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| Patent # | Description |
|---|---|
| 2017/0258804 |
METHODS FOR TREATING CANCERS Disclosed are methods for treating a cancer in a subject (e.g., a human) in need thereof, comprising administering to the subject a therapeutically effective... |
| 2017/0258803 |
SALTS AND SOLID FORMS OF
(S)-3-(4-((4-(MORPHOLINOMETHYL)BENZYL)OXY)-1-OXOISOINDOLIN-2-YL)PIPERIDIN-
... Salts and solid forms of 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,- 6-dione, or a stereoisomer thereof, are disclosed.... |
| 2017/0258802 |
METHOD OF TREATING POLYCYSTIC KIDNEY DISEASES WITH CERAMIDE DERIVATIVES A method of treating polycystic kidney disease in a subject comprises administering to the subject an effective amount of a compound represented by Structural... |
| 2017/0258800 |
SALTS OF 2-FLUORO-N-METHYL-4-[7-(QUINOLIN-6-YL-METHYL)-
IMIDAZO[1,2-B][1,2,4]TRIAZIN-2-YL]BENZAMIDE AND... The present invention is directed to dihydrochloric acid and dibenzenesulfonic acid salts of the c-Met kinase inhibitor ... |
| 2017/0258799 |
CAFFEINATED GUMMIES Described herein are gummy compositions and products. In one aspect the gummy compositions include: (I) one or more gelating agents; (II) at least one fruit... |
| 2017/0258798 |
INJECTION PREPARATION AND METHOD FOR PRODUCING SAME Provided are an injection preparation which include: an aqueous composition containing pemetrexed or a salt thereof, at least one antioxidant agent which is... |
| 2017/0258797 |
TREATMENTS FOR AUTOIMMUNE DISEASE The invention relates to a novel approach to the treatment of autoimmune diseases, particularly multiple sclerosis. In a further embodiment of the invention... |
| 2017/0258796 |
Methods And Compositions To Reduce Oxidative Stress The invention relates to therapeutic applications for compositions that reduce the level of oxidative stress on cells in vivo or in vitro. The invention... |
| 2017/0258795 |
FUSED PYRIMIDINES AS INHIBITORS OF P97 COMPLEX Fused pyrimidine compounds having a saturated, unsaturated or aromatic A ring fused to a pyrimidine ring and having a complex substituents at the 2 position... |
| 2017/0258794 |
PRODRUGS OF AMINO QUINAZOLINE KINASE INHIBITOR Disclosed are compounds having the formula: ##STR00001## wherein X is as defined herein, and methods of making and using the same. |
| 2017/0258793 |
METHOD FOR TREATING PROSTATE CANCER The invention provides a method for treating prostate cancer in a subject comprising administering to the subject an effective amount of a selective inhibitor... |
| 2017/0258792 |
LIGANDS THAT TARGET PLASMODIUM SPOROZOITE BINDING SITES ON CD81 AND
THERAPEUTIC METHODS USING THEM The invention pertains to ligands that bind to CD81 and that inhibit or block Plasmodium attachment to CD81, compositions and methods for preventing,... |
| 2017/0258791 |
PHARMACEUTICAL COMPOSITION FORMED BY COMBINING PYRIDOXAMINE COMPOUND AND
THIAMINE COMPOUND Vitamin B1 deficiency caused when a pyridoxamine compound is administered in a large amount is prevented and/or treated. A pharmaceutical composition formed by... |
| 2017/0258790 |
Methods Of Treating Depression Using Orexin-2 Receptor Antagonists The present disclosure is directed to, inter alia, methods of treating a subject suffering from or diagnosed with depression, comprising administering to a... |
| 2017/0258789 |
DNA-PK INHIBITORS The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said... |
| 2017/0258788 |
CARBOSTYRIL DERIVATIVES AND SEROTONIN REUPTAKE INHIBITORS FOR TREATMENT OF
MOOD DISORDERS The pharmaceutical composition of the present invention comprises (1) a carbostyril derivative and (2) a serotonin reuptake inhibitor in a pharmaceutically... |
| 2017/0258787 |
PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR BEHAVIORAL AND PSYCHOLOGICAL
SYMPTOMS ASSOCIATED WITH... The present invention relates to a prophylactic and/or therapeutic agent for behavioral and psychological symptoms associated with neurodegenerative disease or... |
| 2017/0258786 |
RBP4 ANTAGONISTS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND
STARGARDT DISEASE A method for treating a disease characterized by excessive lipofuscin accumulation in the retina in a mammal afflicted therewith, comprising administering to... |
| 2017/0258785 |
COMPOSITE NANOPARTICLES AND USES THEREOF Provided herein are composite nanoparticles, methods of making composite nanoparticles and methods of using composite nanoparticles to treat or ameliorate... |
| 2017/0258784 |
USE OF PYRROLOQUINOLINE COMPOUNDS TO KILL CLINICALLY LATENT MICROORGANISMS There is provided the use of compounds of formula I ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3 and X have meanings given in the description, for the... |
| 2017/0258783 |
PFKFB3 INHIBIT AND METHODS OF USE AS AN ANTI-CANCER THERAPEUTIC A novel compound, (E)-1-(pyridyn-4-yl)-3-(7-(trifluoromethyl)quinolin-2-yl)-prop-2-en-1-one- , is provided herein. ... |
| 2017/0258782 |
ALKYL LINKED QUINOLINYL MODULATORS OF ROR.gamma.t The present invention comprises compounds of Formula I. ##STR00001## wherein: R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, and... |
| 2017/0258781 |
ATRIAL SPECIFIC ANTIARRHYTHMICS FOR USE IN TREATING OR PREVENTING ATRIAL
FIBRILLATION The invention relates to methods and compositions for treating or preventing atrial fibrillation. |
| 2017/0258780 |
TREATMENT OF LUPUS NEPHRITIS USING LAQUINIMOD This invention provides a method of treating a subject afflicted with active lupus nephritis comprising periodically administering to the subject an amount of... |
| 2017/0258779 |
COMBINATION THERAPY FOR BIPOLAR DISORDER The present invention relates to a method of decreasing cholesterol or low density lipid protein in a subject in need thereof comprising: administering to said... |
| 2017/0258778 |
SOLID FORMS COMPRISING
4-AMINO-2-(2,6-DIOXOPIPERIDINE-3-YL)ISOINDOLINE-1,3-DIONE AND A COFORMER,
... Provided herein are solid forms comprising (a) 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione and (b) a coformer. Pharmaceutical compositions... |
| 2017/0258777 |
Selective NR2B Antagonists The disclosure generally relates to compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds... |
| 2017/0258776 |
Methods for Treating Disorders or Diseases Associated with Hyperlipidemia
and Hypercholesterolemia While... The present invention provides methods and compositions for treating hyperlipidemia and/or hypercholesterolemia comprising administering to the subject an... |
| 2017/0258775 |
MULTISUBSTITUTED AROMATIC COMPOUNDS AS SERINE PROTEASE INHIBITORS There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or... |
| 2017/0258774 |
NOVEL OXIMES FOR REACTIVATING BUTYRYLCHOLINESTERASE Oxime molecules for reactivating butyrylcholinesterase (BChE) and methods for protection against and therapeutic treatment of the toxic effects of ... |
| 2017/0258773 |
SOLID FORMS OF ACETIC ACID, COMPOSITIONS, AND USES THEREOF Provided herein are solid forms comprising {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions comprising the solid forms,... |
| 2017/0258772 |
COMPOSITIONS AND METHODS FOR PROMOTING INTESTINAL STEM CELL AND/OR
NON-STEM PROGENITOR CELL FUNCTION Disclosed herein are novel methods and compositions useful for promoting intestinal stem cell function. The methods and compositions are particularly useful... |
| 2017/0258771 |
Compositions and Methods of Treating Cardiac Fibrosis with Ifetroban The present invention is directed to methods of treating, preventing, and/or ameliorating fibrosis syndrome, and in particular cardiac fibrosis, by... |
| 2017/0258770 |
Method for Topically Treating Actinic Keratosis on the Full Face or 250
cm2 on the Chest with Ingenol... The invention relates to the treatment of actinic keratosis on the full face or 250 cm.sup.2 on the chest with ingenol 3-(3,5-diethylisoxazole-4-carboxylate). |
| 2017/0258769 |
A Method for Topically Treating Actinic Keratosis on the Trunk (except
chest) and Extremities with Ingenol
... The invention relates to the treatment of actinic keratosis on the trunk (except chest) and extremities with ingenol 3-(3,5-diethylisoxazole-4-carboxylate). |
| 2017/0258768 |
ONDANSETRON EXTENDED RELEASE SOLID DOSAGE FORMS FOR TREATING EITHER
NAUSEA, VOMITING OR DIARRHEA SYMPTOMS A method of treating a patient comprises orally administering a solid oral dosage form comprising a core comprising a non-ionic polymer matrix, a first amount... |
| 2017/0258767 |
METHODS FOR THE TREATMENT OF OVERACTIVE BLADDER Disclosed herein are methods of treating overactive bladder in a patient, the method comprising identifying a patient in need thereof; and administering to the... |
| 2017/0258766 |
ANGIOTENSIN IN TREATING BRAIN CONDITIONS The present invention provides, among other things, methods and compositions for treating brain conditions. In some embodiments, the methods include... |
| 2017/0258765 |
Priming of Pancreatic Tumor Cells and Cancer Stem Cells to TRAIL-Induced
Apoptosis This invention relates generally to compositions and methods for treatment of pancreatic cancer. The present invention relates more particularly to use of JNK... |
| 2017/0258764 |
NITROGEN-CONTAINING HETEROCYCLIC COMPOUND The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as an agent for the... |
| 2017/0258763 |
RAPID DISPERSE DOSAGE FORM A high dose rapidly dispersing three-dimensionally printed dosage form comprising a high dose of water soluble drug in a porous matrix that disperses in water... |
| 2017/0258762 |
FORMULATION COMPRISING GLYCOPYRROLATE, METHOD AND APPARATUS A method is disclosed for making a pharmaceutical composition for pulmonary administration comprising co-jet milling glycopyrrolate and magnesium stearate,... |
| 2017/0258761 |
Pharmaceutical Compositions Comprising Canagliflozin The present invention belongs to the field of pharmaceutical industry and relates to a dry pharmaceutical composition comprising Canagliflozin, as well as to a... |
| 2017/0258760 |
TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 8 (TRPM8)
ANTAGONISTS AND METHODS OF USE The invention provides methods of treating or preventing an ocular disease or disorder in a subject, methods of treating or preventing ocular pain or... |
| 2017/0258759 |
METHOD OF IMPROVING VISUAL PROCESSING, VISUAL ACUITY, OR BOTH BY
ADMINISTERING COMPOSITIONS COMPRISING... Methods for improving the visual processing of a healthy infant by administering a composition comprising RRR-alpha-tocopherol and a carotenoid to the infant... |
| 2017/0258758 |
METHODS FOR TREATING BRAIN METASTASIS The present invention relates to methods for treating brain metastasis by inhibiting gap junction functionality. It is based, at least in part, on the... |
| 2017/0258757 |
ANTI-CANCER AGENT DELIVERY VEHICLES CAPABLE OF IMPROVED LOADING There is provided a conjugate of a delivery agent containing a chemical moiety and at least one flavonoid. The flavonoid exists in a monomeric form or dimeric... |
| 2017/0258755 |
METHODS OF REDUCING THE RISK OF A CARDIOVASCULAR EVENT IN A SUBJECT ON
STATIN THERAPY In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in... |
| 2017/0258754 |
METHODS OF REDUCING THE RISK OF A CARDIOVASCULAR EVENT IN A SUBJECT ON
STATIN THERAPY In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in... |
| 2017/0258753 |
METHODS OF REDUCING THE RISK OF A CARDIOVASCULAR EVENT IN A SUBJECT ON
STATIN THERAPY In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in... |
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