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Patent # Description
2017/0198078 FUNCTIONALIZED BLOCK COMPOSITE AND CRYSTALLINE BLOCK COMPOSITE COMPOSITIONS
The invention provides functionalized block composites and crystalline block composites. In particular, the invention provides a functionalized olefin-based...
2017/0198077 CONTACT LENS AND PROCESS FOR PRODUCING SAME
A contact lens is provided as hydrate of a copolymer of at least three components including (I) both terminal-polymerizable silicone oligomer exhibiting...
2017/0198076 CURABLE COMPOSITION AND POLYMER
An object of the invention is to provide a curable composition having a HALS skeleton and capable of producing polymers having excellent weather resistance and...
2017/0198075 Methods For Making Fluorided Chromium (VI) Catalysts, And Polymerization Processes Using the Same
Methods for preparing a fluorided chromium catalyst can include a step of calcining a supported chromium catalyst at a peak calcining temperature to produce a...
2017/0198074 TRANSITION METAL COMPOUND, CATALYST COMPOSITION COMPRISING THE SAME, AND METHOD OF PREPARING POLYOLEFIN
The present invention relates to a novel transition metal compound, a catalyst composition comprising the transition metal compound, and a method of preparing...
2017/0198073 METHOD FOR PRODUCING DIMETHYL POLYVINYLPHOSPHONATE AND POLYVINYLPHOSPHONIC ACID
A method for producing poly(dimethyl vinylphosphonate) from a monomer component mainly containing dimethyl vinylphosphonate by anionic polymerization in the...
2017/0198072 PROCATALYST FOR POLYMERIZATION OF OLEFINS
The present invention relates to a procatalyst comprising the compound represented by Formula (A), preferably the Fischer projection of formula (A) as an...
2017/0198071 PROCATALYST FOR POLYMERIZATION OF OLEFINS
The present invention relates to a procatalyst comprising the compound represented by formula A as an internal electron donor, wherein: R.sup.81, R.sup.82,...
2017/0198070 AQUEOUS POLYMERIZATION OF FLUORINATED MONOMER USING POLYMERIZATION AGENT COMPRISING FLUOROPOLYETHER ACID OR...
A process comprising polymerizing at least one fluorinated monomer in an aqueous medium containing initiator and polymerization agent to form an aqueous...
2017/0198069 POLYETHYLENE COMPOSITION FOR INJECTION MOULDING
Polyethylene composition for injection molding with a beneficial balance of environmental stress cracking resistance and impact resistance in combination with...
2017/0198068 DISPERSION STABILIZER FOR SUSPENSION POLYMERIZATION, PRODUCTION METHOD FOR VINYL-BASED POLYMER, AND VINYL...
Provided is a dispersion stabilizer which exhibits an excellent polymerization stability when used in suspension polymerization for a vinyl chloride-based...
2017/0198067 PREPARATION OF CHLORINATED POLYVINYL CHLORIDE
The present disclosure relates to a process for the preparation of CPVC which includes reacting PVC with chlorine at a pre-determined temperature in the...
2017/0198066 PACKAGE FOR PELLETS OF SAPONIFIED ETHYLENE-VINYL ESTER-BASED COPOLYMER OR RESIN COMPOSITION THEREOF
The purpose of the invention is to provide: a package for EVOH resin pellets which is capable of providing the EVOH resin pellets almost free from powder even...
2017/0198065 PROCESS FOR THE ISOLATION OF SULFONYL FLUORIDE POLYMERS AND POLYMERS OBTAINED THEREFROM
The invention relates to a process for the isolation of (per)fluorinated polymers containing sulfonyl fluoride functional groups from a polymerization latex....
2017/0198064 METHOD FOR PRODUCING CLEAN THERMOPLASTIC PARTICLES
A process for increasing purity of a low density polyethylene (LDPE) composition, comprising the steps of: a) providing a melted composition comprising LDPE...
2017/0198063 ACTIVE ENERGY RAY-CURABLE COMPOSITION AND ANTISTATIC FILM
Provided are an active energy ray-curable composition that has good antistatic properties, scratch resistance, and transparency after curing, and an antistatic...
2017/0198062 MULTI-SPECIFIC ANTIBODY CONSTRUCTS
The present disclosure relates to a multi-specific antibody molecule comprising or consisting of: a) a polypeptide chain of formula (I): ...
2017/0198061 INFLUENZA VACCINES AND METHODS OF USE THEREOF
The disclosure relates to anti-idiotypic antibodies and related influenza virus vaccines.
2017/0198060 FUNGAL-SPECIFIC METALLOPROTEASES AND USES THEREOF
The present invention relates to methods of reducing, delaying, preventing and/or inhibiting the progression of a Cryptococcus infection into the central...
2017/0198059 CRYSTALLINE ANTIBODY FORMULATIONS
Described herein are anti-PCSK9 antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals.
2017/0198058 CRYSTALLINE ANTIBODY FORMULATIONS
Described herein are anti-PCSK9 antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals.
2017/0198057 MITIGATION OF LUNG INJURY
Inhibition of human epidermal growth factor receptor 2, human epidermal growth factor receptor 3, or of the heterodimerization of these proteins has presently...
2017/0198056 Anti-MUC1 Antibody or Antigen-Binding Fragment Thereof and Uses Thereof
The present invention provides: an antibody exhibiting specificity for MUC1, the antibody having a glycan structure expressed at high levels in cancer cells; a...
2017/0198055 A DIAGNOSTIC AND THERAPEUTIC TOOL FOR CANCER
Disclosed is a method for determining the likelihood of the presence or progression of a hepatocellular carcinoma in a subject, comprising determining the...
2017/0198054 METHODS FOR TREATING CANCER WITH ANTI BIP OR ANTI MICA ANTIBODIES
The present invention provides method of compositions for treating cancer by inhibiting MIC shedding.
2017/0198053 USE OF SEMAPHORIN-4D BINDING MOLECULES FOR TREATING NEURODEGENERATIVE DISORDERS
Provided herein are methods for alleviating symptoms in a subject having a neurodegenerative disorder, comprising administering to the subject an effective...
2017/0198052 TETRAVALENT ANTI-PSGL-1 ANTIBODIES AND USES THEREOF
Provided herein are tetravalent antibodies that specifically bind to human PSGL-1. Unlike bivalent antibodies, these tetravalent antibodies contain a dimer of...
2017/0198051 MULTIVALENT AND MULTISPECIFIC OX40-BINDING FUSION PROTEINS
This invention relates generally to molecules that specifically engage OX40, a member of the TNF receptor superfamily (TNFRSF). More specifically this...
2017/0198050 MULTIVALENT AND MULTISPECIFIC 41BB-BINDING FUSION PROTEINS
This invention relates generally to molecules that specifically engage 41BB, a member of the TNF receptor superfamily (TNFRSF). More specifically, this...
2017/0198049 METHODS FOR REDUCING EXACERBATION RATES OF ASTHMA USING BENRALIZUMAB
Provided herein is are methods of reducing exacerbations of asthma in an asthma patient, comprising administering to the patient an effective amount of the...
2017/0198048 NOVEL AGENTS AND USES THEREOF
The present invention provides agents comprising or consisting of a binding moiety with specificity for interleukin-1 receptor accessory protein (IL1RAP) for...
2017/0198047 PSGL-1 MODULATORS AND USES THEREOF
The present invention relates to the seminal discovery that P-selectin glycoprotein ligand-1 (PSGL-1) modulates the immune system and immune responses....
2017/0198046 COMPOSITIONS CAPABLE OF SPECIFICALLY BINDING PARTICULAR HUMAN ANTIGEN PRESENTING MOLECULE/ ANTIGEN COMPLEXES...
A composition-of-matter comprising an antibody or antibody fragment including an antigen-binding region capable of specifically binding an antigen-presenting...
2017/0198045 Tri-Specific Binding Molecules and Methods of Use Thereof
The present invention relates to Tri-Specific Binding Molecules, which are multichain polypeptide molecules that possess three Binding Domains and are thus...
2017/0198044 COMPOSITIONS AND METHODS FOR SAFE AND EFFECTIVE IMMUNOTHERAPY
This invention relates to methods and compositions that are useful for the treatment of various diseases, including inflammatory diseases. The invention...
2017/0198043 BISPECIFIC ANTIGEN BINDING MOLECULES
The present invention generally relates to novel bispecific antigen binding molecules. In addition, the present invention relates to polynucleotides encoding...
2017/0198042 ANTI-TIGIT ANTIBODIES
The present invention relates to anti-TIGIT antibodies, as well as use of these antibodies in the treatment of diseases such as cancer and infectious disease.
2017/0198041 ANTIBODY MOLECULES TO TIM-3 AND USES THEREOF
Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune,...
2017/0198040 ANTIBODIES TARGETING CD32b AND METHODS OF USE THEREOF
The present invention relates to isolated antibodies and antigen-binding fragments thereof which selectively bind human CD32b. Also provided herein are...
2017/0198039 METHODS FOR TREATING CANCER
The present invention provides methods of treating cancer, particularly cancers that had developed resistance to PD-1 and PDL-1 blockade. Also included are...
2017/0198038 MULTISPECIFIC NKp46 BINDING PROTEINS
Multispecific proteins that bind and specifically redirect NK cells to lyse a target cell of interest are provided without non-specific activation of NK cells...
2017/0198037 Covalently Bonded Diabodies Having Immunoreactivity with PD-1 and LAG-3, and Methods of Use Thereof
The present invention is directed to bi-specific diabodies that comprise two or more polypeptide chains and which possess at least one Epitope-Binding Site...
2017/0198036 ANTAGONISTS OF IL-6 TO PREVENT OR TREAT CACHEXIA, WEAKNESS, FATIGUE, AND/OR FEVER
The present invention is directed to therapeutic methods using antibodies and fragments thereof having binding specificity for IL-6 to prevent or treat...
2017/0198035 Anti-IL-17A antibodies and their use in treating autoimmune and inflammatory disorders
The present disclosure relates to antibodies and proteins comprising an antigen-binding portion thereof that specifically bind to the pro-inflammatory cytokine...
2017/0198034 METHODS TO CONTROL PROTEIN HETEROGENEITY
The instant invention relates to the field of protein production and in particular to controlled protein heterogeneity compositions and processes for...
2017/0198033 SULFONATED SCLEROSTIN, ANTIBODIES, EPITOPES AND METHODS FOR IDENTIFICATION AND USE THEREFOR
Provided are antibodies that bind to: a sulfonated epitope of the protein Sclerostin, to Sclerostin portions comprising a sulfonated amino acid and to...
2017/0198032 ANTI-PRO/LATENT MYOSTATIN ANTIBODIES AND METHODS OF USE THEREOF
The present invention relates to antibodies that specifically bind pro-myostatin and/or latent myostatin, and methods and uses thereof.
2017/0198031 NOTCH BINDING AGENTS AND ANTAGONISTS AND METHODS OF USE THEREOF
The present invention relates to Notch-binding agents and Notch antagonists and methods of using the agents and/or antagonists for treating diseases such as...
2017/0198030 METHODS OF TREATING ALZHEIMER'S DISEASE
Methods of treating Alzheimer's Disease (AD) in patients suffering from mild to moderate AD, including ApoE4 positive patients and patients suffering from mild...
2017/0198029 SINGLE CHAIN ANTIGEN RECOGNIZING CONSTRUCTS (SCARCS) STABILIZED BY THE INTRODUCTION OF NOVEL DISULFIDE BONDS
The present invention relates to a single chain antigen recognizing construct (scARC), which is composed of stabilized variable domains by the introduction of...
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