increased likelihood of benefiting from...
2017/0159113 METHODS AND COMPOSITIONS FOR DETECTION OF ANALYTES
The present invention relates to methods and compositions for detecting analytes, including proteins, polysaccharides, viruses, nucleic acids and cells. The...
2017/0159112 AMPLIFIED ISOTHERMAL DETECTION OF POLYNUCLEOTIDES WITH ATP RELEASE
The presence of a target polynucleotide sequence of interest, including targets comprising genetic variations or a single nucleotide polymorphism, is detected...
2017/0159111 FRET-LABELED COMPOUNDS AND USES THEREFOR
FRET-labeled compounds are provided for use in analytical reactions. In certain embodiments, FRET-labeled nucleotide analogs are used in place of naturally...
2017/0159110 SEQUENCES AND THEIR USE FOR THE DETECTION AND CHARACTERIZATION OF E. COLI O157:H7
This invention relates to a rapid method for detection and characterization of Escherichia coli bacteria serotype O157:H7 based on the presence of nucleic acid...
2017/0159109 METHODS AND COMPOSITIONS FOR NUCLEIC ACID ANALYSIS
The present invention is directed to methods, compositions and systems for analyzing sequence information while retaining structural and molecular context of...
2017/0159108 MICROBIAL POPULATION ANALYSIS
The present invention relates to a method of typing a microbiome for having a desirable or undesirable signature, comprising analyzing the composition of the...
2017/0159107 UNHEATED EXTRACTION OF GENOMIC DNA IN AN AUTOMATED LABORATORY SYSTEM
A method for analyzing genomic DNA includes introducing a plurality of samples comprising human cells into individual vessels in each of a plurality of...
2017/0159106 METHODS AND COMPOSITIONS FOR DETECTION OF SMALL RNAS
Currently, the circularization of small RNAs is broadly regarded as an obstacle in ligation-related assays and explicitly avoided while short lengths of linear...
2017/0159105 Enzyme Assays on a Droplet Actuator
The invention is directed to droplet actuator devices and assay methods. The invention includes assay methods of conducting an assay comprising combining a...
2017/0159104 METHODS FOR DETERMINING THE CONCENTRATION OF AN ANALYTE IN SOLUTION
Disclosed is a method for measuring the concentration of an analyte or analytes in a solution. Although the methods can be conducted using a number of...
2017/0159103 METHODS AND COMPOSITIONS FOR ASSAYING THE ACTIVITY OF ONE OR MORE LYSOSOMAL ENZYMES
Methods and liquid compositions for assaying the activity of one or more lysosomal enzymes in a sample are provided. In some embodiments, the assay is a...
2017/0159102 COMPOSITIONS AND METHOD FOR IDENTIFYING ENZYME AND TRANSPORT PROTEIN INHIBITORS
The invention is directed to compositions to screen for small molecule drugs that inhibit proteases, such as viral proteases, e.g., HIV proteases; and methods...
2017/0159101 DRUG-RESISTANT P97 ATPASE MUTATIONS
The invention relates to detection of drug insensitivity by detecting mutations in the p97 gene or the p97 gene product following treatment with a p97...
2017/0159100 WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION...
The invention provides probes with formula (I): ##STR00001## in which: X.sub.1.dbd.NH, O, or S; X.sub.2.dbd.O or S; SE is a labile group, which may be...
2017/0159099 PREPARING ANTIBODIES FROM CHO CELL CULTURES FOR CONJUGATION
The invention is based in part on the observation that a CHO cell oxidizing enzyme, particularly QSOX1, can survive a seemingly rigorous antibody purification...
2017/0159098 SALMONELLA DETECTION ARTICLES AND METHODS OF USE
An article for detecting Salmonella microorganisms is provided. The article comprises a highly selective nutrient medium and a plurality of indicator systems....
2017/0159097 CELL FREE TRANSLATION SYSTEM FOR COMPOUND SCREENING AND RELATED USES
The invention provides a cell-free system comprising not more than about 5% wheat germ extract for expressing proteins such as viral proteins and proteins...
2017/0159096 METHOD FOR FUSION EXPRESSION OF ION CHANNEL PROTEIN AND TRANSPORT PROTEIN AND PROTEIN FRAGMENT USED THEREFOR
The present invention provides a protein fragment for fusion expression of ion channel protein and transport protein. The protein fragment is a Bril protein...
2017/0159095 METHOD OF PRODUCTION OF RECOMBINANT GLYCOPROTEINS WITH INCREASED CIRCULATORY HALF-LIFE IN MAMMALIAN CELLS
Provided herein are methods and recombinant expression systems for the production of recombinant glycoproteins that have increased sialic acid content and...
2017/0159094 PRODUCTION OF GLYCOPROTEINS WITH MAMMALIAN-LIKE N-GLYCANS IN FILAMENTOUS FUNGI
The present disclosure relates to compositions and methods useful for the production of recombinant glycoproteins in filamentous fungal cells, such as...
2017/0159093 MODIFICATION OF RNA-RELATED ENZYMES FOR ENHANCED PRODUCTION
The present invention provides, among other things, methods and compositions for large-scale production of capped mRNA using SUMO-Guanylyl Transferase fusion...
2017/0159092 METHODS AND MATERIALS FOR PRODUCING 7-CARBON MONOMERS
This document describes biochemical pathways for producing 7-aminoheptanoic acid using a .beta.-ketoacyl synthase or a .beta.-ketothiolase to form an...
2017/0159091 BIOMASS FRACTIONATION PROCESS FOR BIOPRODUCTS
A fractionation process for producing value-added products from a lignocellulosic biomass, comprises: a) mechanically refining the lignocellulosic biomass...
2017/0159090 Compositions for Producing Glucose Syrups
The present invention relates to a method of making glucose syrup from liquefied starch comprising, (a) contacting the liquefied starch with a glucoamylase, a...
2017/0159089 METHOD OF PRODUCING GLUCOSE FROM A CELLULOSIC BIOMASS USING ENZYMATIC HYDROLYSIS
The present invention relates to a method of producing glucose from a cellulosic biomass using enzymatic hydrolysis. The present invention also relates to a...
2017/0159088 PROCESSES FOR THE PREPARATION OF (R)-2-(7-(4-CYCLOPENTYL-3-(TRIFLUOROMETHYL)BENZYLOXY)-1,2,3,4-TETRAHYDROC- ...
The present invention relates to processes and intermediates useful in the preparation of ...
2017/0159087 Methods of Using Natural and Engineered Organisms to Produce Small Molecules for Industrial Application
Aspects of the invention relate to methods of producing small molecules for industrial application using natural organisms and engineered organisms.
2017/0159086 METHODS AND MATERIALS FOR PRODUCING 5 AND 7-CARBON MONOMERS
This document describes biochemical pathways for biosynthesizing a 3-oxo-7-hydroxyheptanoyl-CoA intermediate using a .beta.-ketothiolase, and enzymatically...
2017/0159085 MICROORGANISMS FOR PRODUCING DIAMINE AND PROCESS FOR PRODUCING DIAMINE USING THEM
The present invention relates to a microorganism for producing diamine, in which activity of a protein having an amino acid sequence of SEQ ID NO: 6 or an...
2017/0159084 Modified Cyanobacteria
Provided is a cyanobacterium with improved productivity of fatty acid. A method for producing a modified cyanobacterium, comprising causing loss of functions...
2017/0159083 ARGININE SUPPLEMENTATION TO IMPROVE EFFICIENCY IN GAS FERMENTING ACETOGENS
The invention provides methods for improving efficiency of fermentation by arginine supplementation, and genetically modified bacterium for use therefor. More...
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