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Patent # Description
2017/0252462 EXTENDED ANTEGRADE EPICARDIAL CORONARY INFUSION OF ADENO-ASSOCIATED VIRAL VECTORS FOR GENE THERAPY
The present invention relates to therapies for the treatment of cardiovascular diseases, particularly the delivery of therapeutic agents to heart tissue by...
2017/0252461 HETEROLOGOUS UNTRANSLATED REGIONS FOR MRNA
The invention relates to compositions and methods for the manufacture and optimization of modified mRNA molecules via optimization of their terminal architecture.
2017/0252460 FUNCTIONALIZING NANOFIBRES
Methods for functionalizing the surface of nanofiber substrates, including electrospun fibres and non-woven or woven mats of fibres are described....
2017/0252459 MULTIVALENT FIBRONECTIN-INTEGRIN BINDING COMPOSITIONS AND METHODS OF USE THEREOF
The invention provides multivalent fibronectin-integrin binding compositions and methods of use thereof. In certain embodiments, the invention provides peptide...
2017/0252458 ERIBULIN-BASED ANTIBODY-DRUG CONJUGATES AND METHODS OF USE
Linker toxins and antibody-drug conjugates that bind to human oncology antigen targets such as folate receptor alpha and/or provide anti-tubulin drug activity...
2017/0252457 PROCESS FOR THE PREPARATION OF AN ANTIBODY-RIFAMYCIN CONJUGATE
Processes are described for the preparation of F-benzoxazinorifamycin I: ##STR00001## and intermediates for conjugation with an antibody.
2017/0252456 FUNCTIONAL SEGREGATED TELODENDRIMERS AND NANOCARRIERS AND METHODS OF MAKING AND USING SAME
Provided are multiply functional telodendrimers. The telodendrimers can be used for combination drug delivery. The telodendrimers may have one or more...
2017/0252455 CONJUGATE WITH TARGET-FINDING LIGAND AND USE THEREOF
Described is a conjugate of agent complex and at least one target-finding ligand, where the agent complex comprises an agent encapsulated by an encapsulation...
2017/0252454 Heparosan Polymers and Methods of Making and Using Same for the Enhancement of Therapeutics
Compositions, methods, and systems are disclosed for the development and use of heparosan as a therapeutic modifying agent or vehicle which can modulate drug...
2017/0252453 TRANSMUCOSAL DELIVERY OF PHARMACEUTICAL ACTIVE SUBSTANCES
Provided is a conjugate including a pharmacologically active substance covalently bound to chitosan or its derivative and a method for transmucosal delivery of...
2017/0252452 FILM COATED TABLET FOR THE TREATMENT OF ACUTE PAIN
The invention relates to a film coated tablet for the treatment of acute pain containing 400 mg of ibuprofen, 100 mg of caffeine, 50 to 100 mg of one or more...
2017/0252451 PRESERVATIVE CONTAINING COMPOSITIONS
The present invention relates to compositions providing improved preservative efficacy. The present invention further relates to polyquaternium compound...
2017/0252450 SOLUBILIZED COMPOSITIONS FOR CONTROLLED PROLIFERATION OF STEM CELLS / GENERATING INNER EAR HAIR CELLS USING A...
The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the ...
2017/0252449 SOLUBILIZED COMPOSITIONS FOR CONTROLLED PROLIFERATION OF STEM CELLS / GENERATING INNER EAR HAIR CELLS USING...
The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the ...
2017/0252448 THERMOREVERSIBLE COMPOSITIONS FOR ADMINISTRATION OF THERAPEUTIC AGENTS
The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the ...
2017/0252447 INFUSABLE SOLUTION FOR LOCAL TREATMENT OF BLOOD VESSELS AND VASCULAR GRAFTS AND METHODS OF USING SUCH A SOLUTION
A novel treatment for dialysis patients needing a hemodialysis graft by providing a therapeutic formulation that can be infused to such patients, which may...
2017/0252446 USE OF MESO- AND NANOPOROUS MATERIAL FOR SURFACTANT TRAPPING IN NANOPARTICLE SUSPENSIONS
Disclosed are methods of making stable nanoparticle suspensions wherein one or more nanoporous or mesoporous materials are used to absorb and remove one or...
2017/0252445 TOPICAL ANESTHETIC COMPOSITION
A topical anesthetic composition comprising benzocaine, pharmaceutically acceptable salt thereof, amide thereof and/or ester thereof; tetracaine and/or...
2017/0252444 INTRAUTERINE DEVICE, AND A METHOD OF REDUCING THE RATE OF DIFFUSION OF ACTIVE INGREDIENTS IN SAID INTRAUTERINE...
An intrauterine device having at least one first pharmaceutically active ingredient and at least one first layer made of at least a first polymeric material,...
2017/0252443 METHODS FOR REVERSING MULTIPLE RESISTANCE IN ANIMAL CELLS
The present invention is related to the use of a virus, preferably an adenovirus for reversing resistance in cells.
2017/0252442 PHOTOHEXER COMPOUNDS AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
The present invention relates to photohexer compounds and a pharmaceutical composition and use thereof. Specifically, the present invention relates to ...
2017/0252441 COMPOUND AND METHOD
The present invention provides a method of expressing an antigenic molecule or a part thereof on the surface of a cell using a photochemical internalisation...
2017/0252440 MULTIFUNCTIONAL NANOPARTICLE COMPOSITIONS AND USES THEREOF
Disclosed herein are multifunctional nanoparticle compositions. The compositions can be useful for the treatment of cancer by enhancing the anti-tumor...
2017/0252439 SYSTEM AND METHOD FOR IMPARTING ELECTROMAGNETIC ENERGY INTO WATER AND USE THEREOF
The present invention provides a system for imparting electromagnetic energy into drinking water or aqueous potables and foods, comprising: a generator unit...
2017/0252438 USE OF AN AGENT CONSISTING OF ANTIBODIES AND/OR INSULIN-LIKE GROWTH FACTOR ANTAGONISTS
The present invention relates to the use of a composition selected from the group consisting of antibodies, antibody fragments, insulin-like growth factor...
2017/0252437 PHARMACEUTICAL ANTI-TNF-ALPHA ANTIBODY FORMULATION
Provided are improved storage-stable liquid pharmaceutical antibody formulations. In particular, liquid aqueous pharmaceutical formulations of Adalimumab based...
2017/0252436 LIQUID FORMULATION COMPRISING GM-CSF NEUTRALIZING COMPOUND
The present invention relates to aqueous formulations comprising a compound neutralizing GM-CSF in concentrations of at least 20 mg/ml, a tonicity modifier, a...
2017/0252435 Combination
A pharmaceutical product comprising (a) a conjugation product of TNF and a tumour- or tumour vasculature-targeting peptide comprising an NGR, DGR, isoDGR or...
2017/0252434 COMPOSITIONS FOR IMPROVING THE HEALTH RELATED QUALITY OF LIFE OF RHEUMATOID ARTHRITIS PATIENTS
The present invention provides compositions and methods of for improving the Health-Related Quality of Life of a subject suffering from rheumatoid arthritis,...
2017/0252433 PSMA-RELATED THERAPIES
The present invention provides methods of treating disease by modulation of PSMA activity. Such modulations can lead to, for example, alterations in cancer...
2017/0252432 IMMUNOMODULATORS
The present disclosure provides novel macrocyclic compounds which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for...
2017/0252431 MEDIUM COMPOSITION FOR PREPARING BOTULINUM TOXIN
The present invention relates to a medium composition for production of botulinum toxin and, more particularly, to a medium composition for culture of...
2017/0252430 POLYMERIC CARRIER CARGO COMPLEX FOR USE AS AN IMMUNOSTIMULATING AGENT OR AS AN ADJUVANT
The present invention is directed to a polymeric carrier cargo complex, comprising as a cargo at least one nucleic acid molecule and as a preferably non-toxic...
2017/0252429 Direct Method for providing Immunological Memory against HIV
The disclosed method provides a direct method for creating immunological memory against HIV by educating a patient's naive T and B lymphocytes in vitro into...
2017/0252428 INACTIVATED EQUINE INFLUENZA VIRUS VACCINES
The present invention relates to equine influenza virus (EIV) isolates that when administered in vaccines to equine provide protection against currently...
2017/0252427 FUNCTIONAL INFLUENZA VIRUS-LIKE PARTICLES (VLPS)
The present invention discloses and claims virus like particles (VLPs) that express and/or contains seasonal influenza virus proteins, avian influenza virus...
2017/0252426 Organic Vaccination an alternative method to traditional preventative vaccination
The disclosed method provides an alternative approach of preventative vaccination which consists primarily of extracting and purifying monocytes, naive T and B...
2017/0252425 ZIKA VIRUS VIRUS LIKE PARTICLE
Provided is a virus like particle comprising one or more zika virus structural proteins, and a composition or vaccine comprising thereof, its use in the...
2017/0252424 Methods and compositions for vaccinating a subject for a sexually transmitted pathogen
Purified Chlamydia major outer membrane protein (MOMP) has been observed to induce protection against genital and respiratory challenge in mice. MOMP contains...
2017/0252423 PNEUMOCOCCAL DOSING REGIMEN
Methods of immunizing older adult subjects against Streptococcus pneumoniae infection are provided. Provided methods comprise immunization of naive adult...
2017/0252422 STAGE SPECIFIC DIAGNOSTIC ANTIGENS, ASSAY AND VACCINE FOR LYME DISEASE
Stage-specific Borrelia antigens for diagnosing, treating and/or preventing Lyme disease are provided. The antigens include chimeric Borrelia antigen...
2017/0252421 COMPOUNDS AGAINST RALSTONIA PICKETTII FOR USE IN THE TREATMENT OF INSULIN RESISTANCE, AND METHOD OF DIAGNOSIS...
Compounds disclosed herein are effective against Ralstonia pickettii for treating or preventing insulin resistance, obesity or type II diabetes of a subject,...
2017/0252420 THREE-COMPONENT-MULTISTAGE MALARIA VACCINE
The technology provided herein relates to novel malaria vaccines composed of different recombinant proteins, in particular recombinant fusion proteins...
2017/0252419 Genetic Attenuation of Plasmodium by B9 Gene Disruption
Disclosed herein are mutant Plasmodium-species parasites that are genetically attenuated (GAP). They retain the ability to infect a host and invade host...
2017/0252418 GENETICALLY MODIFIED COCCIDIAN PARASITES USEFUL AS VACCINES
A genetically modified coccidian parasites wherein expression of phosphatidylthreonine synthase (PTS) is disrupted, a polynucleotide including a nucleotide...
2017/0252417 PROTEIN-CHAPERONED T-CELL VACCINES
Protein antigens are provided. The protein antigens typically include a peptide antigen conjugated or fused to a chaperone protein to form a ...
2017/0252416 TREATMENT OF DISEASE USING INTER-ALPHA INHIBITOR PROTEINS
The invention relates to methods of treatment of medical conditions (e.g., diseases and injuries) in a mammal (e.g., a human), such as hypoxia/ischemia, burns,...
2017/0252415 Botulinum Toxin and the Treatment of Primary Disorders of Mood and Affect
A method of treating circadian rhythm disorders includes identifying a subject with a circadian rhythm disorder or at least one symptom of a circadian rhythm...
2017/0252414 Compositions and Methods for Treating Pathological Calcification and Ossification
The present invention includes compositions and methods for treating disease and disorders associated with pathological calcification or pathological...
2017/0252413 NANO-SCALE DELIVERY DEVICE AND USES THEREOF
Disclosed is a delivery device for delivering a payload, including a biological, chemical or biochemical substance, to a subject. The delivery device has a...
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