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Patent # Description
2017/0253681 MATERIAL FOR 3D PRINTING, PROCESS FOR PREPARING THE SAME AND ARTICLE THEREOF
The present invention provides a composition for 3D printing, a process for preparing the same and an article thereof. By the solidifying method of UV...
2017/0253680 ACTIVE-ENERGY-RAY-CURABLE COMPOSITION, CURED MATERIAL, COMPOSITION STORED CONTAINER, TWO-DIMENSIONAL OR...
An active-energy-ray-curable composition including: polymerizable monomer (A1) containing one (meth)acryloyl group; acylphosphine oxide-based polymerization...
2017/0253679 HIGHLY SELECTIVE POLYNORBORNENE HOMOPOLYMER MEMBRANES FOR NATURAL GAS UPGRADING
Embodiments for a crosslinked alkoxysilyl polynorbornene homopolymer and methods of making crosslinked alkoxysilyl polynorbornene homopolymer are provided,...
2017/0253678 VINYLIDENE FLUORIDE POLYMERS
The present invention pertains to a process for manufacturing a vinylidene fluoride polymer, to a polymer obtainable via said process and to an article...
2017/0253677 Support Material Having an Hourglass Shape
A support material having an hourglass shape reduces the cost of manufacturing as well as increasing comfort and air circulation. The support material includes...
2017/0253676 Catalyst Systems and Methods of Making and Using the Same
Olefin polymerization catalyst systems and methods for making and using the same are provided.
2017/0253675 PRESSURE SENSITIVE ADHESIVE INCLUDING A 1,1-DISUBSTITUTED ALKENE COMPOUND
The present teachings show that it is possible to polymerize 1,1-disubstituted alkene compounds in a solution (for example using one or more solvents)....
2017/0253674 Cellulose ethers substituted with hydroxyl and alkyne groups and with hydroxyalkyl, alkyne and azide groups,...
Nonionic, water-soluble cellulose ethers are disclosed with hydroxyalkyl groups and .omega.-alkynyl groups, each joined to the cellulose via an ether bond, the...
2017/0253673 STIMULI-RESPONSIVE PROTEIN-POLYMER CONJUGATES FOR BIOSEPARATION
There are provided efficient and cost-effective methods for purifying biomolecules in solution phase using stimuli-responsive protein-polymer conjugates. The...
2017/0253672 REMOVAL OF MONOMERIC TARGETS
The present invention relates to a novel method for the removal of monomeric targets from bodily fluids, and to pharmaceutical compositions for use in such...
2017/0253671 Expression Constructs and Methods for Expressing Polypeptides in Eukaryotic Cells
The invention relates to an expression construct for the expression of polypeptides in host cells using alternative splicing. The expression construct can be...
2017/0253670 COMMON LIGHT CHAINS AND METHODS OF USE
The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells...
2017/0253669 NOVEL ANTI-HUMAN TIE-2 ANTIBODY
Provided is an anti-human Tie2 antibody for preventing or treating diabetic macular edema, diabetic retinopathy, and critical limb ischemia by binding to a...
2017/0253668 THERAPEUTIC AND DIAGNOSTIC ANTI-LOXL4 ANTIBODIES
Provided are methods and compositions for the detection, prevention and treatment of primary and metastatic neoplastic diseases, including, but not limited to,...
2017/0253667 METHODS FOR INHIBITING FIBROSIS IN A SUBJECT IN NEED THEREOF
In one aspect, the invention provides methods for treating, inhibiting, alleviating or preventing fibrosis in a mammalian subject suffering, or at risk of...
2017/0253666 Methods for Treating Patients with Hyperlipidemia by Administering a PCSK9 Inhibitor in Combination with an...
The present invention provides methods for treating patients suffering from hypercholesterolemia, wherein the patient is non-responsive to, inadequately...
2017/0253665 ANTIBODIES AGAINST CD73
The present invention provides isolated monoclonal antibodies, particularly human antibodies, that bind to human Cluster of Differentiation 73 (CD73) with high...
2017/0253664 DUAL TARGETING OF TAFI AND PAI-1
Disclosed herein is a bispecific inhibitor for use in treating thrombotic disorders, such as acute thrombotic disorders like stroke and thromboembolism. The...
2017/0253663 METHODS FOR TREATING A DISEASE THAT DEVELOPS OR PROGRESSES AS A RESULT OF DECREASE OR LOSS OF ACTIVITY OF BLOOD...
The inventors discovered that by administering a pharmaceutical composition comprising a bispecific antigen-binding molecule that recognizes blood coagulation...
2017/0253662 DOSAGE AND ADMINISTRATION OF ANTI-EGFR THERAPEUTICS
Methods for optimizing a therapeutic response in a patient (e.g., a cancer patient) to an anti-EGFR therapy, and methods for preventing or ameliorating...
2017/0253661 GALACTOENGINEERED IMMUNOGLOBULIN 1 ANTIBODIES
The present invention relates to galactoengineered recombinant antibodies of IgG1 isotype, methods for the production of said antibodies and uses thereof.
2017/0253660 ANTI-GD2 ANTIBODIES
In this application are described chimeric, humanized, affinity matured, stability enhanced, and bispecific Anti-GD2 antibodies and fragments thereof. Also...
2017/0253659 ANTIBODIES TO CD40 WITH ENHANCED AGONIST ACTIVITY
Provided herein are agonistic antibodies, or antigen binding portions thereof, that bind to human CD40. Such antibodies optionally comprise Fc regions with...
2017/0253658 CD94/NKG2A AND/OR CD94/NKG2B ANTIBODY, VACCINE COMBINATIONS
The disclosure provides among others a combination of a vaccine and a CD94/NKG2A and/or a CD94/NKG2B binding antibody for use in the treatment of a subject in...
2017/0253657 MODULATION OF LEUKOCYTE ACTIVITY IN TREATMENT OF NEUROINFLAMMATORY DEGENERATIVE DISEASE
Methods for treating and reducing the progression of neurodegenerative diseases, including, without limitation Alzheimer's disease, are provided. The methods...
2017/0253656 ANTI-CD74 ANTIBODIES, COMPOSITIONS COMPRISING ANTI-CD74 ANTIBODIES AND METHODS OF USING ANTI-CD74 ANTIBODIES
Provided herein are antibodies that selectively bind to CD74 and its isoforms and homologs, and compositions comprising the antibodies. Also provided are...
2017/0253655 LOW DOSE IMMUNE CHECKPOINT BLOCKADE IN METASTATIC CANCER
A method of treating cancer comprising and reducing autoimmune side effects in administration of anti-CTLA-4 antibodies. The invention provides methods for low...
2017/0253654 ANTI-PD-L1 ANTIBODIES AND USES THEREOF
The present application relates to anti-PD-L1 antibodies or antigen binding fragments thereof, nucleic acid encoding the same, therapeutic compositions...
2017/0253653 ANTI-PD-L1 ANTIBODIES AND USES THEREOF
The present application relates to anti-PD-L1 antibodies or antigen binding fragments thereof, nucleic acid encoding the same, therapeutic compositions...
2017/0253652 INHIBITION OF BONE RESORPTION WITH RANKL BINDING PEPTIDES
Methods are provided for inhibiting bone resorption and/or osteoclast activity. More specifically, methods are provided wherein polypeptides against RANK-L are...
2017/0253651 Methods of Suppressing Rheumatoid Arthritis Using An Anti-IL-6 Antibody
Anti-IL-6 antibodies and antirheumatics are useful to treat and suppress IL-6 related conditions, such as rheumatoid arthritis.
2017/0253650 ANTI-PARASITIC COMPLEXES
The technology provided herein relates to novel anti-parasitic complexes, in particular recombinant fusion proteins suitable as human and/or animal drugs...
2017/0253649 TREATMENT OF TAUOPATHIES
The invention is directed to methods of treatment of Alzheimer's disease and other tauopathies, via the administration of antibodies having specificity to...
2017/0253648 Compositions and Methods for Prophylaxis and/or Therapy of Disorders that Correlate with DENND1A Variant 2
Pharmaceutical compositions and methods for the treatment of DENND1A.V2 related disorders, such as PCOS, are provided. In particular, humanized and mouse...
2017/0253647 BIOMIMETIC POLYMERS FOR THE PREVENTION AND TREATMENT OF VIRAL DISEASES
Antiviral biomimetic polymers (ABPs) are disclosed that can be used to prevent and/or treat viral disease. The ABPs are discovered by a process involving...
2017/0253646 Functional Peptide Analogs of PEDF
The invention provides compositions and methods relating to bioactive peptide analogs of PEDF.
2017/0253645 UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES
Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of...
2017/0253644 BINDING DOMAINS DIRECTED AGAINST GPCR:G PROTEIN COMPLEXES AND USES DERIVED THEREOF
The present disclosure relates to the field of G protein coupled receptor (GPCR) structural biology and signaling. In particular, the present disclosure...
2017/0253643 Centrally-Acting Peptide Derivative, and Pharmaceutical Composition
A centrally-acting peptide derivative, including a centrally-acting portion, a cell-penetrating sequence portion, and an endosomal-escape portion.
2017/0253642 Platelet-Derived Growth Factor B Mutant, Preparation Method Therefor and Use Thereof
Provided are a platelet-derived growth factor B derivative, the encoding nucleic acid molecule thereof, and a vector and host cell having the nucleic acid...
2017/0253641 Medicament for Atrophy Treatment or Increasing Cell Growth
The present invention provides SERF2, a nucleic acid encoding said SERF2 or a cell expressing SERF2 for use as a medicament, in particular for use for use in...
2017/0253640 CLEAVAGE RESISTANT PHOTOLUMINESCENT PROTEINS AND APPLICATIONS THEREOF
Photoluminescent proteins resistant to protein cleavage reagents are described herein. In being resistant to cleavage reagents, such photoluminesncent proteins...
2017/0253639 Nutritive Fragments, Proteins and Methods
Nutritive proteins are provided. In some embodiments the nutritive proteins comprise a first polypeptide sequence comprising a fragment of a ...
2017/0253638 ANITMICROBIAL PEPTIDE PRODUCED BY INTESTINAL LACTOBACILLUS SALIVARIUS
An antimicrobial peptide having potent antibacterial activity against Listeria monocytogenes and Staphylococcus aureus is described. Also described is an...
2017/0253637 SIGNAL PEPTIDE FUSION PARTNERS FACILITATING LISTERIAL EXPRESSION OF ANTIGENIC SEQUENCES AND METHODS OF...
The present invention provides nucleic acids, expression systems, and vaccine strains which provide efficient expression and secretion of antigens of interest...
2017/0253636 Dual Purpose Universal Influenza Vaccine Confers Protective Immunity Against Anthrax
The present invention includes antigenic fusion proteins, nucleic acids encoding the fusion proteins and methods of making and using the same, wherein the...
2017/0253635 ANTIFUNGAL AGENTS AND USES THEREOF
The invention features echinocandin class compounds. The compounds can be useful for the treatment of fungal infections.
2017/0253634 BETA-HAIRPIN PEPTIDOMIMETICS
Beta-hairpin peptidomimetics of the general formula (I), cyclo[P.sup.1-P.sup.2-P.sup.3-P.sup.4-P.sup.5-P.sup.6-P.sup.7-P.sup.8-P.s- ...
2017/0253633 PEPTIDES, COMBINATION OF PEPTIDES, AND CELL BASED MEDICAMENTS FOR USE IN IMMUNOTHERAPY AGAINST URINARY BLADDER...
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2017/0253632 INHIBITION OF PULMONARY FIBROSIS WITH NUTLIN-3A AND PEPTIDES
In fibrotic lung fibroblasts, basal levels of p53 protein (and miR-34a) are markedly suppressed, leading to reduced p53-mediated inhibition of uPA and uPAR, or...
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