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Patent # Description
2017/0292161 METHODS AND COMPOSITIONS FOR DETECTING COLORECTAL NEOPLASIAS USING MICRO RNAs
Methods of detecting or predicting the presence of colorectal neoplasia are described based on the amounts of particular miRNAs in plasma.
2017/0292160 Methods for Diagnosing and Treating Eye-Length Related Disorders
The invention provides to methods for diagnosing eye-length related disorders, including myopia. The invention also provides methods for treating and limiting...
2017/0292159 GENETIC POLYMORPHISMS ASSOCIATED WITH CARDIOVASCULAR DISEASES, METHODS OF DETECTION AND USES THEREOF
The present invention provides compositions and methods based on genetic polymorphisms that are associated with cardiovascular diseases, particularly coronary...
2017/0292158 METHODS, COMPOSITIONS, AND KITS COMPRISING LINKER PROBES FOR QUANTIFYING POLYNUCLEOTIDES
The present invention is directed to methods, reagents, kits, and compositions for identifying and quantifying target polynucleotide sequences. A linker probe...
2017/0292157 METHODS AND COMPOSITIONS FOR EFFICIENT BASE CALLING IN SEQUENCING REACTIONS
The present invention is directed to methods and compositions for acquiring nucleotide sequence information of target sequences. In particular, the present...
2017/0292156 MODIFIED PROTEINS AND METHODS OF MAKING AND USING SAME
Methods, compositions, systems, apparatuses and kits comprising modified proteins, particularly modified nucleic acid-binding proteins with altered buffering...
2017/0292155 METHODS AND COMPOSITIONS FOR IDENTIFYING REPEATING SEQUENCES IN NUCLEIC ACIDS
Short Tandem Repeats are currently used by law enforcement and others, for example, for the identification of individuals by DNA matching. A method is...
2017/0292154 Methods For Determining Biological States By Assessing Amounts Of Target Nucleic Acids In A Sample
Described herein are compositions for evaluating nucleic acids, standardized mixture for assessing amounts of at least one target nucleic acid in a sample, and...
2017/0292153 METHOD FOR BREAKING NUCLEIC ACID AND ADDING ADAPTOR BY MEANS OF TRANSPOSASE, AND REAGENT
Provided are a method for breaking a nucleic acid and adding an adaptor by means of a transposase, and a reagent. The method comprises the following steps:...
2017/0292152 SYSTEMS AND METHODS FOR SAMPLING OF AMPLIFICATION PRODUCTS
The invention provides systems and methods for processing samples. In a method, a reaction card is provided that has a channel network, a valve, and a...
2017/0292151 METHOD AND SYSTEM FOR SAMPLE PREPARATION
A disposable cartridge for preparing a nucleic acid sample including a stationary cartridge body and a cylindrical rotor rotationally mounted to the cartridge...
2017/0292150 PROBES FOR IMAGING HUNTINGTIN PROTEIN
Provided are imaging agents comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and methods of their use. ##STR00001##
2017/0292149 METHODS USING RANDOMER-CONTAINING SYNTHETIC MOLECULES
Methods are provided for correction of amplification bias and quantitation of adaptive immune cells in a sample using synthetic templates that include random...
2017/0292148 DETECTION OF BACTERIAL (MOLLICUTES) CONTAMINATION
The present disclosure provides a method and system for the PCR amplification of a target sequence which suppresses non-specific amplification products. The...
2017/0292147 HAPLOTYPE RESOLVED GENOME SEQUENCING
Methods of determining a haplotype or partial haplotype of a DNA sample containing high molecular weight segments of genomic DNA are disclosed. Such methods...
2017/0292146 METHODS AND DEVICES FOR DETECTING AND IDENTIFYING MICROORGANISMS
Methods and devices for isolating microbial cells from a sample, extracting eukaryotic DNA from a sample, and identifying the microbial species in the sample...
2017/0292145 QUALITATIVE AND QUANTITATIVE DETECTION OF MICROBIAL NUCLEIC ACIDS
The present invention relates to new methods and uses for the qualitative and quantitative detection of microbial nucleic acids using at least a first control...
2017/0292144 COMPOSITIONS, METHODS, AND KITS FOR SYNTHESIS AND DETECTION OF NUCLEIC ACIDS
Compositions, methods, and kits for synthesizing, detecting, and/or quantifying nucleic acids are provided herein. Embodiments comprise a nucleic acid...
2017/0292143 Phenotypic engineering of spores
The biological functionality of living microbial spores is modified using phenotypic engineering to endow the resulting modified spores with novel ...
2017/0292142 Rapid Detection of Bacteria using Mass Spectrometric Analysis
Methods for the detection or diagnosis of a bacterial infection or colonisation utilising mass spectrometric analysis are provided. The methods involve...
2017/0292141 PROCESSES USING AMINO ACID DEHYDROGENASES AND KETOREDUCTASE-BASED COFACTOR REGENERATING SYSTEM
The present disclosure relates to the use of an amino acid dehydrogenase in combination with a cofactor regenerating system comprising a ketoreductase. In...
2017/0292140 METHOD FOR PURIFYING TARGET PROTEIN
Disclosed is a method for purifying a target protein, comprising steps of: bringing a fusion protein containing an amino acid sequence of a peptide tag, an...
2017/0292139 GENETICALLY EXPANDED CELL FREE PROTEIN SYNTHESIS SYSTEMS, METHODS AND KITS
This invention relates to methods of producing a rare amino acid- or non-natural amino acid-containing protein in a cell free protein synthesis system and kits...
2017/0292138 CELL-FREE PRODUCTION OF RIBONUCLEIC ACID
Provided herein, in some aspects, are methods and compositions for cell-free production of ribonucleic acid.
2017/0292137 COMPOSITION AND METHOD FOR PROCESSING DNA
A method of cleaving DNA molecules into smaller fragments by the creation of "cleavage trigger sites" followed by enzymatic processing. In some embodiments the...
2017/0292136 Cellobiohydrolase Variants And Polynucleotides Encoding Same
The present invention relates to cellobiohydrolase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid...
2017/0292134 VARIANT MICROORGANISM PRODUCING 5-AMINOLEVULINIC ACID AND METHOD FOR PREPARING 5-AMINOLEVULINIC ACID USING THEREOF
The present invention relates to a mutant microorganism having the ability to produce 5-aminolevulinic acid, and more particularly, to a mutant microorganism...
2017/0292133 PREPARATION OF LACTIC ACID AND/OR A LACTATE SALT FROM LIGNOCELLULOSIC MATERIAL BY SEPARATE SACCHARIFICATION AND...
A process for preparing lactic acid and/or a lactate salt via the fermentation of carbohydrates obtained from lignocellulosic material. In particular the...
2017/0292132 TISSUE PREFERENTIAL CODON MODIFIED EXPRESSION CASSETTES, VECTORS CONTAINING SAME, AND USES THEREOF
Described herein are synonymously altered gene sequences which express protein in differing levels within secretory as compared to non-secretory target tissue....
2017/0292131 Genes and uses for plant improvement
Transgenic seed for crops with improved traits are provided by trait-improving recombinant DNA where plants grown from such transgenic seed exhibit one or more...
2017/0292130 HEAT-TOLERANT TOMATO MUTANT AND METHOD FOR PRODUCING THE SAME
A heat-tolerant tomato plant exhibiting a high capacity for developing seed-containing fruits under high temperature conditions is provided. The present...
2017/0292129 TREATMENT OF C9FTD/ALS BY TARGETING RNA EXPANDED REPEAT SEQUENCES
A repeat expansion in C90RF72 causes frontotemporal dementia and amyotrophic lateral sclerosis (c9FTD/ALS). RNA of the expanded repeat (r(GGGGCC).sub.exp)...
2017/0292128 METHOD FOR SELECTIVELY INHIBITING ACAT1 IN THE TREATMENT OF NEURODEGENERATIVE DISEASES
The present invention features methods for stimulating clearance of misfolded or aggregated proteins or peptides in microglia or neurons, and treating...
2017/0292127 COMPOSITIONS AND METHODS FOR MODULATING AN IMMUNE RESPONSE
The disclosure relates to, among other things, agents that modulate the homophilic interaction between two CRACC polypeptides, methods for making such agents,...
2017/0292126 NEUROPROTECTIVE MOLECULES AND METHODS OF TREATING NEUROLOGICAL DISORDERS AND INDUCING STRESS GRANULES
Provided herein are neuroprotective molecules containing a sequence of 25-35 contiguous nucleotides that is at least 80% identical to a contiguous sequence...
2017/0292125 MULTIPLE EXON SKIPPING COMPOSITIONS FOR DMD
Provided are antisense molecules capable of binding to a selected target site in the human dystrophin gene to induce exon skipping, and methods of use thereof...
2017/0292124 METHODS AND SYSTEMS FOR CONSTRUCTION OF NORMALIZED NUCLEIC ACID LIBRARIES
The present disclosure generally relates to nucleic acid amplification systems and methods suitable for construction of nucleic acid samples, including...
2017/0292123 DEVICE FOR PURIFYING NUCLEIC ACIDS
The invention relates to a device (1) for purifying nucleic acids composed of a one-piece hollow body (2) comprising an upper portion (3) having an inlet port...
2017/0292122 PURIFICATION OF NUCLEIC ACID FROM A SAMPLE CONTAINING NUCLEIC ACID AND ENDOTOXIN
A process for purifying nucleic acids, especially plasmid DNA, from a nucleic acid-containing, biologic sample, consisting of the following steps: a)...
2017/0292121 METHODS AND COMPOSITIONS RELATED TO THIOESTERASE ENZYMES
The present invention relates to novel mutant thioesterase enzymes and naturally-occurring equivalents thereof, compositions made from such enzymes and uses of...
2017/0292120 MICROBIAL PRODUCTION OF ALKANOLAMIDES AND AMIDOAMINES AND USES THEREOF
The disclosure relates to a recombinant microorganism engineered to express an enzyme which catalyzes the conversion of a primary amine and an acyl thioester...
2017/0292119 PICHINDE VIRUS REVERSE GENETICS SYSTEMS AND METHODS OF USE
Provided herein are genetically engineered Pichinde viruses that include three ambisense genomic segments. The first genomic segment includes a coding region...
2017/0292118 METHOD FOR MODULATING CAR-INDUCED IMMUNE CELLS ACTIVITY
The present invention relates to a method to modulate the level of activation of an engineered immune cell (such as a Chimeric Antigen Receptor T-cell) for...
2017/0292117 A HUMAN LIVER MICROPHYSIOLOGY PLATFORM AND SELF ASSEMBLY LIVER ACINUS MODEL AND METHODS OF THEIR USE
Microfluidic devices for modeling three-dimensional tissue structures and methods for making and using the same are described herein.
2017/0292116 IN VIVO MODEL OF HUMAN SMALL INTESTINE USING PLURIPOTENT STEM CELLS AND METHODS OF MAKING AND USING SAME
Disclosed are methods for making a vascularized hollow organ derived from human intestinal organoid (HIOs). The HIOs may be obtained from human embryonic stem...
2017/0292115 PROTEINS INCREASING PANCREATIC BETA CELL NUMBER AND METHODS OF USE
Disclosed herein are bacterial proteins that increase pancreatic beta (.beta.) cell number and/or proliferation, methods of increasing .beta. cell number...
2017/0292114 A METHOD OF INDUCING BONE FORMATION BY EX-VIVO OSTEOBLAST CULTURING FOR IMPLANTATION
An ex-vivo culturing method of osteoblasts for implantation, comprising a culturing of adult live osteoblasts as an ex-vivo procedure. The ex-vivo culture,...
2017/0292113 INFLAMMATION-TARGETED NEUTROPHIL GRANULOCYTE DRUG DELIVERY SYSTEM AND USE THEREOF
Disclosed are an inflammation-targeted neutrophil granulocyte drug delivery system and use thereof, wherein the drug delivery system includes neutrophil...
2017/0292112 COMPOSITION AND METHOD FOR DIFFERENTIATION OF NEURAL STEM CELLS, NEURONS AND GABAERGIC NEURONS FROM MESENCHYMAL...
A method for differentiation of neural stem cells, neurons and GABAergic neurons from mesenchymal stem cells includes culturing the mesenchymal stem cells in a...
2017/0292111 USE OF BMP4 FOR THYMIC REGENERATION
The present disclosure describes methods to promote thymic regeneration following injury or damage to the thymus by administering to the thymus an effective...
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