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Patent # Description
2017/0158678 SUBSTITUTED PYRIDINE DERIVATIVES USEFUL AS C-FMS KINASE INHIBITORS
The present invention is directed to substituted pyridine derivatives, pharmaceutical compositions containing said derivatives and the use of said derivatives...
2017/0158677 SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification; the compounds of the invention...
2017/0158676 PROCESSES FOR PRODUCING CYCLOALKYLCARBOXAMIDO-PYRIDINE BENZOIC ACIDS
The present invention relates to a process of providing the 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) ...
2017/0158675 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO
This document discloses molecules having the following formula ("Formula One"): ##STR00001## and processes associated therewith.
2017/0158674 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO
This document discloses molecules having the following formula ("Formula One"): ##STR00001## and processes associated therewith.
2017/0158673 QUINAZOLINONE DERIVATIVES AS PARP INHIBITORS
The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of...
2017/0158672 Benzocyanine Compounds
Compounds useful as labels with properties comparable to known fluorescent compounds. The compounds are conjugated to proteins and nucleic acids for biological...
2017/0158671 PYRIMIDINE COMPOSITIONS, ULTRA PURE COMPOSITIONS AND SALTS THEREOF, METHODS OF MAKING THE SAME, AND METHODS OF...
The present application relates to ultra-pure compositions containing N.sup.4-(cyclopropylmethyl)-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimi- ...
2017/0158670 PYRIDINEAMINE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS
The present disclosure describes pyridineamine compounds, as well as their compositions and methods of use. The compounds inhibit the activity of the Pim...
2017/0158669 INDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF
Provided herein are compounds of the formulas (I) and (II): ##STR00001## as well as pharmaceutically acceptable salts thereof, wherein the substituents are as...
2017/0158668 2-(3-PYRIDINYL)-1H-BENZIMIDAZOLE DERIVATIVE COMPOUND AND MEDICINE CONTAINING SAME
Provided is a compound represented by general formula (1) or a salt thereof as well as a medicine containing the compound or the salt. ##STR00001## In the...
2017/0158667 2-(2,4-DIFLUOROPHENYL)-1,1-DIFLUORO-1-(5-SUBSTITUTED-PYRIDIN-2-YL)-3-(1H-T- ETRAZOL-1-YL)PROPAN-2-OLS AND...
Provided herein are 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1H-- tetrazol-1-yl)propan-2-ols and ...
2017/0158666 APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases...
2017/0158665 METHOD FOR PREPARING THE ANHYDROUS CRYSTALLINE FORM OF ISONIAZID-DERIVED HYDRAZONE, THUS PRODUCED CRISTALLINE...
The present invention relates to the method for preparing the anhydrous crystalline form of isoniazid-derived hydrazone (8-hydroxyquinoline-2-carboxaldehyde...
2017/0158664 HISTONE DEMETHYLASE INHIBITORS
Provided herein are substituted pyrazolylpyridine, pyrazolylpyridazine, and pyrazolylpyrimidine derivative compounds and pharmaceutical compositions comprising...
2017/0158663 HALOGEN-SUBSTITUTED HETEROCYCLIC COMPOUND SALT
The invention provides a novel .alpha.-halogen-substituted thiophene compound salt that has a potent LPA receptor antagonistic action and is useful as a...
2017/0158662 Process for the Preparation of 4-Amino-1-((1S,4R,5S)-2-Fluoro-4,5-Dihydroxy-3-Hydroxymethyl-Cyclopent-2-- ...
Processes for the preparation of 4-amino-1-((1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-hydroxymethyl-cyclopent-2-- enyl)-1H-pyrimidin-2-one (13, RX-3117) and its...
2017/0158661 A METHOD OF PREPARING A LIQUIRITIGENIN PRECURSOR
[Problem] To provide a process suitable for mass-producing of iso-liquiritigenin. [Solution] A process for preparing iso-liquiritigenin, which comprises steps...
2017/0158660 CATALYST FOR SYNTHESIZING THEAFLAVINS AND METHOD FOR SYNTHESIZING THEAFLAVINS
The objective/problem addressed by the present invention is to provide a novel technique pertaining to theaflavins synthesis. The present invention pertains...
2017/0158659 CO-CRYSTAL OF DAPAGLIFLOZIN WITH CITRIC ACID
The present invention relates to a dapagliflozin-citric acid co-crystal, processes for its preparation, and its use for the treatment of type 2 diabetes...
2017/0158658 METHOD OF PRODUCING BERAPROST
An improved method is described for making single isomers of synthetic benzoprostacyclin analogue compounds, in particular the pharmacologically active 314-d...
2017/0158657 TERTIARY AMINES FOR USE IN THE TREATMENT OF CARDIAC DISORDERS
The present invention relates to tertiary amines of formula (I) for use in therapy, particularly for use in treating cardiovascular disorders. The compounds...
2017/0158656 CONVERSION OF FRUCTOSE-CONTAINING FEEDSTOCKS TO HMF-CONTAINING PRODUCT
The present invention relates generally to processes for converting fructose-containing feedstocks to a product comprising 5-(hydroxymethyl)furfural (HMF) and...
2017/0158655 CATALYSTS CONTAINING SPECIFIC TITANIUM POLYMORPHIC FORMS
A catalyst composition which comprises titanium, wherein part of the titanium is present as a titanium dioxide phase and at least some of the titanium dioxide...
2017/0158654 METHOD FOR THE PRODUCTION OF ETHYLENE OXIDE
A method for the production of ethylene oxide wherein the partial pressure of water vapor at the inlet of the reactor is at least about 8 kPa using a high...
2017/0158653 CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS
The present invention includes crystalline forms of 2-amino-3-methyl-N-(2-morpholinoethyl)-pentanamide disulfate and crystalline forms of...
2017/0158652 PROCESS FOR PREPARING SUBSTITUTED 5-FLUORO-1H-PYRAZOLOPYRIDINES
The present application relates to a novel and efficient process for preparing novel substituted 5-fluoro-1H-pyrazolopyridines of the formula (VI) ...
2017/0158651 SMALL MOLECULE COMPOUND AND SYNTHESIZING METHOD AND USES THEREOF
Provided is a small molecule compound as represented by structural formula (I). The product of the present invention in various concentrations and dosages can...
2017/0158650 DEUTERATED 1-PIPERAZINO-3-PHENYL INDANES FOR TREATMENT OF SCHIZOPHRENIA
The present invention relates to deuterated 1-piperazino-3-phenyl-indanes and salts thereof with activity at dopamine receptors D.sub.1 and D.sub.2 as well as...
2017/0158649 SYNTHESIS OF CHIRALLY PURIFIED SUBSTITUTED BENZOTHIAZOLE DIAMINES
Methods for preparing chirally purified substituted 4,5,6,7-tetrahydro-benzotiazole diamines such as, for example, ...
2017/0158648 SYNTHESIS OF AMINE SUBSTITUTED 4,5,6,7-TETRAHYDROBENZOTHIAZOLE COMPOUNDS
The present invention is related to an improved process for the preparation of amino-substituted 4,5,6,7-tetrahydrobenzothiazole compounds of formula I, such...
2017/0158647 MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS
The present application provides for a compound of Formula IV, ##STR00001## or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions...
2017/0158646 SUBSTITUTED [1,2,4]TRIAZOLE COMPOUNDS
1. The present invention relates to compounds of the formula I ##STR00001## wherein the variables are defined in the description and claims, their preparation...
2017/0158645 AMORPHOUS FORM AND NEW CRYSTALLINE FORMS OF MACITENTAN
The present invention relates to the amorphous form of macitentan and to new crystalline forms thereof. The invention also relates to processes for the...
2017/0158644 2-Amino-5-keto-pyrimidine derivatives and the use thereof for controlling undesired plant growth
What are described are compounds of the general formula (I) and agrochemically acceptable salts thereof ##STR00001## and the use thereof in the crop protection...
2017/0158643 PROCESS FOR PREPARATION OF ANDROGEN RECEPTOR ANTAGONIST
The present invention provides an isopropanol solvate of enzalutamide. The present invention also provides a process for the preparation of androgen receptor...
2017/0158642 COMPOSITION FOR INDUCING CELL REPROGRAMMING
The present invention relates to a composition for inducing cell reprogramming. The indazole derivative compound contained in the composition of the present...
2017/0158641 NOVEL FORM OF MEFENPYR-DIETHYL, A PROCESS FOR ITS PREPARATION AND USE OF THE SAME
A crystalline form of mefenpyr-diethyl of formula (I), the crystal preparation process, the analyses of the crystal through various analytical methods and...
2017/0158640 Ring Closing Metathesis Approach To Produce Precursors Of Nylon 11, 12, And 13 From Oleic Acid
Provided herein is a method of producing C11, C12, and C13 nylon precursors from oleic acid or esters of oleic acid, the method involving amide formation,...
2017/0158639 METHOD FOR PRODUCING 4,4,7-TRIFLUORO-1,2,3,4-TATRAHYDRO-5H-1-BENZAZEPINE COMPOUND AND INTERMEDIATE USED IN THE...
The present invention provides a method for producing a 4,4,7-trifluoro-1,2,3,4-tetrahydro-5H-1-benzazepine compound which has an superior agonistic activity...
2017/0158638 PIPERIDINONE HERBICIDES
Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof: ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.2A,...
2017/0158637 Synthetic Processes of Carprofen
Methods and intermediates for the synthesis of carprofen and its derivatives starting from cyclohexanone are disclosed.
2017/0158636 FUNCTIONALISED AND SUBSTITUTED CARBAZOLES AS ANTI-CANCER AGENTS
The present invention relates to anti-tropomyosin compounds, processes for their preparation, and methods for treating or preventing a disease or disorder,...
2017/0158635 SYSTEM AND METHOD FOR ORGANIC SOLVENT PURIFICATION
An organic solvent purification system that separates an organic solvent having a boiling point of more than 100.degree. C. at 1 atm, such as ...
2017/0158634 CARBOXAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B
Inhibitors of HBV replication of formula (I) ##STR00001## including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X, R.sup.1 to...
2017/0158633 CYCLOPROPYLAMINES AS LSD1 INHIBITORS
The present invention is directed to cyclopropylamine derivatives which are LSD1 inhibitors useful in the treatment of diseases such as cancer.
2017/0158632 COMPLEXES OF DIPHENYL SELENOXIDES, USE THEREOF AND CATALYSIS METHODS
Novel complexes of diphenyl selenoxides and also use thereof and methods in which the complexes are used.
2017/0158631 METHOD FOR PREPARING METHYL MERCAPTAN
The present invention relates to a method for preparing methyl mercaptan, in batches or continuously, preferably continuously, said method including at least...
2017/0158630 Beta-Mercaptoethanol Synthesis
A process includes reacting, in a reactor having a fixed bed containing a solid catalyst which contains a heterogeneous ion exchange resin, hydrogen sulfide...
2017/0158629 Herbicidally Active Arylcarboxylic Acid Amides
Benzamides of the general formula (I) are described as herbicides. ##STR00001## In this formula (I), X, Z and R are radicals such as alkyl and cycloalkyl. Q is a...
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