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Patent # Description
2017/0247725 IN VIVO AND IN VITRO OLEFIN CYCLOPROPANATION CATALYZED BY HEME ENZYMES
The present invention provides methods for catalyzing the conversion of an olefin to any compound containing one or more cyclopropane functional groups using...
2017/0247724 METHODS FOR CONTROL OF FLUX IN METABOLIC PATHWAYS
The invention pertains to a method for preparing cells that can be used as biocatalysts by inducing in them a growth-decoupled state, in which interferase...
2017/0247723 PROCESS TO PRODUCE ORGANIC COMPOUNDS FROM SYNTHESIS GASES
At least one isolated microorganism and a fermentation method to convert hydrogen gas, carbon dioxide gas, and/or carbon monoxide gas to a lower alkyl alcohol...
2017/0247722 PROCESS FOR ENZYMATIC HYDROLYSIS OF LIGNOCELLULOSIC MATERIAL AND FERMENTATION OF SUGARS
The invention relates to a process for the preparation of a sugar and/or fermentation product from lignocellulosic material.
2017/0247721 APPARATUS AND METHOD FOR REDUCTION OF PHENOL IN ENZYMATIC SOLUTIONS AND/OR FEEDSTOCK
Provided are an apparatus and method for reducing the phenol concentration in a commercial enzyme solution and/or feedstock.
2017/0247720 BIOLOGICAL PROCESS FOR PRODUCING MAGNETIC NANOPARTICLES
A process for obtaining gold magnetic nanoparticles or of other metallic elements by fermenting a culture medium in the presence of producer microorganisms...
2017/0247719 COMPOSITIONS AND METHODS TO CONTROL INSECT PESTS
Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as a Coleopteran plant pest or a...
2017/0247718 METHODS AND COMPOSITIONS FOR ROOT KNOT NEMATODE CONTROL
The present invention discloses gene targets, constructs and methods for the genetic control of plant disease caused by nematodes of the genus Meloidogyne...
2017/0247717 METHOD FOR PLANT IMPROVEMENT USING A TRANSGENE CONTAINING THE BETL9 PROMOTER DRIVING EXPRESSION OF THE MRP1 PROTEIN
The invention relates to the field of plant improvement, in particular of the improvement of yield for plants, by using a transgene containing the BETL9...
2017/0247716 MODULATION OF RTL GENE EXPRESSION AND IMPROVING AGRONOMIC TRAITS
Nucleotide sequences encoding RTL polypeptides are provided herein, along with plants and cells having increased levels of RTL gene expression, increased...
2017/0247715 GENETICALLY MODIFIED PLANTS HAVING ALTERED LIGNIN CONTENT
The invention relates to methods for producing a plant with altered lignin content by genetically manipulating expression of a PIRIN gene. The said method...
2017/0247714 Synthesis of Sialic Acid in Plants
A method of synthesizing sialic acid in plants, and plants capable of synthesizing sialic acid is provided. Furthermore, a method of producing sialylated...
2017/0247713 TRICHOME-SPECIFIC TRANSCRIPTION FACTOR MODULATING TERPENE BIOSYNTHESIS
The present invention relates to identification and isolation of zinc finger transcription factor in tomato that specifically expresses in glandular trichomes...
2017/0247712 RECOMBINANT PROMOTER WITH INCREASED FIBER-SPECIFIC EXPRESSION
The present application discloses a recombinant fiber-selective promoter region comprising a DNA molecule comprising a fiber specificity region of a cotton...
2017/0247711 ZEA MAYS REGULATORY ELEMENTS AND USES THEREOF
Provided are constructs and methods for expressing a transgene in plant cells and/or plant tissues using Zea mays chlorophyll a/b binding gene regulatory...
2017/0247710 CRISPR/CAS SYSTEMS FOR C1-FIXING BACTERIA
The invention provides methods of genetically engineering a C1-fixing bacterium using a Clustered Regularly Interspaced Short Palindromic Repeats...
2017/0247709 EUKARYOTIC ORGANISMS AND METHODS FOR INCREASING THE AVAILABILITY OF CYTOSOLIC ACETYL-COA, AND FOR PRODUCING...
Provided herein are non-naturally occurring eukaryotic organisms that can be engineered to produce and increase the availability of cytosolic acetyl-CoA. Also...
2017/0247708 METHODS, SYSTEMS, AND COMPOSITIONS FOR CELL-DERIVED/VESICLE-BASED MICRORNA DELIVERY
Some embodiments comprise methods, systems, and compositions to produce and/or administer modified exosomes or other vesicles containing one or more selected...
2017/0247707 INTERFERING RNA MOLECULES
The present invention is related to a ribonucleic acid comprising a double stranded structure whereby the double-stranded structure comprises a first strand...
2017/0247706 CDC25A INHIBITOR FOR THE TREATMENT OF DRUG RESISTANT CANCER OR FOR THE PREVENTION OF TUMOR RELAPSE
The present invention concerns a CDC25A phosphatase inhibitor for use in the treatment of a drug resistant cancer and/or in prevention of tumor relapse in a...
2017/0247705 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ERYTHROPOIETIC PROTOPORPHYRIA
The present invention relates to methods and pharmaceutical compositions for the treatment of Erythropoietic Protoporphyria. In particular, the present...
2017/0247704 ANTISENSE OLIGONUCLEOTIDES USEFUL IN TREATMENT OF POMPE DISEASE
The present invention is directed to antisense oligomeric compounds that may be used in the treatment Pompe disease as well as method for modulating the...
2017/0247703 ANTIVIRAL NUCLEASE METHODS
Methods and compositions treat a viral infection use a nuclease and an inhibitor that prevents DNA repair, such as a CRISPR-associated nuclease and a small...
2017/0247702 PDGF and VEGF Aptamers Having Improved Stability and Their Use in Treating PDGF and VEGF Mediated Diseases and...
Aptamers having improved stability against nucleases that bind PDGF and aptamers that bind VEGF are provided. In addition, aptamer constructs comprising a PDGF...
2017/0247701 NUCLEIC ACID CAPABLE OF INHIBITING EXPRESSION OF BETA-2GPI
The present invention provides a nucleic acid having activity to suppress expression of .beta.2GPI, a pharmaceutical composition comprising the nucleic acid,...
2017/0247700 NUCLEIC ACID CAPABLE OF INHIBITING EXPRESSION OF BETA-2GPI
The present invention provides a nucleic acid having activity to suppress expression of .beta.2GPI, a pharmaceutical composition comprising the nucleic acid,...
2017/0247699 ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN OR PEPTIDE EXPRESSION
The invention relates to an artificial nucleic acid molecule comprising at least one 5'UTR element which is derived from a TOP gene, at least one open reading...
2017/0247698 INTERFERING RNA MOLECULES
The present invention is related to a ribonucleic acid comprising a double stranded structure whereby the double-stranded structure comprises a first strand...
2017/0247697 INTERFERING RNA MOLECULES
The present invention is related to a ribonucleic acid comprising a double stranded structure whereby the double-stranded structure comprises a first strand...
2017/0247696 MICRORNA WITH PLACENTA-PERMEABILITY AND USES THEREOF
The present invention discloses the use of placenta permeable small RNAs, particularly the use of small ribonucleic acids (small RNAs) in the preparation of a...
2017/0247695 ISOTOPOLOGUES OF SMAD7 ANTISENSE OLIGONUCLEOTIDES
This disclosure relates generally to deuterated isotopologues of SMAD7 antisense oligonucleotides, pharmaceutical compositions containing the same, and methods...
2017/0247694 OLIGONUCLEOTIDE DECOYS FOR THE TREATMENT OF PAIN
Provided are therapeutic agents such as double-stranded nucleic acids, termed oligonucleotide decoys, pharmaceutical compositions comprising the same, and...
2017/0247693 COMBINATORIAL TREATMENT OF CHEMOTHERAPY AND ARMED VIRUSES TARGETING TUMOR
Methods, and kits for inducing cell death in proliferating cells as well as methods of treating cancer, are provided. In some embodiments, the methods comprise...
2017/0247692 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISORDERS
The present disclosure relates to compositions and methods for treating or preventing a neurological disorder.
2017/0247691 INTERFERING RNA MOLECULES
The present invention is related to a ribonucleic acid comprising a double stranded structure whereby the double-stranded structure comprises a first strand...
2017/0247690 ONCOVIRAL TREATMENT WITH NUCLEASE AND CHEMOTHERAPEUTIC
Compositions and methods for treating infection-associated cancer include the use of a nuclease that cuts nucleic acid of an oncovirus in combination with an...
2017/0247689 METHODS AND COMPOSITIONS FOR RAPID NUCLEIC ACID LIBRARY PREPARATION
Rapid nucleic acid libraries, methods of generation, kits, and compositions relating to library synthesis, including reagents, intermediaries and final...
2017/0247688 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES
Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent...
2017/0247687 ERROR DETECTION IN SEQUENCE TAG DIRECTED SUBASSEMBLIES OF SHORT SEQUENCING READS
The invention provides methods for preparing DNA sequencing libraries by assembling short read sequencing data into longer contiguous sequences for genome...
2017/0247686 Single-Molecule Phenotype Analysis
Aspects of the present disclosure include methods of producing modified polypeptides and modified polypeptide-ribosome or polypeptide-mRNA complexes, and...
2017/0247685 DISCOVERING AND PRODUCING CONDITIONALLY ACTIVE BIOLOGIC PROTEINS IN THE SAME EUKARYOTIC CELL PRODUCTION HOSTS
A method of preparing a conditionally active biologic protein by selecting a wild-type biologic protein, evolving the DNA which encodes the wild-type biologic...
2017/0247684 Recombinant Fusion Proteins and Libraries from Immune Cell Repertoires
Disclosed herein are methods and compositions for generating a repertoire of recombinant fusion polypeptides from immune cells, and uses thereof.
2017/0247683 Recombinant Fusion Proteins and Libraries from Immune Cell Repertoires
Disclosed herein are methods and compositions for generating a repertoire of recombinant fusion polypeptides from immune cells, and uses thereof.
2017/0247682 SPECIMEN PRETREATMENT APPARATUS, SPECIMEN PRETREATMENT CARTRIDGE, AND SPECIMEN PRETREATMENT METHOD
Disclosed is a specimen pretreatment apparatus comprising: a specimen container holder configured to hold a specimen container for containing a plasma...
2017/0247681 SOLUTION FOR EXTRACTION OF RNA
A solution for extracting substantially pure RNA from a biological sample is disclosed. The solution for extracting RNA from a biological sample containing RNA...
2017/0247680 Methods of Nucleic Acid Fractionation and Detection
The invention provides methods of detecting a nucleic acid present in a biological sample, comprising combining the biological sample with a lysis buffer to...
2017/0247679 BLENDS CONTAINING PROTEASES
Described are compositions, in particular lyophilizates, containing proteolytic enzymes, and methods for producing the compositions. Typically these...
2017/0247678 INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF...
Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements...
2017/0247677 Compositions and Methods for Modulating Hemostasis
Factor X/Xa variants and methods of use thereof are disclosed.
2017/0247676 COAGULATION FACTOR IX COMPOSITIONS AND METHODS OF MAKING AND USING SAME
The present invention relates to compositions comprising factor IX coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic...
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