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Patent # Description
2017/0232010 DRUG WITH ACTIVITY AGAINST THE HERPES VIRUS FAMILY
The invention relates to medicine, and specifically to synthetic biologically active derivatives of carbopentoxysulfanilic acid. The novel substance comprises...
2017/0232009 Methods of Using Qiapine
Methods of treating renal failure are described in particular, methods of treating renal failure by administration of pharmaceutical composition including a...
2017/0232008 MULTI-INGREDIENT PHARMACEUTICAL COMPOSITION FOR USE IN CANCER THERAPY
A pharmaceutical composition or kit of parts comprising at least three ingredients from a HMG-CoA reductase inhibitor, a leukotriene antagonist, a proton pump...
2017/0232007 METHODS AND COMPOSITIONS FOR TREATING ALCOHOL USE DISORDERS
Disclosed are methods and compositions for treating alcohol dependence by administration to a patient of an inhibitor of 11.beta.-hydroxysteroid dehydrogenases...
2017/0232006 NEUROACTIVE 19-ALKOXY-17-SUBSTITUTED STEROIDS, PRODRUGS THEREOF, AND METHODS OF TREATMENT USING SAME
The present disclosure is generally directed to neuroactive 19-alkoxy-17-substituted steroids as referenced herein, and pharmaceutically acceptable salts...
2017/0232005 System and Method for Diagnosis and Treatment
This invention relates the use of cortisol blockers (glucocorticoid receptor [GR] antagonists) for the treating or preventing treatment resistant prostate...
2017/0232004 METHODS FOR TREATING FUNGAL INFECTIONS
Disclosed herein are methods of treating fungal infections in a patient, comprising identifying a patient in need of treatment and administering a ...
2017/0232003 COMPOSITIONS AND METHODS FOR MAINTAINING COGNITIVE FUNCTION
Provided are methods for reducing the progression of cognitive decline in a post-menopausal woman using a continuous regimen of estrogen in combination with...
2017/0232002 COMMERCIAL SCALE PRODUCTION METHODS FOR TRANSDERMAL HORMONE FORMULATIONS
Methods for commercial production of transdermal formulations comprising a hormone compound are provided. In particular, methods for commercial scale...
2017/0232001 METHOD AND COMPOSITION FOR TREATING MIGRAINES
A method for treating migraines is disclosed. The method utilizes a rapid drug delivery system which prevents deactivation or degradation of the active agent,...
2017/0232000 METHODS OF TREATMENT USING SELECTIVE BCL-2 INHIBITORS
This invention pertains to methods of treating systemic lupus erythematosus and Sjogren's Syndrome with compounds that selectively inhibit the activity of...
2017/0231999 IDO INHIBITORS
There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said...
2017/0231998 Pyrazolopyridine Derivatives, Preparation Process Therefor And Therapeutic Use Thereof
The invention relates to FGF-inhibiting pyrazolopyrimidine derivatives of general formula (I) to a process for preparing them and to the therapeutic use...
2017/0231997 Tablet Formulation Of 2-Fluoro-N-Methyl-4-[ 7- ( Quinolin-6-Ylmethyl) Imidazo [1,2-B] [1,2,4] Triazin-2-YL]...
The present invention is related to tablets comprising of 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-- 2-yl]benzamide, processes...
2017/0231996 STABLE EDIBLE SUPERSATURATED CAFFEINE SOLUTIUONS AND METHODS OF MAKING THE SAME
The present disclosure is generally directed to energy drinks, specifically, the present disclosure is directed to energy drinks having supersaturated caffeine...
2017/0231995 BTK Inhibitors to Treat Solid Tumors Through Modulation of the Tumor Microenvironment
In certain embodiments, the invention includes therapeutic methods of using a BTK inhibitor to treat solid tumor cancers by modulation of the tumor...
2017/0231994 ORGANIC COMPOUNDS
Provided are PDE1 inhibitors of Formula I, processes for their production, their use as pharmaceuticals, and pharmaceutical compositions comprising them.
2017/0231993 Solid Pharmaceutical Compositions Containing An Integrase Inhibitor
Compressed tablets for oral administration containing raltegravir in the form of a pharmaceutically acceptable salt are described. The tablets comprise: (A)...
2017/0231992 COMPOUNDS FOR USE IN TREATING ACUTE CORONARY SYNDROME AND RELATED CONDITIONS
Provided herein are compounds and pharmaceutically acceptable salts thereof that are useful therapeutics for acute coronary syndrome and related disorders.
2017/0231991 Use Of Modulators Of CCR5 In The Treatment Of Cancer And Cancer Metastasis
This disclosure is directed, in part, to a method of determining whether a subject having cancer is at risk for developing metastasis of the cancer. In one...
2017/0231990 PHENYLOXADIAZOLE DERIVATIVES AS PGDS INHIBITORS
This invention is directed to a compound of formula (I): ##STR00001## wherein R1, R2 and R3 are as defined herein, a pharmaceutical composition comprising the...
2017/0231989 MULTI-LAYERED TABLET CONTAINING DRUG UNSTABLE TO LIGHT
An oral disintegrating tablet which contains rosuvastatin or a salt thereof and is stable to light is provided. An oral disintegrating tablet stable to light,...
2017/0231988 Pharmaceutical Composition of Rosuvastatin Calcium
The invention relates to pharmaceutical compositions containing rosuvastatin calcium of formula (I) and processes for their manufacture. ##STR00001##
2017/0231987 LEVOSIMENDAN FOR USE IN THE TREATMENT OF MOTOR NEURON DISEASES (E.G. ALS)
The present invention relates to a method of treating motor neuron diseases such as amyotrophic lateral sclerosis (ALS) using levosimendan or its active...
2017/0231986 Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a BCL-2 Inhibitor
Therapeutic combinations of a phosphoinositide 3-kinase (PI3K) inhibitor, including PI3K inhibitors selective for the .gamma.- and .delta.-isoforms and...
2017/0231984 COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES
The invention relates to certain compounds or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as ...
2017/0231983 Piperazine-Substituted Benzothiophenes For Treatment of Mental Disorders
The present invention provides a heterocyclic compound represented by the general formula (1): The compound of the present invention has a wide treatment...
2017/0231982 METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF CARDIAC HYPERTROPHY
Methods are provided of treating cardiac hypertrophy in a mammalian subject comprising administering to the subject an anti-hypertrophic effective amount of an...
2017/0231981 COMPOSITIONS OF MULTIPLE ARIPIPRAZOLE PRODRUGS
Described herein is a composition comprising: (a) a first population of particles of a first aripiprazole prodrug; and (b) a second population of particles of...
2017/0231980 USE OF LEVOCETIRIZINE AND MONTELUKAST IN THE TREATMENT OF VASCULITIS
The embodiments described herein include methods and formulations for treating vasculitis. The methods and formulations include, but are not limited to,...
2017/0231979 Methods and Compositions for Treating Vasomotor Symptoms
The present disclosure is generally directed to compositions and methods for treating or limiting development of vasomotor symptoms in a subject.
2017/0231978 MATRIX FOR SUSTAINED, INVARIANT AND INDEPENDENT RELEASE OF ACTIVE COMPOUNDS
The invention concerns a storage stable pharmaceutical formulation comprising preferably two active compounds in a non-swellable diffusion matrix, whereby the...
2017/0231977 MULTIDIRECTIONAL MUCOSAL DELIVERY DEVICES AND METHODS OF USE
The present invention relates to a pharmaceutical dosage form for transmucosal delivery of an active agent to two or more mucosal surfaces. The dosage form is...
2017/0231976 8'-HYDROXY-DIHYDROERGOTAMINE COMPOUNDS AND COMPOSITIONS
8'-Hydroxy-Dihydroergotamine (8'-OH DHE) medicinal compounds, compositions, and dosage forms containing such compositions are provided. Also provided herein...
2017/0231975 Kinase Inhibitors
The disclosed molecules are inhibitors of Bcr-Abl and Src kinases. The molecules are cytotoxic to Gleevec resistant cells. Inhibitors of Bcr-Abl and Src...
2017/0231974 Combined Use of an Alpha-Adrenergic Receptor Antagonist and an Anti-Muscarinic Agent
The combined use of (R)-5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzene-1-sulf- onamide (tamsulosin), or its pharmaceutically acceptable salt,...
2017/0231973 QUINOLINE CONTAINING COMPOUNDS AND THEIR USE FOR TREATING ENDOPLASMIC RETICULUM STRESS-RELATED DISEASES
Provided herein are quinoline, pharmaceutical compositions thereof, and methods of their use for treating, preventing, or ameliorating one or more symptoms of...
2017/0231972 ANTINEOPLASTIC COMBINATIONS CONTAINING HKI-272 AND VINORELBINE
A combination of HKI-272 compound and a vinorelbine compound in the treatment of a neoplasm is provided. Regimens, kits, and method for treatment of neoplasm,...
2017/0231971 TREATMENT OF OCULAR INFLAMMATORY DISEASES USING LAQUINIMOD
Disclosed is a method for treating an ocular inflammatory disease (OID), e.g., uveitis or conjunctivitis, comprising periodic administration of a ...
2017/0231970 SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE- -3-CARBOXAMIDE
The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline- -3-carboxamide (Compound 1),...
2017/0231969 Pharmaceutical Compositions of Edoxaban
Edoxaban is factor X inhibitor useful for the treatment or the prevention of thrombosis or embolism. A pharmaceutical composition comprising Edoxaban, or a...
2017/0231968 METHOD FOR RELIEF OF AND TREATMENT OF PRURITUS
A method for treating pruritus by topically applying a composition comprising a hedgehog inhibitor compound is provided.
2017/0231967 Bach1 Inhibitors in Combination with Nrf2 Activators and Pharmaceutical Compositions Thereof
The disclosure provides pharmaceutical compositions comprising Bach1 Inhibitors and Nrf2 Activators. The disclosure also provides methods of treating diseases...
2017/0231966 INHIBITION OF IL-2 PRODUCTION
An object is to find a substance which inhibits IL-2 production. IL-2 production can be inhibited by a compound represented by the following formula (I): ...
2017/0231965 PHARMACEUTICAL COMPOSITION FOR MODIFIED RELEASE
A pharmaceutical composition for modified release, comprising (1) (R)-2-(2-aminothiazol-4-yl)-4'-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]a- cetic acid anilide,...
2017/0231964 PHARMACEUTICAL COMPOSITIONS DIRECTLY TARGETING FKBP52 FOR THE TREATMENT OF PROSTATE CANCER AND METHODS OF USING...
Embodiments of the current invention include methods and compositions for regulating the activity of hormone receptors.
2017/0231963 PREPARATION OF AND FORMULATION COMPRISING A MEK INHIBITOR
The present invention relates to processes for preparing 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-car- boxylic acid...
2017/0231962 Compound Combinations for Attenuation of Bacterial Virulence
Methods for modulating quorum sensing in certain Gram-negative bacteria having multiple QS systems including Las, Rhl, and Pqs with associated receptors (LasR,...
2017/0231961 PYRAZOLINE-DERIVED COMPOUND AND ITS USE IN A WEEKLY DOSAGE REGIME AGAINST INFLAMMATION AND PAIN DERIVED FROM...
The present invention refers to the use of the compounds E-6087 in a weekly dosage regime for the treatment of pain and inflammation associated to a...
2017/0231960 METHODS OF TREATING OR PREVENTING MULTIPLE SCLEROSIS
A method of treating or preventing multiple sclerosis includes administering a therapeutically effective amount of a cyclohexane derivative represented by...
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