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Patent # Description
2017/0157162 NUCLEOBASE ANALOGUE DERIVATIVES AND THEIR APPLICATIONS
Disclosed herein are derivatives of nucleobase analogues. The disclosed compounds have a nucleobase moiety and an omega-3 polyunsaturated fatty acid moiety,...
2017/0157161 Anti-Cancer Therapies
Methods for the treatment of cancer are described. In particular, methods for treatment of cancer comprising administration of glufosfamide alone or in...
2017/0157160 METHODS AND FORMULATIONS FOR TREATING SIALIC ACID DEFICIENCIES
The present invention relates to compositions and methods for treating sialic acid deficiencies comprising extended release formulations.
2017/0157159 COMBINATION TREATMENT OF ACUTE MYELOID LEUKEMIA AND MYELODYSPLASTIC SYNDROME I
The present invention relates to the use of Volasertib or a salt thereof or the hydrate thereof in combination with Decitabine or a salt thereof or the hydrate...
2017/0157158 COMBINATION TREATMENT OF ACUTE MYELOID LEUKEMIA AND MYELODYSPLASTIC SYNDROME II
The present invention relates to the use of Volasertib or a salt thereof or the hydrate thereof in combination with Azacitidine or a salt thereof or the...
2017/0157157 METHOD FOR IMPROVING VENTILATORY EFFICIENCY
A method for improving ventilatory efficiency, comprising the administration of a pentose is disclosed. The most preferred pentose is D-ribose, to be...
2017/0157156 TRADITIONAL CHINESE MEDICINE COMPOSITION, AND PREPARATION AND APPLICATION THEREOF
A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof,...
2017/0157155 METHOD OF TREATMENT OF NASOPHARYNGEAL CANCER
The present invention provides a method of treating nasopharyngeal cancer with a proteasome inhibitor of formula (7). The invention also provides a method of...
2017/0157154 CELL MOBILIZATION AGENT CONTAINING LYSOPHOSPHOLIPID WITH RETINOIC ACID INTRODUCED
The invention provides a cell mobilizing agent capable of efficiently and continuously accumulating cells involved in tissue repair. In particular, the cell...
2017/0157153 COMPOSITIONS FOR ORAL ADMINISTRATION OF ZOLEDRONIC ACID OR RELATED COMPOUNDS FOR TREATING COMPLEX REGIONAL PAIN...
Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,...
2017/0157152 OSTEOCLAST INHIBITORS FOR JOINT CONDITIONS
Oral dosage forms of osteoclast inhibitors, such as neridronic acid and zoledronic acid, in an acid or a salt form, can be used to treat or alleviate pain or...
2017/0157151 Broad Spectrum Antiviral and Methods of Use
A method for the prevention or treatment of Influenza virus infection or Adenovirus infection by administering an effective amount of a compound of Formula...
2017/0157150 ORAL DOSAGE FORM COMPRISING TRI-SUBSTITUTED GLYCEROL COMPOUNDS
The present invention relates to pharmaceutical solid dosage forms for oral administration comprising a tri-substituted glycerol compound or a pharmaceutically...
2017/0157149 COMPOSITIONS AND METHODS FOR DISEASE TREATMENT USING NANOPARTICLE DELIVERED COMPOUNDS
Provided herein are compositions and methods for the treatment of diseases, such as hyperproliferative diseases, employing compounds formulated for...
2017/0157148 TREATMENT OF PROSTATE CANCER
Described herein are compounds, methods of making such compounds, pharmaceutical compositions, and medicaments comprising such compounds, and methods of using...
2017/0157147 GLUCOCORTICOID-LOADED NANOPARTICLES FOR PREVENTION OF CORNEAL ALLOGRAFT REJECTION AND NEOVASCULARIZATION
Particles encapsulating a glucocorticoid such as dexamethasone sodium phosphate (DSP) into a matrix such as biodegradable poly(lactic-coglycolic acid) (PLGA)...
2017/0157146 CO-MICRONISATION PRODUCT COMPRISING ULIPRISTAL ACETATE
The subject of the present invention is a co-micronization product comprising an active ingredient selected from the group consisting of ulipristal acetate, a...
2017/0157145 SUBSTANCE INDUCING EXPRESSION OF PARKIN POLYPEPTIDE AND USE THEREOF
A method of inducing Parkin expression; inhibiting oxidative stress; and inhibiting cell death of cells by administering deferasirox, hydrocortisone,...
2017/0157144 PREPARATION METHOD FOR ANTITHYROID OINTMENT FOR EXTERNAL APPLICATION
A preparation method for an antithyroid ointment for external application is provided. The ointment includes the following components by mass percentage:...
2017/0157143 NORPREGNANE DERIVATIVES FOR THE RISK REDUCTION OF BREAST CANCER
In one embodiment, the application discloses a method for the prophylaxis or the treatment of a pre-cancerous lesion, including atypical intraductal breast...
2017/0157142 USE OF TESTOSTERONE AND A 5-HT1A AGONIST IN THE TREATMENT OF SEXUAL DYSFUNCTION
The invention relates to the field of male and/or female sexual dysfunction. The invention specifically relates to the use of testosterone and a 5-HT1A agonist.
2017/0157141 METHOD OF TREATING LEUKEMIA USING PHARMACEUTICAL FORMULATION CONTAINING THIENOTRIAZOLODIAZEPINE COMPOUNDS
A method of treating leukemia in a mammal by administering a solid dispersion comprising an amorphous thienotriazolodiazepine compound of the Formula (1)...
2017/0157140 Methods Of Improving The Pharmacokinetics Of Doxepin
Methods of improving the pharmacokinetics of doxepin in a patient.
2017/0157139 MUSCARINIC M1 RECEPTOR AGONISTS
This invention relates to compounds that are agonists of the muscarinic M1 receptor and which are useful in the treatment of muscarinic M1 receptor mediated...
2017/0157138 COMBINATION OF BRIMONIDINE AND TIMOLOL FOR TOPICAL OPHTHALMIC USE
Disclosed are pharmaceutical compositions comprising brimonidine and timolol for topical ophthalmic delivery and a method of treatment comprising administering...
2017/0157137 2,7-DIAZASPIRO[3.5]NONANE COMPOUNDS
The present invention relates to a compound of formula (I) or a stereoisomer, enantiomer, racemic, or tautomer thereof, Formula (I), wherein R.sup.1, R.sup.3,...
2017/0157136 NOVEL COMPOUNDS
The invention is directed to methods of treatment using compounds of formula (I): ##STR00001## and salts thereof. The compounds of the invention are inhibitors...
2017/0157135 FUNCTIONALISED AND SUBSTITUTED INDOLES AS ANTI-CANCER AGENTS
The present invention relates to anti-tropomyosin compounds, processes for their preparation, and methods for treating or preventing a proliferative disease,...
2017/0157134 COMBINATION THERAPY
A pharmaceutical combination comprising (a) a compound of formula (I), ##STR00001## or pharmaceutically acceptable salts thereof; and (b) one or more at least...
2017/0157133 NOVEL PYRIDAZONES AND TRIAZINONES FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION
The invention provides novel compounds having the general formula: ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, X and a are as described in the description...
2017/0157132 METHODS OF TREATMENT OF MALIGNANCIES
Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation or IDH2 mutation.
2017/0157131 ANTITUMOR EFFECT POTENTIATOR AND ANTITUMOR AGENT
The present invention provides an antitumor effect potentiator for enhancing antitumor activity of an antitumor agent comprising tegafur in a therapeutically...
2017/0157130 TREATMENT OF MYELODYSPLASTIC SYNDROME
The present invention relates to the use of Volasertib or a pharmaceutically acceptable salt thereof or the hydrate thereof for treating myelodysplastic...
2017/0157129 LOW DOSE PHARMACEUTICAL COMPOSITION
Present invention relates to a low dose pharmaceutical composition, preferably oral composition comprising therapeutically effective amount of...
2017/0157128 METHOD FOR TREATING ERECTILE DYSFUNCTION
Erectile dysfunction in a male human patient is ameliorated by oral administration to the patient of prednisone followed by administration of sildenafil,...
2017/0157127 METHODS OF FACILITATING CELL SURVIVAL USING NEUROTROPHIN MIMETICS
Methods and compounds for treating neurodegenerative and other disorders. Included is the administering to a subject in need thereof an effective amount of a...
2017/0157126 USES OF PYRIMIDO-PYRIDAZINONES TO TREAT CANCER
Disclosed are methods of treating cancer, which include administering a therapeutically effective amount of a compound of Formula (I), or a pharmaceutically...
2017/0157125 METHOD OF TREATING HYPERTENSION
Disclosed herein are compositions and methods for the treatment of pulmonary hypertension, including pulmonary arterial hypertension. The methods include...
2017/0157124 COMBINATIONS OF AKT INHIBITOR COMPOUNDS AND CHEMOTHERAPEUTIC AGENTS, AND METHODS OF USE
The invention provides combinations comprising a) compound of formula I: ##STR00001## or a pharmaceutically acceptable salt thereof wherein R.sup.1, R.sup.2, ...
2017/0157123 CYCLING THERAPY USING 3-(5-AMINO-2-METHYL-4-OXO-4H-QUINAZOLIN-3-YL)-PIPERIDINE-2,6-DIONE
Provided herein are methods of treating, preventing and/or managing cancer, including lymphoma, which comprise administering to a patient ...
2017/0157122 FUNGICIDAL AGENT
The invention relates to a novel fungicidal agent in the form of a salt associate having the structural formula shown. The agent can be used for treating...
2017/0157121 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 BETA INHIBITORS
The present invention relates to the 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta (GSK-3.beta.) inhibitors and to their use in the...
2017/0157120 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR
Compounds active on protein kinases are described, as well as methods of making and using such compounds to treat diseases and conditions associated with...
2017/0157119 SOLID ORAL FILM DOSAGE FORMS AND METHODS FOR MAKING SAME
Oral film dosage forms that provide improved solubilization and stabilization of an active ingredient in particle form include at least one primary...
2017/0157118 2-AMINOPYRAZINE DERIVATIVES AS CSF-1 R KINASE INHIBITORS
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt, N-oxide, hydrate or solvate thereof: wherein: ring A, R.sup.1,...
2017/0157117 ARIPIPRAZOLE FORMULATIONS HAVING INCREASED INJECTION SPEEDS
The present invention relates to pharmaceutical compositions comprising a compound of Formula (I) that are useful for the intramuscular delivery of ...
2017/0157116 METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE
Abuse-resistant opioid compounds, drug delivery systems, pharmaceutical compositions comprising an opioid covalently bound to a chemical moiety are provided....
2017/0157115 PHARMACEUTICAL FORMULATION CONTAINING OPIOID AGONIST, OPIOID ANTAGONIST AND GELLING AGENT
Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of an opioid analgesic, an opioid antagonist and one or...
2017/0157114 ABUSE RESISTANT OPIOID TRANSDERMAL DELIVERY DEVICE CONTAINING OPIOID ANTAGONIST MICROSPHERES
The present invention provides abuse-resistant transdermal delivery devices containing an opioid agonist intended for analgesic purposes in pain patients.
2017/0157113 4-(8-METHOXY-1-((1-METHOXYPROPAN-2-YL)-2-(TETRAHYDRO-2H-PYRAN-4-YL)-1 ...
Novel quinoline compounds pharmaceutical compositions containing such compounds and their use in therapy.
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