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Patent # Description
2017/0165384 EX VIVO ANTIMICROBIAL DEVICES AND METHODS
A method and device for destroying and inhibiting exposure to microbes and infection includes a first element and a second element, and a power source. At...
2017/0165383 VARIABLE DOMAINS OF CAMELID HEAVY-CHAIN ANTIBODIES DIRECTED AGAINST GLIAL FIBRILLARY ACIDIC PROTEINS
The present invention relates to the use of variable domains of camelid heavy-chain antibodies (VHH domains) directed against an intracellular target and...
2017/0165382 NANOCARRIERS FOR CANCER TREATMENT
The present invention provides conjugates containing metal binding ligands, as well as nanocarriers prepared from the conjugates.
2017/0165381 Combination of Deuterated Levodopa With Carbidopa and Opicapone For The Treatment of Parkinson's Disease
The present invention relates to new combinations of treatments for abnormal dopamine deficiency disorders, and related conditions, comprising deuterated...
2017/0165380 Nanosensor Compositions and Methods of use Thereof
Disclosed are compositions comprising a plastic polymer core, a shell surrounding the plastic polymer core, a ligand comprising a binding moiety, an enzyme...
2017/0165379 Endoscopic Mucosal Lift Kit
Method and Product; For use in the human digestive tract for endoscopic submucosal injection, as an aid in identifying the extent and borders of flat mucosal...
2017/0165378 COMPOSITION FOR TREATING CANCEROUS CELLS AND A METHOD THEREFOR
A composition for treating cancerous cells in a subject having an immune system includes a virus in the Yatapoxvirus genus having at least one mutation. In one...
2017/0165377 ISOLATION OF NOVEL AAV'S AND USES THEREOF
The invention in some aspects relates to isolated nucleic acids, compositions, and kits useful for identifying adeno-associated viruses in cells. In some...
2017/0165376 APTAMERS FOR TUMOR INITIATING CELLS
Aptamers consisting of a single stranded nucleic acids having 100 nucleotides or less that specifically binds to tumor initiating cancer cells are described....
2017/0165375 ANTIBIOTIC PROTOCELLS AND RELATED PHARMACEUTICAL FORMULATIONS AND METHODS OF TREATMENT
The invention provides novel antibiotic protocells comprising mesoporous nanoparticles encapsulated within a lipid bi- or multilayer. The nanoparticles have...
2017/0165374 COMPOSITIONS AND METHODS FOR TREATING BACTERIAL INFECTIONS
Provided herein are pharmaceutical compositions comprising an antibiotic encapsulated in liposomes. The lipid membrane component of the liposomes, or portion...
2017/0165373 BCMA ANTIGEN BINDING PROTEINS
The present invention relates to BCMA (B-Cell Maturation Antigen) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen...
2017/0165372 N-OPTIONALLY SUBSTITUTED ARYL-2-OLIGOMER-3-ALKOXYPROPIONAMIDES
The invention relates to (among other things) N-optionally substituted aryl-2-oligomer-3-alkoxypropionamides and compositions comprising the same. A compound...
2017/0165371 NOVEL SYNTHESIS OF POTENTIAL ESTER PRODRUGS
Esters prodrugs that cross the blood brain barrier can be ideal drugs for treatment of diseases of the central nervous system because the cerebral spinal fluid...
2017/0165370 ANTIBODY-SN-38 IMMUNOCONJUGATES WITH A CL2A LINKER
The present invention concerns improved methods and compositions for preparing SN-38 conjugates of proteins or peptides, preferably immunoconjugates of...
2017/0165369 METHOD OF TREATING CANCER
The invention provides a method for treating cancer using a coadministration strategy that combines local codelivery of a therapeutic agent and an...
2017/0165368 METHOD FOR TREATING RETINAL CONDITIONS USING AN INTRAOCULAR TAMPONADE
Composition comprising at least one fatty acid glycerol ester for use during or after a vitrectomy procedure, said composition being bioresorbable, being...
2017/0165367 COMPOSITIONS COMPRISING SALBUTAMOL SULPHATE
A pharmaceutical composition is described that is suitable for delivery from a pressurised container. The composition is free of polar excipients and...
2017/0165366 Anti-TIGIT Antigen-Binding Proteins and Methods of Use Thereof
Provided herein are antigen-binding proteins (ABPs) that selectively bind to TIGIT and its isoforms and homologs, and compositions comprising the ABPs. Also...
2017/0165365 HUMANIZED PAN-HER ANTIBODY COMPOSITIONS
The invention relates to humanized recombinant antibodies targeting the EGFR family receptors EGFR, HER2 and HER3, compositions comprising at least one...
2017/0165364 THERAPEUTIC AGENT FOR SOLID CANCER
Disclosed is a novel means effective for treatment, metastasis-inhibition, and recurrence-inhibition of human solid cancer. A therapeutic agent for solid...
2017/0165363 CANCER CELL MIGRATION INHIBITORS AND THEIR USE IN THERAPEUTIC TREATMENTS
Described are methods of treating or preventing cancer in patients by administering Interleukin 6 (IL-6) inhibitor and Interleukin 8 (IL-8) inhibitor, in a...
2017/0165361 TREATMENT OF LYSOSOMAL DISORDERS (ANTI-TNF THERAPY)
The invention relates to methods for treating a Lysosomal storage disease (LSD) in a patient. Kits for use in such methods are also provided.
2017/0165360 Methods of Treating Autoimmune Diseases
Novel methods for treating patients with autoimmune diseases are disclosed. The methods of the invention include first depleting circulating lymphocytes in the...
2017/0165359 IMMUNOSTIMULATORY COMBINATIONS OF TLR LIGANDS AND METHODS OF USE
The present invention provides immunostimulatory combinations of TLR ligands and therapeutic and/or prophylactic methods that include administering an...
2017/0165358 METHODS FOR ENHANCING THE IMMUNOSTIMULATION POTENCY OF ALUMINUM SALT-ABSORBED VACCINES
Provided herein are (1) a method of mixing an aluminum salt-adsorbed immunogen with a monophosphoryl lipid A (MPLA)-containing liposome (L(MPLA)), and (2) the...
2017/0165357 Immunotherapy Composition and Use Thereof
The present invention relates to the field of preventing or reducing incidence or severity of an allergic immune response, and compositions for preventing or...
2017/0165355 HUMAN IMMUNODEFICIENCY VIRUS ANTIGENS, VECTORS, COMPOSITIONS, AND METHODS OF USE THEREOF
Synthetic HIV envelope proteins, vectors and compositions thereof, and methods for inducing protective immunity against human immunodeficiency virus (HIV)...
2017/0165354 THERMOSTABLE FREEZE DRIED ROTAVIRUS VACCINE FORMULATION AND PROCESS TO PREPARE THEREOF
The present invention relates to a thermostable freeze dried rotavirus vaccine formulation and the process of preparing the same. More specifically the present...
2017/0165353 Novel Vaccines Against Multiple Subtypes Of Influenza Virus
An aspect of the present invention is directed towards DNA plasmid vaccines capable of generating in a mammal an immune response against a plurality of...
2017/0165352 Influenza Virus Hemagglutinin Protein as a Vaccine Antigen
The invention relates to an influenza viruses hemagglutinin protein as a vaccine antigen against influenza viruses, in particular to a protein being a fragment...
2017/0165350 Filovirus Consensus Antigens, Nucleic Acid Constructs And Vaccines Made Therefrom, And Methods Of Using Same
Nucleic acid molecules and compositions comprising one or more nucleic acid sequences that encode a consensus filovirus immunogen including a consensus...
2017/0165349 RECOMBINANT SUBUNIT WEST NILE VIRUS VACCINE FOR PROTECTION OF HUMAN SUBJECTS
A West Nile virus vaccine for human use is described that preferably contains a recombinantly produced form of truncated West Nile virus envelope glycoprotein...
2017/0165348 VECTOR PRODUCTION
An enveloped viral particle producer or packaging cell, wherein the cell is genetically engineered to decrease expression of MHC-I on the surface of the cell.
2017/0165347 HELICOBACTER THERAPEUTIC
The present invention relates to method of treating and/or preventing inflammation in a subject caused by bacteria that express HtrA. The present invention...
2017/0165346 COMBINATION NEISSERIAL COMPOSITIONS
Compositions comprising a first biological molecule from a Neisseria bacterium and a second biological molecule from a Neisseria bacterium. The term...
2017/0165345 NANOPARTICLES FOR IMMUNE STIMULATION
The invention relates, in part, to nanoparticles, methods for preparing nanoparticles and methods of administering nanoparticles for immune stimulation. An...
2017/0165344 SEROLOGIC CORRELATES OF PROTECTION AGAINST BACILLUS ANTHRACIS INFECTION
Regions of Bacillus anthracis protective antigen are provided representing epitopes recognized by antibodies in subjects that have acquired immunity to...
2017/0165343 VACCINE FOR MYCOPLASMA INFECTION
Disclosed is a vaccine which has a high therapeutic effect on mycoplasma infection and is highly safe. For the purpose of developing effective therapeutic...
2017/0165342 AIPA, OMPA, AND ASP14 IN VACCINE COMPOSITIONS AND DIAGNOSTIC TARGETS FOR ANAPLASMA PHAGOCYTOPHILUM INFECTION
Anaplasma phagocytophilum surface protein AipA and/or fragments thereof which comprise an invasin domain are used in compositions suitable to elicit an immune...
2017/0165341 REPLICATION DEFECTIVE ADENOVIRUS VECTOR IN VACCINATION
Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in...
2017/0165340 NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST CLL AND OTHER CANCERS
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2017/0165338 NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST VARIOUS CANCERS
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2017/0165337 NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST CLL AND OTHER CANCERS
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2017/0165336 METHODS AND COMPOSITIONS FOR TRANSGENE EXPRESSION IN A HERPESVIRUS VECTOR SYSTEM
Compositions are provided comprising a replication-competent herpesvirus vector system and/or a herpesvirus vector particle comprising a heterologous...
2017/0165335 NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST PANCREATIC CANCER AND OTHER CANCERS
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2017/0165334 Methods to Treat Diseases with Protein, Peptide, Antigen Modification and Hemopurification
The current invention discloses methods to modify protein and peptide and antigen to treat disease such as pathogen infection, autoimmune diseases and cancer....
2017/0165333 COMPOSITIONS AND METHODS FOR INDUCING IMMUNE TOLERANCE
The present invention provides liposomal compositions for inducing immune tolerance. The compounds typically comprise a liposome displaying a specific antigen...
2017/0165332 GENE EDITED ANTIGEN PRESENTING CELLS
Disclosed are cells, compositions of matter, and protocols, useful for stimulation of antigen-specific immunity or tolerogenesis by gene editing of immune...
2017/0165331 Botulinum Toxin and the Treatment of Primary Disorders of Mood and Affect
The invention provides methods for treating primary disorders of mood and affect, including depressive disorders, anxiety and sleep disorders and CNS disorders...
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