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Patent # Description
2017/0157263 LHRH-Platinum Conjugates For Treating Reproductive Cancers
The conjugation of luteinizing hormone-releasing hormone (LHRH) with activated cisplatin using a malonate linker gives rise to a new Platinum-LHRH conjugate...
2017/0157262 CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS
A conjugate of a potent cytotoxic agent with a cell-surface receptor binding molecule having a formula (I), wherein T, L, m, n, Y, R.sup.1, R.sup.2, R.sup.3,...
2017/0157261 GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE
Disclosed are conjugates, compositions, and methods that include or use one or more gold(III) porphyrin complexes. Preferred conjugates are gold(III)...
2017/0157260 Glycosylated Polypeptide and Drug Composition Containing said Polypeptide
[Problem] To provide a glycosylated polypeptide having an affinity to somatostatin receptors, and, compared to somatostatins, having improved in-blood...
2017/0157259 FACTOR VIII POLYMER CONJUGATES
The invention is a proteinaceous construct comprising a Factor VIII molecule which is conjugated to a water-soluble polymer via carbohydrate moieties of Factor...
2017/0157258 POVIDONE-IODINE TOPICAL COMPOSITION
The present invention relates to a topical pharmaceutical composition comprising povidone-iodine, a tertiary amide, surfactant and coconut oil, useful for...
2017/0157257 PROCESS FOR PRODUCING COMPOSITION OF EMULSION PREPARATION TYPE
preparing a composition, which forms a coating film having excellent properties after application though the formulation is the same characterized in that 1) a...
2017/0157256 Viscosity-Reducing Excipient Compounds for Protein Formulations
The invention encompasses formulations and methods for the production thereof that permit the delivery of concentrated protein solutions. The inventive methods...
2017/0157255 COMPOSITIONS AND METHODS FOR REDUCING OVERDOSE
Drug delivery formulations, uses thereof and methods of making same are provided in order to reduce the potential for abuse, misuse or improper administration...
2017/0157254 COMBINATION OF AN OXIDANT, A PHOTOSENSITIZER AND A WOUND HEALING AGENT FOR ORAL DISINFECTION AND TREATMENT OF...
The present document describes methods of use of photo activated compositions for oral disinfection and/or treatments which comprise at least one oxidant, at...
2017/0157253 TREATMENT OF CANCER OR TUMOR INDUCED BY THE RELEASE OF HEAT GENERATED BY VARIOUS CHAINS OF MAGNETOSOMES...
A method for the treatment of tumor(s), tumor cell(s), cancer(s) in a subject by the generation of heat. The latter is produced by chains of magnetosomes...
2017/0157252 DRUG CARRIER AND METHOD OF USING THE SAME
A drug carrier and a method of using the same are provided, wherein the drug carrier includes a base made of a carbon fiber which is magnetic and has a first...
2017/0157251 Bi-Specific Monovalent Diabodies That are Capable of Binding CD19 and CD3, and Uses Thereof
The present invention is directed to a combination therapy involving the administration of: (1) a bi-specific molecule capable of specifically binding to CD19...
2017/0157250 ANTIBODIES BINDING AXL
The present disclosure relates to anti-AXL antibodies, immunoconjugates, compositions and method of treatment of cancer with such anti-AXL antibodies,...
2017/0157249 USES AND COMPOSITIONS FOR TREATMENT OF RHEUMATOID ARTHRITIS
The invention provides methods, uses and compositions for the treatment of rheumatoid arthritis. The invention describes methods and uses for treating...
2017/0157248 ANTI-INFLAMMATORY FACTOR RETENTATE, METHOD OF ISOLATION, AND USE
The invention relates to an anti-inflammatory factor isolated from milk, methods of purifying the anti-inflammatory factor through ultrafiltration and...
2017/0157247 Method of Treating Lupus By Administering An Anti-IL-12 Antibody
An anti-IL-12 antibody that binds to a portion of the IL-12 protein corresponding to at least one amino acid residue selected from the group consisting of...
2017/0157246 BIOMARKERS USEFUL IN THE TREATMENT OF IL-23A RELATED DISEASES
This invention generally relates to biomarkers useful in the treatment of IL-23 related diseases, in particular inflammatory diseases such as psoriasis. The...
2017/0157245 TREATMENT OF GASTRIC CANCER
The present invention relates to VEGF-binding agents, DLL4-binding agents, VEGF/DLL4 bispecific binding agents, and methods of using the agents for treating...
2017/0157244 VACCINATION RESPONSE FOR IMMUNODEFICIENCY DISORDERS OR HIGH CORTISOL
A method of improving a human's response to vaccination with a vaccine enhancement food. This food contains at least transfer factor and lactic acid generating...
2017/0157243 MANF as a Regulator of Immune System Function
Methods and compositions for enhancing an immunological response by administering an immunogenic composition comprising an effective amount of a MANF family...
2017/0157242 SYNERGISTIC NUTRITIONAL COMPOSITIONS AND USES THEREOF
Provided are nutritional compositions comprising a combination of a probiotic, dietary butyrate and/or a component for stimulating butyrate production in the...
2017/0157241 COMPOSITIONS AND METHODS OF ENHANCING IMMUNOGENICITY OF POLYSACCHARIDE PROTEIN CONJUGATES
The present invention provides compositions and methods for enhancing immunogenicity of polysaccharide antigens. Immunogenic compositions and vaccines...
2017/0157240 COMPOSITION OF ALLERGEN EXTRACTS HAVING REDUCED TOXICITY AND METHOD OF PRODUCTION THEREOF
The present invention concerns pollen allergen extracts, in particular ragweed (Ambrosia) pollen allergen extracts, containing reduced amounts of...
2017/0157239 LIVE BACTERIAL VACCINES RESISTANT TO CARBON DIOXIDE (CO2), ACIDIC PH AND/OR OSMOLARITY FOR VIRAL INFECTION...
Gram-negative bacterial mutants resistant to one or more stress conditions, including CO.sub.2, acid pH, and high osmolarity, and more particularly to...
2017/0157238 HPV VACCINE FORMULATIONS COMPRISING ALUMINUM ADJUVANT AND METHODS OF PRODUCING SAME
The invention provides human papillomavirus (HPV) antigen formulations which show increased antigen stability. More specifically, the invention provides stable...
2017/0157237 METHOD FOR THE PRODUCTION OF RECOMBINANT VIRUS, DNA CONSTRUCTS, RECOMBINANT VIRUS AND VACCINE COMPOSITIONS
The purpose of the present invention is the production of recombinant virus through the cloning and expression of sequences of coding nucleotides of the whole...
2017/0157236 VACCINE AGAINST PORCINE CIRCO VIRUS TYPE 2
The present invention pertains to a vaccine comprising a non-replicating immunogen of porcine circo virus type 2 for use in prophylactically treating an animal...
2017/0157235 METHOD FOR PRODUCING AND VACCINE COMPOSITION OF NEISSERIA MENINGITIDIS SEROGROUPS A, C, Y, AND W-135...
A multivalent vaccine composition, a method of producing the multivalent vaccine composition, and an apparatus containing the multivalent vaccine composition....
2017/0157234 Vaccines and Compositions Against Streptococcus Pneumoniae
Streptococcus pneumoniae is a major health concern, especially in very young, elderly, or immunocompromised patients. The present disclosure provides, inter...
2017/0157233 Immunogenic Compositions
This disclosure relates to immunogenic compositions comprising an isolated immunogenic S. pneumoniae PcpA polypeptide, at least one additional antigen (such as...
2017/0157232 Immunological Compositions Containing Attenuated Histophilus somni
This disclosure provides attenuated Histophilus somni strains, compositions comprising same, and methods of production and use thereof. The attenuated strains...
2017/0157231 Therapeutic Cancer Vaccine
The present invention relates to vaccine(s) comprising cancer cells expressing antigen(s), excipients, optionally adjuvant wherein the said antigen(s) is...
2017/0157230 MODIFIED NATURAL KILLER CELLS AND NATURAL KILLER CELL LINES HAVING INCREASED CYTOTOXICITY
NK cells and NK cell lines are modified to increase cytotoxicity, wherein the cells and compositions thereof have a use in the treatment of cancer. Production...
2017/0157229 Combination Therapy
The invention relates to producing humoral response to P2X7 receptors in individuals having cancer, and to minimising the progression of cancer in said...
2017/0157228 Immunogenic Polypeptide Composed of HLA-B7 Restricted Tumor Antigen-Derived Optimized Cryptic Peptides, and...
The invention pertains to an optimized chimeric polypeptide for use in HLA-337 cancer patients, which comprises four optimized peptides derived from cryptic...
2017/0157227 Mucin-Associated Surface Protein as a Vaccine Against Chagas Disease
Use of synthetic peptides derived from Trypanosoma cruzi antigens and their use in vaccination against trypomastigote infection and Chagas disease. T. cruzi...
2017/0157226 PEPTIDE FOR VACCINE
The present invention relates to compositions comprising peptides for preventing or treating allergy to house dust mites, and in particular to optimal...
2017/0157225 COMPLETE GENOME SEQUENCE OF THE METHANOGEN METHANOBREVIBACTER RUMINANTIUM
The present invention includes the complete genome sequence for the methanogen, Methanobrevibacter ruminantium, including polynucleotides which encode M....
2017/0157224 PREPARATION AND COMPOSITION OF INTER-ALPHA INHIBITOR PROTEINS FROM BLOOD
The present invention generally provides processes for purification of Inter-alpha inhibitor proteins (I.alpha.Ip) and compositions thereof from blood.
2017/0157223 PROHEMOSTATIC PROTEINS FOR THE TREATMENT OF BLEEDING
This disclosure relates to recombinant FXa polypeptides that can be used as antidotes to completely or partially reverse an anti-coagulant effect of a...
2017/0157222 THROMBIN MICROCAPSULES, PREPARATION AND USES THEREOF
Provided are spray-dried thrombin powders comprising microcapsules, methods of preparation and uses thereof.
2017/0157221 METHOD FOR TREATING PERVASIVE DEVELOPMENT DISORDERS
A method of utilizing the chymotrypsin level of an individual as a measure of the success of secretin, other neuropeptides, and peptides or digestive enzyme...
2017/0157220 Variant, Recombinant Beta-Glucocerebrosidase Proteins With Increased Stability And Increased Retained Catalytic...
Described herein are variant, recombinant .beta.-glucocerebrosidase proteins characterized as having increased stability relative to recombinant wild-type...
2017/0157219 METHODS OF TREATING ZIKA VIRUS, MERS-COV, CHIKUNGUNYA, VENEZUELAN EQUINE ENCEPHALITUS, AND RHINOVIRUS IN...
Viral infections in mammals can be treated and prophylactically prevented by systemic administration of ranpirnase and three other ribonucleases that are...
2017/0157218 METHODS OF TREATING FRAGILE X SYNDROME AND RELATED DISORDERS
Disclosed herein are novel methodologies of treating fragile X syndrome and related disorders by inhibiting mG1u.sub.5-relevant signaling pathways via the...
2017/0157217 USE OF ENDOSTATIN PEPTIDES FOR THE TREATMENT OF FIBROSIS
C-terminal endostatin polypeptides are disclosed herein. Polynucleotides encoding these polypeptide, host cells transformed with the polynucleotides, and...
2017/0157216 COMPOSITIONS AND METHODS FOR TREATMENT OF PEDIATRIC PAIN
Disclosed are methods of treating pain in a mammal, which may include the step of administering human growth hormone to a mammal in need thereof. The pain...
2017/0157214 ANTI-INFLAMMATORY PROTEINS AND METHODS OF PREPARATION AND USE THEREOF
The present disclosure relates to anti-inflammatory proteins, their uses, methods of preparation and methods of their detection. In particular, the invention...
2017/0157213 EFFICIENT SYSTEMIC TREATMENT OF DYSTROPHIC MUSCLE PATHOLOGIES
A composition comprising a gene therapy product for use in the treatment of a dystrophic disease in a subject, advantageously in humans, wherein:--the gene...
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