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Patent # Description
2017/0198281 SEMI-SYNTHETIC NURSE SHARK VNAR LIBRARIES FOR MAKING AND USING SELECTIVE BINDING COMPOUNDS
The present invention relates to VNAR single chain antibodies and more particularly, to semi-synthetic VNAR libraries derived from nurse shark which may be...
2017/0198280 METHODS FOR ISOLATING MICROVESICLES AND EXTRACTING NUCLEIC ACIDS FROM BIOLOGICAL SAMPLES
The invention provides novel methods and kits for isolating nucleic acids from biological samples, including cell-free DNA and/or cell-free DNA and nucleic...
2017/0198279 METHOD FOR ISOLATING RNA WITH HIGH YIELD
A phenol-free method for isolating a nucleic acid from a sample is provided, said method comprising the following steps: a) preparing a precipitation mixture...
2017/0198278 NUCLEIC ACID PREPARATION COMPOSITIONS AND METHODS
Provided herein are methods and compositions to extract and enrich by, physical separation or amplification, relatively short nucleic acids from a nucleic acid...
2017/0198277 Compositions and Methods for Improving Homogeneity of DNA Generated Using a CRISPR/Cas9 Cleavage System
The invention relates to the unexpected discovery of a system and methods for precise homology directed repair after CRISPR/Cas9 cleavage. The invention...
2017/0198276 PERFORMANCE ENHANCING GENETIC VARIANTS OF E. COLI
The invention provides mutant Escherichia coli cells that contain one or more mutations in one or more of the rpoB, hns/tdk, cor A, ygaZ, iap, metL, ygeW, and...
2017/0198275 3D-PRINTED MINIATURE BIOLOGICAL CONSTRUCTS
A method of creating a miniature multicellular biological construct and a method for studying cellular environments using the miniature multicellular...
2017/0198274 Human Coagulation Factor VII Polypeptides
The present invention relates to novel human coagulation Factor VIIa variants having coagulant activity as well as polynucleotide constructs encoding such...
2017/0198273 TAU PROTEASE COMPOSITIONS AND METHODS OF USE
Disclosed are mammalian tau proteases, as well as proteolytically-active fragments, variants, and mutants thereof. Also disclosed are polynucleotides and...
2017/0198272 PROLINE-SPECIFIC ENDOPROTEASE AND USE THEREOF
The present invention relates to a polypeptide having proline-specific endoprotease activity, wherein the polypeptide has less than 70% residual activity when...
2017/0198271 NOVEL BETA-GALACTOSIDASE
The present invention relates to a novel beta-galactosidase, and more particularly to a novel beta-galactosidase derived from Bacillus circulans, a gene...
2017/0198270 SYSTEMS AND METHODS FOR PRODUCTION AND USE OF FUNGAL GLYCOSYL HYDROLASES
Compositions comprising glycosyl hydrolase enzymes are provided, as are methods for their use to depolymerize hemicellulose, cellulose, lignin and pectin in...
2017/0198269 ENGINEERING AND OPTIMIZATION OF IMPROVED SYSTEMS, METHODS AND ENZYME COMPOSITIONS FOR SEQUENCE MANIPULATION
The invention provides for engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target...
2017/0198268 Compositions and Methods for Site-Directed DNA Nicking and Cleaving
Aspects of the disclosure relate to compositions and methods for site-directed DNA nicking and/or cleaving, and use thereof in, for example, polynucleotide...
2017/0198267 NUCLEIC ACID MODIFYING ENZYMES
This invention provides for an improved generation of novel nucleic acid modifying enzymes. The improvement is the fusion of a sequence-non-specific...
2017/0198266 CONSTRUCTS AND METHODS FOR PLANT TRANSFORMATION
Compositions and transformation methods to increase the frequency of plants in a population of transformed plants which have a single copy of the target...
2017/0198265 ADENO-ASSOCIATED VIRUS VECTOR VARIANTS FOR HIGH EFFICIENCY GENOME EDITING AND METHODS THEREOF
Adeno-associated virus (AAV) Clade F vectors or AAV vector variants (relative to AAV9) for precise editing of the genome of a cell and methods and kits thereof...
2017/0198264 Recombinant Influenza Viruses for Vaccines and Gene Therapy
The invention provides compositions and methods useful to prepare segmented, negative strand RNA viruses, e.g., orthomyxoviruses such as influenza A viruses,...
2017/0198263 Recombinant AAV Vectors Expressing Osteoprotective genes, including HAS2 and Lubricin, useful in the Treatment...
The present disclosure relates to recombinant viral vectors, to pharmaceutical compositions comprising such recombinant vectors, and to methods for prevention...
2017/0198262 CULTURE MEDIUM AND CULTURING METHOD FOR ANCHORAGE-DEPENDENT CELLS, CELL COMPOSITION INCLUDING STEM CELLS AND/OR...
As a technique capable of culturing anchorage-dependent cells without using an anchorage, provided is a medium for anchorage-dependent cells, which comprises...
2017/0198261 SINGLE CELL-DERIVED ORGANOIDS
The present invention relates to organoids derived from a single cell, such as a prostate cancer cell, and methods and compositions relating to the production...
2017/0198260 METHOD FOR PRODUCING MESOTHELIAL CELLS AND A CELL SHEET FOR PREVENTING ADHESION
An object of the present invention is to provide a method for differentiating mesodermal cells into mesothelium cells. The present invention provides a method...
2017/0198259 METHOD AND ASSEMBLY FOR EXTRACTION OF REGENERATIVE CELLULAR COMPONENTS FROM ADIPOSE TISSUE
The present invention concerns a novel method and assembly for extraction of regenerative cellular components from an adipose tissue, the method comprising the...
2017/0198257 Generation Of A Mesenchymal Stromal Cell Bank From The Pooled Mononuclear Cells Of Multiple Bone Marrow Donors
The present invention pertains to an improved mesenchymal stromal cell (MSC) preparation and a method for producing the same. The invention provides a new...
2017/0198256 ENCAPSULATION AND CARDIAC DIFFERENTIATION OF hiPSCs IN 3D PEG-FIBRINOGEN HYDROGELS
The present invention relates to the production of cell cultures and tissues from undifferentiated pluripotent stem cells using three-dimensional biomimetic...
2017/0198255 INDUCED PLURIPOTENT CELL-DERIVED OLIGODENDROCYTE PROGENITOR CELLS FOR THE TREATMENT OF MYELIN DISORDERS
The present invention relates to preparations of induced pluripotent cell-derived oligodendrocyte progenitor cells, and methods of making, isolating, and using...
2017/0198254 SPECIFIC MEDIUM FOR LONG-TERM MAINTENANCE AND PROLIFERATION SUBCULTURE OF HUMAN HEPATOCYTES AND CULTURE METHOD
A specific culture medium and culture method are for long-term maintenance, proliferation and passaging of human hepatocytes. The culture medium contains a...
2017/0198253 METHODS AND COMPOSITIONS FOR KILLING SENESCENT CELLS AND FOR TREATING SENESCENCE-ASSOCIATED DISEASES AND DISORDERS
Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic...
2017/0198252 DEVICE AND METHODS FOR PRINTING BIOLOGICAL TISSUES AND ORGANS
The invention relates to medicine and biology, particularly to the means for artificial manufacturing of biological tissues and organs, and can be used in...
2017/0198251 Media for Cell Culture
The present disclosure relates, in general, to a media, e.g., a serum replacement, media supplement, complete media or cryopreservation media, comprising a...
2017/0198250 Compositions and Methods for Extending Storage Time of Competent Cells at -20.degree.C
Compositions and methods are provided for storing prokaryotic cells including competent prokaryotic cells at -20.degree. C. in a buffer so that the cells are...
2017/0198249 LIQUID FEEDING DEVICE AND CELL CULTURE DEVICE
There is the problem that a liquid culture medium fed by a pump has a high frequency of contact with a gas during movement in a tube, and the pH value of the...
2017/0198248 CELL SEPARATION FILTER AND CELL CULTURE VESSEL
A cell separation filter has a plate-shaped base portion, one or more porous areas, provided on the base portion, in which holes are formed in order to...
2017/0198247 FLUID LINE ARRANGEMENT COMPRISING A PLURALITY OF FLUID LINE ELEMENTS, VALVE LINE ARRANGEMENT COMPRISING A FLUID...
A fluid line element for building a fluid line section comprising a plurality of identical fluid line elements, wherein the fluid line element comprises: an...
2017/0198246 MULTIPURPOSE BIOREACTOR
A multiuse bioreactor that is a single-use bioreactor, a development bioreactor, a commercial manufacturing bioreactor, a batch, a fed-batch, a perfusion and...
2017/0198245 METHOD FOR MANUFACTURING MICRO-HEMISPHERE ARRAY PLATE, MICROFLUIDIC DEVICE COMPRISING MICRO-HEMISPHERE ARRAY...
The present invention relates to a method for manufacturing a micro-hemisphere array plate, a microfluidic device comprising the micro-hemisphere array plate,...
2017/0198244 PHOTOBIOREACTOR WITH MATS MADE FROM LIGHT-DECOUPLING OPTICAL FIBRES AND ELECTRICALLY CONDUCTIVE FIBRES...
A photobioreactor is described for cultivating phototrophic organisms and in particular a mat, as can be used in one such photobioreactor. The mat has a...
2017/0198243 LIQUID CLEANING AGENT CONTAINING LIQUID AND SOLID ENZYME FORMULATIONS
Liquid cleaning agents and methods for cleaning are provided herein. In one embodiment, the liquid cleaning agent includes at least one liquid enzyme...
2017/0198242 CLEARCOAT CONTAINING THERMOLYSIN-LIKE PROTEASE FOR EASY-CLEANING OF INSECT BODY STAINS
Provided are processes for facilitating the removal of a biological stain is provided wherein a substrate or coating including a protease is capable of...
2017/0198241 Improved Detergent Composition
The invention relates to a colour stable liquid or gel detergent composition comprising an aminocarboxylate builder, a dye and a polyalkyleneimine.
2017/0198240 POLYMERS FOR INDUSTRIAL LAUNDRY DETERGENTS
The invention discloses detergent compositions containing acrylic acid polymers, including methacrylic acid/ethyl acrylate polymers. In certain embodiments...
2017/0198239 COMPOSITION AND PROCESS OF MAKING AN AMINO SILICONE BASED DELAYED ANTIFOAM FOR USE IN LAUNDRY DETERGENT
A delayed antifoam composition used in laundry detergent comprising an amino silicone antifoam fluid that selectively use alkyl groups selectively being R and...
2017/0198238 FABRIC-SOFTENING COMPOSITION COMPRISING AN HEUR THICKENER
The present invention relates to a fabric-softening composition, comprising a cationic fabric softening agent and a thickening polyurethane resulting from the...
2017/0198237 LAUNDRY DETERGENT COMPOSITIONS COMPRISING RENEWABLE COMPONENTS
The present disclosure relates to detergent compositions that comprise renewable components and exhibit good performance, as compared to both traditional...
2017/0198236 Refrigerating-Machine Oil Composition and Working Fluid Composition Including Same for Refrigerating Machine
The present invention provides a refrigerating-machine oil composition which comprises the following ester additive (a) and the following ester base oil (b),...
2017/0198235 GASOLINE ENGINE LUBRICANT OIL COMPOSITION AND MANUFACTURING METHOD THEREFOR
Provided is a lubricating oil composition capable of revealing fuel consumption reducing properties due to a friction reducing effect within a short period of...
2017/0198234 LUBRICATING OIL COMPOSITION
A lubricating oil composition containing a lubricating base oil and on the basis of the total mass of the composition, (A) a boron-containing ashless...
2017/0198233 LUBRICATING COMPOSITION CONTAINING AN OXYALKYLATED HYDROCARBYL PHENOL
The invention provides lubricating composition comprising: an oil of lubricating viscosity, and an oxyalkylated hydrocarbyl phenol, wherein the oxyalkylated...
2017/0198232 LUBRICATION OIL ADDITIVE AND METHOD FOR MANUFACTURING SAME, AND LUBRICATION OIL COMPOSITION USING SAME
Through a lubricating oil additive including an amide compound represented by the following general formula (1) and a lubricating oil composition using the...
2017/0198231 METHOD AND COMPOSITION FOR CONTEMPORANEOUSLY DIMERIZING AND HYDRATING A FEED HAVING BUTENE TO PRODUCE A...
Methods for producing alcohols and oligomers contemporaneously from a hydrocarbon feed containing mixed butenes using an acid based catalyst are provided....
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